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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Mycograft 180 Tablet is used to prevent organ transplant rejection. It contains Mycophenolate sodium, which works by weakening the immune system and preventing it from rejecting the transplanted organ. In some cases, this medicine may cause side effects such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Whats That

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Manufacturer/Marketer :

Medgenix Pharma India Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mycograft 180 Tablet

Mycograft 180 Tablet is used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver. Transplant rejection occurs when the recipient’s immune system identifies the transplanted organ as a ‘foreign object’ and attacks it.

Mycograft 180 Tablet contains mycophenolate sodium, which works by suppressing the immune system, allowing the transplanted graft to avoid rejection.

In some cases, you may experience certain common side effects, such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Do not take Mycograft 180 Tablet if you are allergic to any of its ingredients. To avoid recurring symptoms, do not stop it midway. Do not take Mycograft 180 Tablet if you are pregnant or planning to become pregnant. Mycograft 180 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. Mycograft 180 Tablet should not be given to children as safety and efficacy have not been established.

Uses of Mycograft 180 Tablet

Mycograft 180 Tablet is used to prevent organ rejection in patients who have undergone a kidney, heart, or liver transplant. The detailed uses of Mycograft 180 Tablet are as follows:

  • Prevents organ rejection: Mycograft 180 Tablet helps avoid rejection episodes in patients following organ transplantation.
  • Used with other medications: Mycograft 180 Tablet is commonly administered alongside other immunosuppressants to enhance effectiveness.
  • Maintains graft function: Mycograft 180 Tablet supports the long-term survival of the transplanted organ by reducing immune activity.

Directions for Use

  • Mycograft 180 Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after eating or drinking.
  • Follow your doctor's instructions regarding the dosage and duration for effective results.
  • Swallow Mycograft 180 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Mycograft 180 Tablet contains Mycophenolate mofetil, an immunosuppressant used primarily in organ transplant recipients.
  • It helps the body accept transplanted organs (like the kidney, heart, or liver) by suppressing immune responses.
  • Mycograft 180 Tablet inhibits the function of white blood cells (T and B lymphocytes), which are responsible for attacking transplanted organs.
  • It enhances the long-term success of organ transplantation.
  • Mycograft 180 Tablet is often used along with other immunosuppressants like tacrolimus or cyclosporine for optimal effect.
  • Preferred over long-term use of corticosteroids due to fewer chronic side effects.

How Mycograft 180 Tablet Works

Mycograft 180 Tablet contains Mycophenolate sodium used in the treatment of organ transplant rejection, along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (white blood cells that attack foreign cells) and suppresses antibody production (identifies and kills foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Mycograft 180 Tablet
  • Drink more fluids as dehydration can decrease blood flow to kidneys and increase BUN levels.
  • Eat less protein and stop protein supplements as high protein diet may increase BUN levels.
  • Severe cases may require kidney transplant or dialysis.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • If you observe any new and unusual marks on your skin, discontine the drug and reach out to your doctor for advice.
  • If the cancer is in the early stage, your doctor may surgically remove the tumour.
  • Radiation, cancer medications, or targeted treatments may be recommended based on the severity of the cancer.
  • Consult a dietitian to make sure you are eating the right food and getting enough nutrition during cancer treatment.
  • Eat your meals in small amounts with a gap of 2-3 hours.
  • Do light physical activities to relieve tiredness and improve your overall well-being.

What if I have taken an overdose of Mycograft 180 Tablet

Take Mycograft 180 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, stomach pain, diarrhoea, heartburn, and signs of infection (fever, chills, cough, sore throat). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Mycograft 180 Tablet if you are allergic to any immunosuppressant medicines or mycophenolate sodium.
  • Let your doctor know before using Mycograft 180 Tablet if you have liver or kidney problems, severe digestive issues, cancer, liver disease (such as hepatitis B, hepatitis C), current/past infections, or rare genetic disorders (such as Lesch-Nyhan or Kelley-Seegmiller syndromes).
  • Do not take Mycograft 180 Tablet if you are pregnant or planning for pregnancy, as Mycograft 180 Tablet is a pregnancy category risk D medicine, which can cause serious congenital disabilities to the unborn baby.
  • Mycograft 180 Tablet should not be taken by breastfeeding mothers, as it passes into breast milk.
  • Pregnant women should use reliable forms of birth control while on treatment and for six weeks after stopping treatment with Mycograft 180 Tablet .
  • While taking Mycograft 180 Tablet , do not contact anyone who has shingles, chickenpox, or measles.
  • Mycograft 180 Tablet causes dizziness and drowsiness, so drive with caution.
  • Mycograft 180 Tablet should not be given to children as safety and efficacy have not been established.
  • Avoid consuming alcohol along with Mycograft 180 Tablet as it could lead to increased dizziness.
  • Your doctor may advise you to undergo regular blood tests and kidney and liver tests to monitor your condition.
  • Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Mycograft 180 Tablet .

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Mycograft 180 Tablet:
Coadministration of Colestipol with Mycograft 180 Tablet can reduce its absorption and action in the body. This can lead to low treatment results.

How to manage the interaction:
Taking Mycograft 180 Tablet with Colestipol is not recommended as it can result in an interaction, it can be taken if your doctor has advised it.
How does the drug interact with Mycograft 180 Tablet:
A combined use of Levonorgestrel with Mycograft 180 Tablet may reduce the blood levels and effects of levonorgestrel, which may make it less reliable as a form of birth control, Mycograft 180 Tablet may cause pregnancy loss in the first trimester and also birth defects in the unborn child.

How to manage the interaction:
There could be a possible interaction between Mycograft 180 Tablet and Levonorgestrel, but they can be taken together if a doctor has prescribed them. However, if you take hormone replacement (Levonorgestrel) for menopause, and if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mycograft 180 Tablet:
Coadministration of Mycograft 180 Tablet and Medicinal charcoal may decrease the levels and effects of Mycograft 180 Tablet.

How to manage the interaction:
There could be a possible interaction between Mycograft 180 Tablet and charcoal, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms, consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Mycograft 180 Tablet:
Taking Mycograft 180 Tablet and Alefacept can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
There could be a possible interaction between Mycograft 180 Tablet and Alefacept, but they can be taken together if your doctor has prescribed them. However, if you experience fever, chills, diarrhea, sore throat, body pains, shortness of breath, or burning urination consult a doctor. Do not discontinue any medications without a doctor's advice.
Mycophenolic acidEtonogestrel
Severe
How does the drug interact with Mycograft 180 Tablet:
Combine use of Etonogestrel with Mycograft 180 Tablet may decrease the serum concentration of Etonogestrel.

How to manage the interaction:
There could be a possible interaction between Mycograft 180 Tablet and Etonogestrel, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mycograft 180 Tablet:
Coadministration of Baricitinib and Abatacept can increase the risk of developing serious infections.

How to manage the interaction:
Taking Baricitinib and Abatacept together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Mycograft 180 Tablet:
Coadministration of Mycograft 180 Tablet and Colestyramine can decrease the effect of Mycograft 180 Tablet.

How to manage the interaction:
There could be a possible interaction between Mycograft 180 Tablet and Cholestyramine, it can be taken together if your doctor has prescribed them. However, if you experience fever, diarrhea, sore throat, muscle aches, shortness of breath, inflamed skin, body pain, or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mycograft 180 Tablet:
Coadministration of Mycograft 180 Tablet and Desogestrel can decrease the levels and action of Desogestrel.

How to manage the interaction:
Co-administration of Desogestrel with Mycograft 180 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms: abnormal menstruation, dryness of the vagina, or increased hot flushes or if you're looking for other birth control options, consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mycograft 180 Tablet:
Co-administration of Ferrous sulfate with Mycograft 180 Tablet decreases levels of Mycophenolate by reducing its absorption.

How to manage the interaction:
There could be a possible interaction between Mycograft 180 Tablet and Ferrous sulfate, but they can be taken together if a doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhea, constipation sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, or feet, joint pain, cough, or shortness of breath consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Mycograft 180 Tablet:
Taking Mycograft 180 Tablet and Golimumab can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
There could be a possible interaction between Mycograft 180 Tablet and Golimumab, but they can be taken together if your doctor has prescribed them. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help improve joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Mycograft 180 Tablet . It could lead to increased dizziness and drowsiness.

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Pregnancy

Unsafe

Mycograft 180 Tablet may cause birth defects and miscarriage if taken during pregnancy. Follow the contraception advice given by your doctor if you are a woman who could become pregnant. Also, undergo a pregnancy test before starting treatment with Mycograft 180 Tablet .

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Breast Feeding

Unsafe

It is not recommended to take Mycograft 180 Tablet while you are breastfeeding. Mycograft 180 Tablet passes into breast milk.

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Driving

Unsafe

Mycograft 180 Tablet may cause dizziness, tiredness. Do not drive or operate heavy machinery if you feel dizzy.

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Liver

Consult your doctor

Consult the doctor if you have liver diseases/conditions, as your doctor may adjust the dose as required.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment before taking Mycograft 180 Tablet as your doctor may adjust the dose as required.

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Children

Unsafe

Mycograft 180 Tablet should not be used by children below 18 years of age, as the efficacy and safety have not been established.

Have a query?

FAQs

Mycograft 180 Tablet is used to prevent the body from rejecting a transplanted organ such as a kidney, heart‚ or liver.

Mycograft 180 Tablet belongs to the group of medications called immunosuppressants. It works by weakening the immune system by inhibiting the production of cells or antibodies that attack foreign cells. This effect helps in stopping the immune system from targeting and rejecting the transplanted organ.

Mycograft 180 Tablet causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infection, such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Diarrhoea might be a side-effect of Mycograft 180 Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Mycograft 180 Tablet can suppress the immune system and can increase the risk of skin cancer. So, it would be best if you avoid prolonged exposure to sunlight. Also, wear protective clothing covering your head, neck, arms and legs, and use a sunscreen lotion with a high SPF (sun protection factor).

Mycograft 180 Tablet can suppress the immune system. You should not donate blood while using Mycograft 180 Tablet and for at least 60 days after stopping treatment, as it makes you more prone to infections. Besides, men should not donate sperm while using Mycograft 180 Tablet for at least 90 days after stopping the treatment.

Some medicines might absorb mycophenolate sodium more slowly or faster if taken concomitantly, such as antacids containing aluminium or magnesium, colestipol, cholestyramine, or calcium-free phosphate binders. Before taking Mycograft 180 Tablet , speak with your doctor about your ongoing medication list. Your doctor will decide whether they should be taken along with Mycograft 180 Tablet .

The live vaccine may not work while on treatment with Mycograft 180 Tablet . Do not have immunisations/vaccinations without talking to your doctor first. Also, avoid contact with people who have recently had immunisations/vaccinations.

Mycograft 180 Tablet may cause side effects such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Talk to your doctor if you experience these side effects persistently.

Mycograft 180 Tablet should be swallowed as a whole with water; do not crush or chew it. Mycograft 180 Tablet should be taken on an empty stomach (1 hour before or 2 hours after eating or drinking) or as advised by the doctor.

Avoid prolonged or unnecessary exposure to sunlight (sunlamps, tanning beds) and light therapy and wear protective clothing, sunscreen, and sunglasses. This will help lower your risk of developing skin cancer.

Your doctor has prescribed Mycograft 180 Tablet to suppress the immunity and prevent the rejection of the transplanted kidney.

Mycograft 180 Tablet may increase the risk of skin cancer as it reduces the body’s defences. Limit the amount of sunlight and UV light, wear protective clothing and use sunscreen with high SPF.

Mycograft 180 Tablet is not a steroid or chemotherapy medicine. It is an immunosuppressant used to prevent organ rejection after a transplant.

Mycograft 180 Tablet may cause skin problems such as hair loss. Talk to the doctor if you have any concerns.

The doctor may recommend regular blood tests to check for signs of infection and to monitor the blood count. Women of childbearing potential must provide a negative pregnancy test before the start of treatment.

As Mycograft 180 Tablet reduces the body’s defences, you may be at a higher risk of developing infections. Therefore, your doctor has asked you to stay away from a person who has chickenpox or shingles.

Mycograft 180 Tablet causes a high frequency of miscarriage and birth defects. Therefore, before the start of treatment, women of childbearing potential must provide a negative pregnancy test. Also, women who can become pregnant should use effective contraception during treatment and for 6 months after stopping Mycograft 180 Tablet . Two forms of contraception are preferable as this will reduce the risk of unintended pregnancy. Contact the doctor about the effective methods of contraception.

As a precaution, the male or his female partner must use reliable contraception during treatment and for 90 days after stopping Mycograft 180 Tablet .

Country of origin

India

Manufacturer/Marketer address

H.No:1-8-32/47, 1St Floor Bapu Bagh, Pg Road, Secunderabad Hyderabad Hyderabad Tg 500003 In
Other Info - MYC0161

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