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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Murinact Sachet 8 gm is used to treat or prevent bladder infections. It contains Fosfomycin, which kills bacteria. Also, it decreases the attachment of bacteria to cells lining the urinary bladder, thereby preventing bladder infection caused by E.coli bacteria. In some cases, you may experience side effects such as dizziness, headache, indigestion, and vulvovaginitis (swelling or infection of the vulva and vagina). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Whats That

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Synonym :

FOSFOMYCIN TROMETAMOL

Composition :

FOSFOMYCIN-3000MG

Manufacturer/Marketer :

Fusion Health Care Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Murinact Sachet 8 gm

Murinact Sachet 8 gm is an antibiotic used to treat or prevent bladder infections. Bladder infection is mostly caused by a bacterial infection within the bladder. Bacteria enter through the urethra, move into the bladder and cause infections.

Murinact Sachet 8 gm contains Fosfomycin, which inhibits the formation of the bacterial cell wall (a protective covering) necessary for survival. Thus, it kills bacteria. Also, Murinact Sachet 8 gm decreases the attachment of bacteria to cells lining the urinary bladder, thereby preventing bladder infection caused by E.coli bacteria. 

Take Murinact Sachet 8 gm as prescribed by your doctor. You are advised to take Murinact Sachet 8 gm for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience dizziness, headache, indigestion, and vulvovaginitis (swelling or infection of the vulva and vagina) as side effects of Murinact Sachet 8 gm. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Murinact Sachet 8 gm, some sugars or other medicines. If you are pregnant or breastfeeding, please inform your doctor before taking Murinact Sachet 8 gm. Murinact Sachet 8 gm is not recommended for children below 12 years of age. Murinact Sachet 8 gm is contraindicated in patients with severe kidney problems and patients undergoing hemodialysis (a process of purifying blood by filtering out extra fluids and wastes when kidneys are not working). If you previously had diarrhoea caused by other antibiotics, inform your doctor before taking Murinact Sachet 8 gm.

Uses of Murinact Sachet 8 gm

Murinact Sachet 8 gm is used in the treatment of Bladder infection. The detailed uses of Murinact Sachet 8 gm are as follows: <br/> • Treatment of Urinary Tract Infections: Murinact Sachet 8 gm is used to treat uncomplicated urinary tract infections (UTIs) caused by susceptible bacteria.<br/>• Treatment of Cystitis: Murinact Sachet 8 gm is utilized in managing cystitis, which is the inflammation of the bladder, often linked with bacterial infections.<br/> • Prevention of Urinary Tract Infections: In some cases, Murinact Sachet 8 gm may be used preventively for patients at high risk of recurrent urinary tract infections.<br/> • Post-Surgical UTI Prevention: Murinact Sachet 8 gm is used for post-surgical UTI prevention in patients undergoing certain procedures.<br/>

Directions for Use

• Murinact Sachet 8 gm can be taken with or without food as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety. • Swallow Murinact Sachet 8 gm as a whole with a glass of water. • Do not chew, crush or break it.

Medicinal Benefits

Murinact Sachet 8 gm includes Fosfomycin, a broad-spectrum antibiotic that kills gram-negative and gram-positive bacteria that grow aerobically (in the presence of oxygen) and anaerobically (in the absence of oxygen). Murinact Sachet 8 gm prevents the formation of the necessary bacterial cell wall (a protective covering) for survival. As a result, it kills bacteria. Additionally, Murinact Sachet 8 gm inhibits bacterial attachment to cells lining the urinary bladder, preventing bladder infection caused by E.coli bacteria.

How Murinact Sachet 8 gm Works

Murinact Sachet 8 gm contains Fosfomycin, which inhibits the formation of the bacterial cell wall (a protective covering) necessary for survival. Thus, it kills bacteria. Also, Murinact Sachet 8 gm decreases the attachment of bacteria to cells lining the urinary bladder, thereby preventing bladder infection caused by E.coli bacteria.

Storage

Keep Murinact Sachet 8 gm out of reach and sight of children.
Side effects of Murinact Sachet 8 gm
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Red rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Use a warm compress on the affected area to help reduce discomfort.
  • Elevate the affected limb above heart level.
  • Remove the IV catheter (if applicable) and reinsert at a different site.
  • Consult your healthcare provider if symptoms are severe or persist.

What if I have taken an overdose of Murinact Sachet 8 gm

Do not take more than the prescribed dose of Murinact Sachet 8 gm as it may cause overdose. The symptoms of overdose include altered sense of taste or hearing problems. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Please tell your doctor if you are allergic to Murinact Sachet 8 gm, some sugars or other medicines. If you are pregnant or breastfeeding, please inform your doctor before taking Murinact Sachet 8 gm. Murinact Sachet 8 gm is not recommended for children below 12 years of age. Murinact Sachet 8 gm is contraindicated in patients with severe kidney problems and patients undergoing hemodialysis (a process of purifying blood by filtering out extra fluids and wastes when kidneys are not working). Contact your doctor immediately if you notice blood in the stools or have severe stomach pain with diarrhoea. If you previously had diarrhoea caused by other antibiotics, inform your doctor before taking Murinact Sachet 8 gm.

Drug-Drug Interactions

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FosfomycinBCG vaccine
Severe

Drug-Drug Interactions

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FosfomycinBCG vaccine
Severe
How does the drug interact with Murinact Sachet 8 gm:
When BCG vaccine is used with Murinact Sachet 8 gm, its effectiveness may be reduced.

How to manage the interaction:
Taking Murinact Sachet 8 gm with the BCG vaccine can lead to an interaction, please consult a doctor before taking it.
How does the drug interact with Murinact Sachet 8 gm:
Murinact Sachet 8 gm may reduce the effect of balsalazide when taken orally.

How to manage the interaction:
If you are supposed to take Murinact Sachet 8 gm and Balsalazide together, your doctor may adjust the dose or monitor you more frequently to use both medications safely.
FosfomycinCholera vaccines
Severe
How does the drug interact with Murinact Sachet 8 gm:
Co-administration of the Cholera vaccine with Murinact Sachet 8 gm may reduce the activity of the Cholera vaccine.

How to manage the interaction:
If you are currently being treated with Murinact Sachet 8 gm or have been treated within the last 14 days, inform your doctor before receiving cholera vaccine, live. Avoid receiving cholera vaccine, live until at least 14 days after you complete your antibiotic therapy to ensure adequate vaccine response.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid alcohol, soda, coffee, tea, and artificial sweeteners, as they may cause bladder irritation.
  • Drink plenty of water or other fluids daily while taking Murinact Sachet 8 gm to flush out the bacteria.
  • Avoid spicy foods and citrus fruits (lemons, oranges, grapefruits) as they may irritate the bladder.
  • Eat foods antioxidant-rich foods such as blueberries, cranberries, tomatoes, spinach, broccoli, and plain greek yoghurt.
  • Take probiotics after completing the entire course of Murinact Sachet 8 gm to restore some good bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut and kimchi can help restore the intestine's good bacteria. 
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet. 

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Caution

The interaction of alcohol with Murinact Sachet 8 gm is unknown. However, limit or avoid consumption of alcohol while taking Murinact Sachet 8 gm.

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Pregnancy

Caution

Murinact Sachet 8 gm is a category B pregnancy drug and is given to pregnant women only if the doctor thinks the benefits outweigh the risks. Therefore, please inform your doctor if you are pregnant or planning pregnancy before taking Murinact Sachet 8 gm.

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Breast Feeding

Caution

Small amounts of Murinact Sachet 8 gm are excreted in human milk. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Murinact Sachet 8 gm may cause dizziness or tiredness in some people. Therefore, avoid driving if you experience any of these symptoms after taking Murinact Sachet 8 gm.

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Liver

Caution

Limited information is available on the effect of Murinact Sachet 8 gm in patients with liver disease. Therefore, inform your doctor if you have any liver diseases/conditions before taking this medicine.

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Kidney

Caution

Murinact Sachet 8 gm is not recommended if you have severe kidney problems or are undergoing hemodialysis. Inform your doctor if you have any Kidney problems before taking Murinact Sachet 8 gm.

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Children

Unsafe

Murinact Sachet 8 gm is not recommended for children below 12 years of age as the safety and effectiveness were not established.

Have a query?

FAQs

Murinact Sachet 8 gm is used to treat or prevent bladder infections.

Murinact Sachet 8 gm contains Fosfomycin, which inhibits the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thus, it kills bacteria. Also, Murinact Sachet 8 gm decreases the attachment of bacteria to cells lining the urinary bladder.

Murinact Sachet 8 gm is not recommended in patients undergoing hemodialysis (a process of purifying blood by filtering out extra fluids and wastes when kidneys are not working) as the excretion of Murinact Sachet 8 gm may be reduced in such patients leading to the accumulation of Murinact Sachet 8 gm in the body. Therefore, please inform your doctor if you are undergoing hemodialysis before taking Murinact Sachet 8 gm so that alternative medicine may be prescribed.

Yes, Murinact Sachet 8 gm may cause headaches as a common side effect. However, if the condition persists or worsens, please consult a doctor.

You are not recommended to take Murinact Sachet 8 gm with metoclopramide as co-administration of these two medicines may reduce the absorption of Murinact Sachet 8 gm. However, please consult your doctor before taking Murinact Sachet 8 gm with other medicines.

You are not recommended to stop taking Murinact Sachet 8 gm without consulting your doctor, as it may worsen the infection or cause recurring symptoms. Therefore, complete the full course of antibiotics and take Murinact Sachet 8 gm for as long as your doctor has prescribed it, and if you experience any difficulty while taking Murinact Sachet 8 gm, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Other Info - MUR0054

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