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compositionComposition:MYCOPHENOLIC ACID-250MG
prescriptionPrescription Medicine
Mofetyl 250 Tablet 10's

Mofetyl 250 Tablet contains Mycophenolic acid, which is used to prevent rejection of a transplanted organ such as a liver, kidney, or heart. It belongs to the class of immunosuppressants that work by decreasing the production of white blood cells in the body, helping the body accept the new organ.

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Written By Lakshmithulasi Yarragunta ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MYCOPHENOLIC ACID-250MG

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

NPPA :

Regulated

About Mofetyl 250 Tablet

Mofetyl 250 Tablet belongs to a class of drugs called immunosuppressants. These drugs are used to prevent rejection of a transplanted organ such as a liver, kidney, or heart. Organ rejection occurs when a patient’s immune system recognises the donor organ as foreign and tries to eliminate it.

Mofetyl 250 Tablet contains Mycophenolic acid, which decreases the production of white blood cells that usually attack foreign invaders and defend the body against foreign cells and infection. As a result, it prevents organ rejection in transplanted patients and helps the body accept the new organ.

Common side effects of Mofetyl 250 Tablet may include stomach pain, vomiting, diarrhoea, high blood pressure, or swelling of the lower legs, feet, and ankles. Most of these side effects of Mofetyl 250 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to medicines or food products. If you are pregnant or a breastfeeding mother, it is advised to inform your doctor before taking Mofetyl 250 Tablet . You or your partner is advised to use effective contraceptive measures before starting treatment with Mofetyl 250 Tablet or for 90 days after treatment with Mofetyl 250 Tablet .

Limit or avoid alcohol consumption with Mofetyl 250 Tablet as it may increase the risk of liver damage. Drive only if you are alert after taking Mofetyl 250 Tablet , as it may cause drowsiness, confusion, or numbness in a few patients.

Uses of Mofetyl 250 Tablet

Mofetyl 250 Tablet is used to prevent transplanted organ rejection. The detailed uses of Mofetyl 250 Tablet are as follows:

  • Prevents Organ Rejection: Mofetyl 250 Tablet is used along with other immunosuppressants to help prevent the rejection of transplanted organs such as the kidney, liver, or heart by weakening the body's immune response.
  • Suppresses Immune System Activity: Mofetyl 250 Tablet inhibits the proliferation of specific white blood cells (T and B lymphocytes), which are responsible for attacking transplanted organs.

Key Benefits

  • Prevents organ rejection after kidney, heart, or liver transplantation.
  • Suppresses the immune system to stop it from attacking the transplanted organ.
  • Reduces the activity of T and B lymphocytes that trigger immune responses.
  • Helps manage autoimmune diseases such as lupus nephritis and rheumatoid arthritis.
  • Decreases inflammation caused by immune overactivity.
  • Improves long-term graft survival when used with other immunosuppressants.
  • Helps maintain immune balance while minimising the risk of rejection or excessive suppression.
Side effects of Mofetyl 250 Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in white blood cells which may lead to impaired immunity.
  • Stay hydrated to support kidney and bladder health.
  • Rest on your back as advised by your doctor.
  • Limit physical strain for 1-2 weeks.
  • Avoid strenuous activities like running and contact sports.
  • Quit smoking to improve overall health.
  • Use pain medication responsibly.
  • Avoid foods that can irritate the urinary track, such as spicy or acidic foods.
  • Remember to consult your doctor for personalized advice and guidance on managing your symptoms and developing a treatment plan.

Directions for Use

  • Mofetyl 250 Tablet should be taken on an empty stomach, at least 1 hour before or 2 hours after a meal.
  • It is usually taken twice daily or as prescribed by your doctor.
  • Swallow Mofetyl 250 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Mofetyl 250 Tablet Works

Mofetyl 250 Tablet contains Mycophenolic acid, which decreases the production of white blood cells that usually attack foreign invaders and defend the body against them. As a result, it prevents organ rejection in transplanted patients and helps the body accept the new organ.
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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Mofetyl 250 Tablet . It could lead to increased dizziness and drowsiness.

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Pregnancy

Unsafe

Mofetyl 250 Tablet may cause birth defects and miscarriage if taken during pregnancy. Follow the contraception advice given by your doctor if you are a woman who could become pregnant. Also, undergo a pregnancy test before starting treatment with Mofetyl 250 Tablet .

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Breast Feeding

Unsafe

It is not recommended to take Mofetyl 250 Tablet while you are breastfeeding. Mofetyl 250 Tablet passes into breast milk.

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Driving

Caution

Mofetyl 250 Tablet may cause dizziness and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Take Mofetyl 250 Tablet only as directed by your doctor, especially if you have liver disease, as your doctor may adjust the dose as required.

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Kidney

Caution

Take Mofetyl 250 Tablet only as directed by your doctor, especially if you have kidney disease, as your doctor may adjust the dose as required.

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Children

Unsafe

Mofetyl 250 Tablet should not be used by children and adolescents under 18 years of age, as its efficacy and safety have not been established.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Mofetyl 250 Tablet . Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Mofetyl 250 Tablet in elderly patients. Please consult your doctor.

What if I have taken an overdose of Mofetyl 250 Tablet

Take Mofetyl 250 Tablet only as prescribed by the physician. Avoid exceeding the recommended dose, as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, stomach pain, diarrhoea, heartburn, and signs of infection (fever, chills, cough, sore throat). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

  • Physical activity strengthens muscles and relieves joint stiffness. Gentle activities, such as 20-30 minutes of walking or swimming, are helpful.
  • Performing yoga may also help improve joint flexibility and manage pain.
  • Maintain a healthy weight by engaging in regular low-impact exercises and eating nutritious foods.
  • Get adequate sleep, as resting the muscles can help reduce inflammation and swelling.
  • Follow heat or cold therapy and regularly apply a cold or hot compress to the joints for 15-20 minutes.
  • De-stress yourself by meditating, reading books, taking a warm bubble bath, or listening to soothing music.
  • Acupuncture, massage, and physical therapy may also be helpful.
  • Eat foods rich in antioxidants, such as berries, spinach, kidney beans, and dark chocolate.
  • Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.
  • Avoid smoking and alcohol consumption.

Have a query?

How Soon It Starts Working

  • The time required for Mofetyl 250 Tablet to start to work: Mofetyl 250 Tablet ideally shows its action within 60 to 90 minutes after administration.
  • The time for which the effects of Mofetyl 250 Tablet last: The effect of Mofetyl 250 Tablet lasts for 8 to 16 hours.

What if you forget to take Mofetyl 250 Tablet

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and follow your regular dosing schedule. Do not take a double dose to make up for your missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep Mofetyl 250 Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Please tell your doctor if you are allergic to any medicines or foods.
  • If you are pregnant or a breastfeeding mother, it is advised to inform your doctor before taking Mofetyl 250 Tablet .
  • You or your partner are advised to use effective contraceptive measures before starting treatment with Mofetyl 250 Tablet , while taking Mofetyl 250 Tablet and for 90 days after stopping treatment with Mofetyl 250 Tablet .
  • Limit or avoid alcohol consumption with Mofetyl 250 Tablet as it may increase the risk of liver damage.
  • Drive only if you are alert after taking Mofetyl 250 Tablet , as it may cause drowsiness, confusion or numbness in some patients.
  • If you are about to get vaccinated, inform your doctor before taking Mofetyl 250 Tablet .
  • Mofetyl 250 Tablet may increase the risk of infections or skin cancer by weakening the body’s immune defence system.
  • While taking Mofetyl 250 Tablet , you are advised to wear protective clothing and use sunscreen while going out.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Mofetyl 250 Tablet may interact with various medications, including antibiotics (e.g., amoxicillin, azithromycin), vaccinations (e.g., BCG vaccine, cholera vaccine live), immunosuppressive medications (e.g., etanercept), hormonal medications (e.g., levonorgestrel, norethindrone), and antimicrobials (e.g., tinidazole).

Drug-Food Interactions: Avoid alcohol consumption while taking Mofetyl 250 Tablet as it may increase dizziness.

Drug-Disease Interactions: Mofetyl 250 Tablet may interact with conditions such as cancer, liver disease (including hepatitis B and hepatitis C), current/past infections, serious digestive problems, and rare genetic disorders (such as Lesch-Nyhan or Kelley-Seegmiller syndromes).

Mycophenolate MofetilClozapine
Severe
Mycophenolate MofetilInfliximab
Severe

Drug-Drug Interactions

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Mycophenolate MofetilClozapine
Severe
How does the drug interact with Mofetyl 250 Tablet:
Combining Clozapine and Mofetyl 250 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
There may be a possibility of interaction between Clozapine and Mofetyl 250 Tablet, but it can be taken if prescribed by a doctor. If you're having any of these symptoms like fever, chills, sore throat, or muscle aches, it's important to contact your doctor right away. They may be able to recommend other options for you that won't cause any problems. Don't worry, there are solutions available to help you feel better. Do not discontinue any medications without first consulting your doctor.
Mycophenolate MofetilInfliximab
Severe
How does the drug interact with Mofetyl 250 Tablet:
Combining Infliximab and Mofetyl 250 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Mofetyl 250 Tablet and Infliximab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilCholestyramine
Severe
How does the drug interact with Mofetyl 250 Tablet:
Co-administration of cholestyramine and Mofetyl 250 Tablet may interfere with the action of Mofetyl 250 Tablet.

How to manage the interaction:
Although taking cholestyramine and Mofetyl 250 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. Do not stop using any medications without consulting a doctor.
Mycophenolate MofetilDeferiprone
Severe
How does the drug interact with Mofetyl 250 Tablet:
Combining Deferiprone and Mofetyl 250 Tablet can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Mofetyl 250 Tablet and Deferiprone together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilVoclosporin
Severe
How does the drug interact with Mofetyl 250 Tablet:
Using voclosporin together with Mofetyl 250 Tablet may increase the risk of serious infections.

How to manage the interaction:
Although taking Mofetyl 250 Tablet and Voclosporin together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilNatalizumab
Severe
How does the drug interact with Mofetyl 250 Tablet:
Using natalizumab together with Mofetyl 250 Tablet may increase the risk of developing serious infections.

How to manage the interaction:
Although taking Mofetyl 250 Tablet and Natalizumab together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilColestipol
Severe
How does the drug interact with Mofetyl 250 Tablet:
Combining Mofetyl 250 Tablet and Colestipol may interfere with the absorption of Mofetyl 250 Tablet. This can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Mofetyl 250 Tablet and Colestipol together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience Nausea or vomiting, headache, drowsiness, dry mouth, fainting, fast, slow, pounding, or irregular heartbeat or pulse, fever or chills call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilTeriflunomide
Severe
How does the drug interact with Mofetyl 250 Tablet:
Using teriflunomide together with Mofetyl 250 Tablet may increase the risk of developing serious infections.

How to manage the interaction:
Although taking Mofetyl 250 Tablet and Teriflunomide together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination call a doctor right away. Do not discontinue any medications without consulting a doctor.
Mycophenolate MofetilLevonorgestrel
Severe
How does the drug interact with Mofetyl 250 Tablet:
Taking Levonorgestrel with Mofetyl 250 Tablet can decrease the levels of Levonorgestrel in the body. This increases the risk of severe bleeding and unintended pregnancy.

How to manage the interaction:
Although taking Mofetyl 250 Tablet and Levonorgestrel together can cause an interaction, it can be taken if a doctor has suggested it. Contact a doctor if you experience worsening of your symptoms such as hot flashes, vaginal dryness, or abnormal bleeding. Do not discontinue any medication without consulting a doctor.
Mycophenolate MofetilColestyramine
Severe
How does the drug interact with Mofetyl 250 Tablet:
Coadministration of Mofetyl 250 Tablet and Colestyramine may decrease the blood levels of Mofetyl 250 Tablet.

How to manage the interaction:
Although taking Cholestyramine and Mofetyl 250 Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience Constipation, Diarrhea, Stomach pain, Nausea, or Loss of appetite, consult a doctor. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[IMMUNOSUPPRESSANTS]

FAQs

Mofetyl 250 Tablet belongs to the class of medicines called immunosuppressants, used to prevent organ rejection after a kidney transplant.

Mofetyl 250 Tablet may cause leukopenia (a decrease in white blood cell count) and make you more susceptible to infections. Consult your doctor if you develop any signs of infection, such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.

If you miss a dose of Mofetyl 250 Tablet , take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.

Diarrhoea might be a side-effect of Mofetyl 250 Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in your stools (tarry stools) or if you experience prolonged diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Mofetyl 250 Tablet works by modulating the immune system's response to the transplanted organ and is given along with other immunosuppressant medications.

Some medicines might affect mycophenolic acid absorption more slowly or faster when taken concomitantly, such as antacids containing aluminium or magnesium, colestipol, cholestyramine, or calcium-free phosphate binders. Before taking Mofetyl 250 Tablet , speak with your doctor about your ongoing medication list. Your doctor will decide whether they should be taken with Mofetyl 250 Tablet .

The live vaccine may not work well while on treatment with Mofetyl 250 Tablet . Do not have immunisations/vaccinations without talking to your doctor first. Also, avoid contact with people who have recently had immunisations/vaccinations.

Mofetyl 250 Tablet may increase your risk of developing certain cancers. It is essential to talk to your doctor regularly about your risk of cancer and any symptoms you might be experiencing.

Mofetyl 250 Tablet is a common immunosuppressant medication prescribed after a kidney transplant. Its primary purpose is to prevent your body from rejecting the transplanted kidney.

Mofetyl 250 Tablet is neither a steroid nor a chemotherapy medication. It's an immunosuppressant, which means it works by suppressing the immune system to prevent organ rejection. Regarding hair loss, MPA can sometimes cause hair loss as a side effect. However, this is not a common side effect, and hair loss is usually resolved after the medication is stopped or the dosage is adjusted.

While taking Mofetyl 250 Tablet , you will likely need to undergo regular tests. These tests help monitor your kidney function, blood cell counts, and overall health.

Immunosuppressants like Mofetyl 250 Tablet are essential for preventing organ rejection, but they can also compromise your immune system, increasing your risk of infections. Viral infections like chickenpox and shingles, caused by the varicella-zoster virus, can pose a significant health threat to individuals with weakened immune systems. If you're exposed to someone with these conditions, seek immediate medical advice. Your doctor may recommend preventive measures, such as antiviral medications, to reduce your risk of complications.

Women taking Mofetyl 250 Tablet should avoid pregnancy, as it can harm the fetus. Effective birth control is crucial. If pregnancy occurs, stop the medication immediately and consult a doctor. Additionally, breastfeeding should be avoided due to the risk of medication passing through breast milk. Regular check-ups, informing healthcare providers, and monitoring for side effects are essential.

Men should be aware of the potential for reduced sperm count and fertility while taking this medication. Discuss this with your doctor if you plan to start a family. It's also important to use effective birth control to prevent pregnancy in your female partner. Regular check-ups and monitoring for side effects are essential. If you have concerns, consult your doctor.

No, you should never stop taking Mofetyl 250 Tablet without consulting your doctor. Sudden discontinuation can lead to organ rejection.

It's essential to consult your doctor before taking any over-the-counter medicines while on Mofetyl 250 Tablet . Some medications may interact with it and affect its effectiveness.

Common side effects of Mofetyl 250 Tablet may include stomach pain, vomiting, diarrhoea, high blood pressure, or swelling of the lower legs, feet, and ankles. Most of the side effects of Mofetyl 250 Tablet do not require medical attention and resolve gradually over time. However, if these side effects persist or worsen, please consult your doctor.

Yes, Mofetyl 250 Tablet can interact with other medications, especially other immunosuppressants, antibiotics, and antifungal agents. Discuss all the medications you are taking with your doctor and seek appropriate advice.

It's generally recommended to avoid excessive alcohol consumption while taking Mofetyl 250 Tablet , as it can increase the risk of side effects.

If you have other health conditions, such as diabetes or heart disease, discuss them with your doctor before starting Mofetyl 250 Tablet . Your doctor will weigh the benefits and potential risks before prescribing Mofetyl 250 Tablet .

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

463, 4 Th Floor, Rpg House, Dr. Annie Besant Road, Worli, Mumbai €“ 400 030. Maharashtra, India
Other Info - MOF0072
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