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compositionComposition:INSULIN HUMAN-30%+INSULIN ISOPHANE-70%
prescriptionPrescription Medicine
Mixtard 30 Flexpen 100 IU Injection 3 ml
Mixtard 30 Flexpen 100 IU Injection 3 ml
Mixtard 30 Flexpen 100 IU Injection 3 ml
Mixtard 30 Flexpen 100 IU Injection 3 ml

Mixtard 30 Flexpen 100 IU Injection 3 ml is used for the treatment of both type 1 and type 2 diabetes mellitus. It maintains blood sugar levels in adults and children. It helps to lower the blood sugar (glucose) level by facilitating the uptake of glucose. It is followed by the binding of insulin to the cells of muscle and fat cells, thereby inhibiting glucose release from the liver. Thus, it helps to decrease blood glucose levels after the intake of meals. It may cause side effects such as allergic reaction at the site of injection, hypoglycemia (low blood glucose level), itching, lipodystrophy (skin thickening or pits at the injection site), oedema (swelling), rashes, and weight gain.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

INSULIN HUMAN-30%+INSULIN ISOPHANE-70%

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Mixtard 30 Flexpen 100 IU Injection 3 ml

Mixtard 30 Flexpen 100 IU Injection 3 ml is primarily used for the treatment of both type 1 and type 2 diabetes mellitus. Diabetes mellitus is a condition that affects the way your body processes glucose. Type 1 diabetes is an autoimmune disease where the body stops producing insulin. Type 2 diabetes is a metabolic disorder where the body resists insulin or doesn't produce enough insulin.

Mixtard 30 Flexpen 100 IU Injection 3 ml is a combination of insulin human and the other is insulin isophane. Insulin is a hormone made in your pancreas, which helps your body utilise glucose (sugar) for energy. Insulin Isophane contains human insulin, used to improve blood sugar control in adults and children.

Take Mixtard 30 Flexpen 100 IU Injection 3 ml as prescribed by your doctor. You are advised to take Mixtard 30 Flexpen 100 IU Injection 3 ml as long as your doctor has prescribed it for you, depending on your medical conditions.

You may experience an allergic reaction at the site of injection, hypoglycemia, itching, lipodystrophy (skin thickening or pits at the injection site), oedema, rashes, and weight gain. Most of these side effects of Mixtard 30 Flexpen 100 IU Injection 3 ml do not require medical attention. However, if the side effects are persistent, reach out to your doctor.

Do not take this medicine if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription or recreational drugs. Along with this medicine, you should take a healthy diet, do regular exercise, and maintain your weight as advised by your doctor.

Uses of Mixtard 30 Flexpen 100 IU Injection 3 ml

Mixtard 30 Flexpen 100 IU Injection 3 ml is used in the treatment of diabetes mellitus (type 1 and type 2). The detailed uses of Mixtard 30 Flexpen 100 IU Injection 3 ml are as follows:

  • Provides Effective Blood Sugar Control: Mixtard 30 Flexpen 100 IU Injection 3 ml contains a combination of short-acting (Insulin Human) and intermediate-acting (Insulin Isophane) insulin, which helps to replace the insulin normally produced by the body, allowing glucose to enter cells for energy and thereby lowering blood sugar levels.
  • Prevents Diabetes-Related Complications: By maintaining stable blood sugar, Mixtard 30 Flexpen 100 IU Injection 3 ml helps to reduce the risk of long-term complications like kidney damage, nerve problems, and cardiovascular diseases.

Key Benefits

  • When you take Mixtard 30 Flexpen 100 IU Injection 3 ml, it works by ensuring rapid and consistent sugar control.
  • It facilitates the reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.
  • It reduces the chances of developing serious complications of diabetes.
  • Besides this, Mixtard 30 Flexpen 100 IU Injection 3 ml can be safely prescribed to the diabetic mother during pregnancy as well as during lactation.
  • Mixtard 30 Flexpen 100 IU Injection 3 ml helps in improving glycemic control, which in turn decreases the risk of progression of complications of diabetes like damage to the retina (retinopathy), damage to the kidney (nephropathy), damage to the nerve cells (neuropathy), delayed wound healing, diabetic foot ulcer, and others.
Side effects of Mixtard-30 Flexpen 100iu Prefilled Pen 3ml
  • If you experience low blood sugar levels, inform your doctor. They will assess the severity and make recommendations for the next actions.
  • Your doctor will assess your symptoms, blood sugar levels, and overall health before recommending the best course of action, which may include treatment, lifestyle modifications, or prescription adjustments.
  • Follow your doctor's instructions carefully to manage the episode and adjust your treatment plan.
  • Make medication adjustments as recommended by your doctor to prevent future episodes.
  • Implement diet and lifestyle modifications as your doctor advises to manage low blood sugar levels.
  • Monitor your blood sugar levels closely for patterns and changes.
  • Track your progress by recording your blood sugar levels, food intake, and physical activity.
  • Seek further guidance from your doctor if symptoms persist or worsen so that your treatment plan can be revised.
Managing Medication-Related Skin Allergies: A Step-by-Step Guide
  • If you experience signs of skin allergies such as redness, itching, or irritation after taking medication, contact your doctor right away.
  • To alleviate skin allergy symptoms, your doctor may change your medication regimen or offer tailored medication management advice.
  • Your doctor may recommend or prescribe drugs to relieve discomfort.
  • Cool compresses or calamine lotion can help relieve redness and itching on the afflicted skin area.
  • Staying hydrated by consuming plenty of water can help relieve discomfort.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.

Directions for Use

  • Mixtard 30 Flexpen 100 IU Injection 3 ml should be administered approximately 30-45 minutes before a meal as prescribed by the doctor.
  • Administer Mixtard 30 Flexpen 100 IU Injection 3 ml subcutaneously as instructed by the doctor. Your doctor will train you on how to use Mixtard 30 Flexpen 100 IU Injection 3 ml at home.
  • Check the label for directions and use it as advised by the doctor. Mixtard 30 Flexpen 100 IU Injection 3 ml should be administered subcutaneously (under the skin) in the thighs, abdomen, buttocks, or upper arm.
  • Rotate the injection site each time.
  • Do not inject into the areas where the skin is tender, red, bruised, hard, scarred or has stretch marks.

How Mixtard 30 Flexpen 100 IU Injection 3 ml Works

Insulin Isophane contains human insulin, used to improve blood sugar control in adults and children with type 1 and type 2 diabetes mellitus. It maintains blood sugar levels in both adults and children. Mixtard 30 Flexpen 100 IU Injection 3 ml helps to lower the blood sugar (glucose) level by facilitating the uptake of glucose. It is followed by the binding of insulin to the cells of muscle and fat cells, thereby inhibiting glucose release from the liver. Thus, together Mixtard 30 Flexpen 100 IU Injection 3 ml helps to decrease blood glucose levels after the intake of meals. Besides this, it also prevents the chances of developing serious complications of diabetes, like damage to the retina (retinopathy), damage to the kidney (nephropathy), damage of nerve cells (neuropathy), diabetic foot ulcer, and others.
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Alcohol

Unsafe

You are recommended not to consume alcohol along with Mixtard 30 Flexpen 100 IU Injection 3 ml to avoid unpleasant side-effects. Alcohol may intensify and prolong the hypoglycemic effect of insulin.

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Pregnancy

Consult your doctor

Please inform your doctor if you are pregnant as a dose adjustment may be required. The amount of insulin you need usually falls during the first three months of pregnancy and increases for the remaining six months

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Breast Feeding

Consult your doctor

Please inform your doctor if you are breastfeeding, as a dose adjustment may be required. You may be advised to alter your insulin intake or to modify your diet.

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Driving

Caution

Drive with caution, Mixtard 30 Flexpen 100 IU Injection 3 ml usually causes drowsiness and affects driving ability. Your ability to concentrate and react may be reduced if you have hypoglycemia (low blood sugar).

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Liver

Caution

Mixtard 30 Flexpen 100 IU Injection 3 ml to be taken with caution, especially if you have a history of liver diseases/conditions.

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Kidney

Caution

Mixtard 30 Flexpen 100 IU Injection 3 ml to be taken with caution, especially if you have a history of kidney diseases/conditions. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Mixtard 30 Flexpen 100 IU Injection 3 ml can be given safely to children provided the dose has been prescribed by a child specialist.

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Heart

Caution

Mixtard 30 Flexpen 100 IU Injection 3 ml should be administered with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Mixtard 30 Flexpen 100 IU Injection 3 ml.

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Geriatrics

Caution

Mixtard 30 Flexpen 100 IU Injection 3 ml should be administered with caution in elderly patients. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Mixtard 30 Flexpen 100 IU Injection 3 ml

Do not take more than the prescribed dose of Mixtard 30 Flexpen 100 IU Injection 3 ml as it may cause serious side effects. If you suspect you have taken an overdose, please consult a doctor immediately.

Diet & Lifestyle Advise

  • Exercise may lower your body’s need for insulin during and for some time after the physical activity.
  • Exercise may also speed up the effect of an insulin dose, especially if the exercise involves the area of the injection site (for example, the leg should not be used for injection just prior to running).
  • Avoid eating sugar food and prefer food cooked food low in calories.
  • While traveling across more than 2 time zones, you should talk to your doctor concerning adjustments in your insulin schedule.

Have a query?

How Soon It Starts Working

  • The time required for Mixtard 30 Flexpen 100 IU Injection 3 ml to start to work: The time required for Mixtard 30 Flexpen 100 IU Injection 3 ml to show its action is unknown. 
  • The time for which the effects of Mixtard 30 Flexpen 100 IU Injection 3 ml last: The duration of action for Mixtard 30 Flexpen 100 IU Injection 3 ml is unknown.

What if you forget to take Mixtard 30 Flexpen 100 IU Injection 3 ml

If you miss a dose of Mixtard 30 Flexpen 100 IU Injection 3 ml, consult your doctor for guidance on what to do next. Do not administer the missed dose without doctor's advice.

Storage

• Store in a cool and dry place away from sunlight.• Keep Mixtard 30 Flexpen 100 IU Injection 3 ml out of the sight and reach of children.• Cold chain - To be stored in cold places at 2ºC to 8ºC.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Mixtard 30 Flexpen 100 IU Injection 3 ml is for subcutaneous use only and should never be administered intravenously (IV) or in the veins.
  • If you are changing the brand of insulin, it should be done under strict medical supervision.
  • Cases of heart failure have been reported when pioglitazone was used with insulin especially in patients who are at high risk of cardiac heart failure.
  • The first symptoms of hyperglycemia (high blood sugar level) may include symptoms like excessive thirst, dry mouth, increased frequency of urination, nausea, vomiting, drowsiness, flushed dry skin, loss of appetite, and acetone odor of the breath. You should closely monitor these symptoms.
  • Symptoms like heart failure, weight gain, and edema (fluid deposition in tissue) should not be overruled. You are recommended not to consume alcohol as it may elevate blood glucose levels.
  • Care should be taken when you are traveling across more than 2 time zones.
  • Your doctor may adjust your insulin schedule.
  • Mixtard 30 Flexpen 100 IU Injection 3 ml may decrease the level of potassium leading to a state of hypokalemia that, if left untreated, may lead to respiratory paralysis, irregular heartbeat rhythm, coma, and even death.
  • Do not take this medicine if you have any low blood glucose levels, kidney, liver, or heart problems, or problems with alcohol or other prescription recreational drugs.
  • Mixtard 30 Flexpen 100 IU Injection 3 ml is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius, or else its efficiency may be lost. Do not store it in the freezer of the refrigerator.
  • In type 1 diabetes, untreated high blood sugar levels can lead to a life-threatening condition known as diabetic ketoacidosis.
  • Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause withdrawal symptoms.

Drug-Drug Interactions

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Drug-Drug Interaction: This medicine may have an interaction with anti-depressants (phenelzine, iproniazid, isocarboxazid, nialamide, imipramine, desipramine, tranylcypromine, moclobemide), anti-Parkinson’s drug (selegiline), antibiotic (linezolid), (lithium, tryptophan), migraines drug (sumatriptan), pain killer (tramadol), anti-ulcer (cimetidine, lansoprazole, omeprazole), anti-fungal (fluconazole), anti-stroke pills (ticlopidine), blood-thinners (warfarin, dipyridamole, and phenprocoumon), antimalarial (mefloquine), heart-related drug (flecainide, propafenone), and medicines that decrease blood levels of potassium or magnesium, as these increase the risk of life-threatening heart rhythm disorder. Besides this, the use of oral antidiabetic pills like pramlintide acetate and antibiotics (pentamidine) may cause hypoglycemia (low blood sugar level).

Drug-Food Interaction: Mixtard 30 Flexpen 100 IU Injection 3 ml may interact with an ayurvedic, homeopathy, Unani, herbal supplements, or OTC items. Tell your doctor if you are using these products. Try to avoid intake of alcoholic beverages with Mixtard 30 Flexpen 100 IU Injection 3 ml as it may lower blood sugar level (hypoglycemia).

Drug-Disease Interaction: Mixtard 30 Flexpen 100 IU Injection 3 ml should not be given to patients with kidney disease, liver disease, low potassium level (hypokalaemia), and low blood sugar/glucose level (hypoglycemia).

Isophane Insulin + INSULIN HUMANGatifloxacin
Critical
Isophane Insulin + INSULIN HUMANCinoxacin
Severe

Drug-Drug Interactions

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Isophane Insulin + INSULIN HUMANGatifloxacin
Critical
How does the drug interact with Mixtard-30 Flexpen 100iu Prefilled Pen 3ml:
Coadministration of gatifloxacin with isophane insulin and insulin in human may affect blood glucose levels. Both low blood glucose and, high blood glucose levels.

How to manage the interaction:
Although there is an interaction between isophane insulin and insulin human and gatifloxacin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience nervousness, confusion, headache, dizziness, sleepiness, nausea, hunger, weakness, increased urination, increased thirst, and increased hunger. Do not discontinue any medications without consulting a doctor.
Isophane Insulin + INSULIN HUMANCinoxacin
Severe
How does the drug interact with Mixtard-30 Flexpen 100iu Prefilled Pen 3ml:
Taking isophane insulin and insulin human with cinoxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).

How to manage the interaction:
Although there is an interaction between isophane insulin and insulin human and cinoxacin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience headache, dizziness, drowsiness, nervousness, confusion, shaking, nausea, weakness, sweating, increased thirst, increased hunger, and increased urination. Do not discontinue any medications without consulting a doctor.
Isophane Insulin + INSULIN HUMANCiprofloxacin
Severe
How does the drug interact with Mixtard-30 Flexpen 100iu Prefilled Pen 3ml:
Taking isophane insulin and insulin human with ciprofloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) or hypoglycemia (low blood sugar).

How to manage the interaction:
Although there is an interaction between isophane insulin and insulin human and ciprofloxacin and insulin human, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience headaches, dizziness, sleepiness, nausea, hunger, weakness, increased sweating, and a rapid heartbeat, increased hunger, increased thirst. Do not discontinue any medications without consulting a doctor.
Isophane Insulin + INSULIN HUMANEnoxacin
Severe
How does the drug interact with Mixtard-30 Flexpen 100iu Prefilled Pen 3ml:
Taking isophane insulin and insulin human with enoxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).

How to manage the interaction:
Although there is an interaction between isophane insulin and insulin human and enoxacin they can be taken together if prescribed by a doctor. However, consult a doctor if you experience headaches, dizziness, sleepiness, nervousness, confusion, shaking, nausea, weakness, sweating, increased thirst, increased hunger, and increased urination. Do not discontinue any medications without consulting a doctor.
Isophane Insulin + INSULIN HUMANTrovafloxacin
Severe
How does the drug interact with Mixtard-30 Flexpen 100iu Prefilled Pen 3ml:
Taking isophane insulin and insulin human with trovafloxacin affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).

How to manage the interaction:
Although there is an interaction between isophane insulin and insulin human and trovafloxacin, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, sleepiness, nervousness, confusion, shaking, nausea, weakness, sweating, palpitations, increased thirst, increased hunger, and increased urination. Do not discontinue any medications without consulting a doctor.
Isophane Insulin + INSULIN HUMANNalidixic acid
Severe
How does the drug interact with Mixtard-30 Flexpen 100iu Prefilled Pen 3ml:
Taking isophane insulin and insulin human with nalidixic acid affects blood glucose levels, which may cause hyperglycemia (high blood sugar) and hypoglycemia (low blood sugar).

How to manage the interaction:
Although there is an interaction between isophane insulin and insulin human and nalidixic acid, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience headache, dizziness, sleepiness, nervousness, confusion, shaking, nausea, loss of hunger, weakness, sweating, increased thirst, increased hunger, and increased urination. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Mixtard 30 Flexpen 100 IU Injection 3 ml is used for the treatment of both type 1 and type 2 diabetes mellitus.

Insulin kept out of the refrigerator will not poison you or even make you sick. It just means that your Mixtard 30 Flexpen 100 IU Injection 3 ml will not work as well or deliver its full potential dose. In simple terms, if your blood sugar is high, and you use the insulin that has been kept out, your blood sugar may not be lowered. In short efficacy of Mixtard 30 Flexpen 100 IU Injection 3 ml will be decreased if not kept in the refrigerator between 2-8 degrees Celsius.

If Mixtard 30 Flexpen 100 IU Injection 3 ml is taken in more than the recommended doses, it can cause mild to severe hypoglycemic episodes.

Symptoms of high blood sugar include increased thirst, frequent urination, fatigue, vomiting, shortness of breath, nausea, stomach pain, dry mouth, fruity breath odor, and a fast heartbeat.

Mixtard 30 Flexpen 100 IU Injection 3 ml is to be injected subcutaneously (under the skin). The best areas to give Mixtard 30 Flexpen 100 IU Injection 3 ml are your upper thigh, stomach, upper arm, or buttocks.

Yes, Mixtard 30 Flexpen 100 IU Injection 3 ml is an effective insulin option. It combines Insulin Human and Insulin Isophane, providing both rapid and intermediate-acting insulin effects. This combination helps to control blood sugar levels throughout the day, making it a commonly prescribed treatment for people with diabetes.

It's generally recommended to limit or avoid alcohol consumption while taking Mixtard 30 Flexpen 100 IU Injection 3 ml, as it can interact with insulin and affect blood sugar control. Alcohol can also increase the risk of hypoglycemia (low blood sugar). If you choose to drink alcohol, it's essential to monitor your blood sugar levels closely and consult with your healthcare provider for personalized guidance.

Storage: Store Mixtard 30 Flexpen 100 IU Injection 3 ml in a refrigerator at a temperature between 2°C and 8°C. Do not freeze it. Please keep it away from direct heat and light. Before use, ensure the insulin appears uniformly white and cloudy after resuspension. If it does not, do not use it. Disposal: Dispose of used needles in a puncture-resistant container. Do not reuse needles. Once the Mixtard 30 Flexpen 100 IU Injection 3 ml is empty or no longer needed, dispose of it according to local regulations for medical waste. Do not throw it in household trash.

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Author Details

Veda MaddalaDoctor badge

Written By

  • Veda Maddala

    M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

  • Dr Aneela Siddabathuni

    MPharma., PhD

Last Updated

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi Dl 110034 INDIA
Other Info - MIX0019
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