How does Mipholate-S Tablet 10's work?

Mipholate-S Tablet 10's belongs to the group of medications called immunosuppressants. It works by weakening the immune system by inhibiting the production of cells or antibodies that attack foreign cells. This effect helps in stopping the immune system from targeting and rejecting the transplanted organ.

Does Mipholate-S Tablet 10's increase the chance of infections?

Mipholate-S Tablet 10's causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infection, such as fever, sore throat, breathlessness, jaundice, unexplained bleeding or bruising.

Can the use of Mipholate-S Tablet 10's cause diarrhoea?

Diarrhoea might be a side-effect of Mipholate-S Tablet 10's. Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Does Mipholate-S Tablet 10's cause skin infections?

Mipholate-S Tablet 10's can suppress the immune system and can increase the risk of skin cancer. So, it would be best if you avoid prolonged exposure to sunlight. Also, wear protective clothing covering your head, neck, arms and legs, and use a sunscreen lotion with a high SPF (sun protection factor).

Can I donate blood or sperm while taking Mipholate-S Tablet 10's?

Mipholate-S Tablet 10's can suppress the immune system. You should not donate blood while using Mipholate-S Tablet 10's and for at least 60 days after stopping treatment, as it makes you more prone to infections. Besides, men should not donate sperm while using Mipholate-S Tablet 10's for at least 90 days after stopping the treatment.

Can I take Mipholate-S Tablet 10's with antacids like medicines?

Some medicines might absorb mycophenolate sodium more slowly or faster if taken concomitantly, such as antacids containing aluminium or magnesium, colestipol, cholestyramine, or calcium-free phosphate binders. Before taking Mipholate-S Tablet 10's, speak with your doctor about your ongoing medication list. Your doctor will decide whether they should be taken along with Mipholate-S Tablet 10's.

Can I have vaccinations while on this medication?

The live vaccine may not work while on treatment with Mipholate-S Tablet 10's. Do not have immunisations/vaccinations without talking to your doctor first. Also, avoid contact with people who have recently had immunisations/vaccinations.

How should I take Mipholate-S Tablet 10's?

Mipholate-S Tablet 10's should be swallowed as a whole with water; do not crush or chew it. Mipholate-S Tablet 10's should be taken on an empty stomach (1 hour before or 2 hours after eating or drinking) or as advised by the doctor.

How can I avoid skin-related side effects with Mipholate-S Tablet 10's?

Avoid prolonged or unnecessary exposure to sunlight (sunlamps, tanning beds) and light therapy and wear protective clothing, sunscreen, and sunglasses. This will help lower your risk of developing skin cancer.

Why has my doctor given me Mipholate-S Tablet 10's after I have had a kidney transplant?

Your doctor has prescribed Mipholate-S Tablet 10's to suppress the immunity and prevent the rejection of the transplanted kidney.

Can Mipholate-S Tablet 10's cause cancer?

Mipholate-S Tablet 10's may increase the risk of skin cancer as it reduces the body’s defences. Limit the amount of sunlight and UV light, wear protective clothing and use sunscreen with high SPF.

Is Mipholate-S Tablet 10's a steroid or a chemotherapy drug?

Mipholate-S Tablet 10's is not a steroid or chemotherapy medicine. It is an immunosuppressant used to prevent organ rejection after a transplant.

Can Mipholate-S Tablet 10's cause hair loss?

Mipholate-S Tablet 10's may cause skin problems such as hair loss. Talk to the doctor if you have any concerns.

Do I need any special tests while taking Mipholate-S Tablet 10's?

The doctor may recommend regular blood tests to check for signs of infection and to monitor the blood count. Women of childbearing potential must provide a negative pregnancy test before the start of treatment.

My doctor has asked me to stay away from a person who has chicken pox or shingles. Why?

As Mipholate-S Tablet 10's reduces the body’s defences, you may be at a higher risk of developing infections. Therefore, your doctor has asked you to stay away from a person who has chickenpox or shingles.

What precautions should a female follow while taking Mipholate-S Tablet 10's?

Mipholate-S Tablet 10's causes a high frequency of miscarriage and birth defects. Therefore, before the start of treatment, women of childbearing potential must provide a negative pregnancy test. Also, women who can become pregnant should use effective contraception during treatment and for 6 months after stopping Mipholate-S Tablet 10's. Two forms of contraception are preferable as this will reduce the risk of unintended pregnancy. Contact the doctor about the effective methods of contraception.

What precautions should a male follow while taking Mipholate-S Tablet 10's?

As a precaution, the male or his female partner must use reliable contraception during treatment and for 90 days after stopping Mipholate-S Tablet 10's.

Mipholate-S Tablet 10's

Prescription drug

MRP ₹875

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Written By Santoshini Reddy G , M Pharmacy

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Mipholate-S Tablet 10's is used to prevent organ transplant rejection. It contains Mycophenolate sodium, which works by weakening the immune system and preventing it from rejecting the transplanted organ. In some cases, this medicine may cause side effects such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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About Mipholate-S Tablet 10's

Mipholate-S Tablet 10's is used to prevent the body from rejecting a transplanted organ such as a kidney, heart or liver. Transplant rejection occurs when the recipient’s immune system identifies the transplanted organ as a ‘foreign object’ and attacks it.

Mipholate-S Tablet 10's contains mycophenolate sodium, which works by suppressing the immune system, allowing the transplanted graft to avoid rejection.

In some cases, you may experience certain common side effects, such as diarrhoea, cough, muscle pain, low blood pressure, fever and respiratory infections. Most of these side effects do not require medical attention and will resolve gradually over time. However, talk to your doctor if you experience these side effects persistently.

Do not take Mipholate-S Tablet 10's if you are allergic to any of its ingredients. To avoid recurring symptoms, do not stop it midway. Do not take Mipholate-S Tablet 10's if you are pregnant or planning to become pregnant. Mipholate-S Tablet 10's should not be taken by breastfeeding mothers as it passes into breast milk. Mipholate-S Tablet 10's should not be given to children as safety and efficacy have not been established.

Uses of Mipholate-S Tablet 10's

Mipholate-S Tablet 10's is used to prevent organ rejection in patients who have undergone a kidney, heart, or liver transplant. The detailed uses of Mipholate-S Tablet 10's are as follows:

Prevents organ rejection: Mipholate-S Tablet 10's helps avoid rejection episodes in patients following organ transplantation.
Used with other medications: Mipholate-S Tablet 10's is commonly administered alongside other immunosuppressants to enhance effectiveness.
Maintains graft function: Mipholate-S Tablet 10's supports the long-term survival of the transplanted organ by reducing immune activity.

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Directions for Use

Mipholate-S Tablet 10's should be taken on an empty stomach, at least 1 hour before or 2 hours after eating or drinking.
Follow your doctor's instructions regarding the dosage and duration for effective results.
Swallow Mipholate-S Tablet 10's as a whole with a glass of water.
Do not crush, chew, or break it.

Medicinal Benefits

Mipholate-S Tablet 10's contains Mycophenolate mofetil, an immunosuppressant used primarily in organ transplant recipients.
It helps the body accept transplanted organs (like the kidney, heart, or liver) by suppressing immune responses.
Mipholate-S Tablet 10's inhibits the function of white blood cells (T and B lymphocytes), which are responsible for attacking transplanted organs.
It enhances the long-term success of organ transplantation.
Mipholate-S Tablet 10's is often used along with other immunosuppressants like tacrolimus or cyclosporine for optimal effect.
Preferred over long-term use of corticosteroids due to fewer chronic side effects.

How Mipholate-S Tablet 10's Works

Mipholate-S Tablet 10's contains Mycophenolate sodium used in the treatment of organ transplant rejection, along with another immunosuppressant and anti-inflammatory agent. It inhibits T and B lymphocytes (white blood cells that attack foreign cells) and suppresses antibody production (identifies and kills foreign cells). These effects suppress the immune system so that the transplanted graft is not rejected.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Side effects of Mipholate-S Tablet

High Levels Of Urea In The Blood

Drink more fluids as dehydration can decrease blood flow to kidneys and increase BUN levels.
Eat less protein and stop protein supplements as high protein diet may increase BUN levels.
Severe cases may require kidney transplant or dialysis.

Headache

Dealing with Medication-Induced Headache:

Hydrate your body: Drink enough water to prevent dehydration and headaches.
Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
Take rest: lie down in a quiet, dark environment.
Cold or warm compresses can help reduce tension.
Stay Upright: Maintain good posture to keep symptoms from getting worse.
To treat headaches naturally, try acupuncture or massage therapy.
Over-the-counter pain relievers include acetaminophen and ibuprofen.
Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
Frequent Headaches: If you get reoccurring headaches, consult your doctor.
Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Melanoma

If you observe any new and unusual marks on your skin, discontine the drug and reach out to your doctor for advice.
If the cancer is in the early stage, your doctor may surgically remove the tumour.
Radiation, cancer medications, or targeted treatments may be recommended based on the severity of the cancer.
Consult a dietitian to make sure you are eating the right food and getting enough nutrition during cancer treatment.
Eat your meals in small amounts with a gap of 2-3 hours.
Do light physical activities to relieve tiredness and improve your overall well-being.

Progressive Multifocal Leukoencephalopathy

What if I have taken an overdose of Mipholate-S Tablet 10's

Take Mipholate-S Tablet 10's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include nausea, vomiting, stomach pain, diarrhoea, heartburn, and signs of infection (fever, chills, cough, sore throat). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Mipholate-S Tablet 10's if you are allergic to any immunosuppressant medicines or mycophenolate sodium.
Let your doctor know before using Mipholate-S Tablet 10's if you have liver or kidney problems, severe digestive issues, cancer, liver disease (such as hepatitis B, hepatitis C), current/past infections, or rare genetic disorders (such as Lesch-Nyhan or Kelley-Seegmiller syndromes).
Do not take Mipholate-S Tablet 10's if you are pregnant or planning for pregnancy, as Mipholate-S Tablet 10's is a pregnancy category risk D medicine, which can cause serious congenital disabilities to the unborn baby.
Mipholate-S Tablet 10's should not be taken by breastfeeding mothers, as it passes into breast milk.
Pregnant women should use reliable forms of birth control while on treatment and for six weeks after stopping treatment with Mipholate-S Tablet 10's.
While taking Mipholate-S Tablet 10's, do not contact anyone who has shingles, chickenpox, or measles.
Mipholate-S Tablet 10's causes dizziness and drowsiness, so drive with caution.
Mipholate-S Tablet 10's should not be given to children as safety and efficacy have not been established.
Avoid consuming alcohol along with Mipholate-S Tablet 10's as it could lead to increased dizziness.
Your doctor may advise you to undergo regular blood tests and kidney and liver tests to monitor your condition.
Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using Mipholate-S Tablet 10's.

Drug-Drug Interactions

Mycophenolic acidColestipol

Critical

Mycophenolic acidBaricitinib

Severe

Drug-Drug Interactions

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Mycophenolic acidColestipol

Critical

How does the drug interact with Mipholate-S Tablet:
Coadministration of Colestipol with Mipholate-S Tablet can reduce its absorption and action in the body. This can lead to low treatment results.

How to manage the interaction:
Taking Mipholate-S Tablet with Colestipol is not recommended as it can result in an interaction, it can be taken if your doctor has advised it.

Mycophenolic acidBaricitinib

Severe

How does the drug interact with Mipholate-S Tablet:
Coadministration of Baricitinib and Abatacept can increase the risk of developing serious infections.

How to manage the interaction:
Taking Baricitinib and Abatacept together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.

Mycophenolic acidEthinylestradiol

Severe

How does the drug interact with Mipholate-S Tablet:
Coadministration of Ethinylestradiol with Mipholate-S Tablet may lower the blood levels and effects of Ethinylestradiol, making it less effective as a form of birth control.

How to manage the interaction:
There could be a possible interaction between Mipholate-S Tablet and Ethinylestradiol, but they can be taken together if a doctor has prescribed them. However, if you are taking hormone replacement therapy for menopause, and you notice an increase in the frequency or severity of your symptoms, such as hot flashes, vaginal dryness, or irregular bleeding, consult a doctor. Do not discontinue any medications without a doctor's advice.

Mycophenolic acidTofacitinib

Severe

How does the drug interact with Mipholate-S Tablet:
Coadministration of Mipholate-S Tablet and Tofacitinib can increase the risk or severity of developing serious infections

How to manage the interaction:
Taking Mipholate-S Tablet and Tofacitinib together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.

Mycophenolic acidNafcillin

Severe

How does the drug interact with Mipholate-S Tablet:
Combine use of Nafcillin and Mipholate-S Tablet may reduce the blood levels and effects of Mipholate-S Tablet.

How to manage the interaction:
There could be a possible interaction between Mipholate-S Tablet and Nafcillin, but they can be taken together if your doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhoea, constipation sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, or feet, joint pain, cough, or shortness of breath, consult a doctor. Do not discontinue any medications without a doctor's advice.

Mycophenolic acidCertolizumab

Severe

How does the drug interact with Mipholate-S Tablet:
Taking Mipholate-S Tablet and Certolizumab can lead to or increase the risk of developing serious infections.

How to manage the interaction:
Taking Mipholate-S Tablet and Certolizumab together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, body pain, shortness of breath, or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Mycophenolic acidFerrous sulfate

Severe

How does the drug interact with Mipholate-S Tablet:
Co-administration of Ferrous sulfate with Mipholate-S Tablet decreases levels of Mycophenolate by reducing its absorption.

How to manage the interaction:
There could be a possible interaction between Mipholate-S Tablet and Ferrous sulfate, but they can be taken together if a doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhea, constipation sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, or feet, joint pain, cough, or shortness of breath consult a doctor. Do not discontinue any medications without a doctor's advice.

Mycophenolic acidDesogestrel

Severe

How does the drug interact with Mipholate-S Tablet:
Coadministration of Mipholate-S Tablet and Desogestrel can decrease the levels and action of Desogestrel.

How to manage the interaction:
Co-administration of Desogestrel with Mipholate-S Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms: abnormal menstruation, dryness of the vagina, or increased hot flushes or if you're looking for other birth control options, consult a doctor. Do not discontinue any medications without consulting a doctor.

Mycophenolic acidMedicinal charcoal

Severe

How does the drug interact with Mipholate-S Tablet:
Coadministration of Mipholate-S Tablet and Medicinal charcoal may decrease the levels and effects of Mipholate-S Tablet.

How to manage the interaction:
There could be a possible interaction between Mipholate-S Tablet and charcoal, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms, consult a doctor. Do not discontinue any medications without a doctor's advice.

Mycophenolic acidMedroxyprogesterone

Severe

How does the drug interact with Mipholate-S Tablet:
Coadministration of medroxyprogesterone with Mipholate-S Tablet may decrease the levels and effects of medroxyprogesterone.

How to manage the interaction:
There could be a possible interaction between Mipholate-S Tablet and Medroxyprogesterone, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
Performing yoga may also help improve joint flexibility and pain management.
Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
Get adequate sleep, as resting the muscles can help in reducing inflammation and swelling.
Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
Acupuncture, massage and physical therapy may also be helpful.
Eat food rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
Foods containing flavonoids help in reducing inflammation. These include soy, berries, broccoli, grapes, and green tea.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

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Alcohol

Unsafe

You are recommended to avoid alcohol consumption while taking Mipholate-S Tablet 10's. It could lead to increased dizziness and drowsiness.

Pregnancy

Unsafe

Mipholate-S Tablet 10's may cause birth defects and miscarriage if taken during pregnancy. Follow the contraception advice given by your doctor if you are a woman who could become pregnant. Also, undergo a pregnancy test before starting treatment with Mipholate-S Tablet 10's.

Breast Feeding

Unsafe

It is not recommended to take Mipholate-S Tablet 10's while you are breastfeeding. Mipholate-S Tablet 10's passes into breast milk.

Driving

Unsafe

Mipholate-S Tablet 10's may cause dizziness, tiredness. Do not drive or operate heavy machinery if you feel dizzy.

Liver

Consult your doctor

Consult the doctor if you have liver diseases/conditions, as your doctor may adjust the dose as required.

Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment before taking Mipholate-S Tablet 10's as your doctor may adjust the dose as required.

Children

Unsafe

Mipholate-S Tablet 10's should not be used by children below 18 years of age, as the efficacy and safety have not been established.

FAQs

Country of origin

India

Manufacturer/Marketer address

C/8, Sardar Estate, Ajwa Road, Baroda - 390 019. Gujarat, India.

Other Info - MIP0019

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 26, 2025 | 4:46 PM IST

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