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compositionComposition:ESMOLOL-100MG
prescription
Prescription Medicine
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Miniblock 100mg Injection is used for the short-term treatment of tachycardia (heartbeats too fast). It is also used during and straight after surgery to treat high blood pressure and/or fast heartbeat. It contains Esmolol, which works by controlling the force and rate of heartbeat. It also helps reduce the blood pressure. Thereby, it helps slow down the heart rate and reduce blood pressure. In some cases, Miniblock 100mg Injection may cause side effects such as a fall in blood pressure, excessive sweating, loss of appetite, and headache.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

ESMOLOL-100MG

Manufacturer/Marketer :

USV Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Miniblock 100mg Injection

Receive Miniblock 100mg Injection, an injectable heart medication used by doctors to quickly control rapid heart rate and high blood pressure during critical situations.

Because Miniblock 100mg Injection is given as an intravenous injection or continuous infusion by a healthcare provider, it is typically used for short-term, immediate treatment in a hospital or clinic rather than as a daily home medication. While you receive this treatment, maintaining a quiet environment and avoiding physical stress helps support your recovery. Once your condition stabilises, your doctor may transition you to other long-term lifestyle changes and oral medications.

Some people may experience mild side effects like dizziness, low blood pressure, or mild irritation at the injection site. If you notice severe shortness of breath, a very slow heartbeat, or skin colour changes near the injection area, you must inform your healthcare provider immediately. Your medical team will continuously monitor your vital signs to ensure your safety during treatment.

Do not receive this medicine if you have certain heart conditions, such as a very slow heart rate, heart block, severe heart failure, or a history of severe asthma. Before receiving this medicine, tell your doctor if you have kidney problems, diabetes, or thyroid issues so they can take extra precautions.

This medicine can interact with other blood pressure-lowering drugs or heart medications, which may cause your heart rate or blood pressure to drop too low. If you are pregnant, breastfeeding, or elderly, talk to your doctor or pharmacist to discuss the risks and benefits of receiving this treatment.

Uses of Miniblock 100mg Injection

Miniblock 100mg Injection is used to quickly control rapid heart rate and high blood pressure during critical situations. The detailed uses of Miniblock 100mg Injection are as follows:

  • Rapid heart rate control: Miniblock 100mg Injection helps slow down an abnormally fast heart rate, especially in conditions like atrial fibrillation or atrial flutter, to ease the strain on your heart.
  • High blood pressure during surgery: Miniblock 100mg Injection helps control sudden spikes in blood pressure and heart rate during or immediately after a surgical procedure.
  • Supraventricular tachycardia: Miniblock 100mg Injection helps restore a normal, steady rhythm to your heart when it beats dangerously fast in the upper chambers.

Key Benefits

Miniblock 100mg Injection provides rapid control of heart rate and blood pressure in emergency and hospital settings through intravenous administration. Under close medical supervision, it helps stabilize the heart, reduce cardiovascular strain, and support safer management of acute cardiac conditions.

  • Provides Fast-Acting Control: Because this medicine is administered directly into the bloodstream, it begins working within minutes to quickly lower a dangerously high heart rate or blood pressure when immediate treatment is required.
  • Allows Precise Dose Adjustment: This medicine has a very short duration of action, allowing healthcare professionals to adjust or stop treatment quickly based on your body's changing needs for safe and accurate control.
  • Protects the Heart: By reducing the heart's workload and oxygen demand, this medicine helps stabilise heart function and lowers the risk of further cardiovascular complications during acute medical events or procedures.

Directions for Use

  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Miniblock 100mg Injection will be administered by a nurse or doctor.
  • Do not self-administer.

How Miniblock 100mg Injection Works

Miniblock 100mg Injection contains esmolol, which belongs to a class of medicines called beta-blockers. It works by blocking the action of certain natural chemical messengers in your body, such as adrenaline, on your heart. By blocking these signals, the medicine slows down your heart rate and reduces the force with which your heart muscle contracts. This action lowers your blood pressure and decreases the overall strain on your cardiovascular system, helping your heart pump blood more efficiently.
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Alcohol

Consult your doctor

Taking alcohol with esmolol may have additive effects in lowering blood pressure. Therefore, avoid or limit the consumption of alcohol.

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Pregnancy

Unsafe

The use of Miniblock 100mg Injection is not recommended during pregnancy.

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Breast Feeding

Unsafe

Esmolol may pass into breast milk. Miniblock 100mg Injection is not recommended if you are breastfeeding.

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Driving

Consult your doctor

It is not known if Miniblock 100mg Injection affects your ability to drive. Drive or operate heavy machinery only if you are alert.

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Liver

Consult your doctor

If you have liver disease, inform the doctor before receiving Miniblock 100mg Injection.

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Kidney

Caution

Caution is advised in patients with kidney problems. If you have kidney problems, inform the doctor before receiving Miniblock 100mg Injection.

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Children

Unsafe

Miniblock 100mg Injection is not recommended for children below 18 years as safety and effectiveness have not been established.

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Heart

Consult your doctor

Please consult your doctor before receiving Miniblock 100mg Injection if you have pre-existing heart problems. Your doctor will prescribe Miniblock 100mg Injection if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Miniblock 100mg Injection to geriatric patients. Your doctor will prescribe Miniblock 100mg Injection if the benefits outweigh the risks.

What if I have taken an overdose of Miniblock 100mg Injection

An overdose is rare because healthcare professionals closely monitor your vital signs during treatment. However, if an overdose occurs, the infusion will be stopped immediately, and medical staff will provide supportive care to manage your heart rate and blood pressure.

Diet & Lifestyle Advise

  • Reduce sodium (salt) intake to help maintain healthy blood pressure levels after your treatment.
  • Avoid stimulants such as caffeine, energy drinks, and nicotine, as they can cause rapid or irregular heartbeats.
  • Eat a heart-healthy diet rich in leafy green vegetables, whole grains, and lean proteins.
  • Practice gentle stress-reduction techniques, like deep breathing or meditation, to keep your heart rate stable.
  • If recovering from surgery, follow your healthcare team's specific guidelines regarding physical activity and rest.
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How Soon It Starts Working

The time required for Miniblock 100mg Injection to start to work: Miniblock 100mg Injection ideally shows its action within 2 to 10 minutes after administration. The time for which the effects of Miniblock 100mg Injection last: The effect of Miniblock 100mg Injection lasts for 10 to 30 minutes.

What if you forget to take Miniblock 100mg Injection

Because this medicine is given under direct medical supervision in a hospital setting, it is highly unlikely that you will miss a dose.

Storage

•In clinical settings, Miniblock 100mg Injection should be stored at controlled room temperature, between 15°C and 30°C (59°F and 86°F).

Drug Warnings

  • Always inspect the solution container before use; it should be clear and colourless to light yellow with no visible particles.
  • Tell your doctor immediately if you feel a burning sensation, pain, or swelling around the injection needle.
  • Ensure your blood pressure and heart rate are continuously monitored using an ECG machine during the infusion.
  • Avoid driving or operating heavy machinery immediately after receiving this medication, as it can make you feel dizzy or lightheaded.
  • Inform your medical team of all other medications you are taking, especially other heart medicines, before the injection starts.

verifiedApollotooltip
  • Calcium channel blockers (like verapamil or diltiazem): May cause a dangerously slow heart rate or severe low blood pressure when combined with Miniblock 100mg Injection.
  • Digoxin: May increase the risk of an excessively slow heartbeat.
  • Other blood pressure medicines: May increase the risk of low blood pressure when used together.

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verifiedApollotooltip
  • No clinically significant food interactions are known with Miniblock 100mg Injection when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MISCELLANEOUS]

FAQs

Miniblock 100mg Injection is used to treat Fast heartbeat and high blood pressure.
Miniblock 100mg Injection works by controlling the force and rate of heartbeat. It also helps reduce the blood pressure.
Consult the doctor if you have diabetes, as Miniblock 100mg Injection may mask the symptoms of low blood sugar or increase the effects of diabetic medicines. Regular monitoring of blood glucose levels is advised.
You could develop hyperkalemia (high blood potassium levels), which might lead to serious heart problems if you have kidney disease or need kidney dialysis. Therefore, consult the doctor if you have kidney problems.
You should not receive Miniblock 100mg Injection within 48 hours of stopping verapamil. Consult the doctor if you have any concerns.
Miniblock 100mg Injection does not cause weight gain, as it is typically used for short durations in an acute setting. If you notice unexpected weight changes while using Miniblock 100mg Injection, please consult your doctor to determine whether it is related to the medication or other factors.
It is recommended to follow a low-salt, low-fat diet to reduce strain on your heart. Include plenty of whole grains, vegetables, and fruits in your meals, as they are rich in essential vitamins, minerals, and fibre, which promote optimal health. It is best to avoid high-sodium foods, excessive caffeine, alcohol, and high-fat or fried foods.
While taking Miniblock 100mg Injection, please follow your doctor's advice regarding physical activity. Miniblock 100mg Injection can lower your heart rate and blood pressure, so you should avoid activities that could strain your heart, such as intense exercise or sports. Your doctor may recommend limiting physical exertion or suggest alternative, low-intensity sports. Be sure to monitor your heart rate and any symptoms during exercise while on Miniblock 100mg Injection.
Miniblock 100mg Injection may cause common side effects such as a fall in blood pressure, excessive sweating, loss of appetite, and headache. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
Miniblock 100mg Injection is used to quickly control a rapid heart rate or high blood pressure in emergency situations, acute cardiac events, or during surgical procedures. Talk to your doctor for more details about your specific treatment.
If you have severe asthma or a history of breathing problems, you should not receive Miniblock 100mg Injection, as it can cause airway tightening. Talk to your doctor to find a safer alternative.
Yes, dizziness is a common side effect of Miniblock 100mg Injection because it lowers your blood pressure and heart rate. Your medical team will monitor you closely to manage this. Talk to your doctor if you feel very lightheaded.
No, Miniblock 100mg Injection is only administered by trained healthcare professionals in a hospital or clinical setting where your heart and blood pressure can be continuously monitored. Talk to your doctor for more information.
Miniblock 100mg Injection is generally only used during pregnancy if the potential benefit justifies the risk to the baby, as it can affect the baby's heart rate. Talk to your doctor to evaluate your options.
If you feel burning, pain, swelling, or redness where the IV line is placed, tell your nurse or doctor immediately so they can check the infusion site. Talk to your doctor if you experience any discomfort.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.3561 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.3057 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Drugs.com Clinical Review Team. Esmolol Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  4. Esmolol hydrochloride. 2007. [Accessed on 18 Mar. 2019]Check here
  5. Drugs and Lactation Database (LactMed) [Internet]. 2006. [Accessed on 19 Feb. 2020]Check here
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed on 18 Mar. 2019]Check here
  7. Health Products Regulatory Authority (HPRA). D8E52E0D Dff6 4983 926F F317F3D5C38C Human Medicine Product Information. Dublin, Ireland: HPRA; 2024. [Accessed on 02 Jun. 2026]Check here

Country of origin

India

Manufacturer/Marketer address

112 M, Arcade Mahanir Nagar, Sarawali,Mumbai 401501
Other Info - MI82859
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