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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Migrid Crono-500Mg Cr Tablet is used to treat epilepsy/seizures/fits. Additionally, it is also used to treat mood disorders and migraine. It contains Sodium valproate and Valproic acid, which works by decreasing the excessive and abnormal nerve activity in the brain. Thereby, it helps in controlling seizures. It blocks the nerve transmission across the brain and provides a calming effect. In some cases, it may cause common side effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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Manufacturer/Marketer :

Searle India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Migrid Crono-500Mg Cr Tablet

Migrid Crono-500Mg Cr Tablet belongs to a group of medicines called 'anticonvulsants' or 'anti-epileptics' primarily used to treat epilepsy/seizures/fits. Additionally, Migrid Crono-500Mg Cr Tablet is also used to treat mood disorders and migraine. Epilepsy is a sudden rush of electricity in the brain. In patients with seizures, the typical brain electrical pattern is disrupted by sudden bursts of electrical impulses that affect an individual's consciousness, movements or sensations.
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Migrid Crono-500Mg Cr Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Migrid Crono-500Mg Cr Tablet works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Migrid Crono-500Mg Cr Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.
 
You are advised to take Migrid Crono-500Mg Cr Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as headache, sleepiness, drowsiness, impaired coordination, apathy (lack of interest), irregular periods and weight gain. Talk to your doctor if you experience these side effects persistently.
 
Do not take Migrid Crono-500Mg Cr Tablet if you are pregnant, as it could cause serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Migrid Crono-500Mg Cr Tablet . Consult your doctor before taking Migrid Crono-500Mg Cr Tablet if you are breastfeeding. Migrid Crono-500Mg Cr Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Migrid Crono-500Mg Cr Tablet as it could lead to an increased risk of seizures. Care should be taken while giving Migrid Crono-500Mg Cr Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Uses of Migrid Crono-500Mg Cr Tablet

Treatment of Epilepsy, Mood disorder, Migraine.

Directions for Use

• Take Migrid Crono-500Mg Cr Tablet with food to avoid stomach upset or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Migrid Crono-500Mg Cr Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Migrid Crono-500Mg Cr Tablet is used to treat epilepsy/seizures/fits, mood disorders and to prevent migraine headaches. Migrid Crono-500Mg Cr Tablet decreases the excessive and abnormal nerve activity in the brain, thereby controlling seizures. Migrid Crono-500Mg Cr Tablet is used to treat certain forms of epilepsy, such as petit mal epilepsy (short-term unconsciousness due to a disorder in the brain), myoclonic seizures (sudden muscle contractions) and grand mal epilepsy (severe muscle contractions which lead to unconsciousness). Migrid Crono-500Mg Cr Tablet may also be used to treat epilepsy, which does not sufficiently respond to other anticonvulsant drugs, such as epilepsy, which is not associated with movements and epilepsy, with symptoms affecting perception and deliberate movements. Migrid Crono-500Mg Cr Tablet is used to treat both partial seizures (affects only a part of the brain) and generalised seizures (affects the entire brain).

How Migrid Crono-500Mg Cr Tablet Works

Migrid Crono-500Mg Cr Tablet is a combination of two drugs, namely: Sodium valproate and Valproic acid. Migrid Crono-500Mg Cr Tablet works by decreasing the excessive and abnormal nerve activity in the brain. Thereby helps in controlling seizures. Migrid Crono-500Mg Cr Tablet increases the amount of a chemical substance called GABA, this helps block the nerve transmission across the brain and provides a calming effect.

Storage

Keep Migrid Crono-500Mg Cr Tablet out of reach and sight of children.
Side effects of Migrid Crono-500Mg Cr Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
  • Get plenty of rest and sleep.
  • Keep your body warm.
  • Drink plenty of fluids to stay hydrated.
  • Avoid strenuous activities.
  • Maintain good hygiene to prevent flu from spreading.
  • Eat a balanced diet high in nutrients and low in sugar.
  • Include fruits, vegetables, and leafy greens rich in vitamins C and K.
  • Brush and floss regularly twice a day with fluoride toothpaste and once a day with floss.
  • Use a soft or extra-soft toothbrush.
  • Reduce stress to minimize inflammation and gum bleeding.
  • Avoid tobacco products as smoking can worsen gum disease.
  • Stay hydrated by drinking water to flush bacteria and food particles.
  • Consider vitamin supplements if deficient to support gum health.
  • Use an antimicrobial mouthwash to reduce bacteria and prevent bleeding.
  • Swish with coconut oil for its antibacterial properties to reduce plaque.
  • Drink green tea rich in catechin to reduce inflammation from oral bacteria.
  • Consult your dentist if gums bleed consistently.
  • Apply a cold compress to the affected area for 10 to 15 minutes multiple times a day.
  • Elevate your head while resting or sleeping to reduce fluid accumulation.
  • Drink lots of water to eliminate excess fluids.
  • Limit salty foods as they can cause water retention.
  • To stimulate lymphatic drainage, gently massage the swollen area.

What if I have taken an overdose of Migrid Crono-500Mg Cr Tablet

Do not take more than the prescribed dose of Migrid Crono-500Mg Cr Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Migrid Crono-500Mg Cr Tablet if you are allergic to any of its contents, if you have/ had liver problems, porphyria (blood disorder) or if you are susceptible to bleeding. Inform your doctor if you have inflammation-like diseases, bone marrow damage or kidney problems. Talk to your doctor if you experience weakness, loss of appetite, lack of interest, recurrence or worsening of seizures, prolonged bleeding or abdominal pain while taking Migrid Crono-500Mg Cr Tablet . Consult your doctor immediately if you experience suicidal tendencies while taking Migrid Crono-500Mg Cr Tablet . Please do not stop taking Migrid Crono-500Mg Cr Tablet without consulting your doctor to avoid the worsening of seizures. Do not take Migrid Crono-500Mg Cr Tablet if you are pregnant, as it could cause serious birth defects. If you are of child-bearing age, use effective contraception while taking Migrid Crono-500Mg Cr Tablet . Consult your doctor before taking Migrid Crono-500Mg Cr Tablet if you are breastfeeding. Migrid Crono-500Mg Cr Tablet causes drowsiness and dizziness, so avoid driving unless you are alert. Avoid consuming alcohol along with Migrid Crono-500Mg Cr Tablet as it could lead to increased risk of seizures. Care should be taken while giving Migrid Crono-500Mg Cr Tablet to children below 3 years as there is a higher risk of liver intoxication during the first 6 months of treatment.

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical

Drug-Drug Interactions

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Sodium ValproateSodium phenylbutyrate
Critical
How does the drug interact with Migrid Crono-500Mg Cr Tablet:
Combining Sodium phenylbutyrate and Migrid Crono-500Mg Cr Tablet can increase ammonia levels in the blood.

How to manage the interaction:
Taking Sodium phenylbutyrate with Migrid Crono-500Mg Cr Tablet is not recommended, but it can be taken if prescribed by a doctor. If you experience any symptoms like sudden dizziness, lightheadedness, fainting, headache, shortness of breath, nausea, vomiting, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Migrid Crono-500Mg Cr Tablet:
The combined use of Ertapenem and Migrid Crono-500Mg Cr Tablet can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Ertapenem and Migrid Crono-500Mg Cr Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like loss of seizure control or changes in behavior, consult your doctor immediately. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Migrid Crono-500Mg Cr Tablet:
Co-administration of Ketamine and Migrid Crono-500Mg Cr Tablet can increase side effects and cause respiratory depression.

How to manage the interaction:
Co-administration of Ketamine and Migrid Crono-500Mg Cr Tablet can lead to an interaction, but it can be taken if your doctor advises. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, difficulty concentrating, excessive sedation, impaired thinking, judgment, and motor coordination. Avoid driving or operating hazardous machinery until you know how these medications affect you. Do not discontinue any medications without consulting the doctor.
How does the drug interact with Migrid Crono-500Mg Cr Tablet:
Co-administration of Teriflunomide and Migrid Crono-500Mg Cr Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Teriflunomide and Migrid Crono-500Mg Cr Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and yellowing of the skin or eyes. Avoid alcohol while taking these medications, and consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Migrid Crono-500Mg Cr Tablet:
Using buprenorphine together with Migrid Crono-500Mg Cr Tablet may increase the risk of severe side effects, including respiratory problems and loss of consciousness.

How to manage the interaction:
Although the administration of buprenorphine alongside Migrid Crono-500Mg Cr Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Migrid Crono-500Mg Cr Tablet:
Co-administration of Vorinostat with Migrid Crono-500Mg Cr Tablet can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Vorinostat and Migrid Crono-500Mg Cr Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult your doctor immediately. Do not discontinue any medications without consulting your doctor.
How does the drug interact with Migrid Crono-500Mg Cr Tablet:
Co-administration of Migrid Crono-500Mg Cr Tablet with doripenem can reduce the blood levels of valproic acid.

How to manage the interaction:
Co-administration of Doripenam and Migrid Crono-500Mg Cr Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, involuntary muscle movements, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Migrid Crono-500Mg Cr Tablet:
Co-administration of Leflunomide and Migrid Crono-500Mg Cr Tablet can increase the risk of causing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Migrid Crono-500Mg Cr Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Migrid Crono-500Mg Cr Tablet:
Co-administration of Lithium with Migrid Crono-500Mg Cr Tablet can increase the risk irregular heart rhythm.

How to manage the interaction:
Co-administration of Lithium and Migrid Crono-500Mg Cr Tablet can lead to an interaction, but it can be taken if advised by your doctor. However, consult your doctor immediately if you experience any symptoms like dizziness, drowsiness, confusion, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, and difficulty concentrating. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Migrid Crono-500Mg Cr Tablet:
Co-administration of Meropenam and Migrid Crono-500Mg Cr Tablet together can reduce the effect of Migrid Crono-500Mg Cr Tablet.

How to manage the interaction:
Co-administration of Meropenam and Migrid Crono-500Mg Cr Tablet can lead to an interaction, but it can be taken if your doctor advises. However, if you experience any unusual symptoms, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps in utilising fat instead of glucose for the generation of energy.

  • Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.

  • Exercising regularly helps in maintaining weight and improving overall health. 

  • Rest well, and get plenty of sleep.

  • Avoid smoking and alcohol consumption.

  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.

  • Have a seizure response plan; this helps those around you know what to do.

  • Prepare your living area; small changes may help in reducing the risk of physical injury during a seizure.

  • Understand what triggers seizures and try reducing or avoiding them.

  • Please pay attention to overall health as it can help in reducing seizure activity.

  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Migrid Crono-500Mg Cr Tablet as it may increase the risk of seizures.

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Pregnancy

Unsafe

Migrid Crono-500Mg Cr Tablet belongs to pregnancy category D. Avoid taking Migrid Crono-500Mg Cr Tablet if you are pregnant unless prescribed by a doctor, as it could lead to serious birth defects.

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Breast Feeding

Caution

Migrid Crono-500Mg Cr Tablet may pass into breastmilk. Consult your doctor before taking Migrid Crono-500Mg Cr Tablet if you are breastfeeding.

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Driving

Unsafe

Migrid Crono-500Mg Cr Tablet causes dizziness, sleepiness and drowsiness. Do not drive or operate machinery unless you are alert.

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Liver

Unsafe

Migrid Crono-500Mg Cr Tablet should not be used if you have liver problems or your family has a history of liver problems. Please consult your doctor if you have any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Migrid Crono-500Mg Cr Tablet can be given to children if prescribed by the doctor. The dose will be adjusted by the doctor depending upon the child's body weight.

Have a query?

FAQs

Migrid Crono-500Mg Cr Tablet is primarily used to treat epilepsy/seizures/fits. It is also used to treat mood disorders and migraine.

Migrid Crono-500Mg Cr Tablet decreases the excessive and abnormal nerve activity in the brain. Migrid Crono-500Mg Cr Tablet increases the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect. Thereby helps in controlling seizures.

Do not discontinue Migrid Crono-500Mg Cr Tablet without consulting your doctor. To treat your condition effectually, continue taking Migrid Crono-500Mg Cr Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Migrid Crono-500Mg Cr Tablet ; your doctor will reduce the dose gradually to avoid worsening of seizures.

Migrid Crono-500Mg Cr Tablet may cause thrombocytopenia (low levels of platelets). This might increase the risk of bleeding and bruising. Be cautious while using sharp objects. Consult your doctor if you notice unexplained bleeding or bruising.

Migrid Crono-500Mg Cr Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a proper diet and exercising regularly.

Migrid Crono-500Mg Cr Tablet may increase the effect of aspirin when taken together. Please consult your doctor before taking Migrid Crono-500Mg Cr Tablet with aspirin to avoid unpleasant side-effects. Migrid Crono-500Mg Cr Tablet and aspirin should not be given together to children below 3 years as it could lead to liver intoxication.

Migrid Crono-500Mg Cr Tablet contains sodium valproate and valproic acid as the active ingredients. It is used for the treatment of all types of epilepsy.

Take Migrid Crono-500Mg Cr Tablet with or after food as advised by your doctor.

You are recommended to avoid consumption of alcohol while taking Migrid Crono-500Mg Cr Tablet as it may increase the risk of seizures.

No, Migrid Crono-500Mg Cr Tablet does not cause addiction. However, it should be taken as per dose and duration prescribed by your doctor. Avoid self-medication as it may have severe unwanted effects.

Migrid Crono-500Mg Cr Tablet does not cure epilepsy, it only prevents the seizures from occurring. Therefore, you may need to continue taking it for years. If you experience any problems while taking Migrid Crono-500Mg Cr Tablet , please consult your doctor.

You are recommended not to stop taking Migrid Crono-500Mg Cr Tablet suddenly as it may increase the chances of recurrence of seizures. Therefore, it should be discontinued gradually. If you feel the need to stop taking Migrid Crono-500Mg Cr Tablet , always consult your doctor.

Yes, Migrid Crono-500Mg Cr Tablet may cause weight gain. To control your weight, you should eat a healthy balanced diet and exercise regularly. If you have any other concerns, consult your doctor.

Yes, Migrid Crono-500Mg Cr Tablet has no influence on the working of birth control pills. However, contraceptives (birth control pills) may interfere with the working of Migrid Crono-500Mg Cr Tablet and seizures may occur. Thus, it is essential to inform your doctor if you are using birth control pills. Your doctor will monitor your response to the treatment and Migrid Crono-500Mg Cr Tablet levels in your blood.

Long term use of Migrid Crono-500Mg Cr Tablet is safe for large number of patients. Rarely, using Migrid Crono-500Mg Cr Tablet for long term may weaken your bones, thereby increasing their chances of breaking easily (osteopenia and osteoporosis). Get regular check-ups done for bone health if you are taking Migrid Crono-500Mg Cr Tablet for a prolonged time.

Migrid Crono-500Mg Cr Tablet may cause change of hair colour, thinning of hair, and even hair loss. If you have any concerns, discuss with your doctor if it is possible to reduce the dose of Migrid Crono-500Mg Cr Tablet . Your hair may regrow after either switching to a different medicine or reducing your dose.

Migrid Crono-500Mg Cr Tablet may cause side effects such as nausea, diarrhoea, hair loss, weight gain, headache and irregular periods. If these side effects persist or worsen, please consult your doctor.

You are recommended to avoid taking Migrid Crono-500Mg Cr Tablet if you have known hypersensitivity to valproic acid, have liver disease, or are pregnant. It should be used with caution in kidney impairment patients.

Migrid Crono-500Mg Cr Tablet overdose can cause serious symptoms such as metabolic acidosis and deep coma. If you suspect you have taken overdose of Migrid Crono-500Mg Cr Tablet , seek medical help immediately.

Country of origin

India

Manufacturer/Marketer address

Plot No-66,Shop No-7,Sector-44A Near Palm Beach Road,Sea Woods,Nerul Navi Mumbai Mh 400706 India
Other Info - MIG0130

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