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Midostar 25mg Softgel Capsule 28's is also used to treat aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), or mast cell leukaemia (MCL). It contains Midostaurin, which works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells. This medicine is not recommended for children as safety and effectiveness have not been established.
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About Midostar 25mg Softgel Capsule 28's
Midostar 25mg Softgel Capsule 28's belongs to the group of medicines called protein kinase inhibitors used to treat acute myeloid leukaemia (AML). It is sometimes, also used to treat aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), or mast cell leukaemia (MCL).
Midostar 25mg Softgel Capsule 28's contains Midostaurin, which works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells.
Midostar 25mg Softgel Capsule 28's may cause certain side effects such as nausea, vomiting, headache, fever, musculoskeletal pain, and upper abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen. Take Midostar 25mg Softgel Capsule 28's as prescribed by your doctor.
Discontinue taking Midostar 25mg Softgel Capsule 28's and inform your physician if you observe any allergic reactions. Inform the doctor about your health condition and medications to rule out any side effects. Do not take Midostar 25mg Softgel Capsule 28's if you are pregnant or breastfeeding. This medicine is not recommended for children as safety and effectiveness have not been established.
Uses of Midostar 25mg Softgel Capsule 28's
Midostar 25mg Softgel Capsule 28's is used in the treatment of Acute myeloid leukaemia (AML), aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), and mast cell leukaemia (MCL). The detailed uses of Midostar 25mg Softgel Capsule 28's are as follows:

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Medicinal Benefits
Midostar 25mg Softgel Capsule 28's belongs to the group of medicines called protein kinase inhibitors used to treat acute myeloid leukaemia (AML) in patients who are FLT3 mutation-positive. It is also used to treat aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), or mast cell leukaemia (MCL). Midostar 25mg Softgel Capsule 28's contains Midostaurin, which works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells.
How Midostar 25mg Softgel Capsule 28's Works
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What if I have taken an overdose of Midostar 25mg Softgel Capsule 28's
Drug Warnings
Do not take Midostar 25mg Softgel Capsule 28's if you are allergic to any of its components, if you are taking medicines used to treat tuberculosis (rifampicin), epilepsy (carbamazepine or phenytoin), prostate cancer (enzalutamide), or herbal products (St. John’s Wort) or if you are pregnant or breastfeeding. Inform the doctor if you have any infections, heart disorders, lung, kidney or liver diseases. Seek immediate medical attention if you experience symptoms of low white blood cell count (fever, sore throat, mouth ulcers), lung problems (fever, chest pain, cough with or without mucous, trouble breathing or shortness of breath), or heart problems (chest pain or discomfort, fainting, dizziness, light-headedness, shortness of breath, blue discolouration of your lips, hands or feet, or swelling of your lower limbs).
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Alcohol
Consult your doctor
It is not known if alcohol affects Midostar 25mg Softgel Capsule 28's. Please consult your doctor.
Pregnancy
Unsafe
Midostar 25mg Softgel Capsule 28's is not recommended during pregnancy as it may harm your unborn baby. Therefore, if you are pregnant or planning for pregnancy, talk to the doctor for advice.
Breast Feeding
Unsafe
Midostar 25mg Softgel Capsule 28's may harm the baby. Avoid breastfeeding during treatment with Midostar 25mg Softgel Capsule 28's and for at least 4 months after stopping the treatment.
Driving
Caution
Midostar 25mg Softgel Capsule 28's may cause dizziness and vertigo. Be cautious while driving or operating machinery.
Liver
Consult your doctor
If you have a pre-existing or a history of liver disease, inform your doctor before receiving Midostar 25mg Softgel Capsule 28's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Kidney
Consult your doctor
If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Midostar 25mg Softgel Capsule 28's. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.
Children
Caution
The safety and effectiveness of Midostar 25mg Softgel Capsule 28's in children below 18 years have not been established.
Heart
Midostar 25mg Softgel Capsule 28's may cause QT prolongation, a heart rhythm condition that can lead to serious complications like fainting or irregular heartbeat. If you have heart problems such as heart failure or a history of arrhythmias, your doctor will need to evaluate the risks and may monitor your heart closely during treatment.
Geriatrics
Caution
Geriatric patients can take Midostar 25mg Softgel Capsule 28's, but doctors usually proceed with caution due to age-related changes in metabolism and organ function. Studies suggest it can be effective and safe in older adults with AML, especially when combined with low-intensity therapies.
Midostar 25mg Softgel Capsule 28's is used to treat Acute myeloid leukaemia (AML), aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated haematological neoplasm (SM-AHN), and mast cell leukaemia (MCL).
Midostar 25mg Softgel Capsule 28's works by blocking the action of kinase enzymes in abnormal cells and stops their division and growth. Thereby, it helps prevent the spread of cancer and mast cells.
If you miss a dose of Midostar 25mg Softgel Capsule 28's, take your next dose at the scheduled time. Avoid taking an extra dose to make up for the missed dose.
Midostar 25mg Softgel Capsule 28's may reduce fertility in men and women. Before starting the treatment, discuss with the doctor if you have any concerns regarding fertility.
Continue taking Midostar 25mg Softgel Capsule 28's even if you feel well. Do not stop taking Midostar 25mg Softgel Capsule 28's without talking to the doctor.
If you vomit after taking Midostar 25mg Softgel Capsule 28's, do take another dose. Continue with your regular dosing schedule and take the next dose at your scheduled time. If nausea or vomiting persists or worsens, consult the doctor.
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