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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Mgraft-S 360 mg Tablet 10's contains Mycophenolic acid, which is used to prevent rejection of a transplanted organ such as a liver, kidney, or heart. It belongs to the class of immunosuppressants that work by decreasing the production of white blood cells in the body, helping the body accept the new organ.

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Manufacturer/Marketer :

Advaith Life Sciences Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mgraft-S 360 mg Tablet 10's

Mgraft-S 360 mg Tablet 10's belongs to a class of drugs called immunosuppressants. These drugs are used to prevent rejection of a transplanted organ such as a liver, kidney, or heart. Organ rejection occurs when a patient’s immune system recognizes the donor organ as foreign and tries to eliminate it. 

Mgraft-S 360 mg Tablet 10's contains Mycophenolic Acid, which decreases the production of white blood cells that usually attack foreign invaders and defend the body against foreign cells and infection. As a result, it prevents organ rejection in transplanted patients and helps the body accept the new organ.

Common side effects of Mgraft-S 360 mg Tablet 10's may include stomach pain, vomiting, diarrhoea, high blood pressure, or swelling of the lower legs, feet, and ankles. Most of these side effects of Mgraft-S 360 mg Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

Please tell your doctor if you are allergic to any foods or medicines. If you are pregnant or a breastfeeding mother, it is advised to inform your doctor before taking Mgraft-S 360 mg Tablet 10's. You or your partner are advised to use effective contraceptive measures before starting treatment with Mgraft-S 360 mg Tablet 10's or for 90 days after treatment with Mgraft-S 360 mg Tablet 10's. Limit or avoid alcohol consumption with Mgraft-S 360 mg Tablet 10's as it may increase the risk of liver damage. Drive only if you are alert after taking Mgraft-S 360 mg Tablet 10's as it may cause drowsiness, confusion, or numbness in a few patients. 

Uses of Mgraft-S 360 mg Tablet 10's

Mgraft-S 360 mg Tablet 10's is used to prevent transplanted organ rejection. The detailed uses of Mgraft-S 360 mg Tablet 10's are as follows:<br/>• Prevent organ rejection: Mgraft-S 360 mg Tablet 10's is primarily used to prevent organ rejection after a kidney transplant.<br/>

Directions for Use

• Mgraft-S 360 mg Tablet 10's is usually taken on an empty stomach, either 1 hour before or 2 hours after eating or drinking.• Mgraft-S 360 mg Tablet 10's is usually taken twice a day, or as prescribed by your doctor.• Measure the prescribed dose using a measuring cup and administer it orally.• Shake the bottle well before each use. Avoid using regular household spoons, as they may not measure the dose correctly.

Medicinal Benefits

Mgraft-S 360 mg Tablet 10's contains Mycophenolic Acid, an immunosuppressant used to prevent organ rejection after a heart, kidney, or liver transplant. Mgraft-S 360 mg Tablet 10's is combined with other medications, such as corticosteroids and immunosuppressants. Mycophenolic Acid inhibits the body's production of white blood cells, which usually attack foreign invaders and protect the body from foreign cells and infection. As a result, it prevents organ rejection in transplanted patients and aids the body's acceptance of the new organ.

How Mgraft-S 360 mg Tablet 10's Works

Mgraft-S 360 mg Tablet 10's contains Mycophenolic Acid, which decreases the production of white blood cells that usually attack foreign invaders and defend the body against foreign cells and infection. As a result, it prevents organ rejection in transplanted patients and helps the body accept the new organ.

Storage

• Store in a cool and dry place away from sunlight.• Keep Mgraft-S 360 mg Tablet 10's out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Mgraft-S 360 mg Tablet
  • Drink more fluids as dehydration can decrease blood flow to kidneys and increase BUN levels.
  • Eat less protein and stop protein supplements as high protein diet may increase BUN levels.
  • Severe cases may require kidney transplant or dialysis.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • If you observe any new and unusual marks on your skin, discontine the drug and reach out to your doctor for advice.
  • If the cancer is in the early stage, your doctor may surgically remove the tumour.
  • Radiation, cancer medications, or targeted treatments may be recommended based on the severity of the cancer.
  • Consult a dietitian to make sure you are eating the right food and getting enough nutrition during cancer treatment.
  • Eat your meals in small amounts with a gap of 2-3 hours.
  • Do light physical activities to relieve tiredness and improve your overall well-being.

Drug Warnings

Please tell your doctor if you are allergic to any foods or medications. If you are pregnant or a breastfeeding mother, it is advised to inform your doctor before taking Mgraft-S 360 mg Tablet 10's. You or your partner are advised to use effective contraceptive measures before starting treatment with Mgraft-S 360 mg Tablet 10's, while taking Mgraft-S 360 mg Tablet 10's and for 90 days after stopping treatment with Mgraft-S 360 mg Tablet 10's. Limit or avoid alcohol consumption with Mgraft-S 360 mg Tablet 10's as it may increase the risk of liver damage. Drive only if you are alert after taking Mgraft-S 360 mg Tablet 10's as it may cause drowsiness, confusion or numbness in some patients. If you are about to get vaccinated, inform your doctor before taking Mgraft-S 360 mg Tablet 10's. Mgraft-S 360 mg Tablet 10's may increase the risk of infections or skin cancer as it lowers the body’s immune defence system. While taking Mgraft-S 360 mg Tablet 10's, you are advised to wear protective clothing and use sunscreen while going out.

Drug-Drug Interactions

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Critical

Drug-Drug Interactions

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Critical
How does the drug interact with Mgraft-S 360 mg Tablet:
Coadministration of Colestipol with Mgraft-S 360 mg Tablet can reduce its absorption and action in the body. This can lead to low treatment results.

How to manage the interaction:
Taking Mgraft-S 360 mg Tablet with Colestipol is not recommended as it can result in an interaction, it can be taken if your doctor has advised it.
How does the drug interact with Mgraft-S 360 mg Tablet:
Coadministration of Baricitinib and Abatacept can increase the risk of developing serious infections.

How to manage the interaction:
Taking Baricitinib and Abatacept together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
Mycophenolic acidEtonogestrel
Severe
How does the drug interact with Mgraft-S 360 mg Tablet:
Combine use of Etonogestrel with Mgraft-S 360 mg Tablet may decrease the serum concentration of Etonogestrel.

How to manage the interaction:
There could be a possible interaction between Mgraft-S 360 mg Tablet and Etonogestrel, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mgraft-S 360 mg Tablet:
Taking Mgraft-S 360 mg Tablet and Adalimumab can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Mgraft-S 360 mg Tablet and Adalimumab together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms of fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, or burning urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Mgraft-S 360 mg Tablet:
Coadministration of medroxyprogesterone with Mgraft-S 360 mg Tablet may decrease the levels and effects of medroxyprogesterone.

How to manage the interaction:
There could be a possible interaction between Mgraft-S 360 mg Tablet and Medroxyprogesterone, but they can be taken together if your doctor has prescribed them. However, if you experience hot flashes, vaginal dryness, or abnormal bleeding consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mgraft-S 360 mg Tablet:
Co-administration of Mgraft-S 360 mg Tablet and Cholestyramine may decrease the effectiveness of Mgraft-S 360 mg Tablet.

How to manage the interaction:
Although there is an interaction between Mgraft-S 360 mg Tablet and Cholestyramine, it can be taken together if your doctor has prescribed them. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Mgraft-S 360 mg Tablet:
Coadministration of Mgraft-S 360 mg Tablet and Colesevelam can decrease the levels and effects of Mgraft-S 360 mg Tablet. This can lead to low treatment outcomes.

How to manage the interaction:
There could be a possible interaction between Mgraft-S 360 mg Tablet and Colesevelam, but they can be taken together if your doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhea, constipation, pain in the stomach area, low blood cell counts, infections, sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mgraft-S 360 mg Tablet:
Coadministration of Mgraft-S 360 mg Tablet and Medicinal charcoal may decrease the levels and effects of Mgraft-S 360 mg Tablet.

How to manage the interaction:
There could be a possible interaction between Mgraft-S 360 mg Tablet and charcoal, but they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms, consult a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Mgraft-S 360 mg Tablet:
Co-administration of Ferrous sulfate with Mgraft-S 360 mg Tablet decreases levels of Mycophenolate by reducing its absorption.

How to manage the interaction:
There could be a possible interaction between Mgraft-S 360 mg Tablet and Ferrous sulfate, but they can be taken together if a doctor has prescribed them. However, if you experience upset stomach, nausea, vomiting, diarrhea, constipation sleep problems, fatigue, headache, painful urination, high blood pressure, or swelling of the lower legs, ankles, or feet, joint pain, cough, or shortness of breath consult a doctor. Do not discontinue any medications without a doctor's advice.
Severe
How does the drug interact with Mgraft-S 360 mg Tablet:
Taking Mgraft-S 360 mg Tablet and Golimumab can lead to or increase the risk or severity of developing serious infections.

How to manage the interaction:
There could be a possible interaction between Mgraft-S 360 mg Tablet and Golimumab, but they can be taken together if your doctor has prescribed them. However, if you experience fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

A healthy diet and lifestyle are essential after organ transplants. It can significantly affect recovery, overall health, and the life of the transplanted organ.

Dietary Considerations

  • Nutrient-rich foods: Focus on fruits, vegetables, whole grains, lean proteins, and healthy fats. These provide essential nutrients for healing and overall health.
  • Protein: Ensure adequate protein intake for tissue repair. Include sources like chicken, fish, beans, lentils, and tofu.
  • Limit processed foods: Minimize processed foods, sugary drinks, and unhealthy fats to avoid weight gain and inflammation.
  • Hydration: Stay well-hydrated by drinking plenty of water.
  • Salt: Monitor salt intake, especially if you have high blood pressure. Consult your doctor for specific recommendations.
  • Avoid certain foods: Depending on your transplant and medications, you may need to avoid specific foods. For example, grapefruit may interact with certain immunosuppressants.

Lifestyle Recommendations

  • Exercise: Under medical guidance, engage in age-appropriate physical activity. Exercise improves strength, endurance, and overall well-being.
  • Medications: Take medications as prescribed and on time to prevent organ rejection.
  • Follow-up: Schedule regular appointments with your transplant team for monitoring and care adjustments.
  • Stress management: Learn healthy coping mechanisms like relaxation techniques or hobbies to manage stress.
  • Avoid harmful substances: Avoid smoking and alcohol, as they can harm your organs and interfere with medications.
  • Vaccinations: Stay up-to-date on recommended vaccinations to protect against infections.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS
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Alcohol

Caution

You are recommended to avoid alcohol consumption while taking Mgraft-S 360 mg Tablet 10's. It could lead to increased dizziness and drowsiness.

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Pregnancy

Unsafe

Mgraft-S 360 mg Tablet 10's may cause birth defects and miscarriage if taken during pregnancy. Follow contraception advice given by your doctor if you are a woman who could become pregnant. Also, undergo a pregnancy test before starting treatment with Mgraft-S 360 mg Tablet 10's.

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Breast Feeding

Unsafe

It is not recommended to take Mgraft-S 360 mg Tablet 10's while you are breastfeeding. Mgraft-S 360 mg Tablet 10's passes into breast milk.

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Driving

Caution

Mgraft-S 360 mg Tablet 10's may cause dizziness and tiredness; do not drive or operate heavy machinery if you feel dizzy.

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Liver

Caution

Please inform your doctor if you have a history of liver diseases or conditions. Your doctor may adjust the dose as needed.

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Kidney

Caution

Please inform your doctor if you have a history of kidney diseases or conditions. Your doctor may adjust the dose as needed.

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Children

Safe if prescribed

Mgraft-S 360 mg Tablet 10's is safe for children if prescribed by a doctor. The dose and duration may vary depending on the age and medical condition.

Have a query?

FAQs

Mgraft-S 360 mg Tablet 10's may increase your risk of developing certain types of cancer. It is essential to talk to your doctor regularly about your risk of cancer and any symptoms you might be experiencing.

Mgraft-S 360 mg Tablet 10's is a common immunosuppressant medication prescribed after a kidney transplant. Its primary purpose is to prevent your body from rejecting the transplanted kidney.

Mgraft-S 360 mg Tablet 10's is neither a steroid nor a chemotherapy medication. It's an immunosuppressant, which means it works by suppressing the immune system to prevent organ rejection. Regarding hair loss, MPA can sometimes cause hair loss as a side effect. However, this is not a common side effect, and hair loss is usually resolved after the medication is stopped or the dosage is adjusted.

While taking mycophenolic acid (MPA), you will likely need to undergo regular tests. These tests help monitor your kidney function, blood cell counts, and overall health.

Immunosuppressants like Mgraft-S 360 mg Tablet 10's are essential for preventing organ rejection, but they can also compromise your immune system, increasing your risk of infections. Viral infections like chickenpox and shingles, caused by the varicella-zoster virus, can pose a significant health threat to individuals with weakened immune systems. If you're exposed to someone with these conditions, seek immediate medical advice. Your doctor may recommend preventive measures, such as antiviral medications, to reduce your risk of complications.

Women taking Mgraft-S 360 mg Tablet 10's should avoid pregnancy, as it can harm the fetus. Effective birth control is crucial. If pregnancy occurs, stop the medication immediately and consult a doctor. Additionally, breastfeeding should be avoided due to the risk of medication passing through breast milk. Regular check-ups, informing healthcare providers, and monitoring for side effects are essential.

Men should be aware of the potential for reduced sperm count and fertility while taking this medication. Discuss this with your doctor if you plan to start a family. It's also important to use effective birth control to prevent pregnancy in your female partner. Regular check-ups and monitoring for side effects are essential. If you have concerns, consult your doctor.

No, you should never stop taking Mgraft-S 360 mg Tablet 10's without consulting your doctor. Sudden discontinuation can lead to organ rejection.

It's essential to consult your doctor before taking any over-the-counter medicines while on Mgraft-S 360 mg Tablet 10's. Some medications may interact with it and affect its effectiveness.

Common side effects of Mgraft-S 360 mg Tablet 10's may include stomach pain, vomiting, diarrhoea, high blood pressure, or swelling of the lower legs, feet, and ankles. Most of these side effects of Mgraft-S 360 mg Tablet 10's do not require medical attention and gradually resolve over time. However, if these side effects persist or worsen, please consult your doctor.

Yes, Mgraft-S 360 mg Tablet 10's can interact with other medications, especially other immunosuppressants, antibiotics, and antifungal agents. Discuss all the medications you are taking with your doctor and seek appropriate advice.

It's generally recommended to avoid excessive alcohol consumption while taking mycophenolic acid, as it can increase the risk of side effects.

If you have other health conditions, such as diabetes or heart disease or any, discuss them with your doctor before starting Mgraft-S 360 mg Tablet 10's. Your doctor will weigh the benefits and potential risks before prescribing Mgraft-S 360 mg Tablet 10's.

Country of origin

India

Manufacturer/Marketer address

A-89, 3rd Floor, Dda Shed, Okhla Industrial Phase-2, New Delhi 110020
Other Info - MGR0007

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