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  3. Metronil Injection 100 ml

Metronil Injection 100 ml, Pack of 1 INJECTION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

Metronil Injection is an antibacterial medication used in the treatment of bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, gynaecological infections, meningitis, and endocarditis. This medicine inhibits the bacterial growth by destroying the DNA of the infection causing bacteria. You may experience common side effcts like nausea, vomiting, diarrhoea, constipation, and injection site reaction.

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Composition :

METRONIDAZOLE-500MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Metronil Injection

Metronil Injection belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). 

Metronil Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thus, Metronil Injection treats bacterial infections.

Metronil Injection will be administered by a healthcare professional; do not self-administer. Some common side effects of Metronil Injection are nausea, vomiting, diarrhoea, constipation, and injection site reaction. These side effects are temporary and may resolve after some time. However, if any of the side effects persist or worsen, contact the doctor.

Let your doctor know if you are allergic to metronidazole. Consult your doctor if you are pregnant, planning to get pregnant, or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metronil Injection as it may cause dizziness and drowsiness. Avoid consumption of alcohol while on treatment with Metronil Injection as it may cause unpleasant side effects.

Uses of Metronil Injection

Metronil Injection used in the treatment of bacterial infections. The detailed uses of Metronil Injection are as follows: <br/>• Treatment of Infections: Metronil Injection effectively treats various infections, including intra-abdominal, skin, gynecologic, septicemia, bone and joint, CNS, respiratory tract, and endocarditis, by eliminating anaerobic bacteria and parasites, stopping their growth, and alleviating symptoms.<br/>• Surgical Prophylaxis: Metronil Injection is used as a surgical prophylaxis to prevent postoperative infections, particularly for surgeries involving the gastrointestinal tract.<br/>• Management of Clostridium Difficile Infection: Metronil Injection is used to manage severe Clostridium difficile infections, especially when oral medication is not possible.<br/>• Amoebic Dysentery Treatment: Metronil Injection is used to treat amoebic dysentery, a severe intestinal infection caused by the Entamoeba histolytica parasite.<br/>• Combination Therapy: Metronil Injection is often used in combination with other antibiotics to treat serious infections, offering a broad spectrum of action and enhancing treatment effectiveness.<br/>

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Metronil Injection will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Metronil Injection belongs to a group of medicines known as anti-bacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, gynecologic, respiratory infections, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves). Metronil Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causes helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thereby, Metronil Injection treats bacterial infections.

How Metronil Injection Works

Metronil Injection contains Metronidazole, which suppresses protein synthesis by interacting with DNA and causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms. Thus, Metronil Injection treats bacterial infections.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Metronil Injection

A health care professional administers Metronil Injection in a hospital setting. Hence, the chances of overdose are less. Symptoms of overdose may include nausea, vomiting, loss of muscle coordination, numbness, pain, burning, or tingling in your hands or feet, and seizures. Your doctor may take necessary measures if an overdose is suspected.

Drug Warnings

Do not take Metronil Injection if you are allergic to any of the components. Consult your doctor if you are pregnant, plan to get pregnant or if you are breastfeeding. Do not operate heavy machinery or drive after taking Metronil Injection as it may cause dizziness and drowsiness. Inform your doctor if you have bone marrow depression/low blood count, kidney impairment, CNS disorder, liver or heart problems, peripheral neuropathy, epilepsy, Crohn's disease (a condition in which the body attacks the lining of the digestive tract), yeast infection, oedema (swelling), or blood disorders.

Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Metronil Injection to restore healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet. This food can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should also be included in the diet.
  • Avoid intake of alcoholic beverages with Metronil Injection as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid Metronil Injection in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Metronil Injection Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

You are recommended not to consume alcohol along with Metronil Injection to avoid unpleasant side effects such as stomach pain, nausea, vomiting, flushing, and headache.

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Pregnancy

Caution

Please consult your doctor. Metronil Injection should be used in pregnant women only if clinically needed, and the benefits outweigh the risks.

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Breast Feeding

Caution

Consult your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Metronil Injection .

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Driving

Caution

Metronil Injection may cause dizziness and drowsiness; thus, avoid operating machinery or driving vehicles unless you are alert.

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Liver

Caution

Metronil Injection to be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your liver condition.

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Kidney

Caution

Metronil Injection to be taken with extreme caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your kidney condition.

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Children

Consult your doctor

Limited information about the use of Metronil Injection in paediatric patients. Please seek medical advice. Your doctor will weigh the benefits and risks before prescribing this medicine to your child.

Have a query?

FAQs

Metronil Injection belongs to a group of medicines known as antibacterial agents used to treat severe bacterial infections of the bone, skin and skin structure, blood, joint, abdomen, central nervous system, respiratory, and gynaecological systems, meningitis (infection of the membranes that surround the brain and spinal cord), and endocarditis (infection of the heart lining and valves).

Metronil Injection suppresses protein synthesis by interacting with DNA, causing helical DNA structure loss and strand breakage. As a result, it induces cell death in susceptible organisms, treating bacterial infections.

Caution should be exercised. Metronil Injection may enhance the anticoagulant activity of warfarin and other oral anticoagulants by extending prothrombin time. Inform your doctor if you are taking such medications.

No. Metronil Injection is an antibacterial medicine that acts only against bacterial infections, not viral infections like the common cold and flu.

Metronil Injection should only be used to treat or prevent infections that have been proven or are strongly suspected to be caused by susceptible anaerobic bacteria.

Extreme caution should be exercised while using Metronil Injection in patients with severe liver damage, blood formation disorder, brain, spinal cord or nervous disease. So, let your doctor know if you have any of these conditions.

Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., Sun House, Cts No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - MET1231

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 18, 2025 | 7:01 AM IST

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Reference

  1. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=d46870f5-e2b1-46bd-8413-4a0a8bcf3175&amp;type=display
  2. https://www.medicines.org.uk/emc/files/pil.13293.pdf
  3. https://www.medicines.org.uk/emc/product/1842/smpc#gref
  4. https://www.nhs.uk/medicines/metronidazole/about-metronidazole/
  5. https://www.drugs.com/drug-interactions/metronidazole-index.html?filter=3

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