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compositionComposition:METRONIDAZOLE-1%W/W
prescription
Prescription Medicine
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Metrohex Gel is used to treat and prevent bacterial and parasitic infections, including blood, brain, bone, lung, stomach lining, pelvic area and genital infections, amoebiasis, gum and teeth infections, infected leg ulcers or pressure sores, stomach ulcers caused by Helicobacter pylori, urinary or genital infections caused by the Trichomonas parasite. Furthermore, it can also be used to treat infections that occur after childbirth or wound infections following surgery. It contains Metronidazole, which stops the growth of infection-causing bacteria or parasites. It may cause common side effects such as nausea, vomiting, upset stomach, loss of appetite, dry mouth, and a metallic taste. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METRONIDAZOLE-1%W/W

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Metrohex Gel

Metrohex Gel is a prescription antibiotic and antiprotozoal medication used to treat a wide variety of bacterial and parasitic infections. It works by stopping the growth of certain bacteria and parasites that cause illness in different parts of the body, such as the digestive tract, reproductive system, and skin. It is only effective against specific types of infections and will not work for viral illnesses like the common cold.

For the best results, you must take this medication consistently at evenly spaced times throughout the day as prescribed by your healthcare provider. You can take this medicine with food or a full glass of milk to help prevent stomach upset. Incorporating simple lifestyle habits, such as staying well-hydrated and resting, can further support your body's natural recovery process.

While taking this medication, you may experience mild temporary symptoms like a metallic taste or nausea. However, if you experience more serious side effects, such as persistent numbness, tingling in your hands or feet, or severe abdominal pain, you should contact your doctor immediately.

Do not take this if you have a known allergy to similar anti-infective medications. It is highly important to talk to your doctor before starting this medicine if you have a history of liver disease, kidney disease, or nervous system disorders.

You must completely avoid alcohol and products containing alcohol during your treatment, as combining them can cause severe sickness, including rapid heart rate, redness, and vomiting. If you are pregnant, breastfeeding, or are an elderly individual, consult your healthcare provider to discuss the specific risks and benefits before beginning therapy.

Uses of Metrohex Gel

Metrohex Gel is used to treat various bacterial and parasitic infections. The uses of Metrohex Gel are as follows: 

  • Bacterial infections: Metrohex Gel helps clear bacterial infections in the abdomen, bones, joints, and respiratory tract.
  • Vaginal infections: It treats bacterial vaginosis by restoring the natural balance of bacteria in the vaginal area.
  • Parasitic infections: It eliminates parasites causing intestinal infections, like amebiasis, or sexually transmitted infections, like trichomoniasis.

Key Benefits

Metrohex Gel helps treat bacterial and parasitic infections by eliminating the organisms responsible for the infection. This helps relieve symptoms and supports faster recovery.

  • Relieves Infection Symptoms: Helps reduce symptoms such as diarrhoea, pelvic pain, abdominal discomfort, and unusual vaginal discharge by treating the underlying infection.
  • Treats Bacterial and Parasitic Infections: Effectively targets and eliminates certain bacteria and parasites responsible for a variety of infections.
  • Promotes Faster Recovery: Helps clear the infection and supports a quicker return to normal daily activities.
  • Prevents Infection Spread: By controlling the infection early, it may help prevent the infection from worsening or spreading to other parts of the body.
Side effects of Metrohex Gel 10 gm
  • Moisturize frequently with thick, broad-spectrum moisturizers containing sunscreen.
  • Use warm water for short baths, and gentle cleansers.
  • Pat dry and apply moisturizer immediately.
  • Use a humidifier to add moisture to the air, and choose breathable fabrics like cotton and silk.
  • Wash clothes with fragrance-free detergents to minimize irritation.
  • After taking a shower or bath, apply a moisturizer to damp skin.
  • Use petroleum jelly or other thick emollients.
  • Use a hypoallergenic, fragrance-free moisturizer 2 to 3 times a day or as frequently as required.
  • Exfoliate your skin gently using a pumice stone or slightly abrasive sponge.
  • Do not scrub your skin.
  • Avoid hot showers or baths. Instead take short, warm showers or baths.
  • Use mild soap or skin cleansers with added moisturizer.
  • Drink lots of water.
  • Use sunscreen and wear protective clothing while going out to protect yourself from sun damage.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Here are the steps to manage medication-triggered Burning Or Stinging:
  • If you experience burning or stinging sensations and suspect that they may be related to medication, consult a doctor or healthcare expert to determine the cause and best course of treatment.
  • Avoid harsh products, extreme temperatures, and other potential irritants that may exacerbate burning or stinging.
  • Your healthcare professional may recommend applying a soothing or protective agent, such as a cream, gel, or ointment, to help alleviate burning or stinging.
  • Follow your healthcare professional's advice on how to care for the affected area, as gentle cleaning and care instructions may vary depending on the location and severity of the burning or stinging.
  • Schedule follow-up appointments with your doctor to monitor your symptoms and adjust your treatment plan as needed. If the burning or irritation persists or worsens, seek medical attention.
  • Clean the affected area with soap and water.
  • Apply a cold compress on the affected area for relief.
  • Avoid scratching the affected area.
  • Inform your doctor about the reaction so they can adjust your treatment plan and suggest alternative medications.
  • Get immediate medical attention if symptoms persist or worsen.
  • Consult a healthcare professional to diagnose the skin infection and receive appropriate treatment.
  • Follow your doctor's instructions for treatments including creams, ointments, or antibiotics to stop the spread of germs.
  • Avoid scratching to help stop further infection and irritation.
  • Particularly after handling the affected region, wash your hands frequently.
  • To stop the spreading of infection, avoid sharing personal items including towels, clothes, and makeup.
  • Keep your skin moist to avoid dryness and irritations.
  • If your symptoms worsen or don't change, let your doctor know as they provide medical attention.
  • Tell your doctor about the excessive oiliness so they can adjust your medication or offer advice.
  • Your doctor may recommend alternative medications with fewer side effects on oil production.
  • Wash your skin twice a day with a gentle cleanser to remove excess oil and dirt.
  • Choose oil-free, non-comedogenic products to prevent clogged pores.
  • Use clay masks to absorb excess oil and cleanse the skin.

Directions for Use

To get the maximum benefit from treatment with Metrohex Gel, follow these instructions carefully: 

  • Swallow the tablet whole with a full glass of water or milk.
  • Do not crush, chew, or break the tablet, as this can affect how the medicine is absorbed and may cause an unpleasant taste.

Always follow your doctor's exact instructions regarding the duration of your treatment. It is vital to complete the entire course of medication, even if your symptoms improve after a few days, to prevent the infection from returning.

How Metrohex Gel Works

The active drug, metronidazole, enters the cells of the invading bacteria or parasites. Once inside, it interacts with the organism's genetic material (DNA) and disrupts its structure. This prevents the bacteria or parasites from multiplying, repairing themselves, or surviving, which quickly stops the infection from spreading and allows your immune system to clear the remaining pathogens.
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Alcohol

Unsafe

You are recommended not to consume alcohol while on treatment with Metrohex Gel and for 48 hours after completing the course to avoid unpleasant side effects such as nausea, vomiting, stomach pain, palpitations, headache, and hot flushes.

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Pregnancy

Unsafe

Metrohex Gel should not be used during pregnancy, especially during the first trimester. Inform your doctor if you are pregnant or planning to become pregnant.

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Breast Feeding

Unsafe

Metrohex Gel may pass into breast milk. Avoid breastfeeding while taking Metrohex Gel and for 12-24 hours after completing the course.

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Driving

Caution

Metrohex Gel may cause dizziness and drowsiness; therefore, avoid driving or operating machinery unless you are alert.

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Liver

Caution

Metrohex Gel should be taken with caution, especially if you have a history of liver diseases/conditions. Your doctor may adjust your dose depending on your liver condition.

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Kidney

Caution

Metrohex Gel should be taken with caution, especially if you have a history of kidney diseases/conditions. Your doctor may adjust your dose depending on your kidney condition.

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Children

Safe if prescribed

Metrohex Gel should be given to children only if prescribed by a doctor. Your doctor may adjust the dose as per the age of your child.

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Heart

Consult your doctor

Please consult your doctor before using Metrohex Gel if you have pre-existing heart problems.

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Geriatrics

Caution

Metrohex Gel should be taken with caution in elderly patients as it can cause age-related problems. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Metrohex Gel

If you suspect an overdose or experience severe symptoms like vomiting, loss of balance, or numbness, seek immediate medical attention or contact a poison control centre right away.

Diet & Lifestyle Advise

  • Avoid Alcohol Completely: Do not consume alcohol, including beer, wine, spirits, or alcohol-containing products such as certain cough syrups, while taking this medicine.
  • Stay Well-Hydrated: Drink plenty of fluids, such as water and clear broths, especially if you are recovering from a digestive tract infection.
  • Choose Simple Foods: Eat bland, easy-to-digest foods if you experience nausea or stomach discomfort after taking your medication.
  • Support Gut Health: Consider taking a probiotic supplement a few hours after your dose to help maintain healthy gut bacteria and support digestive health.
health query

Have a query?

How Soon It Starts Working

The time required for Metrohex Gel to start to work: Metrohex Gel ideally shows its action within 4 hours after administration. The time for which the effects of Metrohex Gel last: The effect of Metrohex Gel lasts for 12 hours.

What if you forget to take Metrohex Gel

Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store the oral tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). • Keep the medication in its original packaging to protect it from direct light, moisture, and extreme heat. Do not store it in the bathroom cabinet.

Drug Warnings

  • Avoid Alcohol After Treatment: Wait at least 72 hours after your final dose before consuming alcohol to help prevent severe nausea, vomiting, flushing, headaches, and other reactions.
  • Use Caution When Driving: Do not drive or operate machinery if you feel dizzy, lightheaded, or confused after taking this medicine.
  • Inform Your Doctor About Blood Thinners: Tell your doctor if you are taking blood-thinning medicines, as Metrohex Gel may increase the risk of bleeding.
  • Watch for Nerve Symptoms: Stop taking the medicine and contact your healthcare provider immediately if you develop tingling, numbness, weakness, or other unusual nerve-related symptoms.

Drug-Drug Interactions

verifiedApollotooltip

Inform your doctor if you are taking any of the following medicines, as they may interact with Metrohex Gel:

  • Blood Thinners: Taking Metrohex Gel with blood thinners such as warfarin may increase the risk of bleeding.
  • Lithium: Metrohex Gel may increase lithium levels in the body and raise the risk of lithium toxicity, including kidney-related complications.
  • Disulfiram: Do not take Metrohex Gel if you have used disulfiram within the previous two weeks, as this combination may cause severe confusion and mental health symptoms.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

The following food and beverage interactions may occur while taking Metrohex Gel: 

  • Alcohol and Propylene Glycol: Consuming alcohol or products containing propylene glycol while taking Metrohex Gel may cause a severe reaction characterised by vomiting, flushing, rapid heartbeat, headaches, and nausea.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIMICROBIALS]

FAQs

Metrohex Gel is used to treat and prevent bacterial and parasitic infections, including blood, brain, bone, lung, stomach lining, pelvic area and genital infections, amoebiasis, gum and teeth infections, infected leg ulcers or pressure sores, stomach ulcers caused by Helicobacter pylori, urinary or genital infections caused by the Trichomonas parasite. Furthermore, it can also be used to treat infections that occur after childbirth or wound infections following surgery.
Metrohex Gel works by preventing the production of proteins required by harmful microorganisms for their survival. Thereby, Metrohex Gel helps treat and prevent bacterial and parasitic infections.
No. Metrohex Gel is an antimicrobial medicine that acts only against bacterial infections, not against viral infections such as the common cold and flu.
If you miss a dose of Metrohex Gel, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and follow your regular schedule. Never take a double dose to make up for the missed one.
Metrohex Gel may cause jaundice in a rare case. Please consult your doctor immediately if you notice yellowing of the skin and eyes.
Metrohex Gel may also be used with other medications to treat certain stomach/intestinal ulcers caused by a bacteria (H. pylori). Even so, it can only be used if advised by a doctor.
Do not take more than the prescribed dose of Metrohex Gel, as it may cause an overdose. The symptoms of an overdose include nausea, vomiting, seizures (fits), loss of muscle coordination, and numbness, burning, pain, or tingling in the hands or feet. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.
If the symptoms do not improve within a few days after starting this medicine or if they worsen, consult your doctor. They will reassess the condition and provide guidance on appropriate treatment.
Metrohex Gel may interact with certain medications. So, do not use any other medications with Metrohex Gel unless recommended by the doctor. Your doctor will check for potential interactions and prescribe you if necessary.
Antibiotics like Metrohex Gel may reduce the vaccine's activity. To ensure an adequate vaccine response, vaccination should be administered at least 14 days after completing treatment with Metrohex Gel or 10 days before starting therapy with Metrohex Gel. Talk to your doctor if you have any questions or concerns.
Let your doctor know about your child’s medical history and ongoing medications before prescribing Metrohex Gel.
Yes, it is normal. Metrohex Gel can cause urine discolouration. This is harmless and should resolve on its own once your child stops taking the medication.
Metrohex Gel may interfere with some drugs. Always check with a doctor before giving any medication, especially if your child is feverish. The doctor will advise the best course of treatment for your child.
To ensure the medication's effectiveness and progress of the medical condition, the doctor may perform certain lab tests, such as a complete blood count (CBC), liver function test (LFT), and kidney function test (KFT) if necessary.
Common side effects of Metrohex Gel may include nausea, vomiting, upset stomach, loss of appetite, dry mouth, and a metallic taste. Most of these side effects do not require medical attention and will gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
No, you must avoid all alcohol during treatment and for at least 3 days after your last dose. Combining the two can cause a severe, unpleasant reaction, including vomiting, rapid heartbeat, and intense headaches. Talk to your doctor if you have concerns about avoiding alcohol.
A metallic taste is a very common and temporary side effect of metronidazole. You can manage this by chewing sugar-free gum, sucking on hard candies, or maintaining good oral hygiene. Talk to your doctor if this symptom becomes too uncomfortable to manage.
You should only take this medicine during pregnancy if it is clearly needed and prescribed by your doctor. Your healthcare provider will weigh the benefits against the risks, especially during the first trimester. Talk to your doctor to discuss your options.
You can take this medication with or without food. However, taking it with a meal or a glass of milk is highly recommended as it helps prevent stomach irritation, nausea, and indigestion. Talk to your doctor or pharmacist if you have persistent stomach discomfort.
The medication begins working against the infection within a few hours of your first dose. However, it may take a few days before you notice a significant improvement in your physical symptoms. Talk to your doctor if your symptoms do not improve or get worse after a few days.
Stopping the medication early can allow the remaining bacteria or parasites to multiply and cause the infection to return, potentially making it resistant to future treatments. Always complete the entire course prescribed by your doctor. Talk to your doctor if you feel you need to stop early due to side effects.
Yes, like many antibiotics, Metrohex Gel can disrupt the natural balance of microorganisms in your body, which may lead to an overgrowth of yeast. This can result in a vaginal yeast infection or oral thrush. Talk to your doctor if you notice unusual discharge, itching, or white patches in your mouth.
Metrohex Gel can sometimes cause urine to appear dark brown or reddish-brown. This is usually harmless and occurs due to breakdown products of the medicine. However, if dark urine occurs together with yellowing of the skin or eyes, severe fatigue, or abdominal pain, seek medical advice promptly. Talk to your doctor if you are concerned.

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Reference

  1. Drugs.com Clinical Review Team. Metronidazole Clinical Drug Monograph. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  2. MedlinePlus. A689011 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  3. DailyMed Database. Lookup.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026]Check here
  4. National Health Service (NHS). About Metronidazole - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  5. Electronic Medicines Compendium (EMC). Pil.5882 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  6. Drugs.com Clinical Review Team. Metronidazole Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  7. Metronidazole Metronidazole. 2013. [Accessed on 29 Mar. 2019]Check here

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Other Info - MET0092
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