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compositionComposition:METRONIDAZOLE-500MG+OFLOXACIN-200MG
prescriptionPrescription Medicine
Metrogyl O Tablet 15's

Metrogyl O Tablet 15's is used to treat various bacterial infections. It is also effective in treating diarrhoea due to mixed infections and dysentery caused by amoebas. It contains Ofloxacin and Metronidazole, which work by killing the bacteria and parasites responsible for the infections. In some cases, you may experience side effects such as nausea, vomiting, stomach upset, loss of appetite, dry mouth, and a metallic taste. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

METRONIDAZOLE-500MG+OFLOXACIN-200MG

Manufacturer/Marketer :

J B Chemicals & Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Metrogyl O Tablet 15's

Metrogyl O Tablet 15's is a combination of antibacterial (ofloxacin) and anti-amoebic (metronidazole) medication used to treat various infections caused by bacteria. It is also effective in treating diarrhoea due to mixed infections and amoebic dysentery. A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our bodies. Diarrhoea is an increase in the frequency of bowel movements, resulting in loose and watery stools. Amoebic dysentery (Also Known as Amoebiasis) is an intestinal infection caused by the parasite Entamoeba histolytica.

Metrogyl O Tablet 15's is a combination of two antibiotics that include Ofloxacin and Metronidazole. Ofloxacin prevents the division of bacterial cells and inhibits their repair mechanism, leading to the death of the bacteria. Metronidazole kills parasites and anaerobic bacteria that cause infections. It works by damaging their DNA. Both antibiotics are bactericidal in nature and work together to effectively treat the infection.

Take Metrogyl O Tablet 15's exactly as prescribed. Your doctor will recommend how often you take Metrogyl O Tablet 15's based on your medical condition. In some cases, you may experience common side effects, including nausea, vomiting, stomach upset, loss of appetite, dry mouth, a metallic taste, headache, dizziness, drowsiness, and confusion. Most of these side effects of Metrogyl O Tablet 15's do not require medical attention and typically resolve on their own over time. However, if the side effects are persistent, reach out to your doctor.

It is not advisable to stop taking Metrogyl O Tablet 15's suddenly to avoid unpleasant side effects. The full course prescribed by the doctor should be completed. Inform your doctor if you have any lung disease, epilepsy, difficulty sleeping (sleep apnoea), severe liver disease, or problems with alcohol or other prescription or recreational drugs. Metrogyl O Tablet 15's should not be used by pregnant women (especially during the first trimester), breastfeeding mothers, and patients with liver diseases, low blood white cells (leukopenia), seizures (fits), gastrointestinal diseases (like Crohn's disease and inflammatory bowel disease), and other neurological diseases. Metrogyl O Tablet 15's may cause dizziness and drowsiness; therefore, avoid driving and operating machinery until you are mentally alert.

Uses of Metrogyl O Tablet 15's

Metrogyl O Tablet 15's is used in the treatment of various bacterial and parasitic infections. Its detailed uses are as follows:

  • Bacterial Infections: Metrogyl O Tablet 15's is effective in treating bacterial infections of the lungs, skin, prostate, urinary tract (kidneys and bladder), and gastrointestinal tract (stomach and intestines).
  • Diarrhoea Due to Mixed Infections: Metrogyl O Tablet 15's is prescribed for the treatment of diarrhoea caused by a combination of bacterial and parasitic organisms, such as those caused by Giardia lamblia (a parasite) and Clostridium difficile (a bacteria).
  • Amoebic Dysentery (Amoebiasis): Metrogyl O Tablet 15's is also effective in treating intestinal amoebiasis caused by Entamoeba histolytica, a parasite that leads to diarrhoea and dysentery.
  • Gynaecological Infections: Metrogyl O Tablet 15's helps in managing pelvic inflammatory disease (caused by sexually transmitted infections like gonorrhoea and chlamydia) and vaginosis (caused by an imbalance of bacteria in the vagina).
  • Post-Surgical Infections: Metrogyl O Tablet 15's may also be used to treat or prevent bacterial infections after certain abdominal or gynaecological surgeries.

Key Benefits

Metrogyl O Tablet 15's is used to treat various bacterial infections affecting the lungs, skin, prostate, urinary tract, and gastrointestinal tract. It is also effective in treating diarrhoea caused by mixed infections (involving both bacteria and parasites) and amoebic dysentery. It is a combination of two antibiotics: Ofloxacin and Metronidazole. Ofloxacin (an antibacterial) prevents the division of bacterial cells and inhibits their repair mechanism, leading to the death of the bacteria. Metronidazole kills parasites and anaerobic bacteria that cause infections. It works by damaging their DNA. Both antibiotics are bactericidal in nature and work together to treat the infection effectively.

Side effects of Metrogyl O Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Wear cotton underwear and loose pants to facilitate better airflow.
  • Try meditation and yoga to reduce stress and improve balance hormones.
  • Eat foods like yogurt or kefir to support vaginal health.
  • Gently clean the genital area with soap and lukewarm water.
  • Avoid fragrant soap, bubble baths, and douches; these can also irritate.
  • Tell your doctor about any medications or supplements you’re taking, as they may affect vaginal discharge treatments.

Directions for Use

  • Metrogyl O Tablet 15's may be taken with or without food (excluding dairy), but taking it with food may lessen stomach discomfort.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Metrogyl O Tablet 15's as a whole with a glass of water.
  • Do not break, crush, or chew it.

How Metrogyl O Tablet 15's Works

Metrogyl O Tablet 15's is a combination of two antibiotics: Ofloxacin and Metronidazole. Ofloxacin works by preventing bacterial cell division and inhibiting their repair mechanisms, ultimately leading to bacterial cell death. Metronidazole is effective against parasites and anaerobic bacteria; it works by damaging their DNA, resulting in their elimination. Both antibiotics are bactericidal in nature and act synergistically to effectively treat a wide range of infections.
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Alcohol

Unsafe

Alcohol should not be consumed while taking Metrogyl O Tablet 15's, as it may increase the risk of side effects like dizziness and drowsiness.

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Pregnancy

Unsafe

Metrogyl O Tablet 15's should not be taken during pregnancy, especially during the first trimester, as it may cause harm to the fetus. If you become pregnant while taking Metrogyl O Tablet 15's, stop taking the medication, and contact your doctor immediately.

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Breast Feeding

Unsafe

Metrogyl O Tablet 15's may pass into the breast milk, so avoid taking Metrogyl O Tablet 15's while breastfeeding.

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Driving

Unsafe

Metrogyl O Tablet 15's can cause dizziness, confusion, and drowsiness. Therefore, avoid driving or operating machinery unless you are mentally alert and competent.

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Liver

Consult your doctor

Metrogyl O Tablet 15's to be taken with caution, especially if you have a history of liver diseases. The dose may have to be adjusted by your doctor.

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Kidney

Consult your doctor

Metrogyl O Tablet 15's to be taken with caution, especially if you have a history of kidney diseases. The dose may have to be adjusted by your doctor.

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Children

Safe if prescribed

Metrogyl O Tablet 15's can be given to the children if prescribed by a doctor.

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Heart

Consult your doctor

Please consult your doctor before using Metrogyl O Tablet 15's if you have pre-existing heart problems.

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Geriatrics

Consult your doctor

Please consult a doctor before giving Metrogyl O Tablet 15's to geriatric patients.

What if I have taken an overdose of Metrogyl O Tablet 15's

Do not take more than the prescribed dose of Metrogyl O Tablet 15's. Taking extra medication will not improve your symptoms and may lead to poisoning or serious side effects. If you suspect an overdose or experience any adverse effects, seek immediate medical attention at the nearest emergency department.

Diet & Lifestyle Advise

  • Avoid consuming excessive amounts of caffeine-containing products, such as coffee, tea, energy drinks, cola, or chocolate. Metrogyl O Tablet 15's may increase nervousness, sleeplessness, and anxiety caused by caffeine.
  • Probiotics should be taken after completing the full course of Metrogyl O Tablet 15's to help restore healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods, such as yoghurt, cheese, sauerkraut, kombucha, and kimchi, can help restore the gut's beneficial bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains, such as whole-grain bread and brown rice, should be included in your diet. Make sure to drink plenty of water or other fluids every day while you are taking Metrogyl O Tablet 15's.
  • Avoid the intake of alcoholic beverages, as they can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the Metrogyl O Tablet 15's in fighting off infections.

Have a query?

How Soon It Starts Working

The time required for Metrogyl O Tablet 15's to start to work: The time required for Metrogyl O Tablet 15's to show its action is unknown. The time for which the effects of Metrogyl O Tablet 15's last: The duration of action for Metrogyl O Tablet 15's is unknown.

What if you forget to take Metrogyl O Tablet 15's

If you miss a dose of Metrogyl O Tablet 15's, take it as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for the missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

If you are allergic to ofloxacin, metronidazole, or any other antibacterial or anti-amoebic agents, please inform your doctor to avoid any unwanted side effects like swallowing or breathing problems, swelling of your lips, face, throat, or tongue. Taking Metrogyl O Tablet 15's may increase the chances of developing tendinitis (swelling of a tissue that joins a bone to a muscle) or a tendon rupture. Dairy products should be avoided along with Metrogyl O Tablet 15's. Additionally, exposure to sunlight should be avoided while taking Metrogyl O Tablet 15's, as it may increase phototoxicity or photosensitivity. Patients with an irregular heartbeat (QT prolongation) should tell their doctor before taking Metrogyl O Tablet 15's. Metrogyl O Tablet 15's should not be given to the pregnant mother (during the first trimester) and in nursing mothers as it passes into the breast milk. Please inform your doctor before taking Metrogyl O Tablet 15's if you have a history of liver disease, low blood white cells (leukopenia), a joint or tendon disorder (such as rheumatoid arthritis), seizures (fits), gastrointestinal diseases (like Crohn's disease and Inflammatory bowel disease), or other neurological diseases. Metrogyl O Tablet 15's may cause dizziness and drowsiness; therefore, avoid driving and operating machinery until you are mentally alert. Avoid alcohol consumption while taking Metrogyl O Tablet 15's, as it may increase the risk of side effects like dizziness and drowsiness.

Drug-Drug Interactions

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Drug-drug interaction: Metrogyl O Tablet 15's may interact with pain killers (ibuprofen or diclofenac), anti-asthma medications (theophylline), anti-diabetic drugs (glibenclamide), anti-gout drugs (probenecid), anti-cancer drugs (5-fluorouracil), antidepressants (lithium), antiepileptics (phenobarbital, phenytoin), and blood thinners (warfarin).

Drug-Food Interaction: Metrogyl O Tablet 15's interacts with dairy products (such as yoghurt) or calcium-fortified juices alone.

Drug-Disease Interaction: Inform your doctor if you have or have ever had a kidney, heart, or lung transplant, kidney disease, low blood white cells (leukopenia), a joint or tendon disorder (rheumatoid arthritis), seizures (fits), and gastrointestinal diseases (like Crohn's disease and Inflammatory bowel disease).

Ofloxacin + MetronidazoleAmprenavir
Critical
Ofloxacin + MetronidazoleAmiodarone
Critical

Drug-Drug Interactions

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Ofloxacin + MetronidazoleAmprenavir
Critical
How does the drug interact with Metrogyl O Tablet:
Co-administration of Amprenavir with Ofloxacin and Metronidazole can increase the risk or severity of side effects.

How to manage the interaction:
Taking Ofloxacin and Metronidazole with Amprenavir is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience throbbing in the head and neck, difficulty breathing, vomiting, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleAmiodarone
Critical
How does the drug interact with Metrogyl O Tablet:
Taking Amiodarone with Ofloxacin and Metronidazole may significantly increase the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Amiodarone with Ofloxacin and Metronidazole interact, it can be taken if prescribed by a doctor. If you get dizziness, or fast or racing heartbeats, consult a doctor. Do not stop taking any medications without consulting a doctor.
Ofloxacin + MetronidazoleCisapride
Critical
How does the drug interact with Metrogyl O Tablet:
Coadministration of Ofloxacin and Metronidazole with Cisapride can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Taking Ofloxacin Metronidazole with Cisapride together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness, shortness of breath, chest pain, rapid heartbeat contact a doctor immediately. Do not discontinue any medications without consulting a doctor. Note: Cisapride is no longer available on the market.
Ofloxacin + MetronidazoleHalofantrine
Critical
How does the drug interact with Metrogyl O Tablet:
Using halofantrine together with ofloxacin and Metronidazole can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ofloxacin and Metronidazole with Halofantrine can cause an interaction, please consult a doctor before taking it. You should seek immediate medical attention if you develop dizziness, shortness of breath, or heart palpitations. Do not stop using any medications without talking to a doctor.
Ofloxacin + MetronidazoleChlorpropamide
Severe
How does the drug interact with Metrogyl O Tablet:
Co-administration of Ofloxacin and Metronidazole with Chlorpropamide can affect blood glucose levels.

How to manage the interaction:
Although combining Ofloxacin and Metronidazole with Chlorpropamide can lead to interaction, they can be taken on a doctor's advice. If you experience headache, dizziness, rapid heartbeat, increased thirst, and urination, notify a doctor. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleFludrocortisone
Severe
How does the drug interact with Metrogyl O Tablet:
Co-administration of Fludrocortisone and Ofloxacin and Metronidazole can cause tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although taking Fludrocortisone with Ofloxacin and Metronidazole together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have pain, swelling, or inflammation in a muscle area such as the back of the ankle, shoulder, or biceps. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleIvabradine
Severe
How does the drug interact with Metrogyl O Tablet:
Coadministration of Ivabradine with ofloxacin and Metronidazole may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Ofloxacin and Metronidazole with Ivabradine interact, they can be used if prescribed by a doctor. Consult a doctor if you have dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleHydrocortisone
Severe
How does the drug interact with Metrogyl O Tablet:
Co-administration of Hydrocortisone with Ofloxacin and Metronidazole can cause tendinitis (inflammation of the thick fibrous cords that connect muscle to bone) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although taking Hydrocortisone and Ofloxacin together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have pain, swelling, or inflammation in a muscle area such as the back of the ankle, shoulder, or biceps. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleVemurafenib
Severe
How does the drug interact with Metrogyl O Tablet:
Coadministration of Vemurafenib with Ofloxacin and Metronidazole may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Although Ofloxacin and Metronidazole with Vemurafenib interact, they can be used if prescribed by a doctor. Consult a doctor if you have dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.
Ofloxacin + MetronidazoleHaloperidol
Severe
How does the drug interact with Metrogyl O Tablet:
Coadministration of Haloperidol together with ofloxacin and Metronidazole can increase the risk or severity of irregular heart rhythms.

How to manage the interaction:
Although Ofloxacin and Metronidazole with Haloperidol interact, they can be used when prescribed by a doctor. Consult a doctor if you have dizziness, shortness of breath, or heart palpitations. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Metrogyl O Tablet 15's is a combination of two antibiotics that include Ofloxacin and Metronidazole. Ofloxacin prevents the division of bacterial cells and inhibits their repair mechanism, leading to the death of the bacteria. Metronidazole kills parasites and anaerobic bacteria that cause infections. It works by damaging their DNA. Both antibiotics are bactericidal in nature and work together to treat the infection effectively.

Metrogyl O Tablet 15's is a combination of antibacterial (ofloxacin) and anti-amoebic (metronidazole) medication used to treat various infections caused by bacteria. It is also effective in treating diarrhoea due to mixed infections and amoebic dysentery.

It is not advised to take alcohol with Metrogyl O Tablet 15's. Taking alcohol while taking Metrogyl O Tablet 15's can cause serious side effects such as headaches, feeling or being sick, pain in the stomach, hot flushes, a fast or irregular heartbeat, dizziness, drowsiness, etc.

Metrogyl O Tablet 15's can make your skin sensitive to sunlight, a condition known as photosensitivity. So, prolonged exposure to sunlight or ultraviolet light should be avoided. In the event of an emergency, always wear sunscreen before going outdoors.

If you miss a dose of Metrogyl O Tablet 15's, take it as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for the missed one.

No. Metrogyl O Tablet 15's is an antibacterial medicine that acts only against bacterial infections, not against viral infections. You should not take it without consulting your doctor first. Self-medication is dangerous and can lower the efficacy of Metrogyl O Tablet 15's, leading to antibiotic resistance.

Yes, intake of Metrogyl O Tablet 15's may cause dry mouth, and you may feel thirsty frequently. Try to drink plenty of fluids (water with electrolytes) and probiotics. You may also experience dry lips, for which you can use lip balm.

Avoid intake of Metrogyl O Tablet 15's if you have a history of liver diseases, low blood white cells (leukopenia), seizures (fits), gastrointestinal diseases (like Crohn's disease, Inflammatory bowel disease), and other neurological diseases.

The common side effects of Metrogyl O Tablet 15's include nausea, vomiting, stomach upset, loss of appetite, dry mouth, a metallic taste, headache, dizziness, drowsiness, and confusion. Most of these side effects of Metrogyl O Tablet 15's do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

Cnergy It Park, Unit A2, 3rd Floor & Unit A, 8Th Floor, Appa Saheb Marathe Marg, Prabhadevi, Mumbai 400025
Other Info - MET2926
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