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Metrodif-MPS Tablet is used to treat diarrhoea caused by parasitic infections of the intestines, including amoebiasis and giardiasis. It contains Diloxanide furoate, Tinidazole, and Simethicone, which work together to kill the infection-causing parasites in the intestine and prevent the formation and accumulation of excess gas in the gut. It may cause common side effects, such as nausea, vomiting, tiredness, dizziness, headache, loss of appetite, stomach cramps, constipation, and flatulence. Before taking this medication, inform your doctor if you are pregnant or breastfeeding, taking any other medications, or have any pre-existing medical conditions.

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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy
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More about the Product

Manufacturer/Marketer :

Mpi Ethicals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Metrodif-MPS Tablet

Metrodif-MPS Tablet is a prescription tablet used to treat mixed intestinal infections, including amoebiasis and giardiasis, which are caused by tiny parasites. It is specifically designed to clear these infections while simultaneously addressing symptoms like stomach bloating, gas, and abdominal pressure.

To ensure the infection is completely cleared, you must take it regularly and finish the entire course exactly as prescribed by your doctor. It is highly recommended to take this tablet with food to reduce stomach upset and help your body absorb it properly. Drinking plenty of clean, filtered water and avoiding raw or unwashed foods can further support your recovery.

Many people taking it may experience mild side effects such as a temporary metallic taste, nausea, or a dark colouration of their urine. However, if you experience rare but serious signs like numbness in your hands or feet, severe dizziness, or an allergic reaction, stop taking it and contact your doctor immediately.

Before starting it, it is important to inform your doctor if you have a history of liver damage, kidney issues, or nervous system disorders. Do not take this medicine if you have a known allergy to any of its components or have experienced severe neurological side effects from similar treatments.

This medicine interacts strongly with alcohol, which can cause severe nausea, rapid heartbeats, and vomiting, so you must completely avoid drinking alcohol during your treatment and for at least three days after. Also, talk to your doctor or pharmacist if you are pregnant, breastfeeding, or taking blood thinners, as this medicine can affect how those work.

Uses of Metrodif-MPS Tablet

Your doctor may recommend this medicine to help manage the following conditions:

  • Amoebic dysentery and intestinal amoebiasis: It helps by targeting and destroying both the active parasites and their dormant cysts living inside your gut, resolving painful diarrhoea and stomach cramps.
  • Giardiasis: It eliminates the microscopic parasites responsible for this infection, which helps clear up watery diarrhoea, greasy stools, and abdominal pain.
  • Abdominal flatulence and bloating: It works to break down gas bubbles in your stomach and intestines, providing rapid relief from painful pressure, bloating, and fullness associated with gut infections.

Key Benefits

When taken consistently as directed, this medicine may provide the following physiological benefits:

  • Treats the infection: It helps clear intestinal parasites and may help improve bowel movements and stomach discomfort.
  • Relieves bloating and gas: It helps fight the infection while relieving trapped gas, bloating, stomach pressure, and flatulence.

Directions for Use

  • Metrodif-MPS Tablet can be taken with food to prevent stomach upset, or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Swallow Metrodif-MPS Tablet as a whole with a glass of water.
  • Do not break, crush, or chew it.
  • Metrodif-MPS Tablet can be taken with food to prevent stomach upset, or as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Swallow Metrodif-MPS Tablet as a whole with a glass of water.
  • Do not break, crush, or chew it.

How Metrodif-MPS Tablet Works

Metrodif-MPS Tablet contains three active components that work together to clear the infection and comfort your stomach. Diloxanide furoate acts directly inside the intestine to kill the inactive form (cysts) of the amoeba, ensuring the infection cannot return or spread. Simethicone targets the physical gas bubbles trapped in your digestive system. It changes the surface tension of these bubbles, causing them to clump together into larger bubbles that your body can pass much more easily, relieving bloating and pressure almost immediately. Tinidazole enters your body's tissues to destroy the active, growing parasites responsible for your immediate symptoms, such as diarrhoea and severe stomach pain.
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Alcohol

Unsafe

Avoid consuming alcohol while taking Metrodif-MPS Tablet , as it may lead to increased dizziness.

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Pregnancy

Consult your doctor

Please consult your doctor before taking Metrodif-MPS Tablet if you are pregnant or planning to become pregnant. Your doctor will prescribe Metrodif-MPS Tablet only if the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Please consult your doctor before taking Metrodif-MPS Tablet if you are breastfeeding. Your doctor will decide whether Metrodif-MPS Tablet can be taken by breastfeeding mothers or not.

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Driving

Unsafe

Metrodif-MPS Tablet may cause dizziness. Therefore, avoid driving or operating machinery unless you are mentally alert.

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Liver

Caution

Metrodif-MPS Tablet should be used with caution in liver disease. Please inform your doctor before taking Metrodif-MPS Tablet if you have liver impairment.

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Kidney

Caution

Metrodif-MPS Tablet should be used with caution in kidney disease. Please inform your doctor before taking Metrodif-MPS Tablet if you have kidney impairment.

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Children

Caution

Metrodif-MPS Tablet should be used in children only if prescribed by the doctor.

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Heart

Caution

Metrodif-MPS Tablet can generally be used even if you have heart problems, but it should only be done under medical supervision.

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Geriatrics

Caution

Metrodif-MPS Tablet can generally be used in geriatric patients, but it should only be done under medical supervision.

What if I have taken an overdose of Metrodif-MPS Tablet

If you accidentally take more than the prescribed dose of medicine, seek immediate medical attention. Symptoms of an overdose may include severe dizziness, vomiting, or a loss of coordination.

Diet & Lifestyle Advise

  • Practice strict hand hygiene: Wash your hands thoroughly with soap and clean water after using the restroom and before preparing or eating food to prevent reinfection.
  • Drink purified water: Stick to boiled, bottled, or filtered water during your recovery. Avoid ice cubes and tap water, especially when travelling.
  • Avoid raw or unpeeled foods: Eat thoroughly cooked meals and stick to fruits you can peel yourself (like bananas or oranges) to ensure you do not ingest more parasites.
  • Limit gas-producing foods: Avoid carbonated drinks, beans, cabbage, and artificial sweeteners temporarily to help the anti-gas component of your medicine work more effectively.
  • Stay hydrated: Drink plenty of fluids like clear broths or oral rehydration solutions to replace what is lost from diarrhoea and prevent dehydration.
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How Soon It Starts Working

The time required for Metrodif-MPS Tablet to start to work: Metrodif-MPS Tablet shows its action within 1-2 hours of administration. The time for which the effects of Metrodif-MPS Tablet last: The effect of Metrodif-MPS Tablet usually lasts for 24 hours.

What if you forget to take Metrodif-MPS Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store the tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Avoid all alcohol: Do not drink alcohol or use products containing alcohol (like certain cough syrups) during treatment and for at least 72 hours after your final dose to prevent severe abdominal cramps, rapid heartbeats, and vomiting.
  • Finish the entire course: Even if you feel completely better within 48 hours, do not stop taking it early. Skipping doses can allow surviving parasites to become resistant and the infection to return.
  • Watch for nerve symptoms: Contact your doctor immediately if you experience any unusual tingling, numbness, or pins and needles in your fingers or toes.
  • Be cautious when driving: This medication can occasionally cause dizziness or drowsiness. Avoid driving or operating machinery until you know exactly how it affects you.
  • Inspect the blister pack: Always check the packaging before use. If the foil is torn, punctured, or the tablets appear discoloured, do not take them and consult your pharmacist.

verifiedApollotooltip
  • Blood thinners (like warfarin): This medicine may increase the effect of blood thinners, raising your risk of bleeding or bruising.
  • Seizure medicines (like phenytoin or phenobarbital): These drugs can speed up how your body processes this medicine, potentially making it less effective.
  • Lithium: Taking this medicine alongside lithium can increase lithium levels in your blood, raising the risk of toxic side effects.

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verifiedApollotooltip
  • Alcohol: Combining this medicine with alcohol triggers a severe reaction marked by flushing, pounding headaches, rapid heart rate, and vomiting.
     

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Habit Forming

No

Therapeutic Class

[ANTIPROTOZOAL AGENTS, AMEBICIDES]

FAQs

Metrodif-MPS Tablet is used to treat diarrhoea caused by parasitic infections of the intestines, including amoebiasis and giardiasis. It also helps manage symptoms associated with these conditions, such as excess gas in the gut, bloating, stomach pain, and cramps.
Metrodif-MPS Tablet contains three medications: Diloxanide furoate (an amoebicide), Tinidazole (an antiprotozoal), and Simethicone (an anti-foaming agent). Diloxanide furoate works by killing the parasites in the intestine. Tinidazole damages the DNA of parasites, stopping their growth and reproduction. Simethicone breaks down gas bubbles in the gut, reducing their surface tension and making it easier for gas to be released through flatus or belching (burping). It also helps prevent the accumulation and formation of gas in the digestive tract. Together, Metrodif-MPS Tablet helps treat diarrhoea by clearing the infection in the intestines.
Do not stop taking Metrodif-MPS Tablet even if you feel better, as this may cause the infection to return. To treat your condition effectively, continue taking Metrodif-MPS Tablet for as long as your doctor has prescribed it.
Do not take Metrodif-MPS Tablet for longer durations unless prescribed by the doctor, as it may cause unwanted side effects. Talk to your doctor if you do not feel better even after taking Metrodif-MPS Tablet for a week or the prescribed duration.
Metrodif-MPS Tablet might cause a bitter or metallic taste. If you experience any changes in taste, try gargling with water, drinking plenty of fluids, brushing your teeth, or chewing sugar-free mint or gum to reduce the unpleasant taste.
The common side effects of Metrodif-MPS Tablet include nausea, vomiting, tiredness, dizziness, headache, loss of appetite, stomach cramps, constipation, and flatulence. Most of these side effects of Metrodif-MPS Tablet do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
No, you must completely avoid alcohol while taking it and for at least three days after your last dose. Doing so prevents a severe, unpleasant reaction that causes nausea, vomiting, chest pain, and a rapid heartbeat. Talk to your doctor or pharmacist if you have concerns about avoiding alcohol.
It is very common for this medicine to turn your urine a dark, reddish-brown colour. This is a harmless side effect caused by how your body breaks down one of the active ingredients and will go away once your treatment is finished. Talk to your doctor if the colour change persists after completing the course.
You should avoid taking it during pregnancy, particularly in the first trimester, unless your doctor decides it is necessary. If you are pregnant or planning to become pregnant, talk to your doctor before starting this medication.
Some active components of the medicine can pass into breast milk and may affect your baby. It is usually recommended to pause breastfeeding during treatment and for a few days after. Talk to your doctor or pharmacist for specific guidance on how to safely feed your baby.
No, it is best to take it with food or immediately after a meal. Taking it with food helps protect your stomach lining, reduces the chances of nausea, and helps your body absorb the medication properly. Talk to your doctor if you still experience stomach discomfort.
Tingling, numbness, or a pins and needles sensation in your extremities can be a rare but serious side effect of medicine. If you experience this, stop taking the medication and talk to your doctor immediately.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

42 BHAGAT SINGH ROADVILE PARLE (WEST) MUMBAI MH 400056 IN
Other Info - MET1588
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