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  3. Metpure-H Tablet 10's

Metpure-H Tablet 10's, Pack of 10 TABLETS
Metpure-H Tablet 10's, Pack of 10 TABLETS
Metpure-H Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Metpure-H Tablet is used to treat hypertension (high blood pressure) and reduce stroke risk in patients with high blood pressure. It is a combination medication generally used when a single medicine is unable to control high blood pressure. It contains Metoprolol and Hydrochlorothiazide, which work by relaxing the blood vessels. Thus, it helps slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. Also, it removes extra water/fluid and certain electrolyte overload from the body. Thereby, it lowers fluid overload, improves blood flow, lowers blood pressure and reduces the future risk of a heart attack and stroke. It may cause side effects such as nausea, fatigue, constipation, diarrhoea, headache, dizziness, increased blood uric acid, slow heart rate, decreased potassium level in the blood, altered blood lipid level, glucose intolerance, increased calcium level in the blood, and decreased magnesium level in blood.
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Synonym :

S METOPROLOL+HYDROCHLOROTHIAZIDE

Composition :

HYDROCHLOROTHIAZIDE-12.5MG + METOPROLOL-25MG

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Metpure-H Tablet

Metpure-H Tablet is used to treat hypertension (high blood pressure) and reduce stroke risk in patients with high blood pressure. Metpure-H Tablet is a combination medication generally used when a single medicine is unable to control high blood pressure. Hypertension or high blood pressure is a life-long or chronic condition in which the force exerted against the artery wall becomes too high. It can lead to the risk of heart diseases like heart attack and stroke.

Metpure-H Tablet is a combination of two medicines: Metoprolol and Hydrochlorothiazide. Metoprolol belongs to the class of drugs known as β-blockers that work by relaxing the blood vessels by blocking the action of certain natural substances in your body. It helps slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Metpure-H Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke. This medicine needs to be taken regularly to be effective.

Take Metpure-H Tablet as prescribed by your doctor. Depending on your medical conditions, you are advised to take Metpure-H Tablet for as long as your doctor has prescribed it for you. You may experience nausea, fatigue, constipation, diarrhoea, headache, dizziness, increased blood uric acid, slow heart rate, decreased potassium level in the blood, altered blood lipid level, glucose intolerance, increased calcium level in the blood, and decreased magnesium level in blood. Most of these side effects of Metpure-H Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have had an allergic reaction to Metpure-H Tablet , have liver disease, kidney disease, asthma, heart failure, a heart valve problem, or have a history of a heart attack. Pregnant and breastfeeding women should consult their doctor before taking Metpure-H Tablet . Orthostatic hypotension (sudden lowering of blood pressure) might occur, so patients taking Metpure-H Tablet should get up with caution. A prolonged intake of Metpure-H Tablet may decrease your blood potassium levels. So, it is better to ask your doctor about foods high in potassium, like bananas or orange juice. Regular monitoring of blood pressure, kidney function, and electrolytes (sodium, potassium, calcium, etc.) is recommended while taking Metpure-H Tablet . Also, a healthy diet and regular exercise are necessary to keep blood pressure under control.

Uses of Metpure-H Tablet

Treatment of Hypertension (high blood pressure)

Directions for Use

• Take Metpure-H Tablet with or without food or as advised by a doctor.• Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.• Swallow the medicine as a whole with glass of water.• Do not crush, break, or chew it.

Medicinal Benefits

Metpure-H Tablet contains a combination of medicines: Metoprolol (beta-blockers) and Hydrochlorothiazide (thiazide diuretic or water pill). Metoprolol plays a vital role in relaxing our blood vessels by blocking the action of certain natural substances in our bodies. It helps slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Collectively, both help reduce blood pressure and the chance of a stroke, heart attack, and oedema (fluid overload).

How Metpure-H Tablet Works

Metpure-H Tablet is a combination of two medicines: Metoprolol and Hydrochlorothiazide. Metoprolol belongs to the class of drugs known as β-blockers that work by relaxing the blood vessels by blocking the action of certain natural substances in your body. It helps slow down the heart rate, making it easier to pump more blood around your body and lower blood pressure. On the other hand, Hydrochlorothiazide is a diuretic or water pill that works by removing extra water/fluid and certain electrolyte overload from the body. Together, Metpure-H Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Storage

Keep Metpure-H Tablet out of the sight and reach of children.
Side effects of Metpure-H Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Metpure-H Tablet

Do not take more than the prescribed dose of Metpure-H Tablet as it may cause overdose. The symptoms of overdose include slow/fast heart rate, fainiting, trouble breathing or severe dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Don't stop taking Metpure-H Tablet without talking to your doctor first. Stopping Metpure-H Tablet gradually may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will lower your dose gradually over a period of time to help prevent these symptoms. You should not use Metpure-H Tablet if you have allergic to Metpure-H Tablet , have low blood pressure (less than 90 mm of Hg), very slow heartbeat, serious lung condition (like asthma), serious heart condition (sick sinus syndrome), or any heart blockage. Do not use Metpure-H Tablet if you are pregnant, planning for pregnancy, breastfeeding, or unable to urinate (anuria). It should not be given to the children as safety and effectiveness have not been established. Before taking Metpure-H Tablet you should tell the doctor if you have any muscle disorder (myasthenia gravis, rhabdomyolysis), breathing problem (COPD, bronchitis, emphysema), low blood sugar level (hypoglycemia), eye problem (glaucoma), low blood pressure (hypotension), depression, previous heart failure, liver/kidney disease, thyroid hormone disorder like overactive thyroid (hyperthyroidism), adrenal gland cancer, or severe blood circulation problem (Raynaud’s syndrome). You should monitor your blood pressure regularly to make sure the Metpure-H Tablet is working efficiently. Besides this, prolonged intake of Metpure-H Tablet can lead to lowering of blood pressure (hypotension). So, daily monitoring of blood pressure is advisable.

Drug-Drug Interactions

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HydrochlorothiazideDofetilide
Critical
HydrochlorothiazideCisapride
Critical

Drug-Drug Interactions

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HydrochlorothiazideDofetilide
Critical
How does the drug interact with Metpure-H Tablet:
Taking Dofetilide and Metpure-H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Metpure-H Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Metpure-H Tablet:
Taking Cisapride and Metpure-H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Metpure-H Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
MetoprololArtemether
Severe
How does the drug interact with Metpure-H Tablet:
Both Metpure-H Tablet and Artemether may increase the blood levels and effects of Metpure-H Tablet activity.

How to manage the interaction:
Taking Metpure-H Tablet and Artemether together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololElvitegravir
Severe
How does the drug interact with Metpure-H Tablet:
Taking elvitegravir may increase the metabolism of Metpure-H Tablet.

How to manage the interaction:
Although there may be an interaction, Metpure-H Tablet can be taken with Elvitegravir if prescribed by the doctor. Consult the doctor if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medications without talking to your doctor.
MetoprololTizanidine
Severe
How does the drug interact with Metpure-H Tablet:
Coadministration of Metpure-H Tablet and Tizanidine may reduce the efficiency of Metpure-H Tablet.

How to manage the interaction:
Taking Metpure-H Tablet and Tizanidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. do not discontinue any medications without talking to your doctor.
MetoprololAcebutolol
Severe
How does the drug interact with Metpure-H Tablet:
Coadministration of Acebutolol with Metpure-H Tablet can cause abnormal heart rhythm.

How to manage the interaction:
Taking Metpure-H Tablet and Acebutolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololClonidine
Severe
How does the drug interact with Metpure-H Tablet:
Co-administration of Clonidine and Metpure-H Tablet may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Metpure-H Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
MetoprololDisopyramide
Severe
How does the drug interact with Metpure-H Tablet:
Combine use of Metpure-H Tablet with Disopyramide may increase the effectiveness of Disopyramide.

How to manage the interaction:
Although there may be an interaction, Metpure-H Tablet can be taken with Disopyramide if prescribed by the doctor. Consult the doctor if you experience any symptoms such as dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medication without a doctor's advice.
MetoprololSaquinavir
Severe
How does the drug interact with Metpure-H Tablet:
Using Metpure-H Tablet and Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possible interaction between Metpure-H Tablet and Saquinavir, but they can be taken together if your doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, slow pulse, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololVerapamil
Severe
How does the drug interact with Metpure-H Tablet:
Coadministration of Metpure-H Tablet with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Metpure-H Tablet can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume antioxidant-rich food. Blueberries, cherries, tomatoes, squash, and bell peppers are high in antioxidants.

  • Eat natural diuretic foods. Asparagus, beets, green beans, grapes, onion, leafy greens, pineapple, leeks, pumpkin, and garlic are all-natural diuretic foods.

  • Use healthy cooking oils like soybean, olive, canola, and coconut oil.

  • You should avoid refined foods such as white bread, spaghetti, sugar, and red meat.

  • Reduce or eliminate Trans fatty acids, which are found in commercially baked items such as cookies, cakes, crackers, French fries, onion rings, doughnuts, and processed foods.

  • Avoid the consumption of too much salt or salty food.

  • Keep your weight under control with a BMI of 19.5-24.9.

  • Regular physical activity or exercise like walking improves your blood flow.

  • When possible, elevate your legs or the swollen area on a chair or pillows.

  • Avoid standing or sitting for extended periods of time.

  • Avoid chronic stress as it can raise your blood pressure.

  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.

  • Quitting smoking and alcohol consumption is the best strategy to lower the risk of many health complications.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Metpure-H Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Drinking alcohol may increase tiredness, lower blood pressure causing dizziness or drowsiness. So avoid its intake with Metpure-H Tablet

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Pregnancy

Caution

Metpure-H Tablet is a pregnancy category C drug. It is not recommended during pregnancy unless your doctor considers it essential. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

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Breast Feeding

Caution

Small amounts of Metpure-H Tablet passes into the breast milk. However which is not enough to cause any problems to your baby. But, still, it is advisable to contact your doctor before breastfeeding your baby.

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Driving

Caution

You may experience dizziness, tiredness, or blurred vision while taking Metpure-H Tablet . So, it is not recommended to drive, use machinery, or perform other tasks.

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Liver

Caution

Metpure-H Tablet should be used with caution in patients with impaired hepatic function or progressive liver disease since minor alterations of fluid and electrolyte balance may precipitate hepatic coma. Your doctor may adjust your dose depending upon your current liver conditions.

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Kidney

Caution

Metpure-H Tablet to be taken with caution, especially if you have had a history of kidney disease. Your doctor will have to change the dosage depending on your medical condition and your reaction to treatment.

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Children

Unsafe

The safety and efficacy of Metpure-H Tablet in children have not been established. Metpure-H Tablet is not recommended in children.

Have a query?

FAQs

Metpure-H Tablet is used to treat hypertension (high blood pressure) and reduce stroke risk in patients with high blood pressure. It is a combination medication generally used when a single medicine is unable to control high blood pressure.

Metpure-H Tablet contains a combination of drugs, namely; Metoprolol and Hydrochlorothiazide. Metoprolol is a beta-blocker that works specifically on the heart to reduce heart rate and make the heart more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic that lowers blood pressure by removing extra water and certain electrolytes from the body. Over time it also relaxes blood vessels and improves blood flow.

Use of Metpure-H Tablet in diabetes may mask tachycardia (fast heart rate) occurring with low blood sugar level, but other symptoms like dizziness and sweating may not be significantly affected. So, if you are diabetic patients always consult a doctor before taking Metpure-H Tablet .

Your doctor may probably tell you to stop taking Metpure-H Tablet as it lowers blood pressure (hypotension) when combined with general anesthesia before surgery. So, please inform your doctor before surgery if you are taking Metpure-H Tablet .

No, Metpure-H Tablet is not recommended if you have frequent asthma attacks, severe asthma, or COPD (chronic obstructive pulmonary disease). Metoprolol in Metpure-H Tablet may cause wheezing (bronchospasm) and dyspnea. Thereby, it can make asthma worse. It is advised to consult your doctor before taking Metpure-H Tablet . You may need a dose adjustment and more frequent monitoring of your lung function to safely use both medications.

Metpure-H Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor. Discontinuing Metpure-H Tablet may lead to increased blood pressure with a high risk of heart attack and stroke in the future.

Yes, prolonged intake of Metpure-H Tablet may decrease your potassium levels in the bloodstream. So, it is better to ask your doctor about foods high in potassium like bananas or orange juice. Besides this, consult a doctor regarding the use of table salt or sodium chloride, or salt substitute containing potassium.

Hydrochlorothiazide in Metpure-H Tablet may make your more skin more sensitive to the sun and may also increase your risk for skin cancer if used for a long time. Try to limit your time in the sun and avoid tanning booths and sunlamps. You can also use sunscreen and wear protective clothing when outdoors.

Metpure-H Tablet can be taken with meals or immediately after meals. Swallow Metpure-H Tablet as a whole with water; do not crush or chew it.

The side effects of Metpure-H Tablet include nausea, fatigue, headache, dizziness, diarrhoea, stuffynose, sore throat, slow heart rate and glucose intolerance. Consult the doctor if any of these side effects persist or worsen.

Do not drink alcohol while taking Metpure-H Tablet as it might increase blood pressure-lowering effect of Metpure-H Tablet and cause drowsiness.

Metpure-H Tablet should be stored at room temperature and away from excess heat and moisture. Keep it out of sight and reach of children.

The serious side effects of Metpure-H Tablet include bronchospasm (constriction of air passages of the lung), slow heart rate, weak pulse, fainting, slow breathing , blurred vision, tunnel vision, eye pain, or seeing halos around lights, low potassium level, leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling(lacking in strength), or low sodium level headache, confusion, slurred speech, severe weakness, vomiting, loss of coordination, feeling unsteady. Consult doctor if you experience any of these side effects.

Country of origin

India

Manufacturer/Marketer address

255/2, Hinjawadi, Pune - 411057, India
Other Info - MET0041

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:44 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/cdi/metoprolol-and-hydrochlorothiazide-tablets.html
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021956s003lbl.pdf

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