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compositionComposition:CLONAZEPAM-0.5MG+MELATONIN-3MG
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Prescription Medicine
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Metotrip LS Tablet 10's is used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. Additionally, it can help treat sleep disorders like jet lag and insomnia, which are caused on by disruptions in the body's natural circadian cycle. Metotrip LS Tablet 10's contains clonazepam and melatonin. Clonazepam works by inhibiting abnormal electrical activity in the brain cells. It calms you down and lessens anxiety and seizure episodes. Melatonin helps synchronize its sleep-wakefulness cycle, or day-and-night rhythm. This helps you travel across time zones by reducing the symptoms of sleep problems and adjusting your sleep cycles. Together, these medications help you fall asleep and relax your brain. In some cases, Metotrip LS Tablet 10's may cause side effects such as drowsiness, dizziness, fatigue, and problems with memory, walking, and coordination. Prior to using this medication, inform your doctor about any allergies to its ingredients, pregnancy or breastfeeding status, current medications, and pre-existing medical conditions to ensure safe and effective treatment.

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Written By ,
Reviewed By Praneetha Akunuri , M.Pharmacy
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More about the Product

Composition :

CLONAZEPAM-0.5MG+MELATONIN-3MG

Manufacturer/Marketer :

Tripada Healthcare Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Metotrip LS Tablet 10's

This medicine is a prescription combination used for short-term sleep difficulties associated with anxiety when your doctor believes it is appropriate. Clonazepam is not a first-line or standard approved sleep medicine, and this combination is prescribed for sleep only in selected patients under medical supervision.One of its components, clonazepam, is a long-acting benzodiazepine whose primary approved uses include seizure disorders and panic disorder, and it should be used only under medical supervision Because clonazepam stays in the body for a long time, its calming and sedative effects may persist into the next day in some people. This is why it is important to use the dose and duration exactly as prescribed by your doctor.

It is important to take Metotrip LS Tablet 10's consistently at the exact time prescribed by your doctor before bedtime. You can take this tablet with or without food, but taking it at a consistent time each night yields the best results. Combining this treatment with a quiet sleep environment and a regular bedtime routine can significantly enhance its effectiveness.

While taking this medicine, you might experience mild side effects like daytime drowsiness, lightheadedness, or dry mouth. If you experience severe issues such as extreme confusion, breathing difficulties, or unusual mood changes, you must contact your doctor immediately.

Before starting Metotrip LS Tablet 10's, talk to your doctor if you have a history of liver damage, kidney problems, or breathing disorders. Do not take this medicine if you have severe lung disease, sleep apnea, or severe muscle weakness.

Avoid alcohol and other sedatives while taking this medicine, as they can cause dangerous levels of sleepiness and slow down your breathing. If you are pregnant, breastfeeding, or an older adult, consult your doctor before using this medication to ensure it is safe for your specific situation.

Uses of Metotrip LS Tablet 10's

Your doctor may prescribe Metotrip LS Tablet 10's to help manage the following sleep-related conditions:

  • Insomnia associated with anxiety: Metotrip LS Tablet 10's helps by calming hyperactive nerve cells and relaxing your mind, making it easier to fall asleep when anxiety keeps you awake.
  • Sleep timing difficulties: Your doctor may occasionally consider this medicine when anxiety is contributing to disturbed sleep timing, but it is not a standard treatment for sleep cycle disorders.
     

Key Benefits

Using Metotrip LS Tablet 10's as prescribed helps improve sleep quality and reduce anxiety-related sleep disturbances. Here are the key benefits you can expect:

  • Helps you fall asleep faster: Metotrip LS Tablet 10's calms the mind, reducing the time it takes to fall asleep when anxiety or restlessness makes it difficult to sleep.
  • Promotes uninterrupted sleep: Metotrip LS Tablet 10's helps reduce frequent awakenings during the night, allowing for longer, more restful sleep.
  • Improves next-day well-being: By promoting a calmer state of mind and better-quality sleep, Metotrip LS Tablet 10's helps you wake up feeling more refreshed and less tired during the day.
Side effects of Metotrip LS Tablet
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
  • Approach calmly, use a non-threatening tone, actively listen, validate concerns, and provide clear instructions.
  • Practice environmental changes like adjusting lighting, noise levels, and providing a safe space.
  • Recognizing and praising desired behaviors.
  • Maintaining consistent schedules for daily activities.
  • Try to engage in calming activities to redirect focus.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Uncoordinated muscle movements need immediate medical attention.
  • Observe your movements and try to understand and control the particular movement.
  • Regularly do strengthening exercises to improve blood flow throughout the body and avoid involuntary movements.
  • Implement massage techniques to enhance blood flow to organs.
  • Take a balanced diet and quit smoking.
  • Practice yoga and meditation to improve thought processes and reduce uncontrolled and involuntary movements.
Managing Medication-Triggered Bronchitis (Inflammation of the bronchial tubes): A Step-by-Step Guide:
  • If you experience symptoms like coughing, wheezing, chest tightness, or difficulty breathing after taking medication, seek medical attention immediately.
  • Your healthcare provider will work with you to stop the medication causing the reaction, start alternative treatments, and provide supportive therapy.
  • To manage symptoms and prevent complications, follow your doctor's advice to use inhalers or nebulizers as prescribed, practice good hygiene, avoid irritants, stay hydrated, and get plenty of rest.
  • Regularly track your symptoms and report any changes or concerns to your healthcare provider.

Directions for Use

  • Metotrip LS Tablet 10's can be taken with or without food. However, taking it with food may help reduce any potential stomach discomfort.
  • Follow your doctor’s instructions on the dosage and timing of this medication. It is recommended to take this medicine at evenly spaced intervals for consistent relief and effectiveness.
  • Swallow the whole tablet with a glass of water.
  • Do not break, chew or crush Metotrip LS Tablet 10's.

How Metotrip LS Tablet 10's Works

Metotrip LS Tablet 10's contains clonazepam and melatonin, which work together to promote restful sleep and reduce anxiety. Clonazepam belongs to the benzodiazepine class of medicines. It enhances the activity of gamma-aminobutyric acid (GABA), a natural calming chemical in the brain. This helps reduce excessive nerve activity, relieving anxiety, relaxing muscles, and promoting a sense of calm that makes it easier to fall asleep. Melatonin is a hormone that helps regulate the body's natural sleep–wake cycle. It signals to the brain that it is time to sleep, helping restore a normal sleep pattern and improving sleep quality. Together, clonazepam and melatonin help reduce anxiety, promote the onset of sleep, improve sleep continuity, and support a more regular sleep cycle.
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Alcohol

Unsafe

Avoid consumption of alcohol while taking Metotrip LS Tablet 10's as it may cause increased drowsiness.

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Pregnancy

Unsafe

Metotrip LS Tablet 10's belongs to pregnancy Category D. It is usually not recommended during pregnancy. However, if you are pregnant or intend to become pregnant, consult your doctor.

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Breast Feeding

Unsafe

Avoid taking Metotrip LS Tablet 10's if you are breastfeeding as it passes into breastmilk. Please consult your doctor for more information.

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Driving

Unsafe

Metotrip LS Tablet 10's causes dizziness and sleepiness. After taking this medication, avoid operating machinery or driving.

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Liver

Consult your doctor

Metotrip LS Tablet 10's to be taken with caution, especially if you have a history of liver problems. Your doctor may need to change the dosage.

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Kidney

Consult your doctor

Please consult your doctor if you have kidney impairment or any concerns before taking Metotrip LS Tablet 10's.

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Children

Consult your doctor

Please consult your doctor. Depending on the child's age, weight, and condition, your doctor may determine the dosage and length of time.

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Heart

Caution

Metotrip LS Tablet 10's should be used with caution if you have a history of heart diseases or conditions. Your doctor will decide whether to administer it if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available about the use of Metotrip LS Tablet 10's in geriatric patients. Please consult your physician.

What if I have taken an overdose of Metotrip LS Tablet 10's

If you suspect an overdose, seek emergency medical care immediately. Symptoms of an overdose may include extreme sleepiness, confusion, severe muscle weakness, or difficulty breathing.

Diet & Lifestyle Advise

  • Maintain a regular sleep schedule: Go to bed and wake up at the same time every day, including weekends, to help support a healthy sleep–wake cycle.
  • Avoid stimulants before bedtime: Avoid caffeine, nicotine, and heavy meals for at least 4 to 6 hours before going to bed, as they can interfere with sleep.
  • Create a sleep-friendly environment: Keep your bedroom dark, quiet, and comfortably cool to promote restful sleep.
  • Limit screen time: Avoid using smartphones, tablets, televisions, and other bright screens for at least 1 hour before bedtime, as blue light can interfere with natural melatonin production.
  • Practice relaxing bedtime habits: Engage in calming activities such as reading a book, listening to soothing music, or practising deep-breathing exercises before going to sleep.
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How Soon It Starts Working

The time required for Metotrip LS Tablet 10's to start to work: The peak effect of Metotrip LS Tablet 10's can be observed within 20-60 minutes of administration. The time for which the effects of Metotrip LS Tablet 10's last: The duration of Metotrip LS Tablet 10's effect is clinically unknown.

What if you forget to take Metotrip LS Tablet 10's

If you miss a dose, take it as soon as you remember if it is still before your bedtime. If you wake up in the middle of the night or if it is close to morning, skip the missed dose and resume your regular schedule the following night. Do not take a double dose to make up for a forgotten one.

Storage

• Store in a cool and dry place away from sunlight.• Keep Metotrip LS Tablet 10's out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Avoid activities requiring alertness: Do not drive, operate heavy machinery, or perform hazardous tasks after taking Metotrip LS Tablet 10's, as it may cause significant drowsiness and impair alertness.
  • Avoid alcohol: Do not consume alcohol while taking Metotrip LS Tablet 10's, as it can increase drowsiness and may slow breathing.
  • Do not stop the medicine suddenly: Never stop taking Metotrip LS Tablet 10's without your doctor's advice. Abrupt discontinuation may cause withdrawal symptoms such as anxiety, sweating, tremors, sleep disturbances, or seizures. Your doctor will advise you on how to reduce the dose gradually.
  • Check before use: Inspect the blister pack before taking a tablet. Do not use it if the packaging is damaged or if the tablet appears discoloured or broken.
  • Inform healthcare providers: Tell your doctor, dentist, surgeon, or other healthcare professionals that you are taking Metotrip LS Tablet 10's before any medical, dental, or surgical procedure.
  • Use for the shortest duration possible: This medicine is usually prescribed for short-term use. Do not continue it beyond the period advised by your doctor, and never increase the dose on your own. 

Drug-Drug Interactions

verifiedApollotooltip
  • Other sleep aids or sedatives: Combining these can cause extreme drowsiness and dangerous respiratory depression.
  • Opioid pain relievers: Taking these together increases the risk of severe sleepiness, breathing difficulties, and coma.
  • Certain antidepressants or anxiety medications: May enhance the calming effects, leading to excessive drowsiness and coordination issues.
  • Certain antifungal medicines (such as azole antifungals) and some antibiotics: These medicines may increase clonazepam levels in the body and raise the risk of excessive drowsiness and other side effects. Tell your doctor about all prescription medicines you are taking. 
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Significantly increases the sedative effects of this medicine, which can lead to dangerously slow breathing and extreme dizziness.
  • Caffeine: May reduce the effectiveness of this medicine by stimulating brain activity and preventing sleepiness.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[ANTICONVULSANT, SEDATIVE-HYPNOTIC DRUGS]

FAQs

Metotrip LS Tablet 10's is used to treat seizures or fits due to epilepsy, panic disorder and involuntary muscle spasms. Additionally, it can help treat sleep disorders like jet lag and insomnia, which are caused by disruptions in the body's natural circadian cycle.
Metotrip LS Tablet 10's contains clonazepam and melatonin. Clonazepam works by inhibiting abnormal electrical activity in the brain cells. It calms you down and lessens anxiety and seizure episodes. Melatonin aids in the synchronization of its day-and-night rhythm or sleep-wakefulness cycle. This helps you travel across time zones by reducing the symptoms of sleep problems and adjusting your sleep cycles. Together, these medications help you fall asleep and relax your brain.
Metotrip LS Tablet 10's is a controlled and habit-forming drug. If you take it for two to four weeks, it is unlikely to become addictive. However, if Metotrip LS Tablet 10's is prescribed for more than 2-4 weeks, your doctor may reduce your dose gradually before completely stopping it to avoid withdrawal symptoms.
Do not stop taking Metotrip LS Tablet 10's until instructed by your doctor. Stopping Metotrip LS Tablet 10's may cause withdrawal symptoms like seizures that do not stop, hallucinations (hearing or seeing things that are not there), shaking, and stomach and muscle cramps. To avoid this, your doctor might gradually reduce the dosage.
Consuming caffeine may decrease the calming effects of Metotrip LS Tablet 10's. So, it is advisable to avoid consuming caffeinated beverages like coffee, tea, cola, or chocolate containing caffeine. Avoid smoking and alcohol consumption as it can increase nervous system side effects such as dizziness, drowsiness, and difficulty concentrating.
The duration of Metotrip LS Tablet 10's depends on the condition being treated. Your doctor will decide how long you need to take Metotrip LS Tablet 10's and may adjust the duration based on your age or specific condition. Please consult your doctor for the right duration of Metotrip LS Tablet 10's.
Metotrip LS Tablet 10's is generally safe when taken as prescribed by your doctor. However, if taken excessively or over an extended period of time, it may result in adverse consequences such as dependency, sleepiness, and dizziness. To reduce hazards, always follow your doctor's advice.
Yes, Metotrip LS Tablet 10's can make you sleepy, drowsy, or tired. Therefore, if you feel sleepy or fatigued, avoid operating heavy machinery or tools or driving. Avoid drinking alcohol, as it can make you feel even more tired.
Metotrip LS Tablet 10's is not commonly associated with weight gain. Please consult your doctor if you’re concerned about weight changes or side effects.
Yes, you can take Metotrip LS Tablet 10's with paracetamol if advised by the doctor, as they do not have significant drug-drug interactions. However, please consult with your doctor before taking Metotrip LS Tablet 10's with paracetamol.
The common side effects of Metotrip LS Tablet 10's include drowsiness, dizziness, fatigue, and problems with memory, walking, and coordination. Please let your doctor know if these side effects worsen.
You should only take Metotrip LS Tablet 10's exactly as prescribed by your doctor. It is typically recommended for short-term use, as long-term use can lead to dependence. Talk to your doctor if your sleep does not improve.
No, you must avoid alcohol entirely while taking this medication. Alcohol can severely increase drowsiness and cause dangerously slow breathing. Talk to your doctor if you have concerns about avoiding alcohol.
This medication is generally not recommended during pregnancy or breastfeeding as it may affect the baby. Always talk to your doctor to weigh the risks and benefits before using this medicine.
Yes, one of the active components in this medicine has the potential to cause dependence, especially if used for a prolonged period or at higher doses. Always follow your doctor's prescribed schedule strictly. Talk to your doctor if you have a history of substance use.
Take this medicine exactly at the time recommended by your doctor before bedtime. The appropriate timing can vary depending on the specific formulation and your sleep pattern. Do not change the timing on your own, and make sure you have enough time for a full night's sleep after taking the medicine.
This medicine can interact with several other drugs, especially those that affect the nervous system. Provide your doctor or pharmacist with a complete list of all medications, supplements, and herbal products you are currently taking. Talk to your doctor before starting any new treatment.
Yes. Many people benefit from non-medicine approaches such as maintaining a regular sleep schedule, keeping the bedroom dark and quiet, avoiding screens before bedtime, and practising relaxation techniques. Your doctor may also recommend cognitive behavioural therapy for insomnia (CBT-I), which can help improve sleep and may reduce the need for sleeping medicines over time. Talk to your doctor about the best approach for you.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. Electronic Medicines Compendium (EMC). Pil.10405 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Clonazepam With Melatonin 703 0 1548 0 Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. U.S. Food and Drug Administration (FDA). 017533S053,020813S009Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  4. National Health Service (NHS). Insomnia - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  5. National Health Service (NHS). Jet Lag - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  6. Drugs.com Clinical Review Team. Alfentanil With Clonazepam 118 0 703 0 Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  7. Hajira Basit; Chadi I. Kahwaji. Clonazepam. StatPearls. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. September 2022. [Accessed on 27th February 2023]Check here

Country of origin

India

Manufacturer/Marketer address

3 Yogi Complex, Nr Doordarshan, Kendra, Thaltej, Ahmedabad, India 380054.
Other Info - MET2816

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