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compositionComposition:THIAMAZOLE-10MG
prescription
Prescription Medicine
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Methirox-10 Tablet 30's is used to treat hyperthyroidism (overactive thyroid gland). Besides this, it also treats Graves' disease (an autoimmune disease that causes overactive thyroid), thyroid storm (excessive release of thyroid hormones) and toxic multinodular goitre. It contains Thiamazole which decreases the production of thyroid hormones by the thyroid gland. Thus, it is used before thyroid surgery or radioactive iodine treatment. It may cause side effects such as vomiting, headache, nausea, skin rash, muscle or joint pain, changes in the colour of the skin, hair loss or paraesthesia (tingling or pricking sensation). Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

THIAMAZOLE-10MG

Manufacturer/Marketer :

Orris Pharmaceuticals

Consume Type :

Oral

Expires on or after :

Jan-29

Return Policy :

Not Returnable

About Methirox-10 Tablet 30's

Methirox-10 Tablet 30's is an oral prescription medicine used to treat an overactive thyroid, a condition known as hyperthyroidism. This medication helps control the excessive production of thyroid hormones, restoring a healthy metabolic balance in your body. Doctors also prescribe Methirox-10 Tablet 30's to prepare patients for thyroid surgery or radioactive iodine treatment.

For the best results, you must take Methirox-10 Tablet 30's consistently every day. You can take Methirox-10 Tablet 30's with or without food, but you should choose one method and stick to it with every dose to ensure steady absorption. Making adjustments to your lifestyle, such as limiting foods extremely high in iodine, can also help support your treatment goals.

While taking Methirox-10 Tablet 30's, you may experience mild side effects like nausea, skin rashes, or temporary joint discomfort. However, you must contact your doctor immediately if you develop serious symptoms such as a sudden sore throat, fever, or signs of liver damage like yellowing of your skin or eyes.

Do not take this if you have had a severe allergic reaction to this medication or other thyroid-suppressing medicines in the past. Before starting this treatment, talk to your doctor if you have a history of blood disorders, liver problems, or a weakened immune system.

Methirox-10 Tablet 30's can interact with certain blood thinners, heart medications, and blood pressure drugs, which may require your healthcare provider to adjust your dose. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider, as special monitoring or alternative treatments are usually required to protect your baby.

Uses of Methirox-10 Tablet 30's

Methirox-10 Tablet 30's is used in the treatment of hyperthyroidism (overactive thyroid). The detailed uses of Methirox-10 Tablet 30's are as follows:

  • Hyperthyroidism: Methirox-10 Tablet 30's helps by reducing the overproduction of thyroid hormones, which relieves symptoms like rapid heart rate, weight loss, and anxiety.
  • Graves' Disease: Methirox-10 Tablet 30's manages the thyroid overactivity caused by this autoimmune condition, helping to stabilize hormone levels.
  • Preparation for Thyroid Surgery: Taking this medication before surgery helps lower thyroid hormone levels to safer ranges, reducing the risk of complications during the procedure.
  • Preparation for Radioactive Iodine Therapy: It stabilizes thyroid function before you undergo radioactive iodine treatment.

Key Benefits

Methirox-10 Tablet 30's helps manage an overactive thyroid by helping restore thyroid hormone levels to a healthier range. As thyroid function improves, many symptoms of hyperthyroidism become easier to manage, supporting better overall well-being and daily functioning. Benefits may include:

  • Helps reduce symptoms such as hand tremors, excessive sweating, and heat intolerance.
  • Supports the maintenance of a normal heart rate and cardiovascular function.
  • Helps relieve feelings of anxiety, restlessness, and nervousness associated with hyperthyroidism.
  • Reduces fatigue and supports improved energy levels as thyroid hormone levels stabilize.
  • Helps prevent unintended weight loss caused by an overactive metabolism.
  • Supports long-term control of hyperthyroidism and improves overall quality of life.

Directions for Use

  • Take Methirox-10 Tablet 30's with food or as prescribed by a doctor.
  • It is advised to take Methirox-10 Tablet 30's once daily, or as directed by your doctor, at the same time each day for best results.
  • Swallow Methirox-10 Tablet 30's as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Methirox-10 Tablet 30's Works

Methirox-10 Tablet 30's works by targeting the thyroid gland directly to stop it from making too much thyroid hormone. It specifically blocks an enzyme in your thyroid that is responsible for combining iodine with proteins to create thyroid hormones. By preventing this chemical process, the medicine gradually lowers the level of circulating thyroid hormones in your bloodstream. This action does not destroy existing thyroid tissue or affect hormones that have already been made and stored; instead, it prevents new hormones from being formed, slowly restoring your body's natural metabolic balance over several weeks.
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Alcohol

Caution

The interaction of Methirox-10 Tablet 30's with alcohol is unknown. Please consult a doctor before consuming alcohol while using Methirox-10 Tablet 30's.

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Pregnancy

Unsafe

Methirox-10 Tablet 30's is a Category D pregnancy drug and is not recommended for pregnant women as it may cause harm to the unborn baby.

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Breast Feeding

Caution

Methirox-10 Tablet 30's is excreted in human milk. Therefore, please consult a doctor if you are breastfeeding. Methirox-10 Tablet 30's is given to breastfeeding mothers only if the doctor thinks benefits are greater than risks.

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Driving

Caution

Methirox-10 Tablet 30's may decrease alertness in some people. So, drive only if you are alert after taking Methirox-10 Tablet 30's.

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Liver

Caution

Methirox-10 Tablet 30's should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Methirox-10 Tablet 30's should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Methirox-10 Tablet 30's should be used with caution in children if prescribed by a doctor.

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Heart

Consult your doctor

It is important to consult your physician before taking Methirox-10 Tablet 30's in cardiac patients.

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Geriatrics

Safe if prescribed

Methirox-10 Tablet 30's is safe for use in elderly patients if prescribed by the physician.

What if I have taken an overdose of Methirox-10 Tablet 30's

In case of an accidental overdose, seek immediate emergency medical attention or contact a poison control center right away. Symptoms of an overdose may include fever, joint pain, skin rash, or extreme fatigue.

Diet & Lifestyle Advise

  • Avoid iodine-rich foods: Limit your intake of foods very high in iodine, such as seaweed, kelp, iodized salt, and certain seafoods, as excess iodine can interfere with the medicine's ability to lower thyroid hormones.
  • Get regular blood tests: Attend all scheduled laboratory appointments to monitor your thyroid hormone levels and liver function, which helps your doctor ensure the treatment is working safely.
  • Manage stress levels: High stress can worsen hyperthyroid symptoms like rapid heart rate and anxiety; practicing relaxation techniques like deep breathing or meditation can support your recovery.
  • Avoid intensive exercise initially: Consult your doctor before starting any intense physical activity, especially if you have a rapid or irregular heartbeat caused by hyperthyroidism.
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How Soon It Starts Working

The time required for Methirox-10 Tablet 30's to start to work: The time required for Methirox-10 Tablet 30's to start to work is 1 to 2 hours after administration. 

The time for which the effects of Methirox-10 Tablet 30's last: The effect of Methirox-10 Tablet 30's lasts for 24 hours.

What if you forget to take Methirox-10 Tablet 30's

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Watch for signs of infection: Contact your doctor immediately if you develop a sore throat or fever, as this can be an early sign of a rare but serious blood condition.
  • Monitor your liver health: Alert your healthcare provider immediately if you notice yellowing of your skin or the whites of your eyes, or if your urine becomes unusually dark.
  • Prioritize consistency: Take your dose at the same time every day to keep a stable amount of the medicine in your body.
  • Inform all healthcare providers: Let all your doctors, dentists, and surgeons know that you are taking Methirox-10 Tablet 30's before undergoing any medical procedures or starting new medications.
  • Do not stop suddenly: Never stop taking this medication abruptly without consulting your doctor, as your hyperthyroid symptoms could return quickly.

Drug-Drug Interactions

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Drug-Drug Interactions

  • Blood thinners (e.g., warfarin): Taking these medicines alongside Methirox-10 Tablet 30's may affect how blood thinners work, increasing the risk of bleeding or reducing their effectiveness. Closer monitoring may be required.
  • Beta-blockers (e.g., propranolol, atenolol): As thyroid hormone levels return to normal during treatment with Methirox-10 Tablet 30's, your response to beta-blockers may change, and dose adjustments may be needed.
  • Heart medication (e.g., digoxin): Treatment with Methirox-10 Tablet 30's may increase digoxin levels in the body as hyperthyroidism improves, potentially increasing the risk of side effects and requiring a dose adjustment.
  • Breathing disorders medication (e.g., theophylline): As thyroid function normalizes during treatment with Methirox-10 Tablet 30's, the body may clear theophylline more slowly, which could increase the risk of side effects and require dose adjustments.

Drug-Food Interactions

  • Iodine-rich foods and supplements: Consuming large amounts of iodine through seaweed, kelp, or dietary supplements can reduce the effectiveness of Methirox-10 Tablet 30's.

Drug-Disease Interactions

  • Liver disease: If you have pre-existing liver impairment, your body may struggle to process this medication, increasing the risk of side effects.
  • Blood disorders (bone marrow depression): People with a history of low white blood cell counts should use Methirox-10 Tablet 30's with extreme caution, as it can further lower blood cell production.
MethimazoleMipomersen
Severe
MethimazoleFluphenazine
Severe

Drug-Drug Interactions

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MethimazoleMipomersen
Severe
How does the drug interact with Methirox-10 Tab:
The combined use of Mipomersen and Methirox-10 Tab together can increase the liver problems.

How to manage the interaction:
Although there is a possible interaction between Methirox-10 Tab and Mipomersen, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, contact a doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, bleeding, pain, dark urine, or liver damage. Do not stop using any medications without talking to a doctor.
MethimazoleFluphenazine
Severe
How does the drug interact with Methirox-10 Tab:
Co-administration of Fluphenazine and Methirox-10 Tab together can cause the risk of neutropenia leading to serious infections.

How to manage the interaction:
Although there is a possible interaction between Methirox-10 Tab and Fluphenazine, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - fever, chills, body aches, sore throat, coughing, breathing difficulties, mouth ulcers, or flu-like symptoms - contact a doctor right away. Do not stop using any medications without talking to a doctor.
MethimazoleLomitapide
Severe
How does the drug interact with Methirox-10 Tab:
Taking Lomitapide and Methirox-10 Tab together can increase the risk of liver problems.

How to manage the interaction:
Although taking Methirox-10 Tab and Lomitapide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, contact a doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, bleeding, dark urine, or liver damage. Do not stop using any medications without a doctor's advice.
MethimazoleTeriflunomide
Severe
How does the drug interact with Methirox-10 Tab:
The combined use of Methirox-10 Tab with Teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Taking Methirox-10 Tab with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, liver damage, or bleeding. Do not discontinue any medications without consulting a doctor.
MethimazoleClozapine
Severe
How does the drug interact with Methirox-10 Tab:
When Clozapine is taken with Methirox-10 Tab, the effects of Clozapine increases.

How to manage the interaction:
There may be a possibility of interaction between Methirox-10 Tab and Clozapine, but it can be taken if prescribed by a doctor. If you have any of these symptoms - feeling weak, having a sore throat, fever, mouth sores, feeling tired or having flu-like symptoms, contact a doctor right away. Do not stop using any medications without a doctor's advice.
MethimazolePropylthiouracil
Severe
How does the drug interact with Methirox-10 Tab:
Taking Propylthiouracil with Methirox-10 Tab can increase the risk of side effects.

How to manage the interaction:
Co-administration of Propylthiouracil with Methirox-10 Tab can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MethimazoleDeferiprone
Severe
How does the drug interact with Methirox-10 Tab:
Taking Methirox-10 Tab with Deferiprone may increase the risk of severe infections.

How to manage the interaction:
Taking Methirox-10 Tab with Deferiprone together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms - like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination - contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[THYROID AND ANTITHYROID AGENTS]

FAQs

Methirox-10 Tablet 30's is used to treat hyperthyroidism (overactive thyroid gland). Besides this, it also treats Grave's disease (an autoimmune disease that causes overactive thyroid), thyroid storm (excessive release of thyroid hormones) and toxic multinodular goitre.
Methirox-10 Tablet 30's contains Thiamazole, an anti-thyroid agent that works by decreasing the production of thyroid hormones by the thyroid gland. Thus, balances the levels of thyroid hormones.
Yes, Methirox-10 Tablet 30's may be used before thyroid surgery to provide relief from symptoms of hyperthyroidism (overactive thyroid gland) such as anxiety, irregular or rapid heartbeat or sweating.
Methirox-10 Tablet 30's may cause low blood sugar levels in some patients. However, if you experience dizziness, hunger, confusion, shaking, fast heartbeat, drowsiness, weakness or headache, please consult a doctor as these might be signs of low blood sugar.
You are not recommended to take Methirox-10 Tablet 30's with warfarin (blood thinner) as it may increase the risk of bleeding more easily. However, please consult a doctor before taking Methirox-10 Tablet 30's with other medicines.
Methirox-10 Tablet 30's should be used with extreme caution in patients suffering from agranulocytosis (severe low white blood cells count) as it may worsen the condition. However, if you experience shortness of breath, fever, pale skin, sore throat or tiredness, please consult a doctor immediately.
If you have any liver problems, it is advised to inform your doctor before taking Methirox-10 Tablet 30's. Methirox-10 Tablet 30's may increase the risk of liver damage if there is any existing liver problem. Therefore, liver functions tests are recommended while taking Methirox-10 Tablet 30's to monitor liver functioning.
It usually takes several weeks (about 4 to 8 weeks) for your thyroid hormone levels to normalize and for you to feel significant symptom relief. This is because the medication prevents new hormone production but does not affect the hormones already stored in your body. Talk to your doctor if you do not notice any improvement after a month.
If you are pregnant or planning to become pregnant, you must discuss this with your doctor immediately. Methirox-10 Tablet 30's can cross the placenta and potentially cause harm to an unborn baby, especially during the first trimester, so your doctor may recommend alternative treatments or closely monitor your dose. Talk to your doctor.
Yes, you should limit your intake of foods and supplements that are very rich in iodine, such as seaweed, kelp, and iodized salt, because excess iodine can make the medication less effective. Talk to your doctor or a dietitian for personalized dietary advice.
There is no direct interaction between alcohol and Methirox-10 Tablet 30's, but moderate to heavy alcohol consumption can strain your liver and mask symptoms of liver damage, which is a rare side effect of the medication. It is best to limit alcohol intake and talk to your doctor.
Not necessarily. While some patients take it for a long period, many use it for 12 to 18 months to see if their hyperthyroidism goes into remission. Your doctor will monitor your blood work periodically to decide if you can safely stop taking it. Talk to your doctor.
It is best to take your dose at the same time every day to maintain a consistent level of the medication in your body. Whether you take it in the morning or evening, consistency is the key to successful treatment. Talk to your doctor or pharmacist.

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While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Gl-3, Building No.17,Unit-3, Ektha Society, Ghansoli, Navi Mumbai-400 701.
Other Info - MET2970
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