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compositionComposition:METHIMAZOLE-10MG
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Prescription Medicine
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Methimercazole 10 Tablet is used to treat an overactive thyroid (hyperthyroidism) and Graves disease. It contains methimazole, which works by reducing the excessive production of thyroid hormones. In some cases, this medicine may cause side effects such as headache, stomach upset, nausea, vomiting, mild skin rash or itching. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METHIMAZOLE-10MG

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Methimercazole 10 Tablet

Methimercazole 10 Tablet is an oral prescription medication used to treat hyperthyroidism, a condition where the thyroid gland produces too much thyroid hormone. It is also commonly prescribed to manage symptoms before thyroid surgery or radioactive iodine treatment. By regulating thyroid activity, Methimercazole 10 Tablet helps bring your body's metabolism back into a healthy balance.

To get the best results, it is important to take Methimercazole 10 Tablet consistently at the same time every day. You can take this tablet with or without food, but choosing one way and sticking to it helps keep the medicine levels steady in your body. Along with taking your medicine, reducing your intake of iodine-rich foods can support your treatment.

While taking Methimercazole 10 Tablet , some people may experience mild side effects like upset stomach, joint pain, or minor skin rashes. However, you must contact your doctor immediately if you develop serious symptoms such as a sore throat, fever, unusual bruising, or yellowing of your skin and eyes.

Do not take Methimercazole 10 Tablet if you have had a severe allergic reaction to antithyroid medications in the past. Before starting Methimercazole 10 Tablet , tell your doctor if you have liver disease, blood disorders, or a compromised immune system.

Methimercazole 10 Tablet can interact with blood thinners and certain heart medications, which may require your doctor to adjust your therapy. If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider, as special precautions are needed to protect your baby.

Uses of Methimercazole 10 Tablet

Methimercazole 10 Tablet used in the treatment of Hyperthyroidism and Graves' disease. The detailed uses of Methimercazole 10 Tablet are as follows:

  • Hyperthyroidism: Methimercazole 10 Tablet helps control an overactive thyroid gland by reducing the excess production of thyroid hormones.
  • Graves' disease: It manages the symptoms of this autoimmune disorder by stopping the thyroid from overproducing hormones.
  • Pre-surgery preparation: Taking Methimercazole 10 Tablet before a thyroidectomy (surgical removal of the thyroid) helps stabilize thyroid levels, making the procedure safer.
  • Radioactive iodine therapy preparation: It helps control thyroid hormone levels before or sometimes after undergoing radioactive iodine treatment.

Key Benefits

Methimercazole 10 Tablet helps manage an overactive thyroid by reducing the production of excess thyroid hormones. As thyroid hormone levels return to a healthier range, it helps improve symptoms and supports overall well-being. Benefits may include:

  • Helps reduce symptoms such as rapid heartbeat, hand tremors, excessive sweating, and heat intolerance.
  • Supports the maintenance of healthy thyroid hormone levels.
  • Helps relieve anxiety, irritability, and restlessness associated with hyperthyroidism.
  • Improves muscle strength and helps reduce fatigue.
  • Helps prevent unintended weight loss caused by an overactive thyroid.
  • Supports long-term control of hyperthyroidism and improves overall quality of life.

Directions for Use

  • Methimercazole 10 Tablet can be taken with or without food, as advised by your doctor.
  • It is usually taken 3 times daily or as prescribed by your doctor.
  • Swallow Methimercazole 10 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Methimercazole 10 Tablet Works

Methimercazole 10 Tablet contains Methimazole, which helps reduce the production of excess thyroid hormones by blocking their formation in the thyroid gland. This helps control symptoms of an overactive thyroid, such as rapid heartbeat, nervousness, sweating, weight loss, and tremors. Since it does not affect hormones already present in the body, it may take several weeks to show its full effect.
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Alcohol

Consult your doctor

Please consult your doctor before using Methimercazole 10 Tablet regarding the intake of alcohol during treatment. However, it is advised to limit alcohol consumption until your course is finished.

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Pregnancy

Consult your doctor

Methimercazole 10 Tablet is not recommended for use during the first trimester or three months of pregnancy since it can cause harmful effects on the foetus. It is advised to consult your doctor if you plan to conceive or are already pregnant before starting Methimercazole 10 Tablet .

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Breast Feeding

Caution

Methimercazole 10 Tablet passes into the breast milk when used by a lactating mother. Please consult your doctor before taking Methimercazole 10 Tablet if you are breastfeeding. Caution is recommended.

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Driving

Caution

Methimercazole 10 Tablet may make you feel dizzy and sleepy, which could affect your ability to drive or operate machines. Please do not drive or operate machines until you feel better.

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Liver

Consult your doctor

Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing Methimercazole 10 Tablet . Regular monitoring of liver function tests is advised during course.

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Kidney

Consult your doctor

Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing Methimercazole 10 Tablet .

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Children

Caution

Your doctor will decide the dose and duration based on your child’s age and medical condition.

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Heart

Caution

Methimercazole 10 Tablet should be taken with caution in patients with heart problems. Please inform your doctor if you have any pre-existing heart problems before using Methimercazole 10 Tablet .

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Geriatrics

Caution

Methimercazole 10 Tablet should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform a healthcare professional before use.

What if I have taken an overdose of Methimercazole 10 Tablet

If you or someone else takes too much Methimercazole 10 Tablet , seek immediate medical attention or contact a poison control center. Symptoms of an overdose may include skin swelling, fever, joint pain, or extreme fatigue.

Diet & Lifestyle Advise

  • Limit iodine-rich foods: High amounts of iodine from foods like kelp, seaweed, iodized salt, and certain seafood can interfere with your treatment. Talk to your doctor before using iodine-containing supplements.
  • Avoid heavy caffeine intake: Since hyperthyroidism can cause a racing heart and anxiety, limiting coffee, energy drinks, and sodas can help manage these symptoms.
  • Eat calcium-rich foods: An overactive thyroid can weaken your bones over time. Incorporating calcium and vitamin D into your diet supports bone health.
  • Get regular, low-impact exercise: Gentle physical activities like walking or swimming can help strengthen muscles and maintain bone density without overworking your heart.
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How Soon It Starts Working

  • The time required for Methimercazole 10 Tablet to start to work: Methimercazole 10 Tablet ideally shows its action within 12 to 18 hours after administration.
  • The time for which the effects of Methimercazole 10 Tablet last: The effect of Methimercazole 10 Tablet lasts for 36 to 72 hours.

What if you forget to take Methimercazole 10 Tablet

Take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and return to your regular routine. Do not take a double dose to make up for a missed one.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Monitor for signs of infection: A sudden fever or sore throat can be a sign of a rare but serious drop in white blood cells. Stop taking the medicine and contact your doctor immediately if this happens.
  • Watch for liver warning signs: Contact your doctor right away if you notice dark urine, pale stools, or yellowing of your skin or eyes.
  • Be consistent: Taking Methimercazole 10 Tablet at the exact same time every day helps maintain stable thyroid levels and improves the success of your treatment.
  • Inform all healthcare providers: Always tell your dentist, surgeon, or any other doctor that you are taking Methimercazole 10 Tablet before undergoing any medical procedures.
  • Keep up with blood work: Frequent thyroid and liver function blood tests are necessary to ensure the medication is working safely. Do not skip these appointments.

Drug-Drug Interactions

verifiedApollotooltip
  • Blood thinners (e.g., warfarin): Taking these medicines alongside Methimercazole 10 Tablet may affect how blood thinners work, increasing the risk of bleeding or reducing their effectiveness. Your doctor may monitor your treatment more closely.
  • Beta-blockers (e.g., metoprolol, propranolol): As thyroid hormone levels return to normal during treatment with Methimercazole 10 Tablet , your response to beta-blockers may change, and dose adjustments may be needed.
  • Heart medicine (e.g., digoxin): Treatment with Methimercazole 10 Tablet may change how your body responds to digoxin as hyperthyroidism improves, and your doctor may need to adjust the dose.
MethimazoleDeferiprone
Severe
MethimazolePropylthiouracil
Severe

Drug-Drug Interactions

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MethimazoleDeferiprone
Severe
How does the drug interact with Methimercazole 10 Tablet:
Taking Methimercazole 10 Tablet with Deferiprone may increase the risk of severe infections.

How to manage the interaction:
Taking Methimercazole 10 Tablet with Deferiprone together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms - like fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, pain, or burning during urination - contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MethimazolePropylthiouracil
Severe
How does the drug interact with Methimercazole 10 Tablet:
Taking Propylthiouracil with Methimercazole 10 Tablet can increase the risk of side effects.

How to manage the interaction:
Co-administration of Propylthiouracil with Methimercazole 10 Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without consulting a doctor.
MethimazoleMipomersen
Severe
How does the drug interact with Methimercazole 10 Tablet:
The combined use of Mipomersen and Methimercazole 10 Tablet together can increase the liver problems.

How to manage the interaction:
Although there is a possible interaction between Methimercazole 10 Tablet and Mipomersen, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, contact a doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, bleeding, pain, dark urine, or liver damage. Do not stop using any medications without talking to a doctor.
MethimazoleTeriflunomide
Severe
How does the drug interact with Methimercazole 10 Tablet:
The combined use of Methimercazole 10 Tablet with Teriflunomide can increase the risk of liver problems.

How to manage the interaction:
Taking Methimercazole 10 Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-coloured urine, liver damage, or bleeding. Do not discontinue any medications without consulting a doctor.
MethimazoleLomitapide
Severe
How does the drug interact with Methimercazole 10 Tablet:
Taking Lomitapide and Methimercazole 10 Tablet together can increase the risk of liver problems.

How to manage the interaction:
Although taking Methimercazole 10 Tablet and Lomitapide together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, contact a doctor immediately: fever, chills, joint pain, swelling, bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, bleeding, dark urine, or liver damage. Do not stop using any medications without a doctor's advice.
MethimazoleClozapine
Severe
How does the drug interact with Methimercazole 10 Tablet:
When Clozapine is taken with Methimercazole 10 Tablet, the effects of Clozapine increases.

How to manage the interaction:
There may be a possibility of interaction between Methimercazole 10 Tablet and Clozapine, but it can be taken if prescribed by a doctor. If you have any of these symptoms - feeling weak, having a sore throat, fever, mouth sores, feeling tired or having flu-like symptoms, contact a doctor right away. Do not stop using any medications without a doctor's advice.
MethimazoleFluphenazine
Severe
How does the drug interact with Methimercazole 10 Tablet:
Co-administration of Fluphenazine and Methimercazole 10 Tablet together can cause the risk of neutropenia leading to serious infections.

How to manage the interaction:
Although there is a possible interaction between Methimercazole 10 Tablet and Fluphenazine, you can take these medicines together if prescribed by a doctor. If you notice any of these signs - fever, chills, body aches, sore throat, coughing, breathing difficulties, mouth ulcers, or flu-like symptoms - contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Iodine-rich foods and supplements (e.g., seaweed, kelp, iodine supplements): Consuming large amounts of iodine may reduce the effectiveness of Methimercazole 10 Tablet by providing the thyroid gland with more iodine to produce thyroid hormones.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Methimercazole 10 Tablet is used to treat hyperthyroidism (an overactive thyroid) and Graves disease (an autoimmune disorder).
Methimercazole 10 Tablet consists of Methimazole, an anti-thyroid agent. It treats overactive thyroid (hyperthyroidism) and Graves disease by inhibiting the synthesis of thyroid hormones by the thyroid gland. Thus, Methimercazole 10 Tablet effectively helps in treating hyperthyroidism and relieving its symptoms.
Methimercazole 10 Tablet should be used with caution and only under doctor's supervision if you have a medical history of liver or kidney diseases, congenital disorders (birth defects), hypothyroidism (low levels of thyroid hormones), blood disorders like agranulocytosis (lowered white blood cell count) and thrombocytopenia (low levels of platelets) and pancreatitis (inflammation of the pancreas, an organ behind the stomach).
Sometimes, Methimercazole 10 Tablet may cause hypoprothrombinemia (deficiency of the blood-clotting substance, prothrombin) and lead to bleeding. Hence, your doctor may advise a test for prothrombin time before surgery while undergoing treatment with Methimercazole 10 Tablet . Please seek medical advice for more information.
It is advised to regularly monitor your thyroid hormone levels with thyroid function tests while using Methimercazole 10 Tablet . If there is clinical evidence of rising serum thyroid levels, your doctor may lower the dose of Methimercazole 10 Tablet .
If you missed a dose, take Methimercazole 10 Tablet as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
You may begin to feel better within 2 to 4 weeks of starting the medication, but it can take several months to fully restore your thyroid levels to normal. Talk to your doctor if you do not notice any improvement after a few weeks.
Methimercazole 10 Tablet is generally not recommended during the first trimester of pregnancy due to potential risks to the developing baby, though it may be used later in pregnancy if necessary. Talk to your doctor about the safest options for managing your thyroid during pregnancy.
Yes, you will need frequent blood tests to monitor your thyroid hormone levels, liver enzymes, and blood cell counts. These tests help your doctor adjust your dose and ensure the medicine is working safely. Talk to your doctor about your testing schedule.
As Methimercazole 10 Tablet successfully slows down your overactive metabolism, your body may return to its normal weight, which some patients experience as weight gain. This is typically a sign that your thyroid is recovering. Talk to your doctor or a dietitian if you have concerns about weight changes.

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Country of origin

India

Manufacturer/Marketer address

16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India
Other Info - MET1768
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