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compositionComposition:METHENAMINE HIPPURATE-1GM
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Prescription Medicine
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Methaclear 1 gm Tablet 10's is used to treat recurrent urinary tract infections (UTIs). It is also used to prevent urinary tract infections in individuals with bladder catheters and in those undergoing specific medical procedures. It works by releasing formaldehyde in acidic urine, which acts as a bactericidal agent against common bacteria that cause UTIs. Possible side effects may include rashes, itching, stomach irritation, bladder irritation (causes burning and pain during urination), nausea and vomiting.

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Written By ,
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

METHENAMINE HIPPURATE-1GM

Manufacturer/Marketer :

Dr Reddy's Laboratories Ltd

Consume Type :

Oral

Expires on or after :

Jan-28

Return Policy :

Not Returnable

About Methaclear 1 gm Tablet 10's

Methaclear 1 gm Tablet 10's is an oral medicine used to prevent or suppress recurrent urinary tract infections (UTIs). It is prescribed for individuals who experience frequent bladder or kidney infections to help keep the urinary tract free of harmful bacteria over the long term. This medicine is not used to treat an active, sharp UTI, but rather to stop future infections from coming back.

To work effectively, Methaclear 1 gm Tablet 10's must be taken regularly and consistently as directed by your healthcare provider. You can take this medicine with or without food, though taking it with meals can help prevent a mild upset stomach. Keeping your urine acidic is key to this medicine's success, so incorporating dietary habits that lower urine pH can support your treatment results.

While taking Methaclear 1 gm Tablet 10's, some people may experience mild side effects, such as nausea, stomach upset, or a mild skin rash. If you experience serious side effects, such as painful urination, blood in your urine, or signs of a severe allergic reaction, stop taking the medication and consult your doctor immediately.

Before starting this medicine, talk to your doctor if you have severe kidney disease, liver damage, or severe dehydration. Do not take this if you have severe kidney failure, as your body will not be able to clear the medicine safely.

This medicine can interact with certain other treatments, such as medications that make your urine less acidic. If you are pregnant, breastfeeding, or are an older adult, talk to your doctor or pharmacist to ensure this medicine is appropriate and safe for your specific situation.

Uses of Methaclear 1 gm Tablet 10's

Methaclear 1 gm Tablet 10's is a urinary antiseptic used to help prevent certain recurrent urinary tract infections. Its detailed uses include:

  • Recurrent urinary tract infections (UTIs): Methaclear 1 gm Tablet 10's helps prevent the recurrence of certain chronic bladder or urinary tract infections by releasing a substance that can inhibit bacterial growth in acidic urine.
  • Long-term urinary suppression: It may help reduce the risk of repeated urinary infections in people who are prone to them because of certain urinary tract conditions or long-term catheter use, when prescribed by a doctor.

Key Benefits

Methaclear 1 gm Tablet 10's helps prevent recurrent urinary tract infections and supports long-term urinary health when used as prescribed. Its benefits include:

  • Helps prevent certain recurrent urinary tract infections by limiting the growth of bacteria in the urinary tract, which may reduce repeated episodes of discomfort and disruption.
  • Provides a preventive treatment option for people who are prone to recurring urinary infections and need long-term protection.
  • Unlike conventional antibiotics, Methaclear 1 gm Tablet 10's works mainly in the urinary tract and does not directly kill bacteria throughout the body, which may result in less pressure for antibiotic resistance when used appropriately.
  • May be suitable for prolonged preventive treatment in selected patients, as determined by a doctor.

Directions for Use

  • Methaclear 1 gm Tablet 10's can be taken with or without food as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Methaclear 1 gm Tablet 10's as a whole with a glass of water.
  • If you find it hard to swallow the tablets, you may crush them and take them with milk or fruit juice.

How Methaclear 1 gm Tablet 10's Works

Once you take Methaclear 1 gm Tablet 10's, it is absorbed into your bloodstream and filtered by your kidneys directly into your urine. When it reaches your bladder, the acidic environment of your urine causes the medicine to break down into formaldehyde. Formaldehyde acts as a local sanitizing agent, killing the bacteria in your urinary tract and preventing them from sticking to the bladder walls. Because this conversion only happens in acidic urine, the medicine targets bacteria exactly where it is needed without affecting other systems in your body.
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Alcohol

Consult your doctor

It is not known if you can consume alcohol while using Methaclear 1 gm Tablet 10's. Please consult your doctor for more information.

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Pregnancy

Consult your doctor

If you are pregnant, inform your doctor before taking Methaclear 1 gm Tablet 10's. Your doctor will recommend this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known whether Methaclear 1 gm Tablet 10's passes into breastmilk. Please consult your doctor if you are breastfeeding before using this medicine. Your doctor will prescribe this medicine if the benefits outweigh the risks.

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Driving

Safe

It is considered safe to drive or engage in activities that require mental alertness, as this medicine does not affect cognitive abilities. Please consult your doctor if you have concerns.

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Liver

Caution

Methaclear 1 gm Tablet 10's is not recommended for use in patients with severe liver disease. If you have a pre-existing liver disease or a history of liver disease, inform your doctor before taking this medicine.

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Kidney

Caution

If you have kidney disease, inform your doctor before taking Methaclear 1 gm Tablet 10's.

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Children

Consult your doctor

Methaclear 1 gm Tablet 10's is not recommended for children under the age of 6, as its safety and efficacy have not been established.

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Heart

Consult your doctor

Inform your doctor if you have any heart problems before using Methaclear 1 gm Tablet 10's.

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Geriatrics

Caution

Methaclear 1 gm Tablet 10's should be used with caution in elderly patients. The dose may be adjusted by the doctor based on the patient's health condition.

What if I have taken an overdose of Methaclear 1 gm Tablet 10's

If you suspect an overdose or experience severe symptoms like blood in the urine or extreme stomach pain, seek immediate medical attention or contact your local poison control center right away.

Diet & Lifestyle Advise

  • Keep your urine acidic: Since this medicine requires acidic urine to work, consider drinking unsweetened cranberry juice or taking vitamin C supplements, as recommended by your doctor.
  • Limit alkaline-producing foods: Avoid eating large quantities of citrus fruits, milk, dairy products, or antacids containing sodium bicarbonate, as these can make your urine less acidic and reduce the medicine's effectiveness.
  • Stay hydrated: Drink moderate, consistent amounts of water throughout the day to keep your urinary tract clean, but avoid excessive fluids that might dilute the medicine too much.
  • Practice proper hygiene: Always wipe from front to back after using the restroom to prevent bacteria from entering your urinary tract, and empty your bladder fully whenever you feel the urge.
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How Soon It Starts Working

The time required for Methaclear 1 gm Tablet 10's to start to work: Methaclear 1 gm Tablet 10's ideally shows its action within 30 minutes after administration. The time for which the effects of Methaclear 1 gm Tablet 10's last: The duration of action for Methaclear 1 gm Tablet 10's is not clinically established.

What if you forget to take Methaclear 1 gm Tablet 10's

If you miss a dose, take it as soon as you remember. If it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Methaclear 1 gm Tablet 10's tablets at room temperature, strictly between 68°F and 77°F (20°C to 25°C).

Drug Warnings

  • Monitor your urine acidity: Your doctor may ask you to use home pH test strips to check your urine acidity regularly to ensure the medicine remains active.
  • Avoid sulfa drugs: Do not take sulfonamide (sulfa) antibiotics while using Methaclear 1 gm Tablet 10's, as they can react with this medicine and form solid crystals in your urinary tract.
  • Watch for new symptoms: Contact your doctor if you experience a fever, chills, or sudden lower back pain, as these are signs of an active infection that may require a different antibiotic.
  • Routine health checks: Your doctor may occasionally order blood or urine tests to monitor your liver and kidney health if you are using this medicine long-term.

Drug-Drug Interactions

verifiedApollotooltip
  • Sulfonamides (sulfa antibiotics): Combining these with Methaclear 1 gm Tablet 10's can lead to the formation of crystals in your urine, which may damage your kidneys.
  • Urinary alkalinizers: Medicines like sodium bicarbonate (baking soda), potassium citrate, or carbonic anhydrase inhibitors can make your urine alkaline, stopping Methaclear 1 gm Tablet 10's from working.
MethenamineAcetazolamide
Severe

Drug-Drug Interactions

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MethenamineAcetazolamide
Severe
How does the drug interact with Methaclear 1 gm Tablet:
Co-administration of Acetazolamide may reduce the effectiveness of Methaclear 1 gm Tablet.

How to manage the interaction:
Although there is a possible interaction between Acetazolamide and Methaclear 1 gm Tablet, you can take these medicines together if prescribed by a doctor. However, frequent urine pH testing may be recommended. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alkalizing foods and beverages: Consuming large amounts of milk, dairy products, or citrus fruits and juices can raise your urine pH, reducing the effectiveness of this medicine.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTIBIOTICS]

FAQs

Methaclear 1 gm Tablet 10's is used to treat recurrent urinary tract infections (UTIs). It is also used to prevent urinary tract infections in individuals with bladder catheters and in those undergoing specific medical procedures.
Methaclear 1 gm Tablet 10's contains Methenamine hippurate, which releases formaldehyde in acidic urine to help kill bacteria. Hippuric acid supports this by maintaining urine acidity and has mild antibacterial properties. This combination is effective against bacteria such as E. coli, enterococci, and staphylococci, but may be less effective against resistant strains like Enterobacter aerogenes.
UTI is commonly caused by an abnormal rise in the normal concentrations of tract flora, namely a bacterium called E. coli. It is common in females due to the shorter length of the urethra.
Do not stop taking Methaclear 1 gm Tablet 10's without consulting your doctor, as it may reduce the medication’s effectiveness. To treat your condition effectively, continue taking Methaclear 1 gm Tablet 10's for as long as prescribed by your doctor.
Yes, Methaclear 1 gm Tablet 10's is intended for daily use as prescribed by your doctor. Follow the recommended dosage carefully and do not skip or exceed it without medical guidance.
If you miss a dose, try to take it as soon as you remember. However, if it is time for the scheduled dose, skip the missed dose and take the scheduled dose instead. Avoid taking the double dose as it may lead to an overdose or unpleasant side effects.
Taking higher doses than prescribed is ineffective and may cause side effects. Therefore, it's essential to follow the dosage instructions provided by your doctor to ensure safe and effective use.
Common side effects include rashes, itching, stomach irritation, bladder irritation causes burning and pain during urination, nausea and vomiting. Seek medical care if the symptoms persist or worsen.
No, Methaclear 1 gm Tablet 10's is strictly used to prevent or suppress recurrent infections. If you have active symptoms of a UTI, your doctor will prescribe a standard antibiotic to clear the infection first before you begin taking Methaclear 1 gm Tablet 10's. Talk to your doctor if you suspect an active infection.
Yes, cranberry juice helps maintain acidic urine, which is essential for this medicine to convert into its active form. However, avoid drinking excessive amounts of fluids so you do not dilute the medicine in your bladder. Talk to your doctor or pharmacist about a healthy fluid balance.
If you are pregnant or breastfeeding, you must consult your healthcare provider before taking this medicine. They will evaluate the benefits and risks to ensure the safety of you and your baby. Talk to your doctor for personalized advice.
This medicine is typically prescribed for long-term use, often lasting several months, to prevent recurrent infections. Your doctor will determine the exact duration based on your medical history. Talk to your doctor before stopping the medicine.
Many antacids contain sodium bicarbonate, which makes your urine less acidic and prevents Methaclear 1 gm Tablet 10's from working. You should avoid these antacids; ask your pharmacist to recommend a safe alternative for heartburn. Talk to your doctor or pharmacist before starting any new over-the-counter medicine.
No, Methaclear 1 gm Tablet 10's does not typically change your urine color. If you notice your urine is pink, red, or dark, this could indicate blood or an infection, and you should seek medical advice. Talk to your doctor if you notice any unusual urine changes.
There is no direct interaction between alcohol and Methaclear 1 gm Tablet 10's, but alcohol can irritate your bladder and cause dehydration, which may worsen urinary tract symptoms. It is best to limit alcohol during your treatment. Talk to your doctor or pharmacist for more information.
Because Methaclear 1 gm Tablet 10's converts to formaldehyde in the bladder—which physically destroys bacteria rather than targeting their biological processes—it is highly unlikely to cause bacterial resistance. This makes it suitable for long-term prevention. Talk to your doctor if you have concerns about antibiotic resistance.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Dr. Reddy'S Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, India.
Other Info - MET2886
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