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  3. Metfine XL-25 Tablet 10's

Metfine XL-25 Tablet 10's, Pack of 10 TABLETS
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Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Metfine XL-25 Tablet belongs to the class of antihypertensive medicines used in the treatment of high blood pressure. This medicine also helps reduce the chances of heart problems such as heart attack and stroke. This medicine suppresses the contraction of blood vessels and promotes smooth blood flow. It also alters the response to nerve impulses in the heart, thereby making the heart pump blood more easily. Common side effects include dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache.

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Composition :

METOPROLOL SUCCINATE-25MG

Manufacturer/Marketer :

Finecure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Metfine XL-25 Tablet

Metfine XL-25 Tablet is used in the treatment of high blood pressure (hypertension), heart-related chest pain (angina), and irregular heart rhythm (arrhythmia). Hypertension is a lifelong or chronic condition in which the force exerted by the blood against the artery walls becomes so high that it leads to heart disease.

Metfine XL-25 Tablet contains Metoprolol Succinate, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body.

Not everyone who is taking Metfine XL-25 Tablet will get these side effects. In some cases, Metfine XL-25 Tablet may cause certain common side effects like dizziness, tiredness, diarrhoea, stomach pain, nausea, and headache. Most of these side effects do not require medical attention and resolve gradually over time. However, if the side effects are persistent, reach out to your doctor.

You can take Metfine XL-25 Tablet with food or without food. It should be swallowed as a whole with a glass of water. Do not chew, bite, crush, or break it. Your doctor will advise you on how often you should take your tablets based on your medical condition. It is always important to complete your treatment course for better results.

Inform your doctor if you are allergic to Metfine XL-25 Tablet . Also, let your doctor know if you have low blood pressure, asthma, an overactive thyroid, metabolic acidosis, or severe blood circulation problems. Consult your doctor before taking Metfine XL-25 Tablet if you are pregnant or breastfeeding. Metfine XL-25 Tablet is not recommended for use in children. Metfine XL-25 Tablet may cause dizziness, so drive with caution.

Uses of Metfine XL-25 Tablet

Metfine XL-25 Tablet is used in the treatment of High blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction). The detailed uses of Metfine XL-25 Tablet are as follows:

  • Treatment of Hypertension: Metfine XL-25 Tablet controls high blood pressure by reducing the heart rate and the force of contraction, thereby lowering blood pressure.
  • Prevention of Heart-related Chest Pain: Metfine XL-25 Tablet prevents chest pain (angina) by reducing the workload on the heart and improving blood flow to the heart muscle.
  • Control of Abnormal Heart Rhythms: Metfine XL-25 Tablet helps manage irregular heartbeats (arrhythmias) by slowing the heart rate and stabilizing the heart's rhythm, reducing symptoms and improving heart function.
  • Management of Heart Attack: Metfine XL-25 Tablet is used to manage heart attack (myocardial infarction) by reducing the workload on the heart and preventing further damage.

Directions for Use

  • Metfine XL-25 Tablet can be taken with or without food, or as advised by your doctor.
  • Generally, it is recommended to be taken once daily. Follow your doctor's instructions regarding dosage and timing for optimal results.
  • Swallow Metfine XL-25 Tablet as a whole with a glass of water.
  • Do not crush, chew, or break it.

Medicinal Benefits

  • Metfine XL-25 Tablet  helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body.
  • This medicine lowers the blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.
  • Metfine XL-25 Tablet may also help in relieving symptoms of migraine-related headache and tremors (fits).

How Metfine XL-25 Tablet Works

Metfine XL-25 Tablet contains Metoprolol succinate, which helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. This lowers blood pressure and helps in reducing the risk of having a stroke, heart attack, or other heart or kidney problems in the future.

Storage

• Store in a cool and dry place away from sunlight. • Keep Metfine XL-25 Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Metfine XL-25 Tablet
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

What if I have taken an overdose of Metfine XL-25 Tablet

Do not take more than the prescribed dose. Overdose of Metfine XL-25 Tablet may cause nausea, vomiting, decreased consciousness or loss of consciousness (coma), irregular, fast, or slow heartbeat, chest pain, dizziness, fatigue or weakness and fainting. Seek immediate medical help if you suspect that you might have taken an overdose of Metfine XL-25 Tablet .

Drug Warnings

  • Do not take Metfine XL-25 Tablet if you are allergic to any component present in Metfine XL-25 Tablet or any other beta-blockers.
  • Avoid taking Metfine XL-25 Tablet if you have/had heart conduction, rhythm problems, uncontrolled/severe heart failure, blocked blood vessels, blood circulation problems, untreated pheochromocytoma, metabolic acidosis, low blood pressure, or Prinzmetal angina.
  • Inform your doctor if you have asthma, COPD, diabetes, blood vessel disorder, slow heart rate, pheochromocytoma, myasthenia gravis, dry eye problems, kidney or liver impairment; if you are taking anti-depressants, other blood pressure-lowering medicines, or anti-arrhythmic agents.
  • Consult your doctor before taking Metfine XL-25 Tablet if you are pregnant or breastfeeding.
  • Metfine XL-25 Tablet is not recommended for children as safety and efficacy have not been established.
  • Metfine XL-25 Tablet may cause dizziness, so drive with caution.
  • Don't stop taking Metfine XL-25 Tablet without consulting your doctor. Suddenly stopping the use of Metfine XL-25 Tablet may cause changes in your heart rhythm and blood pressure, cause chest pain, or a heart attack. Your doctor will gradually lower your dose to help prevent these symptoms.

Drug-Drug Interactions

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MetoprololSaquinavir
Severe
MetoprololAcebutolol
Severe

Drug-Drug Interactions

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MetoprololSaquinavir
Severe
How does the drug interact with Metfine XL-25 Tablet:
Using Metfine XL-25 Tablet and Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possible interaction between Metfine XL-25 Tablet and Saquinavir, but they can be taken together if your doctor has prescribed them. However, consult a doctor immediately if you experience dizziness, lightheadedness, fainting, slow pulse, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololAcebutolol
Severe
How does the drug interact with Metfine XL-25 Tablet:
Coadministration of Acebutolol with Metfine XL-25 Tablet can cause abnormal heart rhythm.

How to manage the interaction:
Taking Metfine XL-25 Tablet and Acebutolol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololElvitegravir
Severe
How does the drug interact with Metfine XL-25 Tablet:
Taking elvitegravir may increase the metabolism of Metfine XL-25 Tablet.

How to manage the interaction:
Although there may be an interaction, Metfine XL-25 Tablet can be taken with Elvitegravir if prescribed by the doctor. Consult the doctor if you experience dizziness, palpitations, fainting, slow or fast pulse, or irregular heartbeats. Do not discontinue any medications without talking to your doctor.
MetoprololTizanidine
Severe
How does the drug interact with Metfine XL-25 Tablet:
Coadministration of Metfine XL-25 Tablet and Tizanidine may reduce the efficiency of Metfine XL-25 Tablet.

How to manage the interaction:
Taking Metfine XL-25 Tablet and Tizanidine together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience blurry vision, confusion, dizziness, fainting, lightheadedness, nausea or vomiting, contact your doctor immediately. do not discontinue any medications without talking to your doctor.
MetoprololClonidine
Severe
How does the drug interact with Metfine XL-25 Tablet:
Co-administration of Clonidine and Metfine XL-25 Tablet may lower blood pressure and slow the heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Metfine XL-25 Tablet, you can take these medicines together if prescribed by your doctor. However, if you experience headaches, slow heartbeat, dizziness, or feeling like you might pass out, contact your doctor. Do not stop using any medications without first talking to your doctor.
MetoprololCeritinib
Severe
How does the drug interact with Metfine XL-25 Tablet:
Taking ceritinib together with Metfine XL-25 Tablet can slow your heart rate and increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Metfine XL-25 Tablet and Ceritinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any dizziness, lightheadedness, fainting, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololVerapamil
Severe
How does the drug interact with Metfine XL-25 Tablet:
Coadministration of Metfine XL-25 Tablet with Verapamil may lead to increased side effects.

How to manage the interaction:
Although there may be an interaction, Metfine XL-25 Tablet can be taken with Verapamil if prescribed by the doctor. Consult a prescriber if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
MetoprololDiltiazem
Severe
How does the drug interact with Metfine XL-25 Tablet:
Coadministration of Metfine XL-25 Tablet with Diltiazem can increase the side effects.

How to manage the interaction:
Although there is a possible interaction between Metfine XL-25 Tablet and Diltiazem, you can take these medicines together if prescribed by your doctor. Consult your doctor immediately if you experience fatigue, headache, fainting, swelling of the extremities, weight gain, shortness of breath, chest pain, increased or decreased heartbeat, or irregular heartbeat. Do not discontinue any medications without consulting a doctor.
MetoprololAminophylline
Severe
How does the drug interact with Metfine XL-25 Tablet:
Coadministration of Aminophylline with Metfine XL-25 Tablet together can make Metfine XL-25 Tablet less effective and increase the effects of aminophylline.

How to manage the interaction:
Taking Aminophylline with Metfine XL-25 Tablet may lead to an interaction, it can be taken only if a doctor has advised it. If you experience nausea, vomiting, sleeplessness, restlessness, irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
MetoprololAtazanavir
Severe
How does the drug interact with Metfine XL-25 Tablet:
Use of Metfine XL-25 Tablet with Atazanavir may increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there may be an interaction between Metfine XL-25 Tablet and Atazanavir, it can be taken if prescribed by the doctor. Consult the doctor if you experience dizziness, lightheadedness, fainting, or irregular heartbeat, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Maintain a healthy body weight, ideally with a BMI between 18.5 and 24.9, as excess weight increases the risk of high blood pressure and heart disease.
  • Engage in regular physical activity, aiming for at least 150 minutes of moderate-intensity exercise per week (e.g., brisk walking, cycling, swimming) to help lower blood pressure by about 5–8 mmHg.
  • Limit sodium intake to ≤2300 mg per day, with an ideal goal of 1500 mg daily for adults with high blood pressure or heart problems.
  • If you drink alcohol, limit intake to up to 1 drink per day for women and up to 2 drinks per day for men, as excessive drinking can raise blood pressure.
  • Quit smoking, as it significantly increases the risk of heart attack, stroke, and complications from high blood pressure.
  • Manage stress through relaxation techniques, deep breathing, mindfulness, adequate sleep, and spending time with loved ones to help maintain stable blood pressure levels.
  • Monitor blood pressure regularly at home and keep a record. Contact your doctor promptly if you notice frequent or large fluctuations.
  • Eat a heart-healthy diet, rich in fruits, vegetables, whole grains, lean protein, and omega-3 fatty acids (from fish, flaxseeds, or walnuts) to support cardiovascular health.
  • Use healthy cooking oils such as olive, canola, or soybean oil, and limit saturated fats to help manage blood pressure and improve heart health.
  • Follow your doctor’s advice strictly regarding medications, diet, and lifestyle adjustments to reduce the risk of severe heart complications.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Metfine XL-25 Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Alcohol might increase the blood pressure-lowering effect of Metfine XL-25 Tablet . It might also cause increased dizziness. Therefore, avoid alcohol consumption while taking Metfine XL-25 Tablet .

bannner image

Pregnancy

Unsafe

Metfine XL-25 Tablet belongs to pregnancy category C. Metfine XL-25 Tablet is not recommended for use during pregnancy. If you are pregnant, think you are pregnant or planning for pregnancy, consult your doctor.

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Breast Feeding

Caution

Metfine XL-25 Tablet may pass into breastmilk. Consult a doctor before taking Metfine XL-25 Tablet if you are breastfeeding.

bannner image

Driving

Caution

Metfine XL-25 Tablet may cause dizziness and tiredness. Therefore, drive or operate machinery only if you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed. Consult your doctor before taking Metfine XL-25 Tablet if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed. Consult your doctor before taking Metfine XL-25 Tablet if you have kidney impairment or any concerns regarding this.

bannner image

Children

Unsafe

Metfine XL-25 Tablet is not recommended in children as the safety and efficacy have not been established.

Have a query?

FAQs

Metfine XL-25 Tablet is used to treat high blood pressure (hypertension), prevention of heart-related chest pain (angina), heart rhythm disorder (arrhythmia), and heart attack (myocardial infarction).

Metfine XL-25 Tablet helps in slowing down the heart rate, making it easier for the heart to pump blood throughout the body. Thereby, lowers blood pressure.

High blood pressure increases the workload on the arteries and heart. If untreated, it could damage the blood vessels of the heart, brain, kidney and might result in stroke, heart failure or kidney failure. Hypertension increases the risk of heart attacks. Therefore, anti-hypertensives such as Metfine XL-25 Tablet are used to lower the blood pressure to normal; this reduces the risk of developing these disorders.

Do not stop taking Metfine XL-25 Tablet without consulting your doctor, as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Metfine XL-25 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Metfine XL-25 Tablet .

Consult your doctor before taking Metfine XL-25 Tablet if you have hyperthyroidism (overactive thyroid) as it might mask the symptoms or make it difficult to recognise the signs of thyrotoxicosis (excess thyroid hormone in the body).

Consult your doctor before taking Metfine XL-25 Tablet with anti-diabetic medicines as it might mask the signs of low blood sugar. Regular monitoring of blood glucose levels while taking Metfine XL-25 Tablet is advised.

Your doctor may probably ask you to stop taking Metfine XL-25 Tablet 24hours prior to the surgery, as it might lower blood pressure when combined with general anaesthesia. If you are due to have any surgery or are receiving an anaesthetic, inform the doctor that you are taking Metfine XL-25 Tablet .

Taking Metfine XL-25 Tablet along with multivitamin/multimineral supplements may decrease the effect of Metfine XL-25 Tablet . Therefore, maintain a gap of at least 2hours between both. However, you are advised to take Metfine XL-25 Tablet with other medicines only after consulting your doctor.

Yes, Metfine XL-25 Tablet is a selective beta-blocker, that acts on the heart muscles.

No, do not stop taking Metfine XL-25 Tablet if your blood pressure level comes in control as discontinuing suddenly may worsen the condition. Therefore, continue taking Metfine XL-25 Tablet for long as it is advised by your doctor.

No, Metfine XL-25 Tablet is not a blood thinner. Metfine XL-25 Tablet relaxes the blood vessels, and slows down the heart rate. Thereby, it reduces the workload on the heart and makes it easier to pump blood effectively.

The time taken by Metfine XL-25 Tablet to start working varies from person to person. Usually, it starts working within 15 minutes. However, it may take up to 2 hours to start working in some people. The maximum or full effect is usually achieved within 1 week as it starts acting slowly. In case you do not feel any difference while taking Metfine XL-25 Tablet , do not worry. It exerts its beneficial effects when taken for a long time.

The side effects of Metfine XL-25 Tablet include stomach pain, nausea, diarrhoea, dizziness, tiredness or headache. If these side effects persist or worsen, please consult your doctor.

Metfine XL-25 Tablet is generally safe if used as prescribed by the doctor. If this medication is stopped suddenly, it may cause harmful effects such as a sudden increase in the heart rate and affect its activity, which can be dangerous for heart failure patients and in some cases even result in a heart attack. Therefore, take Metfine XL-25 Tablet for the prescribed duration and do not stop taking it suddenly.

Metfine XL-25 Tablet belongs to the class of medicines called beta-blockers. Though their effect on sleep differs from person to person, it has been found that these medications are known to change the sleep pattern and disturb sleep in some patients. On the other hand, it has also been observed to promote better sleep in patients with increased anxiety and heart rate by calming down the nerves and heart. If you have any sleep disturbances, please consult your doctor.

No, you are recommended to avoid alcohol consumption after taking Metfine XL-25 Tablet as alcohol might increase the blood pressure-lowering effect of Metfine XL-25 Tablet and might cause increased dizziness.

Country of origin

India

Manufacturer/Marketer address

A1201, Mondeal Heights,Near Novotel, Sarkhej - Gandhinagar Hwy, Ahmedabad, Gujarat 380015
Other Info - MET1824

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 5, 2025 | 8:51 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/metoprolol.html
  2. https://www.nhs.uk/medicines/metoprolol/
  3. https://www.medicines.org.uk/emc/files/pil.5816.pdf
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/019962s032lbl.pdf

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