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  3. Met XL AM 25/5 Tablet 20's

Prescription drug
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Met XL AM 25/5 Tablet 20's, Pack of 20 TABLETS
Met XL AM 25/5 Tablet 20's, Pack of 20 TABLETS
Met XL AM 25/5 Tablet 20's, Pack of 20 TABLETS
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Extra 15% Off with Bank Offers

Composition :

AMLODIPINE-5MG + METOPROLOL SUCCINATE-25MG

Manufacturer/Marketer :

Ajanta Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Met XL AM 25/5 Tablet

Met XL AM 25/5 Tablet is used to treat high blood pressure/hypertension and angina pectoris. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Angina is basically a pain in the heart and chest.

Met XL AM 25/5 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow.

In some cases, Met XL AM 25/5 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention. However, talk to your doctor if these side effects persist or worsen.

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Avoid consuming alcohol with Met XL AM 25/5 Tablet as there may be an interaction. Met XL AM 25/5 Tablet  may cause dizziness; therefore, drive only if you are alert.

Uses of Met XL AM 25/5 Tablet

Met XL AM 25/5 Tablet is used in the treatment of hypertension and angina pectoris. The detailed uses of Met XL AM 25/5 Tablet are as follows:

  • Treatment of Hypertension: Met XL AM 25/5 Tablet lowers blood pressure by relaxing blood vessels and slowing heart rate.
  • Management of Angina (Chest Pain): Met XL AM 25/5 Tablet improves blood flow to the heart, reducing pain and discomfort.
  • Support in Chronic Heart Failure: Met XL AM 25/5 Tablet reduces the workload on the heart and improves pumping efficiency.
  • Control of Abnormal Heart Rhythms: Met XL AM 25/5 Tablet helps regulate heartbeat and prevent arrhythmias.

Have a query?

Directions for Use

  • Take Met XL AM 25/5 Tablet with or without food or as advised by a doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication, to ensure the safety.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

  • Met XL AM 25/5 Tablet is a combination antihypertensive medication containing Metoprolol succinate and Amlodipine.
  • It is used primarily to treat hypertension and to relax the blood vessels for seamless flow of blood. 
  • Metoprolol succinate is a beta-blocker that eases the symptoms of hypertension by blocking catecholamines that lead to increased pressure and heart rate.
  • Amlodipine is a calcium channel blocker that decreases blood pressure by preventing the influx of calcium ions into cells and by enlarging and relaxing arteries.
  • In addition, Met XL AM 25/5 Tablet also reduces the oxygen demands of the heart, relaxing the heart and blood vessels and requiring the heart to do less work.

How Met XL AM 25/5 Tablet Works

Met XL AM 25/5 Tablet contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, Met XL AM 25/5 Tablet helps treat high blood pressure.

Storage

• Store in a cool and dry place away from sunlight. • Keep Met XL AM 25/5 Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Met XL AM 25/5 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Reduce salt intake to minimize fluid buildup.
  • Use compression stockings, sleeves, or gloves.
  • Gently massage the affected area towards the heart.
  • Protect the swollen area from injury and keep it clean.
  • Use lotion or cream to keep the skin moisturized.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
  • Avoid triggers like alcohol, caffeine, and energy drinks.
  • Try relaxation techniques such as yoga, meditation, or deep breathing.
  • Exercise regularly as it helps maintain heart health.
  • Follow a nutritious and balanced diet.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Managing depression as a side effect of medication: a comprehensive guide.
  • Remember, managing depression as a side effect of medication requires patience, persistence, and collaboration with your healthcare team.
  • Tell your doctor about your depression symptoms to adjust medication.
  • Consult a therapist or counsel for emotional support.
  • Engage in regular exercise to release endorphins (neurotransmitters).
  • Practice stress-reducing techniques like meditation and deep breathing.
  • Build a support network of friends, family, and support groups.
  • Establish a consistent sleep schedule.
  • Eat a nutritious diet rich in fruits, vegetables, and whole grains.
  • Limit or avoid alcohol and recreational substances.
  • Keep a mood journal to track symptoms and progress.

What if I have taken an overdose of Met XL AM 25/5 Tablet

Do not take more than the prescribed dose. Overdose of Met XL AM 25/5 Tablet may cause low blood pressure, slow pulse rate, shortness of breath, low blood sugar, dizziness, feeling sick and blue discolouration of the skin. Seek immediate medical attention if you suspect that you might have taken an overdose of this medicine.

Drug Warnings

  • Met XL AM 25/5 Tablet should not be used in case of any known allergy to either of the components. 
  • Met XL AM 25/5 Tablet should be used with caution in case of high risk or previous history of any arterial or thrombotic disorders, shock, cardiovascular health disorders, diabetes, heart failure, or any disease-causing psoriasis.
  • Please inform your doctor in case of any history of an overactive thyroid, asthma, phaeochromocytoma (high BP due to a tumour in the adrenal glands), myasthenia gravis (neuromuscular disorder), COPD, heart block, liver disease or renal disease.
  • Consult your doctor before using Met XL AM 25/5 Tablet during pregnancy or breastfeeding.
  • Keep your doctor informed in case you are waiting to undergo any surgery or dental procedure.
  • Met XL AM 25/5 Tablet may interact with alcohol; please consult your doctor before use.
  • Met XL AM 25/5 Tablet may cause dizziness, so drive or operate heavy machinery only if you are alert. 

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AmlodipineIdelalisib
Severe

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Met XL AM 25/5 Tablet:
Using Met XL AM 25/5 Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Met XL AM 25/5 Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AmlodipineIdelalisib
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Coadministration of Met XL AM 25/5 Tablet and Idelalisib may raise Met XL AM 25/5 Tablet levels in the blood this may lead to serious side effects (irregular heart rhythm, fluid retention, swelling, heart failure, and abnormally low blood pressure).

How to manage the interaction:
Although taking Met XL AM 25/5 Tablet with idelalisib can result in an interaction, it can be taken if a doctor has advised it. However, if you experience dizziness or fainting, sudden, unexplained weight gain, swelling of the hands, ankles, or feet, chest discomfort, or trouble breathing while taking these drugs, consult the doctor. Use caution while getting up from a sitting or sleeping position and avoid driving or using dangerous machinery. Do not stop using any medications without a doctor's advice.
AmlodipinePhenytoin
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using Met XL AM 25/5 Tablet and phenytoin together may drastically lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although Met XL AM 25/5 Tablet with phenytoin can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifapentine
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Coadministration of Met XL AM 25/5 Tablet and Rifapentine may significantly reduce the blood levels of Met XL AM 25/5 Tablet, which may make the medication less effective.

How to manage the interaction:
There may be a possibility of interaction between Met XL AM 25/5 Tablet and Rifapentine, but it can be taken if prescribed by a doctor. If you have any symptoms, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using Met XL AM 25/5 Tablet and primidone together may lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Met XL AM 25/5 Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineCarbamazepine
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Coadministration of Met XL AM 25/5 Tablet and carbamazepine together may significantly reduce Met XL AM 25/5 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Although there is an interaction between Met XL AM 25/5 Tablet with carbamazepine, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms contact the doctor immediately. Do not stop using any medications without talking to a doctor.
AmlodipineFosphenytoin
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
When Met XL AM 25/5 Tablet is taken with Fosphenytoin, it may decrease the blood levels of Met XL AM 25/5 Tablet, which may make Met XL AM 25/5 Tablet less effective.

How to manage the interaction:
Although taking Met XL AM 25/5 Tablet and Fosphenytoin together can cause an interaction, it can be taken if a doctor has suggested it. Do not stop using any medications without a doctor's advice.
AmlodipineSimvastatin
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Taking simvastatin with Met XL AM 25/5 Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Met XL AM 25/5 Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
AmlodipineEnzalutamide
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using a combination of Met XL AM 25/5 Tablet and enzalutamide may drastically lower Met XL AM 25/5 Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Met XL AM 25/5 Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipinePhenobarbital
Severe
How does the drug interact with Met XL AM 25/5 Tablet:
Using phenobarbital and Met XL AM 25/5 Tablet may drastically lower Met XL AM 25/5 Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of phenobarbital with Met XL AM 25/5 Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-25MGFruit juices, Fruits
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+METOPROLOL SUCCINATE-25MGFruit juices, Fruits
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking Amlodipine and Metoprolol with grapefruit and grapefruit juice significantly increases the metabolism of Amlodipine. Avoid taking Amlodipine and Metoprolol with grapefruit and grapefruit juice.

Diet & Lifestyle Advise

  • Limit the intake of salt in your diet.
  • Cut back on foods that are high in fat and cholesterol.
  • Eat more fruits, vegetables and whole-grain foods.
  • Avoid taking Met XL AM 25/5 Tablet with grapefruit juice as there may be an interaction.
  • Avoid tobacco use. Inform your doctor in case of marijuana use.
  • Dress warmly, as Met XL AM 25/5 Tablet may cause cold extremities.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Met XL AM 25/5 Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are advised not to take alcohol with Met XL AM 25/5 Tablet as there may be an interaction, reducing the therapeutic effects of Met XL AM 25/5 Tablet . Please consult your doctor if you have any concerns.

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Pregnancy

Consult your doctor

Met XL AM 25/5 Tablet may be used in pregnancy only if absolutely warranted. Please consult your doctor if you have any concerns.

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Breast Feeding

Consult your doctor

Met XL AM 25/5 Tablet is not recommended for use during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Caution

Met XL AM 25/5 Tablet may cause dizziness or loss of alertness, which may affect your ability to drive.

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Liver

Consult your doctor

Met XL AM 25/5 Tablet is not recommended for use in those with established liver disease. Please consult your doctor in case of any concerns.

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Kidney

Consult your doctor

Met XL AM 25/5 Tablet is probably safe on the kidney but should be used with caution in those with renal impairment. Please consult your doctor in case of any concerns.

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Children

Unsafe

Met XL AM 25/5 Tablet is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

FAQs

Met XL AM 25/5 Tablet is used to treat high blood pressure/hypertension and‚ angina pectoris.

Met XL AM 25/5 Tablet works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.

Do not stop taking Met XL AM 25/5 Tablet without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking Met XL AM 25/5 Tablet for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Met XL AM 25/5 Tablet .

Hyponatremia (a term for low blood sodium levels) often results in lowering blood pressure and falls. One of the not so common side-effects of Met XL AM 25/5 Tablet is dizziness and lowered BP. Hence, it is best to consult your physician before taking Met XL AM 25/5 Tablet if you suffer from this condition.

Light-headedness could be a side-effect of Met XL AM 25/5 Tablet . It occurs due to low blood pressure, leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better. People taking Met XL AM 25/5 Tablet are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

Met XL AM 25/5 Tablet is not known to affect fertility. However, not enough literature and studies exist to ascertain the effect of Met XL AM 25/5 Tablet on fertility. Please consult your doctor in case of any concerns.

Met XL AM 25/5 Tablet may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

Change your lifestyle in a few essential ways to control your blood pressure. Start by moving; on most days of the week, try to get in at least 30 minutes of exercise, such as swimming or brisk walking. Next, have a well-balanced diet that is rich in fruits, vegetables, lean protein, and whole foods while being low in processed foods, salt, and bad fats. Keep an eye on your weight, drink moderately, and learn stress-reduction techniques like deep breathing or meditation. Aim for 7-8 hours of sleep per night and stay hydrated throughout the day. Try to give up smoking and limit your daily caffeine consumption to one cup of coffee. Don't forget to consult your healthcare practitioner before making any significant adjustments.

Yes. It is effective. Even so, the effectiveness of Met XL AM 25/5 Tablet depends on various factors, such as the individual's medical history, dosage, and response to the medication. It's important to consult with a healthcare professional to determine if this medication is appropriate for your specific condition and to monitor its effectiveness.

Met XL AM 25/5 Tablet is not typically considered a habit-forming medication.

Take Met XL AM 25/5 Tablet as directed. Swallow the tablet whole with water, and take it at the same time each day. Don't crush or chew the tablet. Continue taking the medication even if you feel well, as it helps control your condition. If you need to stop, consult your doctor first to avoid any issues. Regularly check your blood pressure and heart rate, and follow up with your doctor to adjust your dosage as needed.

Met XL AM 25/5 Tablet should be stored in a cool,and dry place away from sunlight. Keep Met XL AM 25/5 Tablet out of the sight and reach of children.

It is not advisable to smoke when taking Met XL AM 25/5 Tablet . Smoking may lessen this medication's effectiveness and heart-healthy improvement effects. In addition to improving your general health, quitting smoking will help your medication function better.

Met XL AM 25/5 Tablet may interact with other medications. Before taking it, consult your doctor to ensure safe use, especially if you're already taking other medications. Never combine it with other medications without your doctor's guidance.

Before taking any medication, including Met XL AM 25/5 Tablet , be sure to tell your doctor if you have any allergies or health conditions or are pregnant or breastfeeding. This will help ensure your safety and avoid any potential interactions or harm.

Met XL AM 25/5 Tablet is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

Country of origin

India

Manufacturer/Marketer address

Ajanta House, Charkop, Kandivli West, Mumbai 400 067, India
Other Info - MET1848

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Author Details

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Oct 21, 2025 | 11:56 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://pubmed.ncbi.nlm.nih.gov/22352120/
  2. https://www.medicines.org.uk/emc/files/pil.5199.pdf
  3. https://www.medicines.org.uk/emc/files/pil.5701.pdf
  4. https://www.researchgate.net/publication/337995043_Method_Development_and_Validation_for_Simultaneous_Estimation_of_Benidipine_Hydrochloride_and_Metoprolol_Succinate_in_Tablet
  5. https://pubmed.ncbi.nlm.nih.gov/21528640/
  6. https://go.drugbank.com/drugs/DB09231
  7. https://www.ohara-ch.co.jp/appendix/pdf/inc03/benidipineHydrochloride8T-SIE.pdf
  8. https://www.webmd.com/drugs/2/drug-8814/metoprolol-succinate-oral/details

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