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compositionComposition:MESALAZINE-1200MG
prescription
Prescription Medicine
info
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Mesabest-OD Tablet is used to treat Ulcerative colitis and Crohn's disease. It contains Mesalazine, an anti-inflammatory drug. It works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. This helps reduce inflammation (redness and swelling) in the intestines and relieves stomach pain or bleeding symptoms. Also, it may prevent further episodes of ulcerative colitis.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MESALAZINE-1200MG

Manufacturer/Marketer :

Abeest International Pvt Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Mesabest-OD Tablet

Mesabest-OD Tablet is a prescription medicine used to treat and manage mild-to-moderate inflammatory bowel conditions, primarily ulcerative colitis. It works directly in the gut to reduce swelling, redness, and tissue damage in the lining of the large intestine. By controlling this irritation, it helps soothe symptoms like abdominal pain and frequent diarrhoea.

For the best results, you should take Mesabest-OD Tablet consistently every day, exactly as prescribed by your healthcare provider, even when you are feeling well. These tablets are typically taken with food, though some specific formulations may vary, so it is important to check your prescription label. Alongside your medication, eating a balanced diet, staying hydrated, and avoiding known food triggers can significantly improve your gut health.

While taking Mesabest-OD Tablet , you may experience mild and temporary side effects like headaches, mild stomach pain, or nausea. However, if you experience more serious issues such as severe abdominal cramps, worsening diarrhoea, fever, or a persistent headache, you should consult your doctor immediately.

Before starting this treatment, tell your doctor if you have a history of kidney problems, liver damage, or asthma. Do not take this if you are allergic to aspirin or any other salicylate medications, as this can trigger a severe allergic reaction.

This medicine can interact with certain other treatments, such as water pills or pain relievers, which can increase the strain on your kidneys. If you are pregnant, breastfeeding, or an older adult, consult your doctor to ensure this treatment is safe and appropriate for your specific needs.

Uses of Mesabest-OD Tablet

Mesabest-OD Tablet is used to treat and manage mild-to-moderate inflammatory bowel conditions. The detailed uses of Mesabest-OD Tablet are as follows:

  • Ulcerative Colitis: It helps reduce swelling, redness, and inflammation in the lining of the large intestine to bring active flare-ups under control.
  • Maintenance of Remission: It is used long-term to keep the disease inactive and prevent symptoms like abdominal pain and diarrhoea from returning.

Key Benefits

Mesabest-OD Tablet helps manage inflammatory bowel disease by reducing inflammation in the intestines. With regular use as prescribed, it helps relieve digestive symptoms, promote healing of the bowel lining, and maintain long-term remission.

  • Reduces Intestinal Inflammation: By acting directly on the inflamed bowel lining, this medicine helps relieve abdominal cramping, urgent bowel movements, rectal bleeding, and other symptoms of intestinal inflammation.
  • Promotes Healing of the Digestive Tract: As inflammation decreases, this medicine supports healing of the intestinal lining, helping restore normal bowel function and improve daily comfort.
  • Helps Maintain Long-Term Remission: Regular use helps keep the condition under control, reducing the frequency of flare-ups and allowing you to enjoy longer periods with few or no symptoms.
Side effects of Mesabest-OD Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
  • Take rest and refrain from doing physical activity for a while, and restart after a few days.
  • Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
  • Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

Directions for Use

  • Mesabest-OD Tablet can be taken 1 hour before or 2 hours after a meal to prevent stomach upset.
  • Follow your doctor's instructions on the dosage and timing of this medication, as it may differ from person to person.
  • Swallow the whole tablet with a glass of water.
  • Do not crush, chew, or break it.

How Mesabest-OD Tablet Works

Mesabest-OD Tablet contains the active ingredient mesalazine, which belongs to a class of anti-inflammatory medicines. Unlike general anti-inflammatory pills that work throughout your whole body, these tablets are specifically designed to travel down to your bowels before releasing the active medicine. Once it reaches the large intestine, the medicine works locally on the gut wall to block the production of certain natural chemicals that cause swelling, irritation, and tissue damage. By stopping these inflammatory chemicals at the source, Mesabest-OD Tablet allows the bowel lining to heal and recover.
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Alcohol

Consult your doctor

It is unknown whether it is safe to consume alcohol with Mesabest-OD Tablet . However, as a precautionary measure, it is advisable not to take or limit alcohol.

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Pregnancy

Consult your doctor

Mesabest-OD Tablet should not be used in pregnancy unless necessary. So, inform your doctor if you are pregnant or suspect pregnancy.

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Breast Feeding

Caution

Mesabest-OD Tablet should not be used in nursing mothers unless necessary. So, inform your doctor if you are a nursing mother.

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Driving

Safe if prescribed

Mesabest-OD Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Please consult your doctor if you have liver problems before using Mesabest-OD Tablet .

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Kidney

Caution

Inform your doctor before taking Mesabest-OD Tablet if you have a history of kidney diseases/conditions. Mesabest-OD Tablet should be used with extreme caution in patients with mild to moderate kidney impairment. It is recommended not to take Mesabest-OD Tablet if you have severe kidney impairment.

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Children

Caution

Mesabest-OD Tablet is not recommended for use in children below 6 yeras of age as the safety and efficacy for this medicine is not established. For children above 6 years, the physician will recommed it if necessary.

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Heart

Caution

Mesabest-OD Tablet can rarely cause heart inflammation, so it's important to be cautious if you already have heart problems. Always consult your doctor before taking it to ensure it's safe for your condition.

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Geriatrics

Caution

Please inform your doctor if you are geriatric before taking Mesabest-OD Tablet , as there is limited information available on its safety in this age group.

What if I have taken an overdose of Mesabest-OD Tablet

If you suspect an overdose or experience severe symptoms like confusion, rapid breathing, or extreme dizziness, seek immediate medical attention or call emergency services right away.

Diet & Lifestyle Advise

  • Keep a food diary: Track what you eat to identify and avoid foods that trigger your symptoms, such as spicy, greasy, or highly processed meals.
  • Eat smaller meals: Consuming smaller, more frequent meals throughout the day can be gentler on your digestive tract than three large meals.
  • Stay well hydrated: Drink plenty of water daily, especially during flare-ups, to replace fluids lost from diarrhoea.
  • Manage stress: Stress can trigger gut inflammation. Practice relaxation techniques like deep breathing, yoga, or light exercise to support your overall gut health.
health query

Have a query?

How Soon It Starts Working

The time required for Mesabest-OD Tablet to start to work: The time required for Mesabest-OD Tablet to show its action is unknown. The time for which the effects of Mesabest-OD Tablet last: The duration of action for Mesabest-OD Tablet is unknown.

What if you forget to take Mesabest-OD Tablet

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular routine. Do not take two doses at the same time to make up for a missed one.

Storage

•Store Mesabest-OD Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check your stools: Some tablets are designed to release medicine slowly. If you consistently notice empty tablet shells in your stool, speak to your doctor.
  • Monitor kidney function: Your doctor will likely order routine blood and urine tests to monitor your kidney and liver health while you are on this medication.
  • Watch for salicylate sensitivity: If you have ever had a bad reaction to aspirin, do not start taking Mesabest-OD Tablet and inform your healthcare provider immediately.
  • Do not stop abruptly: Even if you feel completely healthy, stopping this medication suddenly can cause your bowel inflammation to return.
  • Check the tablet condition: Ensure the tablet is intact before taking it; do not take tablets that are chipped, cracked, or damp.

Drug-Drug Interactions

verifiedApollotooltip
  • Aspirin and NSAIDs (like ibuprofen): Taking these together with Mesabest-OD Tablet may significantly increase the risk of kidney damage.
  • Azathioprine or 6-mercaptopurine: Combining these medications can increase the risk of bone marrow suppression, leading to low blood cell counts.
  • Antacids or Proton Pump Inhibitors (like omeprazole): These can alter stomach acid levels and cause the protective coating on Mesabest-OD Tablet to break down too early in the digestive tract.
MesalazineCidofovir
Critical
MesalazineIodamide
Severe

Drug-Drug Interactions

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MesalazineCidofovir
Critical
How does the drug interact with Mesabest-OD Tablet:
Co-administration of Mesabest-OD Tablet with Cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Mesabest-OD Tablet with Cidofovir is generally avoided as it can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience increased or decreased urination, sudden weight gain or loss, shortness of breath, consult a doctor. Do not discontinue any medications without consulting a doctor.
MesalazineIodamide
Severe
How does the drug interact with Mesabest-OD Tablet:
Co-administration of Iodamide with Mesabest-OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesalamine with Iodamine they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, itchy skin, shortness of breath, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineDeferasirox
Severe
How does the drug interact with Mesabest-OD Tablet:
Co-administration of Deferasirox with Mesabest-OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possibility of interaction between Mesabest-OD Tablet and Deferasirox but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as increased or decreased urination, abrupt weight gain or loss, weakness, or dizziness. Do not discontinue the medication without consulting a doctor.
MesalazineOmeprazole
Severe
How does the drug interact with Mesabest-OD Tablet:
Co-administration of omeprazole with Mesabest-OD Tablet can decrease the effects of Mesabest-OD Tablet.

How to manage the interaction:
There could be a possible interaction between Mesabest-OD Tablet and omeprazole, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineTenofovir alafenamide
Severe
How does the drug interact with Mesabest-OD Tablet:
Co-administration of Tenofovir alafenamide with Mesabest-OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
There is a possibility of interaction between Mesabest-OD Tablet with Tenofovir alafenamide, but they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience increased or decreased urination, swelling, shortness of breath, bone pain, cramping in the muscles. Do not discontinue the medication without consulting a doctor.
MesalazineMetrizamide
Severe
How does the drug interact with Mesabest-OD Tablet:
Co-administration of Metrizamide with Mesabest-OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesabest-OD Tablet with Metrizamide they can be taken together if a doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, dry, itchy skin, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineRanitidine
Severe
How does the drug interact with Mesabest-OD Tablet:
Co-administration of Ranitidine with Mesabest-OD Tablet can decrease the levels of Mesabest-OD Tablet, which may be less effective in treating a condition.

How to manage the interaction:
There may be a possible interaction between Mesabest-OD Tablet with Ranitidine, but they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.
MesalazineIomeprol
Severe
How does the drug interact with Mesabest-OD Tablet:
Co-administration of Iomeprol with Mesabest-OD Tablet may increase the risk of kidney problems.

How to manage the interaction:
Although, there is a possibility of interaction between Mesabest-OD Tablet and Iomeprol they can be taken together if your doctor has prescribed them. Consult a doctor immediately if you experience any symptoms such as swelling in feet and ankles, urinating either too much or too little. Do not discontinue any medication without consulting a doctor.
MesalazineNizatidine
Severe
How does the drug interact with Mesabest-OD Tablet:
Co-administration of Nizatidine with Mesabest-OD Tablet can decrease the level or effect of Mesalamine by increasing gastric pH.

How to manage the interaction:
Although there may be a possible interaction between Mesabest-OD Tablet with Nizatidine, they can be taken together if a doctor has prescribed them. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • No clinically significant food interactions are known with Mesabest-OD Tablet when used as directed. 
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- INFLAMMATORY AGENTS]

FAQs

Mesabest-OD Tablet is used to treat Ulcerative colitis and Crohn's disease.
Mesabest-OD Tablet contains Mesalazine, which works by inhibiting the production of certain chemical substances, such as prostaglandins, that cause pain and swelling. Thereby helps in reducing inflammation (swelling) in the intestines and provides relief from symptoms such as stomach pain or bleeding.
You are not recommended to take Mesabest-OD Tablet with Ibuprofen as co-administration of these two medicines may increase the risk of kidney problems. However, please consult your doctor before taking Mesabest-OD Tablet with other medicines.
Mesabest-OD Tablet should be used with caution in patients with stomach ulcers as it may increase the risk of worsening the condition. Therefore, please inform your doctor if you have a stomach ulcer before taking Mesabest-OD Tablet .
Yes, Mesabest-OD Tablet may cause diarrhoea as a common side effect. However, if the condition persists and worsens with fever, watery stools or consistent stomach pain, please consult a doctor. Also, drink plenty of water while taking Mesabest-OD Tablet to prevent dehydration.
No, you must swallow the tablets whole. Crushing or chewing them destroys the special protective coating designed to ensure the medicine reaches your large intestine before dissolving. Talk to your doctor if you have trouble swallowing tablets.
No, you should not take this medication if you have a known allergy to aspirin or other salicylates. Doing so can cause a severe allergic reaction. Talk to your doctor to find an alternative treatment.
While there is no direct interaction between alcohol and this medicine, alcohol can irritate your digestive tract and worsen symptoms of bowel inflammation. It is best to limit or avoid alcohol. Talk to your doctor for personalised advice.
Yes, many women continue taking this medicine during pregnancy to keep their bowel disease in remission, but it must be done under close medical supervision. Talk to your doctor to weigh the benefits and potential risks.
Some extended-release tablets may pass through your body looking intact after the active medicine has been absorbed. However, if this happens regularly, talk to your doctor or pharmacist to ensure you are receiving the proper dose.
Weight gain is not a common side effect of this medication. However, as your gut heals and your appetite improves, you may experience some natural weight recovery. Talk to your doctor if you have concerns about weight changes.
Yes. Mesabest-OD Tablet can rarely affect kidney function and may also be associated with kidney stones in some patients. Your doctor may recommend regular kidney-function tests during treatment. Drink adequate fluids unless your doctor has advised otherwise. Contact your doctor if you develop changes in urination, blood in the urine, severe side pain, or other symptoms of kidney problems.

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Country of origin

India
Other Info - MES0132

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