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  3. Mepraz Tablet 10's

Mepraz Tablet 10's, Pack of 10 TABLETS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Mepraz Tablet is used to treat several conditions such as duodenal ulcers (sores in the upper part of the small intestine), gastro-oesophageal reflux disease or GERD (when acid from the stomach flows back into the food pipe), heartburn (a burning feeling in the chest caused by acid), erosive oesophagitis (damage to the food pipe lining from stomach acid), infections caused by Helicobacter pylori (a type of bacteria that affects the stomach, usually treated with antibiotics), and Zollinger-Ellison syndrome (a rare condition where the stomach makes too much acid). It contains Rabeprazole, which helps reduce the amount of acid your stomach produces. This allows ulcers and other acid-related conditions to heal and helps prevent them from recurring. Common side effects may include headache, dizziness, nausea, vomiting, constipation or diarrhoea, gas, fatigue, or a runny nose. Before using this medicine, inform your doctor if you are allergic to any of its ingredients, are pregnant or breastfeeding, or if you are taking other medication or have any existing health problems.

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Synonym :

RABEPRAZOLE SODIUM

Composition :

RABEPRAZOLE-20MG

Manufacturer/Marketer :

Globus Remedies Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Mepraz Tablet

Mepraz Tablet belongs to a group of medicines called proton pump inhibitors, which are used to reduce the amount of acid produced in the stomach. It is commonly prescribed to treat duodenal ulcers (sores in the upper part of the small intestine), gastro-oesophageal reflux disease or GERD (when stomach acid flows back into the food pipe), heartburn (a burning feeling in the chest caused by acid), and erosive oesophagitis (damage to the lining of the food pipe due to acid). It is also used to treat infections caused by a stomach bacteria called Helicobacter pylori (along with antibiotics), and a rare condition called Zollinger-Ellison syndrome (when the stomach makes too much acid).

Mepraz Tablet contains Rabeprazole, which works by blocking the acid-producing pumps in the stomach. By reducing acid levels, it helps relieve symptoms, allows ulcers and damaged areas to heal, and prevents new ulcers from forming.

Your doctor will decide the correct dose and duration depending on your condition, so it’s essential to follow their instructions carefully. Some people may experience side effects while taking Mepraz Tablet . Common ones include headache, dizziness, diarrhoea, constipation, nausea, vomiting, gas (bloating), weakness, or a runny nose. These are usually mild and go away on their own. However, if any of these symptoms continue or become bothersome, you should contact your doctor.

Before taking Mepraz Tablet , inform your doctor if you have any liver problems or a stomach tumour. Long-term use may lower magnesium and vitamin B12 levels, and slightly increase the risk of bone fractures. Avoid alcohol, as it can increase stomach acid and side effects like drowsiness. Additionally, this medication may cause drowsiness or dizziness, so avoid driving or operating machinery until you feel fully alert. Mepraz Tablet is not recommended for children, and if you are pregnant or breastfeeding, consult your doctor before using it.

Uses of Mepraz Tablet

Mepraz Tablet is used to treat the following conditions:

  • Gastro-oesophageal Reflux Disease (GERD): Relieves heartburn and acid reflux by reducing stomach acid.
  • Erosive Oesophagitis: Heals damage to the food pipe caused by excess stomach acid.
  • Duodenal Ulcers: Helps heal sores in the upper part of the small intestine.
  • Gastric Ulcers: Treats and heals ulcers in the stomach lining.
  • Helicobacter pylori Infection (with antibiotics): Helps eliminate bacteria that cause ulcers.
  • Zollinger-Ellison Syndrome: Controls excessive acid production in the stomach.

Directions for Use

  • Mepraz Tablet can be taken with or without food depending on the medical condition. However, it is preferable to take it at least 30 minutes before a meal for better efficacy.
  • It is usually taken 1-2 times daily or as prescribed by your doctor.
  • Swallow Mepraz Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.

Medicinal Benefits

  • Mepraz Tablet contains Rabeprazole, a proton pump inhibitor (PPI) used to treat conditions caused by excess stomach acid.
  • It is commonly prescribed to manage acid-related disorders such as gastric and duodenal ulcers, acid reflux, and GERD (gastro-oesophageal reflux disease).
  • Rabeprazole works by blocking proton pumps in the stomach lining, which are responsible for producing acid.
  • By reducing acid levels, Mepraz Tablet helps relieve symptoms like heartburn, indigestion, and sour burps.
  • It also promotes the healing of ulcers and acid-related damage in the oesophagus (food pipe).
  • When taken as prescribed, Mepraz Tablet helps prevent the recurrence of ulcers and effectively manages chronic conditions such as GERD and Zollinger-Ellison syndrome.
  • Maintaining a healthy diet, avoiding spicy or acidic foods, reducing stress, quitting smoking, and limiting alcohol can improve the effectiveness of Mepraz Tablet and support better digestive health over time.

How Mepraz Tablet Works

Mepraz Tablet contains 'Rabeprazole' that works by blocking the action of the enzyme known as gastric proton pump which is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Mepraz Tablet
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

What if I have taken an overdose of Mepraz Tablet

Do not take more than the prescribed dose. Using more medication will not improve your symptoms; rather, they may cause poisoning or serious side effects. If you suspect that you may have overdosed of Mepraz Tablet or if you experience any adverse events, please go to the emergency department of the closest hospital.

Drug Warnings

  • Do not take Mepraz Tablet if you are allergic to Rabeprazole or any of its ingredients.
  • Inform your doctor if you have liver problems, gastrointestinal conditions, or are scheduled for specific lab tests (e.g., Chromogranin A), as Rabeprazole may affect results.
  • Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding, before starting Mepraz Tablet .
  • Seek medical attention if you experience symptoms such as severe abdominal pain, persistent diarrhoea, dizziness, muscle cramps, or signs of low magnesium or vitamin B12 deficiency.
  • Let your doctor know about all other medications you are taking, including over-the-counter drugs, herbal products, or supplements, to avoid interactions.
  • Use in children is not recommended, as the safety and effectiveness of Mepraz Tablet have not been established in pediatric patients.
  • Elderly patients (65 years and above) should use Mepraz Tablet with caution, as they may be at greater risk for side effects like low magnesium levels, vitamin B12 deficiency, and bone fractures with long-term use.

Drug-Drug Interactions

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OmeprazoleErlotinib
Critical
OmeprazoleRilpivirine
Critical

Drug-Drug Interactions

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OmeprazoleErlotinib
Critical
How does the drug interact with Mepraz Tablet:
Mepraz Tablet can make Erlotinib less effective by reducing its absorption in the body. This can lead to low treatment outcomes.

How to manage the interaction:
Taking Mepraz Tablet and Erlotinib together is not recommended as it can result in an interaction; it should be taken only if a doctor has advised it. Do not stop using any medications without talking to a doctor.
OmeprazoleRilpivirine
Critical
How does the drug interact with Mepraz Tablet:
Using rilpivirine together with Mepraz Tablet can decrease the absorption and blood levels of rilpivirine.

How to manage the interaction:
Taking Mepraz Tablet with Rilpivirine can cause an interaction, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
OmeprazoleClopidogrel
Severe
How does the drug interact with Mepraz Tablet:
When taken together Mepraz Tablet can lower the levels of Clopidogrel in the blood, which can result in a decreased effectiveness of clopidogrel.

How to manage the interaction:
Taking Mepraz Tablet and clopidogrel together has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
OmeprazoleGefitinib
Severe
How does the drug interact with Mepraz Tablet:
When taken together Mepraz Tablet may interfere with the absorption of gefitinib into the bloodstream and reduce its effectiveness.

How to manage the interaction:
Although taking Mepraz Tablet with gefitinib can lead to interaction, they can be taken if recommended by a doctor. However, if you have no other treatment options, it is suggested that you take gefitinib 12 hours before or after Mepraz Tablet to reduce the impact of the interaction. Do not stop using any medications without talking to a doctor.
OmeprazoleCarbamazepine
Severe
How does the drug interact with Mepraz Tablet:
Taking Mepraz Tablet and carbamazepine may possibly reduce the effects of Mepraz Tablet, which could reduce its capacity to treat the condition.

How to manage the interaction:
Although taking Mepraz Tablet and carbamazepine together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without consulting a doctor.
OmeprazoleTacrolimus
Severe
How does the drug interact with Mepraz Tablet:
Taking tacrolimus with Mepraz Tablet may significantly increase the blood levels of tacrolimus, which may increase the risk of serious side effects (high sugars, infections, kidney problems, hyperkalemia - high blood levels of potassium).

How to manage the interaction:
Although taking Mepraz Tablet with tacrolimus can lead to interaction, they can be taken if recommended by a doctor. However, consult the doctor if you experience irregular heart rhythm, palpitations (fast heartbeat), muscle spasm, tremor (shaking of hands & legs), and seizures(fits). Do not stop using any medications without talking to a doctor.
OmeprazoleNelfinavir
Severe
How does the drug interact with Mepraz Tablet:
Using Mepraz Tablet in conjunction with nelfinavir can reduce the effectiveness of nelfinavir.

How to manage the interaction:
Although taking Mepraz Tablet with nelfinavir can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleIsoniazid
Severe
How does the drug interact with Mepraz Tablet:
When Mepraz Tablet is taken with Isoniazid, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Mepraz Tablet with Isoniazid can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without talking to a doctor.
OmeprazolePazopanib
Severe
How does the drug interact with Mepraz Tablet:
Mepraz Tablet may interfere with pazopanib absorption and reduces its effectiveness.

How to manage the interaction:
Although taking Mepraz Tablet with pazopanib can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.
OmeprazoleAcalabrutinib
Severe
How does the drug interact with Mepraz Tablet:
Mepraz Tablet, through decreasing stomach acidity, may interfere with the absorption of acalabrutinib capsules and reduce their effectiveness.

How to manage the interaction:
Although taking Mepraz Tablet with acalabrutinib can lead to interaction, they can be taken if recommended by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat smaller meals more often.
  • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
  • Maintain a healthy weight by regular exercising.
  • Avoid lying down after eating to prevent acid reflux.
  • Avoid tight-fitting clothes as it might increase the pressure on the abdomen, leading to acid reflux.
  • Practise relaxation techniques and avoid stress by doing yoga or meditation.
  • Avoid foods such as high-fat, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
  • Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by brisk walking or stretching.

Habit Forming

No

Therapeutic Class

ANTIULCERS

Mepraz Tablet Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Unsafe

Avoid consumption of alcohol while taking Mepraz Tablet . Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

bannner image

Pregnancy

Caution

Please consult your doctor if you are pregnant. Your doctor will weigh the benefits and any potential risks before prescribing Mepraz Tablet .

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Breast Feeding

Caution

Please consult your doctor if you are breastfeeding. Your doctor will decide if Mepraz Tablet can be taken by breastfeeding mothers or not.

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Driving

Caution

Mepraz Tablet may cause dizziness and sleepiness. Do not drive or operate machinery unless you are alert.

bannner image

Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

bannner image

Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Unsafe

Mepraz Tablet is not recommended for children as the safety and effectiveness were not established.

Have a query?

FAQs

Mepraz Tablet is used to treat duodenal ulcers, gastro-oesophageal reflux disease (reflux of gastric contents into the oesophagus), heartburn, erosive oesophagitis (acid-related damage to the lining of the oesophagus), infections caused by Helicobacter pylori when given along with an antibiotic, and Zollinger-Ellison syndrome.

Mepraz Tablet works by blocking the action of the enzyme known as gastric proton pump that is responsible for the production of acid. This helps in reducing the amount of acid produced, heals the ulcers and prevents the formation of new ulcers.

Talk to your doctor if you do not feel better even after taking Mepraz Tablet for 14 days. Do not take Mepraz Tablet for longer durations unless prescribed by the doctor. If Mepraz Tablet is prescribed for longer durations, a regular check-up is advised.

Do not discontinue Mepraz Tablet without consulting your doctor. To treat your condition effectually, continue taking Mepraz Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Mepraz Tablet .

Diarrhoea might be a side-effect of Mepraz Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Prolonged intake of Mepraz Tablet is linked with a greater risk of Clostridium difficile-associated diarrhoea, so if you develop diarrhoea that does not improve, immediately consult a doctor.

Dry mouth could be a side effect of Mepraz Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might help stimulate saliva and thereby prevent dry mouth.

On long-term treatment, Mepraz Tablet might increase the risk of fractures of the hip, spine, and wrist. Inform your doctor if you have osteoporosis or if you are taking corticosteroids.

Mepraz Tablet should be used with caution in the elderly as it may cause bone weakness and increased risk of fractures if taken for longer duration.

Inform your doctor before taking Mepraz Tablet if you are due to have Chromogranin A blood test. Mepraz Tablet may cause abnormal blood and liver enzyme values. Inform the person doing the tests that you are taking Mepraz Tablet . This medicine may cause dizziness and sleepiness, so drive only if you are alert.

Long term treatment with Mepraz Tablet may cause malabsorption of vitamin B12 leading to its deficiency. Consult the doctor if you notice symptoms of cyanocobalamin deficiency like tiredness, sore mouth, mouth ulcers and pins & needles sensation.

Mepraz Tablet can be taken on an empty stomach as it helps regulate acid production.

Side effects of Mepraz Tablet include headache, dizziness, diarrhoea, constipation, nausea, vomiting, flatulence (wind), weakness, and runny nose. Consult the doctor if the side effects persist or worsen.

Country of origin

India

Manufacturer/Marketer address

14/11/2 Site No.4, Sahibabad Industrial Area Site 4, Ghaziabad, Uttar Pradesh 201010
Other Info - MEP0057

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Bayyarapu Mahesh KumarDoctor badge

Reviewed By

Bayyarapu Mahesh Kumar

M Pharmacy

Last Updated

Aug 8, 2025 | 11:56 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.2842.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020973s035204736s005lbl.pdf
  3. https://www.nhs.uk/medicines/rabeprazole/
  4. https://www.drugs.com/mtm/rabeprazole.html

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