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compositionComposition:MAGNESIUM SULFATE-50%W/V
prescription
Prescription Medicine
info
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Megfill Injection 2 ml is used to treat, prevent, and control seizures (fits) in preeclampsia and eclampsia (severe complications in pregnancy that occur due to high blood pressure). It contains Magnesium sulfate. It is a mineral supplement and an electrolyte. It is also an anticonvulsant that prevents and controls seizures (fits) in preeclampsia and eclampsia. It is also used to treat abnormally low magnesium levels in the blood. It works by blocking neuromuscular transmission. It further has a depressant effect on the central nervous system. Magnesium sulfate aids in the normal functioning of cells, nerves, muscles, bones, and the heart.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

MAGNESIUM SULFATE-50%W/V

Manufacturer/Marketer :

GLEE BIOTECH LIMITED

Consume Type :

Parenteral

Expires on or after :

Nov-27

Return Policy :

Not Returnable

About Megfill Injection 2 ml

Megfill Injection 2 ml is a prescription injection used to treat and prevent critically low levels of an essential mineral in the body. It is also commonly used to prevent and control life-threatening seizures in pregnant women with severe pre-eclampsia or eclampsia. Additionally, healthcare providers use this sterile solution to manage certain serious heart rhythm emergencies and protect the brains of premature babies.

Because Megfill Injection 2 ml is given as an injection or intravenous infusion, it is typically administered in a hospital or clinic setting under close clinical supervision. The frequency and duration of your treatment depend entirely on your specific medical condition and how your body responds to the medicine. Eating a balanced diet rich in leafy greens, nuts, and whole grains can help support healthy mineral levels once your immediate medical emergency is resolved.

While receiving this injection, you may experience temporary side effects such as flushing, sweating, or a warm feeling. However, you must inform your healthcare provider immediately if you experience serious symptoms like extreme muscle weakness, a very slow heart rate, or difficulty breathing. Your medical team will monitor you closely during the injection to catch and treat any severe reactions right away.

Before receiving Megfill Injection 2 ml, tell your doctor if you have kidney disease, heart problems, or a muscle disorder like myasthenia gravis. Do not take this if you have severe heart block or severe kidney failure, as your body may not be able to clear the medicine safely. Your doctor will carefully weigh the risks and benefits before starting this treatment.

Megfill Injection 2 ml can interact with certain medications, including blood pressure drugs and muscle relaxants, which may excessively weaken your muscles or lower your blood pressure. Pregnant women, breastfeeding mothers, and elderly patients require careful clinical monitoring, as dosing needs to be highly customised to ensure safety. Talk to your doctor or pharmacist if you are pregnant, breastfeeding, or have pre-existing kidney conditions before receiving this medicine.

Uses of Megfill Injection 2 ml

Megfill Injection 2 ml is used to treat seizures (fits) in preeclampsia, eclampsia, and low magnesium levels. The detailed uses of Megfill Injection 2 ml are as follows:

  • Seizure prevention in pre-eclampsia and eclampsia: Megfill Injection 2 ml acts on the central nervous system to prevent and control dangerous seizures in pregnant women with dangerously high blood pressure.
  • Severe mineral deficiency: Megfill Injection 2 ml quickly restores essential mineral levels when oral supplements are not fast enough or cannot be tolerated.
  • Irregular heart rhythm (Torsades de Pointes): Megfill Injection 2 ml helps stabilise the electrical activity of the heart in this specific, life-threatening heart rhythm emergency.
  • Brain protection in preterm infants: Megfill Injection 2 ml is given to mothers in premature labour to help reduce the risk of cerebral palsy and other neurological issues in the baby.

Key Benefits

Megfill Injection 2 ml prevents and controls seizures (fits) in preeclampsia and eclampsia. It also treats low magnesium levels.
Benefits may include:

  • Megfill Injection 2 ml provides rapid, lifesaving protection during pregnancy complications by preventing severe seizures.
  • By quickly correcting severe mineral imbalances, this injection restores normal muscle and nerve function, helping to relieve symptoms like severe muscle cramps, spasms, and weakness.
  • In critical care settings, Megfill Injection 2 ml also helps stabilise certain dangerous heart rhythm problems, improving the heart's electrical activity and reducing the risk of serious complications.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Megfill Injection 2 ml will be administered by a healthcare professional.
  • Do not self-administer.

How Megfill Injection 2 ml Works

Megfill Injection 2 ml replaces magnesium, an essential mineral that helps your nerves, muscles, heart, and blood vessels work properly. Think of magnesium as helping keep your body's electrical signals balanced. When magnesium levels are too low, or certain medical emergencies occur, these signals can become overactive. By restoring magnesium levels, this medicine helps calm these electrical signals. This helps prevent seizures, relaxes blood vessels and muscles, supports a normal heartbeat, and reduces abnormal muscle contractions.
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Alcohol

Caution

Avoid taking alcohol while using Megfill Injection 2 ml since it may interact and worsen the side effects. Please seek medical advice for more information.

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Pregnancy

Caution

Megfill Injection 2 ml is a pregnancy category D drug and has shown harmful effects on the foetus. However, seizure control is mandatory during eclampsia in pregnancy. Inform your doctor if you are pregnant or planning pregnancy. Your doctor will prescribe Megfill Injection 2 ml if the benefits outweigh the risks.

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Breast Feeding

Caution

Magnesium sulfate passes into breast milk. If you are breastfeeding, please inform your doctor before receiving Megfill Injection 2 ml.

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Driving

Caution

You may experience dizziness and drowsiness while using Megfill Injection 2 ml. In such cases, do not drive or operate machinery until you are mentally alert and focused.

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Liver

Caution

Megfill Injection 2 ml should be used with caution in patients with liver problems. Please inform your doctor if you have a liver impairment. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Megfill Injection 2 ml should be used with caution in patients with kidney problems. Please inform your doctor if you have kidney impairment. Your doctor may adjust your dose depending on your current medical conditions.

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Children

Unsafe

Megfill Injection 2 ml is not recommended in children below 12 years of age.

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Heart

Caution

Megfill Injection 2 ml should be avoided in heart patients unless specifically prescribed by a doctor. It can affect blood pressure and heart rhythm, requiring careful evaluation before use.

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Geriatrics

Caution

Geriatric patients should avoid Megfill Injection 2 ml unless specifically prescribed by a doctor. Older adults may be more sensitive to its effects on heart rhythm and blood pressure, requiring close evaluation before use.

What if I have taken an overdose of Megfill Injection 2 ml

An overdose of Megfill Injection 2 ml is a medical emergency. Symptoms may include extreme muscle weakness, severe drowsiness, difficulty breathing, a very slow heartbeat, or a dangerous drop in blood pressure. Call emergency medical service or go to the nearest emergency room immediately if an overdose is suspected.

Diet & Lifestyle Advise

  • Monitor your fluid intake: Since your kidneys process Megfill Injection 2 ml, drink plenty of water as advised by your doctor to help your body flush the medicine properly, unless you are on a restricted fluid schedule.
  • Eat mineral-rich foods: Support your recovery by incorporating mineral-rich foods into your daily meals, such as spinach, pumpkin seeds, almonds, and avocados, once your doctor confirms it is safe.
  • Limit salt intake: If you are receiving this medicine for pregnancy-related high blood pressure, reduce your sodium intake to help manage your blood pressure naturally.
  • Avoid alcohol and smoking: These habits can deplete your body's essential minerals and worsen heart or blood pressure conditions, making your treatment less effective.
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How Soon It Starts Working

The time required for Megfill Injection 2 ml to start to work: Megfill Injection 2 ml can show its effect in 1 hour of IM administration and immediatoey after IV administration. The time for which the effects of Megfill Injection 2 ml last: Megfill Injection 2 ml effect asts for 3 to 4 hours after IM administration, and 30 minutes after IV administration.

What if you forget to take Megfill Injection 2 ml

Since Megfill Injection 2 ml is usually given in a hospital setting by a healthcare professional, a missed dose is highly unlikely. If you are receiving this treatment at home and miss a scheduled dose, contact your doctor or healthcare provider immediately for instructions. Do not double the dose to catch up.

Storage

• Store Megfill Injection 2 ml at controlled room temperature, ideally between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Check the solution: Always inspect the liquid in the vial before injecting. If you notice any cloudiness, particles, or a change in colour, do not use it and contact your pharmacist.
  • Rotate injection sites: If you are receiving intramuscular injections, rotate the injection site each time to minimise muscle pain, bruising, and tissue damage.
  • Monitor kidney health: Have regular blood tests as ordered by your doctor to ensure your kidneys are functioning well enough to clear this medicine safely.
  • Avoid driving: Do not drive, operate machinery, or perform tasks that require alertness immediately after receiving Megfill Injection 2 ml, as it can cause temporary dizzines or muscle weakness.
  • Use safe needle practices: Never reuse needles or syringes, and always use a designated sharps container to prevent accidental needle stick injuries.

verifiedApollotooltip
  • Calcium channel blockers (e.g., nifedipine): May cause a dangerous drop in blood pressure and severe muscle weakness.
  • Neuromuscular blockers (muscle-relaxing medicines used during surgery): Megfill Injection 2 ml can increase the effects of these medicines, leading to prolonged muscle weakness and breathing problems.
  • Central nervous system depressants (such as sleeping medicines or strong opioid pain medicines): Using these together can increase drowsiness and slow breathing.

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verifiedApollotooltip
  • No clinically significant food interactions are known with Megfill Injection 2 ml when used as directed.

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[MINERALS, ANTICONVULSANT]

FAQs

Megfill Injection 2 ml is used to treat Seizures (fits) in preeclampsia, eclampsia, and hypomagnesaemia.
Megfill Injection 2 ml contains Magnesium sulfate. It works by treating low levels of magnesium in the body in hypomagnesaemia. It also prevents and controls seizures that occur due to high blood pressure in pregnancy. It works by blocking the nerve impulses to the heart muscles.
If you drink alcohol or caffeine drinks, smoke, or use any street drugs regularly, please inform your doctor before starting Megfill Injection 2 ml. These products may affect the working of Megfill Injection 2 ml.
Inform your doctor if you have kidney/liver/heart diseases, dehydration, stomach/gastrointestinal disorders, and myasthenia gravis (muscle weakness) before using Megfill Injection 2 ml. Magnesium sulfate is not recommended for use in severely impaired renal function. It should not be used in a hepatic coma if there is a risk of renal failure.
Megfill Injection 2 ml contains magnesium sulphate, which prevents and treats low magnesium levels in your body (hypomagnesaemia).
Yes. Megfill Injection 2 ml is commonly used during pregnancy to prevent seizures in women with severe pre-eclampsia or eclampsia and may also be given before very preterm birth to help protect the baby's brain. It is always administered under close medical supervision.
It is given either through a vein (IV infusion) or as an injection into a muscle by a trained healthcare professional. Most patients receive it in a hospital where their breathing, reflexes, and other vital signs can be monitored.
Mild tiredness can occur, but increasing muscle weakness, difficulty speaking, or trouble breathing may indicate that magnesium levels are too high. Inform your healthcare provider immediately.
Wait until you feel fully alert and your healthcare provider confirms it is safe. This medicine may temporarily cause dizziness, drowsiness, or muscle weakness.
Possibly, but people with kidney disease usually need lower doses and closer monitoring because magnesium can build up in the body when the kidneys are not working normally.
Early signs include unusual drowsiness, reduced reflexes, muscle weakness, slurred speech, slow breathing, or a slow heartbeat. Healthcare professionals monitor for these signs throughout treatment.
Yes. Some blood pressure medicines, especially calcium channel blockers such as nifedipine, can increase the risk of low blood pressure or muscle weakness when used with Megfill Injection 2 ml. Your healthcare provider will monitor you if these medicines need to be used together.
Most people receive Megfill Injection 2 ml in a hospital or clinic. Home administration is uncommon and should only be done when specifically recommended and after formal training by a qualified healthcare professional.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

315, 3rd Floor, SAS Towers, Medicity, Sector 38, Gurgaon, Haryana
Other Info - MEG0782

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