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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

Megazolid 600 Tablet is an antibiotic medication used to treat bacterial infections of the skin and lungs (pneumonia). It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections. It contains Linezolid, which works by stopping the growth of infection-causing bacteria. Thus, it helps treat the bacterial infection. In some cases, you may experience common side effects, such as thrush (a fungal infection), headache, a metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Before taking this medicine, inform your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and any pre-existing medical conditions.

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Composition :

LINEZOLID-600MG

Manufacturer/Marketer :

Aristo Pharmaceuticals Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Megazolid 600 Tablet

Megazolid 600 Tablet is used to treat bacterial infections of the skin and lungs (pneumonia). It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections. Bacterial infections are caused by the multiplication of harmful bacteria inside or on the body. Megazolid 600 Tablet does not work against infections caused by the virus, including cold and flu.

Megazolid 600 Tablet contains Linezolid, which works by inhibiting the bacteria's ability to produce proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.

In some cases, you may experience common side effects, such as thrush (a fungal infection), headache, a metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Do not take Megazolid 600 Tablet on your own, as self-medication may lead to antibiotic resistance, in which antibiotics fail to act against specific bacterial infections. Consult your doctor if you are pregnant or planning to become pregnant before taking Megazolid 600 Tablet . Megazolid 600 Tablet passes into breastmilk, so do not take Megazolid 600 Tablet if you are breastfeeding. Megazolid 600 Tablet may cause dizziness and vision problems; therefore, exercise caution when driving and operating machinery. Avoid alcohol consumption while taking Megazolid 600 Tablet , as it may cause increased dizziness.

Uses of Megazolid 600 Tablet

Megazolid 600 Tablet is used in the treatment of bacterial infections caused by Gram-positive bacteria. The detailed uses of Megazolid 600 Tablet are as follows:<br/> • Pneumonia (Lung Infection): Megazolid 600 Tablet is effective in treating both community-acquired and hospital-acquired pneumonia caused by susceptible bacteria.<br/> • Skin and Skin Structure Infections: Megazolid 600 Tablet is used to treat mild to severe bacterial infections of the skin and its underlying tissues. It is also indicated for the treatment of diabetic foot infections, without associated bone infections (osteomyelitis).<br/> • Antibiotic-Resistant Infections: Megazolid 600 Tablet is indicated for infections caused by the bacteria Enterococcus faecium that are resistant to vancomycin, including intra-abdominal infections, skin and soft tissue infections, urinary tract infections, and concurrent bacteremia (presence of bacteria in the bloodstream).<br/>

Directions for Use

  • Megazolid 600 Tablet can be taken with or without food, as advised by your doctor.
  • Your doctor will decide the appropriate dosage and timing based on your medical condition.
  • Swallow Megazolid 600 Tablet as a whole with a glass of water.
  • Do not crush or chew this medication.

Medicinal Benefits

Megazolid 600 Tablet belongs to the class of antibiotics called oxazolidinones, used to treat bacterial infections of the skin and lungs (pneumonia). It is also effective in treating vancomycin-resistant enterococcal infections, diabetic foot infections, intra-abdominal infections, urinary tract infections, and concurrent bacteremia (presence of bacteria in the bloodstream). Megazolid 600 Tablet contains Linezolid, which works by stopping the growth of infection-causing bacteria. Thus, it helps treat the bacterial infection.

How Megazolid 600 Tablet Works

Megazolid 600 Tablet contains Linezolid (an antibiotic), which works by stopping the bacteria from making proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Megazolid 600 Tablet
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
  • Eat fiber-rich foods like broccoli, cauliflower, leafy greens, and Brussels sprouts.
  • Limit sugar and refined carbs like avoid sugary drinks, white bread, and processed foods.
  • Choose lean protein sources like chicken, fish, and tofu.
  • Choose low-sugar fruits like berries, citrus fruits, and apples in moderation.
  • Maintain good hygiene and keep affected areas clean and dry.
  • Wear breathable clothing to reduce moisture.
  • Consider natural antifungal agents like coconut oil, tea tree oil, and garlic (consult a healthcare professional before use).

What if I have taken an overdose of Megazolid 600 Tablet

Do not take more than the prescribed dose of Megazolid 600 Tablet , as it may cause an overdose. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

Do not take Megazolid 600 Tablet if you are allergic to any of its contents; if you are taking or have taken monoamine oxidase (MAO) inhibitors in the last 14 days. Talk to your doctor if you have high blood pressure, an overactive thyroid, phaeochromocytoma (tumour of adrenal glands), carcinoid syndrome (tumours of the hormone system), manic depression, schizophrenia, confusion, or other mental problems. Inform your doctor if you bruise or bleed easily, have anaemia (low red blood cells), are prone to infections, have a history of seizures, are on dialysis, have diarrhoea, or kidney or liver problems. Consult your doctor immediately if you experience a throbbing headache after eating or drinking, vision problems, loss of sensation or tingling and prickling sensations in your arms and legs, persistent diarrhoea, nausea, vomiting, abdominal pain, or rapid breathing. Consult your doctor if you are pregnant before taking Megazolid 600 Tablet . Megazolid 600 Tablet passes into breastmilk, so do not take Megazolid 600 Tablet if you are breastfeeding. Megazolid 600 Tablet may cause dizziness and vision problems; therefore, exercise caution when driving and operating machinery. Avoid alcohol consumption while taking Megazolid 600 Tablet , as it may cause increased dizziness.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Megazolid 600 Tablet:
Taking Megazolid 600 Tablet with Fluvoxamine can increase the risk of serotonin syndrome( a condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Megazolid 600 Tablet with Fluvoxamine is not recommended but can be taken together if prescribed by a doctor. However, if you experience confusion, hallucination (seeing & hearing things that do not exist), seizure(fits), extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor (shaking of hands & legs), incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Megazolid 600 Tablet:
When Megazolid 600 Tablet is taken with Sertraline, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
taking Megazolid 600 Tablet and Sertraline is not recommended, but it can be taken if prescribed by a doctor. If you notice any of these signs - like confusion, hallucination, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramps, nausea, vomiting, and diarrhoea-contact a doctor right away. Do not stop using any medications without a doctor's advice.
LinezolidCaffeine
Critical
How does the drug interact with Megazolid 600 Tablet:
Taking these two together can cause your blood pressure to rise, a condition known as a hypertensive crisis.

How to manage the interaction:
Taking Caffeine with Megazolid 600 Tablet is not recommended, please consult your doctor before taking it. It can be taken if your doctor prescribes it. Do not stop taking any medication without consulting your doctor.
How does the drug interact with Megazolid 600 Tablet:
Using Tapentadol together with Megazolid 600 Tablet might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Tapentadol with Megazolid 600 Tablet is not recommended, consult a doctor before taking it. If you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, blurred vision, muscle spasm or stiffness, tremors, stomach cramps, nausea, vomiting, and diarrhea call a doctor right away. Do not stop using any medications without talking to a doctor.
How does the drug interact with Megazolid 600 Tablet:
Using Megazolid 600 Tablet together with mirtazapine might raise serotonin hormone levels in the body, affecting the brain and nerve cells. Increased serotonin hormone can lead to severe side effects.

How to manage the interaction:
Taking Megazolid 600 Tablet with Mirtazapine can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Megazolid 600 Tablet:
Co-administration of Megazolid 600 Tablet with Vortioxetine can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Megazolid 600 Tablet with Vortioxetine can result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea consult a doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Megazolid 600 Tablet:
Coadministration of Megazolid 600 Tablet with Modafinil can increase the levels of Modafinil and increase the risk or severity of high blood pressure.

How to manage the interaction:
Taking Modafinil with Megazolid 600 Tablet can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, excessive sweating, shortness of breath, chest pain or tightness, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Megazolid 600 Tablet:
Taking Rasagiline with Megazolid 600 Tablet can increase the risk of serotonin syndrome (A condition in which a chemical called serotonin increase in your body).

How to manage the interaction:
Taking Megazolid 600 Tablet with Rasagiline is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm, stomach cramp, nausea, vomiting, and diarrhea contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Megazolid 600 Tablet:
When Vilazodone is taken with Megazolid 600 Tablet, may increase the risk of serotonin syndrome (a condition in which a chemical called serotonin increases in your body).

How to manage the interaction:
Taking Vilazodone with Megazolid 600 Tablet together can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you experience any symptoms such as severe confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasms or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Megazolid 600 Tablet:
Taking Megazolid 600 Tablet with Epinephrine can increase the risk of high blood pressure.

How to manage the interaction:
Taking Megazolid 600 Tablet with Epinephrine is not recommended as it can result in an interaction. It should be taken only if a doctor has advised it. However, if you experience confusion, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics, such as yogurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto, and cheese.
  • Eat fibre-rich food like whole grains, lentils, berries, broccoli, peas, and bananas.
  • Avoid foods rich in calcium, grapefruit, and grapefruit juice, as they might hinder the absorption of antibiotics.
  • Avoid consuming tyramine-rich food or drinks, such as meat, cheese, fish, red wine, beer, certain beans, and fermented yeast products.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS
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Alcohol

Unsafe

Avoid consuming alcohol while taking Megazolid 600 Tablet , as it may cause increased dizziness.

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Pregnancy

Caution

Megazolid 600 Tablet belongs to pregnancy category C. If you are pregnant, please consult your doctor before using Megazolid 600 Tablet . Your doctor will prescribe it only if the potential benefits justify the possible risks.

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Breast Feeding

Unsafe

Avoid taking Megazolid 600 Tablet if you are breastfeeding, as it may pass into breast milk and cause harmful effects in the baby.

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Driving

Unsafe

Megazolid 600 Tablet may cause dizziness and vision problems. So, drive only if you are alert.

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Liver

Caution

Dose adjustment may be necessary if you have liver impairment or disease. Please consult your doctor to discuss any concerns or to ensure safe and appropriate use.

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Kidney

Caution

Dose adjustment may be necessary if you have kidney impairment or disease. Please consult your doctor to discuss any concerns or to ensure safe and appropriate use.

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Children

Unsafe

Megazolid 600 Tablet is not recommended for children below 18 years of age.

Have a query?

FAQs

Megazolid 600 Tablet is an antibiotic medication used to treat bacterial infections of the skin and lungs (pneumonia). It is also used to treat infections that are resistant to other antibiotics, such as vancomycin-resistant enterococcal infections.

Megazolid 600 Tablet contains Linezolid (an antibiotic), which works by stopping the bacteria from making proteins necessary for their growth and multiplication, ultimately killing the bacteria. Thus, it helps treat the bacterial infection.

Diarrhoea might be a side effect of Megazolid 600 Tablet . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you have prolonged diarrhoea with abdominal pain, stop taking Megazolid 600 Tablet and consult your doctor. Do not take anti-diarrheal medicine on your own.

It is recommended to complete the course of Megazolid 600 Tablet even if you feel better as it is an antibiotic, and leaving it in between may lead to even severe infection. To treat your condition effectually, continue taking Megazolid 600 Tablet for as long as your doctor has prescribed it.

Megazolid 600 Tablet may cause thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.

Do not take Megazolid 600 Tablet on your own, as self-medication may lead to antibiotic-resistance, in which antibiotics fail to act against specific bacterial infections.

Megazolid 600 Tablet may affect certain laboratory test results, such as blood tests, blood sugar tests, liver and kidney function tests. Inform the person doing the tests that you are taking Megazolid 600 Tablet .

Megazolid 600 Tablet may cause anaemia due to a decrease in the number of red blood cells. This could also cause unexplained bleeding or bruising. Consult your doctor if you experience unexplained bleeding or bruising.

Consult your doctor before taking Megazolid 600 Tablet if you have hypertension (high blood pressure), as it may cause an increase in blood pressure.

You should avoid taking large quantities of food that contains high tyramine. Foods that are fermented, cured, aged or spoiled contain a high amount of tyramine, e.g. cheese, red wine, pickles, overripe fruits etc. Consuming tyramine while taking Linezolid can result in an elevation of blood pressure, which may result in an emergency.

You should take it twice a day, every 12 hours, for example, at 8 a.m. and 8 p.m. You can take it before, with, or after food. Your doctor or clinician will determine the duration of the treatment course.

Some foods containing tyramine can increase your blood pressure when taking this medicine. You should avoid the following types of foods include Mature or aged cheese, aged, smoked, pickled, or cured meats/fish/poultry such as salami, liver, pickled herring, chocolate (more than 50gm), avocados or any over-ripe fruit, broad beans, sauerkraut, sourdough bread, protein diet supplement etc.

Megazolid 600 Tablet may cause diarrhoea, which can be severe in some cases. It may occur two months or more after you stop taking it. Do not take any medicine to treat diarrhoea without first checking with your doctor. If you have any questions, check with your doctor.

Megazolid 600 Tablet is indicated for the treatment of gram-positive infections and is approved for treating skin and skin structure infections, bacterial pneumonia, and vancomycin-resistant enterococcal (VRE) infections, including those complicated by bacteremia.

Megazolid 600 Tablet disrupts bacterial growth by inhibiting the initiation process of protein synthesis.

It is usually taken with or without food or as directed by the doctor.

Common side effects of Megazolid 600 Tablet may include thrush (fungal infection), headache, metallic taste, diarrhoea, nausea, vomiting, dizziness, constipation, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Please consult your doctor. Megazolid 600 Tablet should be used during pregnancy or breastfeeding only if needed, and the benefit outweighs the risk to the fetus.

Avoid consuming alcohol while taking Megazolid 600 Tablet , as it may cause increased dizziness.

Take the missed dose as soon as you remember, unless it is almost time for your next dose. In this case, skip the missed dose and take your next dose at the regular time. Never take a double dose to make up for a missed one.

Country of origin

India

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.
Other Info - MEG0354

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