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compositionComposition:DINOPROSTONE-0.5MG
prescription
Prescription Medicine
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Medidin Gel is used to prepare the cervix for the initiation of labour in pregnant women. It contains Dinoprostone, which stimulates uterine muscles and increases the contractions of the uterus. This medicine may sometimes cause side effects such as back pain, vomiting, diarrhoea, flushing of the skin, and foetal distress. Inform the doctor if you are taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

DINOPROSTONE-0.5MG

Manufacturer/Marketer :

Medipol Pharmaceutical India Pvt Ltd

Consume Type :

Vaginal

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Medidin Gel

Medidin Gel is a specialized vaginal medication used to prepare and soften the cervix (the neck of the womb) for labour induction in pregnant women. It is prescribed when childbirth needs to be started medically at or near the delivery date. This preparation makes it easier for the cervix to open, helping to facilitate a smoother delivery process.

Unlike routine medications, this treatment is typically given as a single application by a healthcare professional in a hospital setting. Because it is inserted vaginally, food does not affect how it works, and no routine dietary changes are necessary before its use. Staying well-hydrated and resting comfortably are the best ways to support the process during its application.

Some women may experience mild stomach cramping, a warm sensation in the vagina, or mild nausea after insertion. However, you must inform your healthcare provider immediately if you experience severe abdominal pain, unusually strong or frequent contractions, or vaginal bleeding. These serious reactions require prompt medical attention to ensure both your and your baby's safety.

Do not take this if you have had a cesarean section or major uterine surgery in the past, or if you have been told your baby is in an unusual position for birth. Before receiving Medidin Gel, tell your doctor if you have a history of asthma, glaucoma, high blood pressure, liver damage, or kidney disease. This helps your medical team assess if this is the safest option for your delivery.

Medidin Gel can interact with other labour-inducing drugs, which is why they should not be used at the same time. Since it is designed specifically to start labour, its use is strictly limited to late-stage pregnancy under medical supervision, and it is not intended for breastfeeding or elderly individuals. Talk to your doctor or pharmacist if you have questions about how other substances might affect this treatment.

Uses of Medidin Gel

Medidin Gel is used in the management of Labour induction. The detailed uses of Medidin Gel are as follows:

  • Labour induction: It is used to kickstart the labour process when medical reasons require the delivery to begin before it starts naturally.
  • Cervical ripening: Medidin Gel helps soften, thin, and dilate the cervix in pregnant women who are at term, making the body ready for childbirth.

Key Benefits

Medidin Gel helps prepare the cervix for labour and supports the induction of childbirth when medically indicated. By promoting cervical ripening and helping labour progress, it supports a safer and more effective delivery process under medical supervision.
Benefits may include:

  • Helps soften and prepare the cervix for labour.
  • Supports the induction of labour when recommended by your doctor.
  • Promotes more effective progression of labour.
  • May help reduce the duration of labour in appropriate patients.
  • Increases the likelihood of a successful vaginal delivery when used as indicated.
  • Supports safe labour management under close medical supervision.
     
Side effects of Medidin Gel
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:
  • Talk to your doctor about your back pain and potential medication substitutes or dose changes.
  • Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
  • To lessen the tension on your back, sit and stand upright and maintain proper posture.
  • To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
  • Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
  • Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
  • To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
  • Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
  • Back discomfort can worsen by bending, twisting, and heavy lifting.
  • Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

Directions for Use

  • Medidin Gel is for vaginal use only.
  • It is not intended for self-application, as it is administered by a healthcare professional in a hospital setting at the appropriate time to help your cervix for labour.
  • Medidin Gel is applied directly to the cervix through the vagina using a specialized applicator. This is typically done while you are lying on your back.
  • After the application, you will need to remain lying down for 15 to 30 minutes, and possibly up to 2 hours, unless your doctor gives different instructions.

How Medidin Gel Works

Medidin Gel works by acting like the natural substances, called prostaglandins, that your body produces when it is ready to go into labour. When inserted into the vagina, it targets the tissues of the cervix directly. It helps break down the tough fibres in the cervix, causing it to soften, thin out, and begin to open. In addition to softening the cervix, this medication gently signals the muscles of the uterus to start contracting. These contractions help push the baby downward, further encouraging the cervix to dilate and helping your labour progress safely and naturally.
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Alcohol

Unsafe

No interactions were established.

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Pregnancy

Safe if prescribed

Medidin Gel is used to induce uterine contractions at delivery time. It is not for self-application purposes as usually applied in hospital settings under the supervision of medical healthcare professionals.

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Breast Feeding

Caution

Medidin Gel is most likely unsafe to use while breastfeeding. Based on limited human data, the drug may pass into breast milk and harm your infant.

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Driving

Unsafe

No interactions were established.

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Liver

Caution

Inform your doctor if you have liver problems before taking Medidin Gel. Your doctor will weigh the benefits and the risks before prescribing this medicine.

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Kidney

Caution

Medidin Gel can cause fluid retention if used in patients with kidney disease. Hence, inform your doctor if you have kidney problems before taking Medidin Gel. Your doctor will weigh the benefits and the risks before prescribing this medicine.

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Children

Unsafe

Medidin Gel is not recommended for children below the age of 18 years. The safety and effectiveness of Medidin Gel have not been established in children due to limited testing of this drug on children by competent authorities worldwide.

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Heart

Consult your doctor

Please inform your doctor if you have a history of heart disease before using Medidin Gel. Your doctor will prescribe it only if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Limited information available for use of Medidin Gel in elderly patients. Please consult your doctor.

What if I have taken an overdose of Medidin Gel

Because Medidin Gel is carefully measured and monitored by medical experts in a clinic, an overdose is highly unlikely. If your body reacts too strongly to the medicine, or if contractions become too intense, the medical team can immediately remove the insert or provide treatment to slow down the contractions.

Diet & Lifestyle Advise

  • Stay well hydrated: Drink plenty of water or clear fluids before your procedure, as staying hydrated helps support normal muscle function during contractions.
  • Eat light meals: Choose light, easily digestible meals before your hospital admission to help reduce the risk of nausea or stomach discomfort.
  • Practice breathing exercises: Use deep, rhythmic breathing techniques to help you stay relaxed and manage early cramps as the medicine begins to take effect.
  • Maintain a comfortable resting position: Keep a comfortable, supportive position while resting in bed during the recommended lying-down period after the medicine has been inserted.
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How Soon It Starts Working

The time required for Medidin Gel to start to work: Medidin Gel ideally shows its action within 10 minutes after insertion. The time for which the effects of Medidin Gel last: The effect of Medidin Gel lasts for 2 to 6 hours.

What if you forget to take Medidin Gel

Since this medication is inserted in a hospital setting by a healthcare professional as a single-use procedure, a missed dose is not possible. If the treatment needs to be repeated or adjusted, your clinical team will handle it directly.

Storage

• it must be kept frozen between -20°C and -10°C (-4°F to 14°F) or refrigerated between 2°C and 8°C (36°F to 46°F). •It must be kept in its original, moisture-resistant packaging until the moment it is ready to be used.

Drug Warnings

  • Do not insert or adjust the medicine yourself: Medidin Gel should only be inserted, removed, or adjusted by a qualified healthcare professional.
  • Do not pull or adjust the retrieval string: If a vaginal insert with a retrieval string is used, do not pull, tug, or adjust the string, as this may displace the medicine.
  • Expect close monitoring during treatment: Your baby's heart rate and your uterine contractions will be monitored regularly or continuously throughout treatment.
  • Report changes immediately: Inform your doctor or nurse right away if your water breaks or you experience a sudden gush or leakage of fluid.
  • Follow positioning instructions: Remain lying down for the length of time recommended by your healthcare team to help keep the medication in place and ensure it works effectively.

Drug-Drug Interactions

verifiedApollotooltip
  • Other labor-inducing medicines (e.g., oxytocin): Taking these medicines alongside Medidin Gel may cause excessively strong or frequent uterine contractions. Your doctor will carefully monitor and time these treatments if both are needed.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Medidin Gel when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[GYNECOLOGY RELATED DRUGS]

FAQs

Medidin Gel is used for the initiation or improvement of uterine contraction (antepartum) and producing uterine contraction during the third stage of labour (postpartum).
Medidin Gel contains a prostaglandin Dinoprostene that works by increasing the production of a natural substance called prostaglandins (PGs), which softens and widens the cervix (opening of the womb) and increases uterus contractions. As a result, these increased uterine contractions and widened cervix help deliver the child.
Medidin Gel is given as a suppository or a gel applied at a hospital only under strict medical supervision. The dose to be administered will be decided by your doctor, depending on your current medical situation.
The most common side effects of Medidin Gel include vomiting, back pain, diarrhoea, flushing of the skin, and fetal distress. You might also feel increased uterine contractions for some time, but these are manageable under medical supervision.
If you have a previous premature delivery or a c-section, or cervical surgery, please inform your doctor before starting Medidin Gel. Also, mention a detailed medical history to your doctor to avoid complications.
No, Medidin Gel should be taken in the dose and duration as advised by the doctor. If you take it in more than the recommended dose, it might cause unpleasant side effects like fetal distress or delivery complications.
It is advised to use Medidin Gel only if prescribed by a doctor as there are chances of increased complications in women aged 35 and above and if you smoke.
For some women, contractions may begin within a few hours of insertion, while for others, it gently prepares the cervix over a longer period before labour starts. Talk to your doctor.
The insertion process is similar to a standard pelvic exam and may cause brief discomfort, but it is generally not painful. Talk to your doctor or pharmacist.
If the insert slips out, tell your nurse or doctor immediately so they can check your progress and replace it if necessary. Talk to your doctor.
The vaginal insert version has a retrieval string that allows your healthcare provider to pull it out quickly if your contractions become too intense. Talk to your doctor.
Your clinical team will use external monitors placed on your abdomen to track your baby’s heart rate and the frequency of your contractions. Talk to your doctor or pharmacist.
If your cervix does not ripen or labour does not progress, your medical team will evaluate your situation and discuss alternative options, such as other medications or a cesarean delivery. Talk to your doctor.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

128/5, Swiss House, Vishwas Nagar, Delhi 110032 Delhi, India
Other Info - MEDI670
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