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  3. Mecofol Plus NF Injection 2 ml

Mecofol Plus NF Injection 2 ml, Pack of 1 INJECTION
Mecofol Plus NF Injection 2 ml, Pack of 1 INJECTION
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Mecofol Plus NF Injection 2 ml is a vitamin supplement which is used to treat nutritional deficiencies, vitamin B12 deficiency and vitamin B6 deficiency. It is a combination medicine which helps replenish energy, regulates many bodily functions, helps in the formation of red blood cells and provides essential nutrients that are required for the body growth and development. This medicine may cause common side effects like nausea, upset stomach, injection site reactions, numbness of your hands or feet and diarrhoea.
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Composition :

METHYLCOBALAMIN-1500MCG + NICOTINAMIDE-100MG + PYRIDOXINE HYDROCHLORIDE-100MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Mecofol Plus NF Injection 2 ml

Mecofol Plus NF Injection 2 ml belongs to the class of 'multivitamins' primarily used to treat and prevent nutritional deficiencies. Nutritional deficiencies occur when the body does not absorb or get enough vitamins, minerals, and antioxidants from food. Nutrient deficiency can lead to many health problems like a weakened immune system, indigestion, skin problems, heart problem, eye problems and defective bone growth.

Mecofol Plus NF Injection 2 ml contains Mecobalamin, Nicotinamide, and Pyridoxine hydrochloride. Mecobalamin regulates body functions like cell growth, blood formation, and protein synthesis. Nicotinamide is a form of vitamin B that provides vital nutrients. Pyridoxine hydrochloride is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters

Mecofol Plus NF Injection 2 ml will be administered by a health care professional. Do not self-administer. You may experience numbness of your hands or feet, upset stomach, diarrhoea, loss of hunger, and dizziness. Most of these side effects of Mecofol Plus NF Injection 2 ml do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are using prescription/non-prescription drugs or herbal products before starting Mecofol Plus NF Injection 2 ml. If you are known to be allergic to any of the components, please inform your doctor. Please tell your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food). If you are a pregnant or breastfeeding mother, please consult your doctor before taking Mecofol Plus NF Injection 2 ml.

Uses of Mecofol Plus NF Injection 2 ml

Treatment of Nutritional deficiencies, Vitamin B12 deficiency and Vitamin B6 deficiency.

Have a query?

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.• Mecofol Plus NF Injection 2 ml will be administered by the doctor or healthcare professional.• Do not self-administer.

Medicinal Benefits

Mecofol Plus NF Injection 2 ml belongs to the class of 'multivitamins' primarily used to treat nutritional deficiencies due to various complications or long-term diseases. It may be used to treat and prevent vitamin B6 deficiency, anaemia (lack of red blood cells), peripheral neuropathy (nerve disorder), seizures (fits), hereditary disorders like hyperoxaluria (excess oxalate levels in urine), and homocystinuria (accumulation of an amino acid called homocysteine in urine and blood). Mecofol Plus NF Injection 2 ml contains mecobalamin (vitamin B12), nicotinamide, and pyridoxine hydrochloride (vitamin B6). Mecobalamin (Methylcobalamin) is a coenzyme form of vitamin B12, which regulates body functions like cell growth, blood formation, and protein synthesis. Nicotinamide is a form of vitamin B that provides vital nutrients. Pyridoxine hydrochloride is involved in protein, fat, and carbohydrate metabolism, red blood cells, and neurotransmitter formation. Together, Mecofol Plus NF Injection 2 ml helps treat nutritional deficiencies.

How Mecofol Plus NF Injection 2 ml Works

Mecofol Plus NF Injection 2 ml contains Mecobalamin, Nicotinamide, and Pyridoxine hydrochloride. Mecobalamin regulates body functions like cell growth, blood formation, and protein synthesis. Nicotinamide is a form of vitamin B that provides vital nutrients. Pyridoxine hydrochloride is involved in protein, fat, and carbohydrate metabolism and the formation of red blood cells and neurotransmitters.

Storage

• Store in a cool and dry place away from sunlight.• Keep out of sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Mecofol Plus NF Injection 2 ml
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the six steps to manage medication-triggered Nervousness:
  • Tell your doctor immediately if you experience symptoms of Nervousness, such as anxiety, jitteriness, or an increased heart rate, after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen to alleviate symptoms of Nervousness. This can include switching to a different medication, reducing the dosage, or temporarily stopping the medication. Your doctor may also recommend alternative techniques like relaxation, mindfulness meditation, or journaling. These techniques can help reduce anxiety and Nervousness.
  • Practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling, to help manage Nervousness.
  • Engage in regular physical activity, such as walking or jogging, to help reduce anxiety and improve mood.
  • Your doctor may advise considering cognitive-behavioural therapy (CBT) or other forms of talk therapy to address underlying anxiety or Nervousness.
  • You should maintain regular follow-up appointments with your doctor to monitor nervousness symptoms, adjust treatment plans as needed, and discuss any concerns or questions.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

What if I have taken an overdose of Mecofol Plus NF Injection 2 ml

The overdose of Mecofol Plus NF Injection 2 ml is unlikely as it is administered by a doctor. However, if you suspect any adverse reactions or unusual symptoms while on treatment with Mecofol Plus NF Injection 2 ml, please inform your doctor immediately.

Drug Warnings

Let your doctor know if you are using prescription/non-prescription drugs or herbal products before starting Mecofol Plus NF Injection 2 ml. Inform your doctor if you are allergic to any of the components. Pyridoxine hydrochloride in Mecofol Plus NF Injection 2 ml is excreted into breast milk. Pregnant or breastfeeding women should consult their doctor before taking Mecofol Plus NF Injection 2 ml. This medicine should be given to children only when the doctor has prescribed it. Keep Mecofol Plus NF Injection 2 ml away from direct sunlight. Do not store Mecofol Plus NF Injection 2 ml above 25ºC and keep it away from direct sunlight.

Drug-Drug Interactions

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NicotinamidePitavastatin
Severe
NicotinamideLomitapide
Severe

Drug-Drug Interactions

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NicotinamidePitavastatin
Severe
How does the drug interact with Mecofol Plus NF Injection 2 ml:
Co-administration of Mecofol Plus NF Injection 2 ml with Pitavastatin can increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle).

How to manage the interaction:
Taking Mecofol Plus NF Injection 2 ml with Pitavastatin together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, contact a doctor immediately. Do not stop using any medications without consulting a doctor.
NicotinamideLomitapide
Severe
How does the drug interact with Mecofol Plus NF Injection 2 ml:
Coadministration of Mecofol Plus NF Injection 2 ml and Lomitapide can increase the risk of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Mecofol Plus NF Injection 2 ml and Lomitapide, but it can be taken if prescribed by a doctor. It is important to keep an eye out for any signs of liver damage. If you notice any symptoms like fever, joint pain, or loss of appetite, it's a good idea to contact a doctor right away. They can help determine if there is any liver damage and provide appropriate treatment. Do not discontinue any medications without consulting a doctor.
NicotinamideKetoconazole
Severe
How does the drug interact with Mecofol Plus NF Injection 2 ml:
Taking Mecofol Plus NF Injection 2 ml with Ketoconazole can increase the risk or severity of liver injury.

How to manage the interaction:
Taking Mecofol Plus NF Injection 2 ml with Ketoconazole together can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any symptoms of fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NicotinamideLeflunomide
Severe
How does the drug interact with Mecofol Plus NF Injection 2 ml:
Coadministration of Mecofol Plus NF Injection 2 ml with leflunomide can increase the risk or severity of liver problems.

How to manage the interaction:
Although there is an interaction between Mecofol Plus NF Injection 2 ml and leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
NicotinamideLovastatin
Severe
How does the drug interact with Mecofol Plus NF Injection 2 ml:
Coadministration of Mecofol Plus NF Injection 2 ml with Lovastatin can increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage.

How to manage the interaction:
Taking high-dose Mecofol Plus NF Injection 2 ml with Lovastatin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NicotinamideTeriflunomide
Severe
How does the drug interact with Mecofol Plus NF Injection 2 ml:
Coadministration of Mecofol Plus NF Injection 2 ml and Teriflunomide can increase the risk of liver damage.

How to manage the interaction:
Taking Mecofol Plus NF Injection 2 ml with Teriflunomide together can result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on any signs of liver problems. If you notice any symptoms like fever, joint pain, or loss of appetite, it's best to call a doctor right away. They can help determine if there is any liver damage or bleeding and provide the necessary treatment. Do not stop using any medications without a doctor's advice.
NicotinamideAtorvastatin
Severe
How does the drug interact with Mecofol Plus NF Injection 2 ml:
Coadministration of Mecofol Plus NF Injection 2 ml with Atorvastatin can increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage.

How to manage the interaction:
Taking Mecofol Plus NF Injection 2 ml with Atorvastatin together is used with caution as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NicotinamideSimvastatin
Severe
How does the drug interact with Mecofol Plus NF Injection 2 ml:
Coadministration of Mecofol Plus NF Injection 2 ml with Simvastatin can increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage.

How to manage the interaction:
Taking Mecofol Plus NF Injection 2 ml with Simvastatin together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any unexplained muscle pain, muscle stiffness or tenderness, fever, dark-colored urine, or weakness, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
NicotinamideMipomersen
Severe
How does the drug interact with Mecofol Plus NF Injection 2 ml:
Coadministration of Mecofol Plus NF Injection 2 ml and Mipomersen can increase the risk of liver damage.

How to manage the interaction:
Co-administration of Mecofol Plus NF Injection 2 ml with Mipomersen can result in an interaction, but it can be taken if your doctor has advised it. It is important to keep a close eye on any signs of liver problems. If you notice any symptoms like fever, joint pain, or loss of appetite, it's best to call a doctor right away. They can help determine if there is any liver damage and provide the necessary treatment. Do not stop using any medications without a doctor's advice.
NicotinamideRosuvastatin
Severe
How does the drug interact with Mecofol Plus NF Injection 2 ml:
Coadministration of Mecofol Plus NF Injection 2 ml with Rosuvastatin may increase the risk and severity of side effects like rhabdomyolysis (breakdown of skeletal muscle) or kidney damage which can be fatal.

How to manage the interaction:
Taking Mecofol Plus NF Injection 2 ml with Rosuvastatin together can result in an interaction, but it can be taken if your doctor has advised it. If you notice any symptoms like unexplained muscle pain, muscle stiffness or tenderness, fever, dark-coloured urine, or weakness, you should contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try Vitamin B complex food sources like milk, cheese, eggs, chicken, red meat, tuna, mackerel, salmon, shellfish, oysters, clams, dark green vegetables such as spinach and kale, beets, avocados, potatoes, whole grains, cereals, kidney beans, black beans, and chickpea.
  • Include fruits like citrus, banana, and watermelon in your diet.
  • Avoid smoking and alcohol consumption.
  • Exercise regularly, and maintain a healthy lifestyle. Avoid excess fatty foods.

Habit Forming

No

Therapeutic Class

NUTRITIONAL SUPPLEMENT

Mecofol Plus NF Injection 2 ml Substitute

Substitutes safety advice
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Alcohol

Caution

It is not known if alcohol interacts with Mecofol Plus NF Injection 2 ml. Consult a doctor if you have any concerns.

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Pregnancy

Caution

Let your doctor know if you are pregnant or planning to conceive before taking Mecofol Plus NF Injection 2 ml. Your doctor will weigh the risks and benefits before prescribing Mecofol Plus NF Injection 2 ml.

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Breast Feeding

Safe if prescribed

Please inform your doctor before taking Mecofol Plus NF Injection 2 ml if you are breastfeeding. Your doctor will weigh the risks and benefits before prescribing Mecofol Plus NF Injection 2 ml.

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Driving

Caution

Mecofol Plus NF Injection 2 ml does not affect your ability to drive.

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Liver

Caution

Let your doctor know if you have/had liver diseases before receiving Mecofol Plus NF Injection 2 ml.

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Kidney

Caution

Let your doctor know if you have/had kidney diseases before taking Mecofol Plus NF Injection 2 ml.

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Children

Caution

The doctor will prescribe the dosage of Mecofol Plus NF Injection 2 ml based on the child's age and weight. However, it is not advised in newborns and premature infants.

FAQs

Mecofol Plus NF Injection 2 ml belongs to the class of 'multivitamins' primarily used to treat and prevent nutritional deficiencies, including Vitamin B12 deficiency and Vitamin B6 deficiency.

Mecofol Plus NF Injection 2 ml is a vitamin supplement and consists of Pyridoxine hydrochloride (vitamin B6), Methylcobalamin (vitamin B12), and Nicotinamide. When you lack these vitamins, which cannot be recovered even with the food sources, Mecofol Plus NF Injection 2 ml helps normalize these deficient levels.

Vitamin B6 deficiency occurs when your body lacks adequate Pyridoxine levels. You can overcome this deficiency by including food sources rich in Pyridoxine, like milk, eggs, beef, pork, chicken or turkey, fish, peanuts, soya beans, wheat germ, oats, and bananas. If your Vitamin B6 levels are still low, your doctor may prescribe supplements.

Vitamin B12 deficiency is caused when you don't have enough Methylcobalamin or Mecobalamin levels in your body. You can include natural Vitamin B12 sources like eggs, beef, liver, chicken, trout, salmon, tuna fish, clams, fortified breakfast cereal, low-fat milk, yoghurt, and cheese in your diet for treating this deficiency. If you still have low levels of B12, please consult your doctor about its supplements.

Pyridoxine hydrochloride in this medicinemay interfere with laboratory tests like urine tests for urobilinogen. Please make sure your doctor and the laboratory staff know that you take Mecofol Plus NF Injection 2 ml before undergoing any blood and urine examinations.

Mecofol Plus NF Injection 2 ml is administered by a healthcare professional in a medical setting, usually at a hospital. So, it is not intended for self-administration.

The possible side effects of the Mecofol Plus NF Injection 2 ml may include stomach upset, loss of hunger, dizziness, constipation, and pain at the injection site. However, these symptoms vanish as your body adjusts to the medication. If these symptoms become worse, please consult a doctor for relief.

While taking Mecofol Plus NF Injection 2 ml, you can proceed with other medications if it is advised by the doctor. Certain medications, such as antibiotics, anticonvulsants, chemotherapy drugs, proton pump inhibitors, and some antidiabetic drugs, can interact with Mecofol Plus NF Injection 2 ml and lead to negative complications. To avoid this, inform about all ongoing medications to your doctor. The doctor can provide guidance on potential interactions and adjust your treatment accordingly.

Mecofol Plus NF Injection 2 ml should only be used during pregnancy and breastfeeding if needed and under a doctor's guidance. If you're pregnant or breastfeeding, inform your doctor before taking Mecofol Plus NF Injection 2 ml. Your doctor will discuss the benefits and risks and make an informed decision for you and your baby.

Store in a cool and dry place away from sunlight. Keep out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - MEC0312

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 7:00 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/mtm/pyridoxine.html
  2. https://www.drugs.com/mtm/methylcobalamin-vitamin-b12.html
  3. https://www.rxlist.com/niacinamide/supplements.htm

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