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Madopar 250 Tablet is used to treat Parkinson’s disease. It helps improve movement, reduces stiffness, and makes daily activities easier. It also helps control symptoms such as tremor (shaking) and slow movement.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Abbott India Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Madopar 250 Tablet

Madopar 250 Tablet is used to treat Parkinson’s disease. Parkinson’s disease is a disorder of the central nervous system that affects movement and locomotion. It causes stiffness, tremors (shaking), difficulty with walking, coordination, and balance.

Madopar 250 Tablet contains levodopa and benserazide, which work together to manage symptoms of Parkinson’s disease. It helps improve movement control and reduces stiffness and slowness. It also supports smoother body movements during daily activities. Together, Madopar 250 Tablet helps improve mobility (movement) and overall quality of life.

Take Madopar 250 Tablet as prescribed by your doctor. The common side-effects of Madopar 250 Tablet are Involuntary jerking movements of the body, agitation, hallucinations (seeing or hearing things that are not true), nausea, vomiting, loss of appetite, weight gain, constipation, skin rash, itching, confusion, tiredness, water retention, and difficulty sleeping or sudden onset of sleep episodes. If any of these side effects persist or worsen, inform your doctor immediately.

It is not recommended to take Madopar 250 Tablet if you are allergic to any of its contents. Madopar 250 Tablet is not recommended for use in individuals younger than 25 years, pregnant women, or breastfeeding mothers. Madopar 250 Tablet should be used with caution in the elderly, as dose adjustments may be necessary.

Uses of Madopar 250 Tablet

Madopar 250 Tablet is used in the treatment of Parkinson’s disease. The detailed uses of Madopar 250 Tablet are as follows:

  • Parkinson’s disease: Madopar 250 Tablet improves muscle control and reduces symptoms like tremors, stiffness, and slow movement.

Key Benefits

  • It helps reduce tremors (shaking), stiffness, and slow movement.
  • Improves muscle control and coordination.
  • Enhances voluntary movement and walking ability.
  • Makes daily activities easier to perform.
  • Helps relax rigid muscles.
  • Improves flexibility and overall physical comfort.

Directions for Use

  • Take Madopar 250 Tablet with or without food as advised by your doctor.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow it as a whole with a glass of water.
  • Do not crush, chew, or break it.

How Madopar 250 Tablet Works

Madopar 250 Tablet contains Levodopa and Benserazide. • Levodopa is a dopamine agonist and acts by increasing the dopamine levels in the brain. Dopamine is a neurotransmitter (chemical messenger) present in the brain that is important for movement control. • Benserazide prevents levodopa breakdown and increases its effectiveness. • Together, Madopar 250 Tablet can effectively reduce the symptoms of Parkinson's disease.
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Alcohol

Caution

Avoid consumption of alcohol while taking Madopar 250 Tablet as it may lead to increased dizziness and drowsiness.

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Pregnancy

Safe if prescribed

Madopar 250 Tablet should not be taken by pregnant women as it may cause harmful effects to the unborn baby. Consult your doctor for further advice.

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Breast Feeding

Caution

Madopar 250 Tablet may cause harmful effects to the nursing baby when used by breastfeeding mothers. It is used only if the physician believes the benefits outweigh the risks.

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Driving

Unsafe

Madopar 250 Tablet may cause a sudden onset of sleepiness. It is advised against driving or operating heavy machinery while using Madopar 250 Tablet .

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Liver

Caution

Madopar 250 Tablet should be used with caution if you have a history of liver diseases. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Madopar 250 Tablet should be used with caution if you have a history of kidney diseases. The dose may be adjusted by your doctor as required.

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Children

Unsafe

Madopar 250 Tablet is not recommended for children as the safety and efficacy have not established.

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Heart

Caution

Madopar 250 Tablet can be used with caution in patients with heart disease. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Madopar 250 Tablet should be given with caution in elderly patients due to an increased risk of side effects. Dose adjustment may be required based on their health condition.

What if I have taken an overdose of Madopar 250 Tablet

Avoid exceeding the prescribed dose, as it may lead to adverse effects. Symptoms of adverse effects may include cardiac arrhythmia, confusion, insomnia, nausea, and vomiting. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Diet & Lifestyle Advise

Diet:

  • Limit high-protein foods as they may interfere with the action of medicine.
  • Choose whole-grain foods like whole-wheat bread, oats, brown rice, or pasta.
  • Eat balanced meals at regular times.

Digestive Health:

  • Include fibre-rich foods such as fruits, vegetables, and whole grains.
  • Fibre helps reduce constipation and supports gut comfort.

Fluids:

  • Drink enough water throughout the day to prevent dehydration.
  • Proper hydration helps reduce headaches and tiredness.

Daily Habits:

  • Avoid alcohol, as it can increase sleepiness.
  • Maintain a regular meal and sleep routine to support overall well-being

Have a query?

How Soon It Starts Working

  • The time required for Madopar 250 Tablet to start to work: Madopar 250 Tablet starts to show its action within 30 to 60 minutes of administration.
  • The time for which the effects of Madopar 250 Tablet last: Madopar 250 Tablet effect lasts for 4 to 6 hours.

What if you forget to take Madopar 250 Tablet

If you miss a dose of Madopar 250 Tablet , take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for the missed dose.

Storage

• Store in a cool and dry place away from sunlight.• Keep this medicine out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

  • Madopar 250 Tablet is not recommended for use in individuals younger than 25 years, pregnant women, or breastfeeding mothers.
  • Madopar 250 Tablet should be used with caution in the elderly, as dose adjustments may be necessary.
  • Before taking Madopar 250 Tablet , inform your doctor if you have hormonal problems, diabetes, heart problems, stomach ulcers, or osteomalacia (soft and weak bones).
  • Do not take this medication if you have been taking non-selective monoamine oxidase inhibitors (MAOIs) such as isocarboxazid or phenelzine within the past 14 days.
  • If you notice impulse control disorders such as gambling addiction, increased libido (sexual desire), sexual addiction, compulsive spending or buying, and binge eating, inform your doctor immediately. In such cases, the doctor may reduce the dose or stop the treatment based on your condition.

Drug-Drug Interactions

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Drug-Drug Interactions: Inform your doctor if you are taking any of the following medicines, as there may be an interaction.

  • Antidepressant medicines (Tranylcypromine, Isocarboxazid)
    Potential effect: May increase blood pressure and raise the risk of serious side effects.
  • Anticancer medicine (Procarbazine)
    Potential effect: May increase blood pressure and increase the risk of adverse effects.
  • Antipsychotic medicine (Amisulpride)
    Potential effect: May increase the risk and severity of side effects and also reduce the effectiveness of both medicines.
  • Antibiotic medicine (Linezolid)
    Potential effect: May increase blood pressure and raise the risk of side effects.
  • Breathing problem medicine–Anticholinergic (Glycopyrronium bromide)
    Potential effect: May significantly reduce the blood levels of Madopar 250 Tablet and lower its effectiveness.

Drug-Food Interactions:

  • High-protein foods & Alcohol: Avoid taking Madopar 250 Tablet with high-protein foods (such as meat) and avoid alcohol, as they may reduce the medicine’s effect and increase side effects.

Drug-Disease Interactions: Madopar 250 Tablet should not be used in patients with the following conditions.

  • Glaucoma (increased pressure in the eye)
  • Liver problems
  • Kidney problems
  • Heart problems
  • Hyperthyroidism (overactive thyroid)
  • Severe mental illness
  • Skin cancer
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIPARKINSON AGENTS]

FAQs

Madopar 250 Tablet is used to treat Parkinson's disease, a disorder of the central nervous system that affects movement and locomotion.

Madopar 250 Tablet contains Levodopa and Benserazide, which is used to treat Parkinson's disease. Levodopa works by increasing dopamine levels, a chemical messenger present in the brain that causes symptoms of Parkinson's disease. Benserazide prevents the breakdown of Levodopa, thereby improving its efficacy.

Madopar 250 Tablet can cause drowsiness. Some patients taking this medicine may also experience a sudden onset of sleepiness without any warning signs. So, it would be best if you refrained from activities that require you to stay alert, such as driving or operating heavy machinery.

Madopar 250 Tablet may alter the test results of some blood or urine tests. It is essential to inform your doctor before undergoing any laboratory tests.

Madopar 250 Tablet is not recommended for patients with glaucoma (optic nerve damage due to increased intraocular pressure) because it may increase intraocular pressure.

Inform your doctor if you notice any impulsive behaviours such as the urge to eat, gamble, spend money, or increased sexual desire. Madopar 250 Tablet may cause drowsiness, so do not drive or operate heavy machinery.

The effects of Madopar 250 Tablet on bones with long-term use are not known. There is no clear evidence that Madopar 250 Tablet directly affects bones. Please consult a doctor if you have any concerns or require personalised advice.

Madopar 250 Tablet causes side effects such as nausea, vomiting, loss of appetite, diarrhoea, irregular heartbeat, weight gain, constipation, skin rashes, confusion, tiredness, and anemia (low number of red blood cells). Please consult a physician immediately if any of these side effects persist.

Disclaimer

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Country of origin

India

Manufacturer/Marketer address

401, LSC, C-Block, Mohan Place Saraswati Vihar Delhi DL 110034 In
Other Info - MAD0017
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