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compositionComposition:FINERENONE-10MG
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Prescription Medicine
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Lyvelsa 10 mg Tablet is used to treat Chronic kidney disease (CKD). It contains the active substance finerenone. It works by blocking the action of certain hormones (mineralocorticoids) that can damage your kidneys and heart. Common side effects of Lyvelsa 10 mg Tablet may include high potassium level (hyperkalaemia), weakness or tiredness, feeling sick (nausea), numbness in the hands and lips, decreased pulse rate, low sodium level (hyponatraemia), fatigue, headache, confusion, muscle weakness, spasms or cramps and high uric acid level (hyperuricaemia).

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

FINERENONE-10MG

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lyvelsa 10 mg Tablet

Lyvelsa 10 mg Tablet is a prescription medication used to lower the risk of kidney decline, kidney failure, heart attacks, and heart-related hospitalisations in adults with chronic kidney disease associated with type 2 diabetes. It is specifically designed to treat the progressive organ damage caused by these long-term conditions. By targeting specific pathways in the body, it helps preserve vital organ function.

To achieve the best results, you must take Lyvelsa 10 mg Tablet consistently once every day at the same time. This tablet can be taken with or without food, but you should choose one method and stick to it daily. Combining this treatment with lifestyle adjustments, such as adopting a low-sodium diet and engaging in doctor-approved exercise, can significantly improve your outcomes.

While taking Lyvelsa 10 mg Tablet , you may experience some side effects, with high blood potassium levels being the most common. It is crucial to monitor how you feel and consult your doctor immediately if you experience serious symptoms like severe muscle weakness, an irregular heartbeat, or extreme fatigue. Always consult your doctor if you experience any unusual or worsening symptoms.

Before starting this treatment, talk to your doctor if you have a history of liver damage, high potassium levels, or adrenal gland issues. Do not take this if you have adrenal insufficiency or if you are currently taking certain strong medications that interfere with this drug.This medicine is also not suitable for everyone. It is not approved for treating chronic kidney disease that is not associated with type 2 diabetes, and your doctor will assess whether it is appropriate for your condition before prescribing it.

This medicine can interact with certain other drugs, alcohol, and tobacco, which may increase the risk of side effects or reduce its effectiveness.If you are pregnant, planning to become pregnant, breastfeeding, or are able to become pregnant, talk to your doctor before starting Lyvelsa 10 mg Tablet . Your doctor may recommend using effective contraception during treatment if appropriate.

Uses of Lyvelsa 10 mg Tablet

Your doctor may prescribe Lyvelsa 10 mg Tablet to help manage the following conditions:

  • Chronic kidney disease associated with type 2 diabetes: Lyvelsa 10 mg Tablet helps by slowing down the progression of kidney damage, lowering the risk of complete kidney failure, and reducing the likelihood of needing dialysis or a kidney transplant.
  • Cardiovascular risks in diabetic kidney disease: Lyvelsa 10 mg Tablet helps by reducing the risk of heart attacks, cardiovascular-related death, and hospitalisations for heart failure in patients with existing kidney damage.

Key Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Protects Your Kidneys and Heart: By actively protecting your kidneys, Lyvelsa 10 mg Tablet helps keep these vital organs working efficiently for a longer period. This preservation of kidney function can delay or completely prevent the need for intensive treatments like dialysis, allowing you to maintain your independence and continue your daily routines with fewer disruptions.
  • Supports Heart and Kidney Health: Additionally, Lyvelsa 10 mg Tablet provides strong protection for your cardiovascular system, lowering the risk of sudden heart issues. Knowing that your heart and kidneys are receiving targeted protection helps ease the worry of unexpected hospitalisations, giving you the peace of mind to focus on living your life.
Side effects of Lyvelsa 10 mg Tablet
  • Limit fruit intake to two servings a day, choose a low-potassium options like apples and strawberries.
  • Restrict starchy vegetables like potatoes and pumpkin to half a cup daily.
  • Avoid or limit foods like tomato products, high-bran cereals, and salty or sugary snacks.
  • Limit dairy products to 200g of yoghurt or 300ml of milk per day.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.
  • Consume controlled amounts of salt to raise sodium levels.
  • Eat fresh fruits like apples, berries, oranges, mangoes, and bananas.
  • Include fresh vegetables like broccoli, sweet potatoes, beets, okra, spinach, peppers, carrots, and edamame.
  • Choose frozen vegetables without added butter or sauce.
  • Drink electrolyte beverages like sports drinks or electrolyte solutions to replenish sodium and other electrolytes.
  • Avoid excessive salt intake, but allow for controlled increases as needed.
  • Monitor and manage underlying health conditions that may contribute to hyponatremia.

Directions for Use

  • Lyvelsa 10 mg Tablet can be taken with or without food as advised by your doctor.
  • It is recommended to take Lyvelsa 10 mg Tablet once daily; however, follow your doctor's advice regarding the dosage and duration.
  • Swallow Lyvelsa 10 mg Tablet as a whole with water.
  • Do not crush, break or chew it.

How Lyvelsa 10 mg Tablet Works

Finerenone works by blocking specific docking sites in your body known as mineralocorticoid receptors. In people with chronic kidney disease and type 2 diabetes, these receptors are often overactivated by a hormone called aldosterone. When these receptors are constantly turned on, they trigger inflammation and cause scarring (fibrosis) in the tissues of your kidneys and heart. By blocking these receptors, Lyvelsa 10 mg Tablet acts as a protective shield, limiting harmful inflammation and tissue scarring to help slow down kidney damage and protect your heart from serious complications.
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Alcohol

Consult your doctor

It is not known if alcohol interacts with Lyvelsa 10 mg Tablet . Please consult the doctor.

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Pregnancy

Consult your doctor

You should not use this medication while pregnant unless your doctor says it is absolutely necessary.

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Breast Feeding

Unsafe

You should not breastfeed if you are on this medication. It might harm your child.

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Driving

Caution

Lyvelsa 10 mg Tablet has no effect on your ability to drive or use machines. But drive only if you are alert, as the Lyvelsa 10 mg Tablet may cause weakness or tiredness in some people.

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Liver

Caution

Caution should be exercised while using Lyvelsa 10 mg Tablet in patients with liver impairment. If you have a pre-existing or a history of liver disease, inform your doctor before taking the Lyvelsa 10 mg Tablet . Your doctor will weigh the benefits and potential risks before prescribing Lyvelsa 10 mg Tablet .

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Kidney

Safe if prescribed

Lyvelsa 10 mg Tablet can be taken safely if prescribed.

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Children

Unsafe

This medicine should not be given to children or teenagers under the age of 18 because it is not known whether it is safe and effective in this age group.

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Heart

Consult your doctor

Please consult your doctor before receiving Lyvelsa 10 mg Tablet if you have pre-existing heart problems. Your doctor will prescribe Lyvelsa 10 mg Tablet if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Lyvelsa 10 mg Tablet to geriatric patients. Your doctor will prescribe Lyvelsa 10 mg Tablet if the benefits outweigh the risks.

What if I have taken an overdose of Lyvelsa 10 mg Tablet

If you take too much of this medication, seek immediate medical attention or contact your local emergency services right away. An overdose can lead to dangerously high potassium levels, which require rapid medical treatment.

Diet & Lifestyle Advise

  • Limit high-potassium foods: Because Lyvelsa 10 mg Tablet can raise blood potassium levels, consult your dietitian or doctor about managing your intake of potassium-rich foods like bananas, avocados, spinach, and sweet potatoes.
  • Avoid potassium-containing salt substitutes: Do not use salt substitutes that contain potassium chloride, as they can cause a rapid, dangerous increase in your blood potassium levels.
  • Stay consistently hydrated: Drink the daily amount of water recommended by your kidney specialist. Dehydration can worsen kidney function and impact how your body processes this medication.
  • Monitor your blood pressure: Regularly check your blood pressure at home and keep a log for your doctor, as this helps track your response to the treatment.
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Have a query?

How Soon It Starts Working

  • The time required for Lyvelsa 10 mg Tablet to start to work: The time required for Lyvelsa 10 mg Tablet to show its action is not clinically established.
  • The time for which the effects of Lyvelsa 10 mg Tablet last: The duration of action for Lyvelsa 10 mg Tablet is not clinically established.

What if you forget to take Lyvelsa 10 mg Tablet

If you miss a dose, take it as soon as you remember on the same day. If it is already close to your next scheduled dose, skip the missed dose and resume your normal schedule. Do not take two doses at the same time to make up for a missed one.

Storage

• Store Lyvelsa 10 mg Tablet at room temperature, strictly between 20°C and 25°C (68°F to 77°F).

Drug Warnings

  • Avoid Grapefruit: Avoid consuming grapefruit or grapefruit juice while taking this medication, as it can interfere with how your body breaks down the drug and lead to increased side effects.
  • Regular Blood Tests: Attend all scheduled laboratory appointments. Your doctor must regularly check your blood potassium levels and kidney function to ensure the medication remains safe for you.
  • High Potassium May Require Treatment Changes: If your blood potassium level becomes too high (for example, above 5.5 mEq/L), your doctor may temporarily stop or adjust your Lyvelsa 10 mg Tablet treatment until it is safe to restart. Never change your dose on your own.
  • Tell Healthcare Providers: Inform all of your healthcare providers, including your dentist, that you are taking Lyvelsa 10 mg Tablet before you undergo any surgery or medical procedures.
  • Check Before New Medicines: Speak to your pharmacist or doctor before starting any new over-the-counter medications, herbal supplements, or vitamins, as many can interact with this drug.
  • Watch for serious symptoms: Monitor yourself for sudden swelling, rapid weight gain, or breathing difficulties, and report these changes to your doctor immediately.

Drug-Drug Interactions

verifiedApollotooltip
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): May significantly increase the levels of Lyvelsa 10 mg Tablet in your body, raising the risk of severe side effects.
  • Potassium supplements or potassium-sparing diuretics: May cause a dangerous accumulation of potassium in your blood.
  • Certain blood pressure medications (such as ACE inhibitors or ARBs): May increase the risk of high blood potassium levels.
  • Strong CYP3A4 inducers (such as rifampicin, carbamazepine, phenytoin, or St. John's Wort): May lower the amount of Lyvelsa 10 mg Tablet in your body, making the medicine less effective. These medicines are generally not recommended unless your doctor advises otherwise. 
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Grapefruit and grapefruit juice: May stop your body from properly breaking down Lyvelsa 10 mg Tablet , leading to high drug levels and increased toxicity risks.
  • Salt substitutes containing potassium: May directly cause dangerously high blood potassium levels when used during treatment.
     
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Lyvelsa 10 mg Tablet is used to treat patients with chronic renal damage caused by type 2 diabetes. It also lowered the occurrence of new-onset heart failure considerably.
Lyvelsa 10 mg Tablet contains the active substance finerenone. It works by blocking the action of certain hormones (mineralocorticoids) that can damage your kidneys and heart.
To treat your condition effectually, continue taking Lyvelsa 10 mg Tablet for as long as your doctor has prescribed. Your doctor may make this decision after checking your blood. Please do not stop taking Lyvelsa 10 mg Tablet without consulting your doctor.
CKD is typically caused by illnesses such as high blood pressure, diabetes, high cholesterol, kidney infections, renal inflammation, recurring kidney stones, an enlarged prostate, and long-term, regular use of certain medications such as lithium and nonsteroidal anti-inflammatory drugs (NSAIDs).
Chronic kidney disease (CKD) cannot always be avoided, but it can be reduced by controlling underlying illnesses such as diabetes or high blood pressure.
Taking too many painkillers (nonsteroidal anti-inflammatory medicines) or taking them longer than recommended can lead to chronic renal disease.
Tobacco use increases your risk of cardiovascular disease, such as heart attacks or strokes, which has been related to an elevated risk of chronic kidney disease (CKD).
Blood and urine tests can be used to detect chronic kidney disease (CKD). Other tests may be used to determine the extent of kidney injury. These may include an ultrasound, MRI, or CT scan, as well as a kidney biopsy.
When taking Lyvelsa 10 mg Tablet , it is important to avoid certain foods and substances that can interact with the medication, such as Grapefruit and Grapefruit Juice, High-Potassium Foods, and Alcohol. Always consult with your healthcare provider for personalized dietary advice and recommendations while taking Lyvelsa 10 mg Tablet .
Both medications have shown effectiveness in managing CKD and reducing the risk of complications. The choice between them may depend on individual patient factors, such as kidney function, blood pressure levels, and specific health conditions. Ultimately, the decision between Lyvelsa 10 mg Tablet and Farxiga should be made in consultation with your healthcare provider, who can consider your medical history and needs.
Yes, Lyvelsa 10 mg Tablet has been shown to improve kidney function in patients with chronic kidney disease (CKD) associated with type 2 diabetes. It works by blocking the effects of aldosterone, a hormone that can cause kidney inflammation and scarring. Clinical studies have demonstrated that Lyvelsa 10 mg Tablet can reduce the risk of kidney function decline, kidney failure, and cardiovascular complications.
Breastfeeding women should avoid taking Lyvelsa 10 mg Tablet . It is recommended to avoid breastfeeding during treatment with Lyvelsa 10 mg Tablet , as the medication may pass into breast milk and potentially harm the nursing infant.
Yes, Lyvelsa 10 mg Tablet has been shown to reduce the risk of heart failure events in high-risk patients. Clinical studies have demonstrated that Lyvelsa 10 mg Tablet can reduce the risk of cardiovascular death, non-fatal heart attacks, and hospitalization for heart failure in adults with chronic kidney disease (CKD) associated with type 2 diabetes. This makes it an effective option for managing kidney and heart health in high-risk patients.
Yes, Lyvelsa 10 mg Tablet can increase potassium levels in the body. This is a known side effect of the medication, and it is essential to monitor potassium levels regularly while taking Lyvelsa 10 mg Tablet . Your healthcare provider may adjust your dose or recommend additional monitoring to manage this risk.
Lyvelsa 10 mg Tablet is typically taken once daily. Following your healthcare provider's instructions regarding the dosage and frequency is essential. Your doctor may adjust the dose based on your kidney function and potassium levels.
Yes, Lyvelsa 10 mg Tablet can result in low blood pressure (hypotension), a known side effect of the medication. In clinical studies, low blood pressure occurred in a small percentage of patients taking Lyvelsa 10 mg Tablet . If you experience symptoms such as dizziness, lightheadedness, or fainting while taking this medication, it's important to consult your healthcare provider.
Yes, you can take Lyvelsa 10 mg Tablet with or without food. However, it is best to be consistent and take it the same way every day. Talk to your doctor if you have questions about how to take your medication.
Regular blood tests are necessary to monitor your kidney function and check the potassium levels in your blood, as this medication can cause potassium to build up. Talk to your doctor to understand how often you will need these tests.
You should avoid using salt substitutes that contain potassium, as combining them with Lyvelsa 10 mg Tablet can lead to dangerously high blood potassium levels. Talk to your doctor or pharmacist about safe seasoning alternatives.
Muscle weakness can be a sign of high potassium levels in your blood, which is a serious side effect of this medicine. If you notice muscle weakness, numbness, or an irregular heartbeat, contact your healthcare provider immediately. Talk to your doctor if you experience any unusual symptoms.
While Lyvelsa 10 mg Tablet blocks mineralocorticoid receptors similarly to some water pills (diuretics), it is not used as a primary water pill to treat swelling or fluid buildup. Instead, it is specifically prescribed to protect the kidneys and heart in people with diabetic kidney disease. Talk to your doctor for more details about how this medicine works for you.
There is limited information about the safety of Lyvelsa 10 mg Tablet during pregnancy. It is generally not recommended unless your doctor determines that the benefits outweigh the risks. Talk to your doctor immediately if you are pregnant, planning to become pregnant, or breastfeeding.

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Reference

  1. National Health Service (NHS). Kidney Disease - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Electronic Medicines Compendium (EMC). Pil.13438 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  3. MedlinePlus. A621038 Patient Information Monograph. Bethesda, MD: U.S. National Library of Medicine (NLM); 2025. [Accessed on 02 Jun. 2026]Check here
  4. Finerenone [Prescribing Information]. 2021. [Accessed on 24 Nov. 2022]Check here
  5. Central Drugs Standard Control Organization Central Drugs Standard Control Organization. [Accessed on 26 June 2023]Check here
  6. Kerendia 10 mg film coated tablets - Summary of Product Characteristics (SmPC) - (emc) [Internet]. Medicines.org.uk. 2024 [Accessed on 9 March 2024]Check here

Country of origin

India

Manufacturer/Marketer address

Plot No 107/108,Namli Block , Ranipool, East Sikkim 737135
Other Info - LYV0016
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