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compositionComposition:HUMAN INSULIN-100IU
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Prescription Medicine
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Lupisulin R (Regular) 100IU/ml Injection 3 ml is used in the treatment of type 1 and 2 diabetes mellitus. It contains Human Insulin, which works by suppressing the production of sugar in the liver and facilitating the reuptake of sugar in the fat and muscle cells, thereby maintaining consistent sugar control. Common side effects include low blood sugar, swelling in your hands or feet, weight gain, or thickening of the skin at the injection site. Before starting this medicine, inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

HUMAN INSULIN-100IU

Manufacturer/Marketer :

Lupin Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lupisulin R (Regular) 100IU/ml Injection 3 ml

Lupisulin R (Regular) 100IU/ml Injection 3 ml is an injectable medicine used to treat diabetes mellitus, including both type 1 and type 2 diabetes. It works by helping control high blood sugar levels in your body. Keeping your blood sugar managed is essential to prevent long-term health complications.

For best results, you must inject Lupisulin R (Regular) 100IU/ml Injection 3 ml consistently as directed by your healthcare provider, typically before meals. Making daily dietary changes, such as monitoring your carbohydrate intake, and engaging in regular physical activity are crucial parts of your treatment plan.

While injecting Lupisulin R (Regular) 100IU/ml Injection 3 ml, you may experience common side effects like mild low blood sugar or irritation at the injection site. However, if you experience serious symptoms such as severe low blood sugar, confusion, or a widespread allergic reaction, you must seek medical attention immediately.

Talk to your doctor before starting this medicine if you have a history of kidney disease, liver damage, or heart failure. Do not inject this medicine during episodes of low blood sugar or if you have a known allergy to any of its ingredients.

Certain substances, including alcohol, can interact with Lupisulin R (Regular) 100IU/ml Injection 3 ml and cause unpredictable changes in your blood sugar levels. If you are pregnant, breastfeeding, or an older adult, consult your doctor or pharmacist to ensure you are managing your dose safely.

Uses of Lupisulin R (Regular) 100IU/ml Injection 3 ml

Lupisulin R (Regular) 100IU/ml Injection 3 ml is used in the treatment of Type 1 and Type 2 diabetes mellitus. The detailed uses of Lupisulin R (Regular) 100IU/ml Injection 3 ml are as follows:

  • Type 1 Diabetes Mellitus: Lupisulin R (Regular) 100IU/ml Injection 3 ml helps replace the natural hormone your body cannot produce, which is necessary for controlling high blood sugar levels.
  • Type 2 Diabetes Mellitus: Lupisulin R (Regular) 100IU/ml Injection 3 ml helps lower blood sugar levels when oral medications and lifestyle changes are not enough to manage the condition.

Key Benefits

Lupisulin R (Regular) 100IU/ml Injection 3 ml helps support better blood sugar management by improving how your body controls glucose levels. Consistent use, along with a balanced diet and regular physical activity, can help maintain healthier blood sugar levels and support overall diabetes care.

Benefits may include:

  • Lupisulin R (Regular) 100IU/ml Injection 3 ml helps improve blood glucose control, reducing the risk of symptoms associated with high blood sugar, such as excessive thirst, frequent urination, fatigue, and blurred vision.
  • By helping keep blood sugar levels within the recommended range, Lupisulin R (Regular) 100IU/ml Injection 3 ml may reduce the risk of diabetes-related complications affecting organs such as the kidneys, nerves, eyes, and heart when used as part of a complete treatment plan.
  • Better blood sugar control may help reduce fluctuations in energy levels and support overall quality of life for people managing diabetes.

Directions for Use

  • Follow your doctor's instructions regarding the dosage and duration of treatment.
  • Lupisulin R (Regular) 100IU/ml Injection 3 ml should be administered subcutaneously (under the skin) in the abdomen, thigh or upper arm.
  • Rotate the injection site each time to prevent skin damage.
  • Never reuse needles or syringes and never share needles, syringes, cartridges, or pens.

How Lupisulin R (Regular) 100IU/ml Injection 3 ml Works

Lupisulin R (Regular) 100IU/ml Injection 3 ml acts as a replacement for the natural hormone normally produced by your pancreas. It facilitates the movement of sugar (glucose) from your bloodstream into your body's cells, where it is used for energy. Additionally, Lupisulin R (Regular) 100IU/ml Injection 3 ml helps stop your liver from releasing excess sugar into the blood, ensuring your levels remain within a stable, healthy range throughout the day.
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Alcohol

Unsafe

It is advised to avoid alcohol intake since it may worsen the side effects and increase the risk of developing low blood sugar levels.

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Pregnancy

Caution

It is advised to use Lupisulin R (Regular) 100IU/ml Injection 3 ml in pregnancy only if the benefit outweighs the risk. Please consult your doctor before starting Lupisulin R (Regular) 100IU/ml Injection 3 ml if you are pregnant or planning to conceive.

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Breast Feeding

Caution

Lupisulin R (Regular) 100IU/ml Injection 3 ml should be used in breastfeeding mothers only if clinically needed.

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Driving

Caution

Your driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience blurred vision, dizziness or drowsiness due to extremely low or high blood sugar.

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Liver

Caution

Lupisulin R (Regular) 100IU/ml Injection 3 ml should be used with caution in patients with liver diseases. Your doctor may adjust the dose of this medicine before prescribing it.

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Kidney

Caution

Lupisulin R (Regular) 100IU/ml Injection 3 ml should be used with caution in patients with kidney diseases. Your doctor may adjust the dose of this medicine before prescribing it.

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Children

Caution

Lupisulin R (Regular) 100IU/ml Injection 3 ml is not recommended for use in children below 2 years of age.

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Heart

Caution

Lupisulin R (Regular) 100IU/ml Injection 3 ml should be administered with caution in patients with heart problems. Please inform your doctor about any existing heart problems before using Lupisulin R (Regular) 100IU/ml Injection 3 ml.

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Geriatrics

Caution

Lupisulin R (Regular) 100IU/ml Injection 3 ml should be administered with caution in elderly patients. If you have any concerns, please consult your doctor.

What if I have taken an overdose of Lupisulin R (Regular) 100IU/ml Injection 3 ml

An overdose of Lupisulin R (Regular) 100IU/ml Injection 3 ml can lead to severe low blood sugar. If you are conscious and experience symptoms of low blood sugar, consume a fast-acting sugar source immediately (such as fruit juice, soda, or sugar candies). If the person is unconscious or unable to swallow, seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Diet: Maintain a consistent eating schedule and count your daily carbohydrates carefully to avoid sudden blood sugar spikes or drops.
  • Exercise: Engage in regular, moderate exercise, but check your blood sugar levels before, during, and after physical activity to ensure they remain safe.
  • Managing low blood sugar: Always carry a fast-acting source of sugar, such as glucose tablets or candy, with you at all times in case of sudden low blood sugar.
  • Blood sugar monitoring: Monitor your blood sugar levels regularly throughout the day and keep a log of your readings to share with your doctor.
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How Soon It Starts Working

The time required for Lupisulin R (Regular) 100IU/ml Injection 3 ml to start to work: Lupisulin R (Regular) 100IU/ml Injection 3 ml shows its action within 30 to 60 minutes of administration.

The time for which the effects of Lupisulin R (Regular) 100IU/ml Injection 3 ml last: Lupisulin R (Regular) 100IU/ml Injection 3 ml effects last for 6 to 8 hours.

What if you forget to take Lupisulin R (Regular) 100IU/ml Injection 3 ml

Check your blood sugar level immediately to determine your next step. If you are close to your next scheduled meal, consult your doctor or pharmacist for guidance. Do not inject a double dose to make up for a missed one, as this can cause dangerously low blood sugar.

Storage

• Store unopened vials or pens of Lupisulin R (Regular) 100IU/ml Injection 3 ml in the refrigerator between 2°C and 8°C.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the liquid before use: Do not inject Lupisulin R (Regular) 100IU/ml Injection 3 ml if it looks cloudy, contains clumps, or has changed colour (unless your specific type is supposed to be uniformly cloudy, as advised by your pharmacist).
  • Rotate injection sites: Always rotate your injection sites to prevent hard lumps or skin damage from developing under your skin.
  • Do not share injections: Never share your injection pens, syringes, or needles with anyone else, even if the needle has been changed, to avoid spreading infections.
  • Injection Safety: Always use a new, sterile needle for every single injection.
  • Medical Identification: Wear a medical identification bracelet or carry a card stating that you have diabetes and use Lupisulin R (Regular) 100IU/ml Injection 3 ml.

Drug-Drug Interactions

verifiedApollotooltip
  • Other diabetes medicines: May increase the risk of low blood sugar when used with Lupisulin R (Regular) 100IU/ml Injection 3 ml. Your doctor may need to adjust your medicines or monitor your glucose levels more closely.
  • ACE inhibitors: May enhance the blood sugar-lowering effect of Lupisulin R (Regular) 100IU/ml Injection 3 ml, which can increase the chance of hypoglycaemia (low blood sugar).
  • Beta-blockers: May hide some warning signs of low blood sugar, such as a fast heartbeat or palpitations, making it harder to recognise an episode early.
  • Corticosteroids: May reduce the blood sugar-lowering effect of Lupisulin R (Regular) 100IU/ml Injection 3 ml and may lead to higher blood glucose levels.
  • Thyroid medications: May affect blood sugar control in some people and may require closer monitoring when taken with Lupisulin R (Regular) 100IU/ml Injection 3 ml.
  • Atypical antipsychotics: May interfere with glucose regulation and can make blood sugar levels harder to control while using Lupisulin R (Regular) 100IU/ml Injection 3 ml.
Regular insulinOfloxacin
Severe

Drug-Drug Interactions

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Regular insulinOfloxacin
Severe
How does the drug interact with Lupisulin R (Regular) 100IU/ml Injection 3 ml:
The use of antibiotic (quinolones) has been linked to disruptions in blood glucose maintenance. There have been reports of both decrease in glucose and increase in glucose, mainly in diabetic individuals undergoing concurrent therapy with insulin or an oral antidiabetic medication.

How to manage the interaction:
Blood glucose should be closely watched, particularly if the patient is elderly, has renal impairment, or is very sick. When using insulin and insulin secretagogues (such as meglitinides and sulfonylureas) together, extra vigilance is suggested due to the possibility of severe and potentially hypoglycemia.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Can cause unpredictable fluctuations in your blood sugar levels and significantly increase your risk of severe low blood sugar. Avoid drinking alcohol on an empty stomach.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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FAQs

Lupisulin R (Regular) 100IU/ml Injection 3 ml is used to treat type 1 and type 2 diabetes mellitus.
Lupisulin R (Regular) 100IU/ml Injection 3 ml works by increasing the glucose uptake by fats and muscles, suppressing the production of glucose in the liver, and also the formation of glycogen from glucose. Thereby, Lupisulin R (Regular) 100IU/ml Injection 3 ml helps in reducing the glucose levels in the blood.
In hypoglycemia, blood sugar levels decrease significantly. It causes symptoms such as dizziness, headache, sweating, hunger, loss of consciousness, rapid breathing, or seizure (fits). In such cases, seek medical attention immediately.
If you experience low blood sugar, eat glucose tablets, chocolate, or another high-sugar snack, such as a sweet or biscuit. Use a blood glucose monitor to test your blood sugar levels after 15 minutes if possible.
Do not stop taking Lupisulin R (Regular) 100IU/ml Injection 3 ml without consulting your doctor on your own, as it may cause an increase in blood glucose levels. Continue taking Lupisulin R (Regular) 100IU/ml Injection 3 ml for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking Lupisulin R (Regular) 100IU/ml Injection 3 ml.
You are recommended to avoid white bread, maida, poori, naan, noodles, biryani, fried rice, corn flakes, cheese, ice creams, milkshakes, beef, pork, sugarcane juice, soft drinks, sweetened health drinks and beverages. Also, avoid mango, seetaphal, jack fruit, fruit salads with ice cream, and fruit-based desserts.
No, do not stop taking Lupisulin R (Regular) 100IU/ml Injection 3 ml without consulting your doctor as it may lead to high blood sugar levels and may worsen your condition resulting in complications. If you experience any side effects or discomfort, contact your doctor. You may need dose adjustment.
Taking an injection at the same site may cause local irritation, itching and lump formation. Therefore, it is best to avoid taking injections at the same site or maintain a gap of at least one day.
Maintain a diet that includes chapatis, puffed rice with vegetables, multigrain bread, plain cooked dal, roasted grams soups, sprouts, cooked vegetables with less oil, steamed vegetables, orange, jamun, guava, watermelon, apple, papaya, curd, cow’s milk, thin buttermilk, fish (baked, grilled, or steamed), cashew nuts, peanuts, and walnuts (handful). Avoid alcohol consumption and quit smoking. Exercise regularly and walk briskly daily for 30 minutes. Also, limit intake of sugar.
The risk factors for developing low blood sugar levels include not taking adequate meals or skipping meals, excessive insulin use, too much alcohol intake, fever and too much exercise. Some medications, like other diabetes medicines, glimepiride, medicines used for fever and pain (salicylates), ramipril, etc., can result in such episodes when used with insulin. Inform your doctor about these episodes, as you may need a dose adjustment.
It depends on whether you have type 1 diabetes mellitus or type 2. If you have type 1 diabetes, Lupisulin R (Regular) 100IU/ml Injection 3 ml should be used for the rest of your life as your body does not produce adequate insulin and the only treatment available is external source of insulin which cannot be stopped. However, if you have type 2 diabetes mellitus, the doctor may stop Lupisulin R (Regular) 100IU/ml Injection 3 ml if your blood sugar levels are well controlled with healthy diet, exercise and other diabetic medications. However, do not stop taking it on your own without consulting your doctor as it may worsen your condition.
Lupisulin R (Regular) 100IU/ml Injection 3 ml can be used with other diabetes medicines only if prescribed by a doctor. Thus, please consult a doctor before using Lupisulin R (Regular) 100IU/ml Injection 3 ml with other medicines.
Lupisulin R (Regular) 100IU/ml Injection 3 ml is injected under the skin in the areas such as thighs, buttocks, abdomen or upper arms. Never inject Lupisulin R (Regular) 100IU/ml Injection 3 ml into a muscle or vein. However, it is recommended to rotate your injection sites with each dose to reduce the risk of developing pitted or thick skin and lumps at the injection site. Inject Lupisulin R (Regular) 100IU/ml Injection 3 ml as shown by the doctor.
It is advised to take doctor’s advice before using Lupisulin R (Regular) 100IU/ml Injection 3 ml if you are pregnant or planning pregnancy. Your doctor will prescribe Lupisulin R (Regular) 100IU/ml Injection 3 ml if benefits are greater than the risks.
Yes, Lupisulin R (Regular) 100IU/ml Injection 3 ml is safe to use in type 2 diabetes if used as advised by the doctor. Monitor your blood sugar levels regularly. Your dosage may need to be changed as per your needs. Follow the lifestyle changes as advised by your doctor. Discuss with your doctor about the managing and preventing side effects.
The side effects of Lupisulin R (Regular) 100IU/ml Injection 3 ml include injection site reactions such as swelling, itching or redness, weight gain, and swelling due to fluid retention. Also, it may cause lipodystrophy (skin thickening or pits at the injection site). To avoid this side effect, rotate injection site for each dose.
Yes, Lupisulin R (Regular) 100IU/ml Injection 3 ml cause hypoglycaemia (low blood sugar) as the most common side effect. It occurs more frequently if you skip meals or delay food, drink alcohol, over-excessive or use other antidiabetic medications along with Lupisulin R (Regular) 100IU/ml Injection 3 ml. So, do not skip meals and be consistent in amount and timing of your meals. If you over exercise, take some snacks as per your requirement. It is important to monitor your blood sugar levels regularly. Always carry some fruit juice, sugary candies, glucose, or glucon-D with you. If you notice any fluctuations in your blood sugar levels, consult your doctor.
If you experience weight loss or gain, increased stress, illness, dietary changes such as missed meals or alcohol consumption, then you should consult your doctor for dose adjustment. If you have recently changed your workout routine or are taking any medicines, your dose may need to be changed. Also, lookout for certain side effects caused by Lupisulin R (Regular) 100IU/ml Injection 3 ml. Your doctor will advise you on how to prevent them. These side effects are usually temporary but if they are very severe, you may need dose adjustments.
Lupisulin R (Regular) 100IU/ml Injection 3 ml needs to be refrigerated before its first use. Unopened vials, disposable dosing devices and human insulin pens must be stored in a refrigerator where the temperature is between 2°C to 8°C. Do not freeze and do not use Lupisulin R (Regular) 100IU/ml Injection 3 ml that has been frozen. When the cartridge has been inserted into the injection pen, it should not be refrigerated and should be kept at room temperature, (below 30°C) and must be used within 28 days or be discarded, even if they still contain Lupisulin R (Regular) 100IU/ml Injection 3 ml.
Lupisulin R (Regular) 100IU/ml Injection 3 ml is a man-made version of human insulin, produced by a biotechnology method called recombinant DNA technology.
Consume a fast-acting sugar source immediately, like a glass of fruit juice, regular soda, or sugar candy. Recheck your blood sugar after 15 minutes. If it remains low, take another portion of sugar. Talk to your doctor or pharmacist if this happens regularly.
Most versions of Lupisulin R (Regular) 100IU/ml Injection 3 ml can be kept at room temperature (below 30°C) for up to 28 days once opened. Keep it away from direct heat and light. Talk to your doctor or pharmacist to confirm the exact storage limits for your specific product.
You should avoid or limit alcohol while using Lupisulin R (Regular) 100IU/ml Injection 3 ml. Alcohol can cause your blood sugar to drop unexpectedly and can hide the warning symptoms of low blood sugar. Always talk to your doctor before consuming alcohol.
Maintaining tight blood sugar control is crucial during pregnancy, and Lupisulin R (Regular) 100IU/ml Injection 3 ml is commonly used for this purpose. Your insulin requirements may change throughout your pregnancy, so you must talk to your doctor to manage your dose safely.
Mild irritation, redness, or itching can occur as your skin adjusts to the injections. This is usually temporary and resolves on its own. If the reaction is severe, spreads, or does not go away, talk to your doctor immediately.
Physical activity lowers blood sugar levels, so you may need to check your levels before, during, and after exercise. You might also need to eat a snack before working out. Talk to your doctor or pharmacist to learn how to adjust your treatment plan safely.
No, do not use Lupisulin R (Regular) 100IU/ml Injection 3 ml if it has been frozen, even if it has completely thawed. Freezing destroys the active protein in the medicine, making it ineffective. Safely discard the frozen product and start a new vial or pen.

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Country of origin

India

Manufacturer/Marketer address

Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Other Info - LUP0092
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