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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Lupin Mira-S 50 Tablet is used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, and dysuria (painful or difficult urination). It works by reducing the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. Additionally, it relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination.
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Manufacturer/Marketer :

Lupin Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lupin Mira-S 50 Tablet

Lupin Mira-S 50 Tablet is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, and dysuria (painful or difficult urination). Overactive bladder is a condition in which there is a problem with bladder function, which causes a sudden urge to urinate that might be difficult to control.
 
Lupin Mira-S 50 Tablet contains Solifenacin (anti-cholinergic) and Mirabegron (beta-3 adrenergic agonist). Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Lupin Mira-S 50 Tablet helps in treating overactive bladder.
 
You are advised to take Lupin Mira-S 50 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience common side-effects such as dry mouth, constipation, headache, high blood pressure, and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Lupin Mira-S 50 Tablet is not recommended for children as safety and efficacy have not been established. Lupin Mira-S 50 Tablet may cause blurred vision, so drive with caution. Avoid or limit alcohol consumption along with Lupin Mira-S 50 Tablet as it could lead to increased dizziness. Inform your doctor about your health condition and medications before taking Lupin Mira-S 50 Tablet to rule out any side effects/interactions.

Uses of Lupin Mira-S 50 Tablet

Treatment of Overactive bladder syndrome

Directions for Use

• Lupin Mira-S 50 Tablet can be taken with or without food, as advised by your doctor.• Follow your doctor's instructions on the dosage and timing of this medication.• Swallow the whole Lupin Mira-S 50 Tablet with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Lupin Mira-S 50 Tablet is a combination of two drugs, namely: Solifenacin and Mirabegron. Lupin Mira-S 50 Tablet is a combination medicine used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, dysuria (painful or difficult urination). Solifenacin is an anti-cholinergic that reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron is a beta-3 adrenergic agonist which relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Lupin Mira-S 50 Tablet helps in treating an overactive bladder.

How Lupin Mira-S 50 Tablet Works

Lupin Mira-S 50 Tablet contains Solifenacin (anti-cholinergic) and Mirabegron (beta-3 adrenergic agonist). Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Lupin Mira-S 50 Tablet helps in treating overactive bladder.

Storage

Keep Lupin Mira-S 50 Tablet out of reach and sight of children.

What if I have taken an overdose of Lupin Mira-S 50 Tablet

Take Lupin Mira-S 50 Tablet only as prescribed by the physician. Do not exceed the recommended dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Do not take Lupin Mira-S 50 Tablet if you are allergic to any of its contents. Inform your doctor if you have glaucoma, myasthenia gravis, ulcerative colitis, urinary retention, high blood pressure, angioedema, kidney or liver problems. Consult your doctor if you are pregnant or breastfeeding. Lupin Mira-S 50 Tablet is not recommended for children. Lupin Mira-S 50 Tablet may cause blurred vision, so drive with caution. Avoid or limit alcohol consumption with Lupin Mira-S 50 Tablet as it could lead to increased dizziness. 

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Lupin Mira-S 50 Tablet:
Taking Lupin Mira-S 50 Tablet and Potassium chloride together can increase the risk of stomach ulcers, bleeding, and stomach injury.

How to manage the interaction:
Taking Lupin Mira-S 50 Tablet with Potassium chloride is not recommended, as it can lead to an interaction, it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Lupin Mira-S 50 Tablet:
The blood levels and effects of Lupin Mira-S 50 Tablet may be greatly increased when combined with itraconazole.

How to manage the interaction:
Lupin Mira-S 50 Tablet and Itraconazole may interact, however, if recommended by a physician, they are safe to consume. Consult a doctor if you feel sleepy, or uneasy, have an irregular heartbeat, have blurry vision, have trouble urinating, have a dry mouth, a headache, have digestive problems, or have constipation. Without consulting a doctor, never stop taking any medication.
SolifenacinMesoridazine
Critical
How does the drug interact with Lupin Mira-S 50 Tablet:
Using Mesoridazine together with Lupin Mira-S 50 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Mesoridazine with Lupin Mira-S 50 Tablet is not recommended, please consult your doctor before taking it. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations call a doctor.
MirabegronEliglustat
Critical
How does the drug interact with Lupin Mira-S 50 Tablet:
Coadministration of Eliglustat and Lupin Mira-S 50 Tablet can significantly increase the blood levels of eliglustat. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Lupin Mira-S 50 Tablet with Eliglustat is not recommended, it should be taken only when advised by a doctor. You should seek immediate medical help if you develop symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, irregular heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Lupin Mira-S 50 Tablet:
Coadministration of Amiodarone with Lupin Mira-S 50 Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Amiodarone with Lupin Mira-S 50 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SolifenacinVandetanib
Severe
How does the drug interact with Lupin Mira-S 50 Tablet:
Coadministration of Vandetanib with Lupin Mira-S 50 Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Vandetanib with Lupin Mira-S 50 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lupin Mira-S 50 Tablet:
Taking carbamazepine and Lupin Mira-S 50 Tablet together may possibly reduce the effects of Lupin Mira-S 50 Tablet, which could reduce its capacity to treat the condition you have.

How to manage the interaction:
Although taking carbamazepine and Lupin Mira-S 50 Tablet together can possibly result in an interaction, it can be taken if your doctor has prescribed it. Inform your doctor if you use any other medications.
SolifenacinBedaquiline
Severe
How does the drug interact with Lupin Mira-S 50 Tablet:
Coadministration of Bedaquiline with Lupin Mira-S 50 Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Bedaquiline with Lupin Mira-S 50 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Lupin Mira-S 50 Tablet:
Coadministration of Sparfloxacin with Lupin Mira-S 50 Tablet can increase the risk of irregular heart rhythms.

How to manage the interaction:
Taking Sparfloxacin with Lupin Mira-S 50 Tablet together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
SolifenacinFosamprenavir
Severe
How does the drug interact with Lupin Mira-S 50 Tablet:
Coadministration of Lupin Mira-S 50 Tablet with Fosamprenavir may significantly increase the blood levels of Lupin Mira-S 50 Tablet.

How to manage the interaction:
There may be a possibility of interaction between Lupin Mira-S 50 Tablet and Fosamprenavir, but it can be taken if prescribed by a doctor. If you experience drowsiness, dizziness, irregular heartbeat, blurry vision, difficulty urinating, dry mouth, headache, gastrointestinal upset, or constipation, consult your doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Pelvic floor exercises would be helpful in treating bladder spasms.

  • Avoid foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, chocolate and tea. 

  • Avoid drinking excess alcohol or caffeinated drinks, as they can worsen the symptoms.

  • Maintain a healthy weight, and exercise regularly.

  • Quit smoking.

  • Take 6-8glasses of liquids every day.

  • Avoid processed foods. Instead, choose whole, unprocessed foods.

  • Include fruits, vegetables, and fibre-rich food in your diet.

Habit Forming

No

Therapeutic Class

ANTICHOLINERGICS
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Alcohol

Caution

You are recommended to avoid or limit alcohol consumption while taking Lupin Mira-S 50 Tablet as it may cause increased dizziness.

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Pregnancy

Caution

Limited information is available regarding the usage of Lupin Mira-S 50 Tablet during pregnancy. Consult your doctor before taking Lupin Mira-S 50 Tablet if you are pregnant.

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Breast Feeding

Caution

Limited information is available regarding the usage of Lupin Mira-S 50 Tablet during breastfeeding. Consult your doctor before taking Lupin Mira-S 50 Tablet if you are breastfeeding.

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Driving

Caution

Lupin Mira-S 50 Tablet may cause blurred vision and tiredness. Drive or operate machinery only if you are alert.

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Liver

Caution

Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Lupin Mira-S 50 Tablet is not recommended for children as safety and effectiveness have not been established.

Have a query?

FAQs

Lupin Mira-S 50 Tablet is used to treat overactive bladder (OAB) with symptoms of urinary incontinence (urine leakage), urgent or frequent urination, increased night-time urination, and dysuria (painful or difficult urination).

Lupin Mira-S 50 Tablet contains Solifenacin and Mirabegron. Solifenacin reduces the undesirable contractions of the bladder, thereby increasing the amount of urine that the bladder can hold. This decreases the urgency for urination. Mirabegron relaxes the muscles of the bladder; this prevents frequent, uncontrolled, or urgent urination. Together, Lupin Mira-S 50 Tablet helps in treating an overactive bladder.

There is some overlap between the symptoms of both OAB and BPH. OAB occurs due to uncontrolled urinary bladder muscle contractions. The main symptom of OAB is a sudden urge to urinate that's hard to control, which is stressful. On the other hand, BPH occurs due to an enlarged prostate gland, which puts pressure on the urinary bladder, thereby causing pain during urination.

Dry mouth could be a side effect of Lupin Mira-S 50 Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol; drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Lupin Mira-S 50 Tablet might cause hypertension. Therefore, consult your doctor before taking Lupin Mira-S 50 Tablet if you have high blood pressure.

Constipation could be a side-effect of Lupin Mira-S 50 Tablet . Eat fibre-rich food and drink plenty of fluids if you experience constipation. Talk to your doctor if you have severe constipation.

Country of origin

INDIA

Manufacturer/Marketer address

Lupin Ltd, 3Rd Floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India.
Other Info - LUP0369

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