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Lotensyl AT Tablet is used to treat hypertension (high blood pressure). It contains Atenolol and Lercanidipine which work by relaxing the blood vessels, slowing down the heart rate and making it easier for your heart to pump blood around your body. In some cases, this medicine may cause side effects such as nausea, tiredness, diarrhoea, and constipation. Let the doctor know if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Manufacturer/Marketer :

Sun Pharmaceutical Industries Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lotensyl AT Tablet

Lotensyl AT Tablet is a prescription medicine used to treat high blood pressure, also known as hypertension. It combines two different mechanisms to help keep your blood pressure within a healthy range, reducing the constant strain on your cardiovascular system. Lowering elevated blood pressure is crucial for preventing long-term complications, such as strokes and heart attacks.

For this medicine to work effectively, you must take Lotensyl AT Tablet consistently every day at the same time. It is best taken on an empty stomach, at least 15 minutes before breakfast or a meal, because food can significantly alter how the medicine is absorbed. Adopting a healthy diet and lifestyle changes, such as eating a low-salt diet and staying physically active, will also help you achieve the best possible results.

Like many blood pressure treatments, Lotensyl AT Tablet can cause some mild side effects like ankle swelling, headaches, or dizziness when you first start taking it. While these are often mild and temporary, you should consult your doctor immediately if you experience severe symptoms, such as a very slow heartbeat, breathing difficulties, or chest pain.

Do not take this if you have asthma, severe chronic obstructive pulmonary disease (COPD), severe kidney or liver damage, or certain heart conduction disorders. It is important to talk to your doctor before starting this medicine if you have a history of heart failure, diabetes, or poor blood circulation.

Lotensyl AT Tablet can interact with certain substances, such as alcohol, which can cause your blood pressure to drop too low, and grapefruit juice, which can dangerously increase the medicine's level in your blood. If you are pregnant, planning to become pregnant, breastfeeding, or are an older adult, you must consult your doctor before taking this medication to ensure it is safe for your specific situation.

Uses of Lotensyl AT Tablet

Lotensyl AT Tablet is used to lower high blood pressure and help reduce the risk of complications associated with uncontrolled hypertension. Its main uses include: 

  • High blood pressure (Hypertension): Lotensyl AT Tablet is used to lower high blood pressure, helping to reduce the overall workload on your heart and prevent damage to your blood vessels over time.
  • Prevention of heart attacks and strokes: By keeping your blood pressure within a normal, healthy range, this medicine helps lower your long-term risk of suffering a stroke, heart attack, or kidney damage.

Key Benefits

Lotensyl AT Tablet combines two medicines that lower blood pressure in complementary ways. Its main benefits include:

  • Provides effective blood pressure control: Atenolol slows the heart rate and reduces the force with which the heart pumps, while lercanidipine relaxes and widens the blood vessels. These combined actions help lower blood pressure when treatment with more than one medicine is needed.
  • Reduces strain on the heart: By lowering blood pressure and helping blood flow more easily, Lotensyl AT Tablet reduces the workload on the heart.
  • Helps protect the heart, brain, kidneys, and blood vessels: Maintaining good blood pressure control over time helps reduce the risk of damage to vital organs caused by persistently high blood pressure.
  • Supports long-term cardiovascular health: Regular use as prescribed, together with recommended diet and lifestyle changes, may help reduce the long-term risk of complications such as heart attack and stroke.

Directions for Use

  • Lotensyl AT Tablet can be taken with or without food as prescribed by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.
  • Swallow Lotensyl AT Tablet as a whole with a glass of water.
  • ¢ Do not chew, crush, or break it.

How Lotensyl AT Tablet Works

Lotensyl AT Tablet contains atenolol and lercanidipine, which work in different but complementary ways to lower blood pressure. Atenolol belongs to a group of medicines called beta-blockers. It blocks the effects of certain natural chemicals, such as adrenaline, on the heart. This slows the heart rate and reduces the force with which the heart pumps blood, helping to lower blood pressure and reduce the workload on the heart. Lercanidipine belongs to a group of medicines called calcium channel blockers. It reduces the entry of calcium into the muscle cells in the walls of blood vessels. This helps the blood vessels relax and widen, allowing blood to flow more easily and lowering blood pressure. Together, atenolol and lercanidipine help control blood pressure by reducing the heart's workload and relaxing the blood vessels.
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Alcohol

Caution

You are recommended not to consume alcohol with Lotensyl AT Tablet to avoid unpleasant side effects.

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Pregnancy

Caution

Lotensyl AT Tablet belongs to FDA Category C in pregnancy. There is limited evidence regarding the use of Lotensyl AT Tablet and is generally not preferred as the initial treatment of hypertension in pregnancy. It is best to consult your doctor if you have high blood pressures during pregnancy.

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Breast Feeding

Caution

Caution should be exercised, and it is advisable to consult a doctor before using it.

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Driving

Caution

Drive with caution. Lotensyl AT Tablet usually causes drowsiness and affects driving ability.

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Liver

Caution

Lotensyl AT Tablet to be taken with caution, especially if you have a history of Liver diseases/conditions. The dose may have to be adjusted by your doctor.

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Kidney

Unsafe

Lotensyl AT Tablet is not recommended for kidney failure patients or who are at a severe level of kidney damage. The dose may have to be adjusted by your doctor.

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Children

Caution

Lotensyl AT Tablet is not recommended for children below 12 years of age without a doctor's consent.

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Heart

Caution

Inform your doctor if you have any existing heart disease. Your doctor will prescribe this medicine only if the potential benefits outweigh the risks.

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Geriatrics

Caution

Lotensyl AT Tablet should be used in elderly patients only if prescribed by a doctor. If you have any concerns about using Lotensyl AT Tablet in older adults, please consult your doctor.

What if I have taken an overdose of Lotensyl AT Tablet

If you suspect an overdose or have taken too much of this medicine, seek immediate medical attention or go to the nearest emergency room. An overdose can cause your blood pressure to drop dangerously low and your heart rate to slow down severely, leading to deep dizziness, confusion, or fainting.

Diet & Lifestyle Advise

  • Limit your salt intake: Reduce the amount of salt in your diet, as excess salt can raise blood pressure. Limit processed and packaged foods, which may contain high amounts of hidden salt.
  • Avoid grapefruit and grapefruit juice: Grapefruit can increase the amount of lercanidipine in your bloodstream and raise the risk of side effects. Avoid grapefruit products while taking Lotensyl AT Tablet .
  • Limit alcohol consumption: Alcohol may increase the blood pressure-lowering effect of Lotensyl AT Tablet and worsen dizziness or light-headedness. Ask your doctor whether it is safe for you to drink alcohol while taking this medicine.
  • Stay physically active: Engage in regular activities such as walking, swimming, or cycling, as recommended by your doctor. Regular physical activity can support blood pressure control and overall heart health.
  • Stand up slowly: Rise gradually from a sitting or lying position, particularly when you first start treatment or after a dose change. This may help reduce dizziness, light-headedness, and the risk of falls.
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Have a query?

How Soon It Starts Working

The time required for Lotensyl AT Tablet to start to work: The time required for Lotensyl AT Tablet to show its action is unknown. The time for which the effects of Lotensyl AT Tablet last: The duration of action for Lotensyl AT Tablet is clinically unknown.

What if you forget to take Lotensyl AT Tablet

If you miss a dose of Lotensyl AT Tablet , take it as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Lotensyl AT Tablet tablets in their original packaging to protect them from moisture and direct light. • Keep all medicines in a secure place out of the sight and reach of children and pets.

Drug Warnings

  • Do not stop taking Lotensyl AT Tablet suddenly: Stopping atenolol abruptly may cause your blood pressure to rise or worsen chest pain, particularly if you have heart disease. If treatment needs to be stopped, your doctor will advise you how to reduce the dose gradually.
  • Monitor your blood pressure and pulse: Check your blood pressure and heart rate as advised by your doctor. Contact your doctor if your heartbeat is unusually slow or if you experience fainting, severe dizziness, unusual weakness, or persistent tiredness. Do not change your dose without medical advice.
  • Take care when driving: Lotensyl AT Tablet may cause dizziness, light-headedness, or tiredness, particularly when you first start treatment or after a dose change. Do not drive, operate machinery, or perform tasks requiring alertness until you know how the medicine affects you.
  • Avoid grapefruit and grapefruit juice: Grapefruit may increase the amount of lercanidipine in your bloodstream and raise the risk of side effects. Avoid grapefruit products while taking Lotensyl AT Tablet .
  • Tell healthcare professionals before a procedure: Inform your doctor, dentist, surgeon, or anaesthetist that you are taking Lotensyl AT Tablet before any medical or dental procedure, as atenolol may affect your response to certain medicines used during the procedure.

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The following medicines may interact with Lotensyl AT Tablet or affect how it works:

  • Other blood pressure-lowering medicines: Taking these medicines with Lotensyl AT Tablet may increase the risk of low blood pressure, dizziness, light-headedness, or fainting.
  • Medicines that affect heart rate or rhythm: Medicines such as digoxin, verapamil, or diltiazem may further slow the heart rate or affect the electrical signals that control the heartbeat when used with Lotensyl AT Tablet .
  • Non-steroidal anti-inflammatory drugs (NSAIDs): Pain-relieving medicines such as ibuprofen or naproxen may reduce the blood pressure-lowering effect of Lotensyl AT Tablet , particularly when used regularly. They may also affect kidney function in some people.
  • Certain antidepressants and antipsychotics: Some medicines used to treat depression or other mental health conditions may increase the blood pressure-lowering effect of Lotensyl AT Tablet and raise the risk of dizziness or fainting.
  • Medicines that affect the breakdown of lercanidipine: Certain antibiotics, antifungal medicines, antiviral medicines, and other medicines may increase the amount of lercanidipine in the bloodstream and raise the risk of side effects.

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The following foods and drinks may affect how Lotensyl AT Tablet works or increase the risk of side effects:

  • Grapefruit and grapefruit juice: Grapefruit may increase the amount of lercanidipine in the bloodstream and raise the risk of side effects, including an excessive fall in blood pressure. Avoid grapefruit products while taking Lotensyl AT Tablet .
  • High-fat meals: High-fat meals may increase the absorption of lercanidipine and raise the risk of side effects. Take Lotensyl AT Tablet at least 15 minutes before a meal, preferably before breakfast, unless your doctor advises otherwise.
  • Alcohol: Alcohol may increase the blood pressure-lowering effect of Lotensyl AT Tablet and worsen dizziness or light-headedness. Ask your doctor whether it is safe for you to drink alcohol during treatment.

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Lotensyl AT Tablet contains Atenolol (beta-blocker) and Lercanidipine (calcium channel blocker). Atenolol works by changing the way your body responds to some nerve impulses, including in the heart. It slows down your heart rate and makes it easier for your heart to pump blood around your body. Lercanidipine works by blocking calcium going into muscles in the heart and blood vessels. Muscles need calcium to contract, so when you block the calcium, it makes the muscle cells relax. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. Altogether, Lotensyl AT Tablet helps in lowering your raised blood pressure and in reducing the risk of having a stroke, a heart attack, other heart problems, or kidney problems in the future.
Even though your blood pressure becomes normal after using Lotensyl AT Tablet , it may switch back to high ranges if you stop using it. Your doctor may change the dosing schedule based on your blood pressure range.
Lotensyl AT Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.
High blood pressure during pregnancy is called 'Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of feet, kidney damage and a higher risk of bleeding during pregnancy and during delivery. This can also affect the baby by causes abnormal fetal heart rate of the baby, risk of stillbirth and small baby. So, during the pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns related to blood pressure during pregnancy.
Usually, Lotensyl AT Tablet is prescribed for a long term treatment ranging from weeks to months for treating heart-related conditions and disorders. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.
It is highly recommended to avoid or strictly limit alcohol while taking Lotensyl AT Tablet . Alcohol can cause your blood pressure to drop too low, which can make you feel extremely dizzy, lightheaded, or faint. Talk to your doctor.
Grapefruit contains compounds that block an enzyme responsible for breaking down lercanidipine in your body. This can cause the drug levels to rise dangerously high, leading to severe side effects like low blood pressure and a rapid heart rate. Talk to your doctor.
Take the missed dose as soon as you remember. However, if your next scheduled dose is less than 12 hours away, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one. Talk to your doctor.
You should consult your healthcare provider before taking non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen. NSAIDs can make Lotensyl AT Tablet less effective at lowering your blood pressure and may also increase the risk of kidney strain. Talk to your doctor.
Yes, ankle swelling is a known side effect of the lercanidipine component in Lotensyl AT Tablet . It happens because blood vessels relax and fluid can pool in your lower legs. If the swelling is severe or bothersome, do not stop taking the medicine on your own. Talk to your doctor.
The beta-blocker component in Lotensyl AT Tablet can mask the warning signs of low blood sugar, such as a rapid heart rate or shaking. You may need to monitor your blood sugar levels more closely while taking this medicine. Talk to your doctor.
Lotensyl AT Tablet is generally not recommended for use during pregnancy or while breastfeeding, as it may affect the baby's heart rate and development. If you are pregnant, planning to become pregnant, or breastfeeding, alternative blood pressure treatments should be discussed. Talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Sun Pharmaceutical Industries Ltd., SUN HOUSE, CTS No. 201 B/1, Western Express Highway, Goregaon (E), Mumbai 400063
Other Info - LOT0005
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