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  3. Losakind-H Tablet 10's

Losakind-H Tablet 10's, Pack of 10 TABLETS
Losakind-H Tablet 10's, Pack of 10 TABLETS
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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Losakind-H Tablet is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure. It is a combination medication generally used when a single medicine is unable to control high blood pressure. It contains Losartan and Hydrochlorothiazide, which helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Also, it prevents excess salt absorption in the body, preventing fluid retention. Thus, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload). In some cases, it may cause side effects such as upper respiratory infections, dizziness, feeling tired, nausea, diarrhoea, back pain, and cold/flu symptoms like a cough.

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Composition :

HYDROCHLOROTHIAZIDE-12.5MG + LOSARTAN-50MG

Manufacturer/Marketer :

Mankind Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Losakind-H Tablet

Losakind-H Tablet is used to treat hypertension (high blood pressure) and reduce the risk of stroke. Hypertension or high blood pressure is a life-long or chronic condition in which the force exerted against the artery wall becomes too high. It can lead to the risk of heart diseases like heart attack and stroke.

Losakind-H Tablet is a combination of Losartan and Hydrochlorothiazide. Losartan helps to relax and widen the blood vessels (arteries) for easy blood flow. Hydrochlorothiazide prevents excess salt absorption in the body, preventing fluid retention.

You may experience certain side effects like dizziness, feeling tired, nausea, diarrhoea, back pain, and cold/flu symptoms like a cough in some cases. Most of these side effects of Losakind-H Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

You can take Losakind-H Tablet with food or on an empty stomach. It should be swallowed whole with a glass of water. Your doctor will advise you on how often you take your tablets based on your medical condition. Do not chew, break, or crush the medicine.

Inform your doctor if you are allergic to Losakind-H Tablet . Do not use potassium supplements or salt substitutes unless your doctor tells you. Consult your doctor if you are pregnant or breastfeeding. Besides this, you should not use the Losakind-H Tablet if you cannot urinate.

Uses of Losakind-H Tablet

Losakind-H Tablet is used in the treatment of Hypertension (high blood pressure) and prevention of stroke. The detailed uses of Losakind-H Tablet are as follows:

  • Hypertension: Losakind-H Tablet controls blood pressure more effectively than either drug alone
  • Stroke Prevention: Losakind-H Tablet is used especially in patients with left ventricular hypertrophy (enlarged heart muscle).
  • Heart Failure & Cardiovascular Risk Reduction: Losakind-H Tablet help reduce the risk of heart attack and other complications.

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Directions for Use

  • Take Losakind-H Tablet with or without food as advised by your doctor.
  • It is advised to take Losakind-H Tablet once daily in the morning; however, follow your doctor’s recommendation regarding the dosage and duration.
  • Swallow Losakind-H Tablet as a whole with a glass of water.
  • Do not crush, chew or break it.

Medicinal Benefits

  • Losakind-H Tablet contains losartan (angiotensin II receptor antagonist) and hydrochlorothiazide (a thiazide diuretic or water pill).
  • Losartan widens the blood vessels (arteries) for easy blood flow, whereas hydrochlorothiazide prevents fluid retention.
  • This medicine lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid retention).
  • This combination medication is generally used when a single medicine is unable to control high blood pressure.

How Losakind-H Tablet Works

Losakind-H Tablet is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together, it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload).

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Losakind-H Tablet
  • Regular exercise increases nitric oxide, relaxing blood vessels and improving circulation.
  • Avoid smoking and alcohol consumption as they can damage blood vessels and worsen vasodilation.
  • Foods high in omega-3 fatty acids such as walnuts, flaxseeds and fatty fish improve cardiovascular health and lower inflammation.
  • Limit the amount of salt in your regular diet.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Avoid driving or operating machinery or activities that require high focus until you know how the medication affects you.
  • Maintain a fixed sleeping schedule, create a relaxing bedtime routine and ensure your sleeping space is comfortable to maximize your sleep quality.
  • Limit alcohol and caffeine as these may worsen drowsiness and disturb sleep patterns.
  • Drink plenty of water as it helps with alertness and keeps you hydrated and for overall well-being.
  • Moderate physical activity can improve energy levels, but avoid intense workouts right before bedtime.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the 7 step-by-step strategies to manage the side effect of "inability to sleep" caused by medication usage:
  • Prepare for a restful night's sleep: Develop a calming pre-sleep routine, like reading or meditation, to help your body relax and prepare for sleep.
  • Create a sleep-conducive Environment: Make bedroom a sleep haven by ensuring it is quiet, dark and calm.
  • Follow a Sleep Schedule: Go to bed and get up at the same time every day to help regulate your body's internal clock and increase sleep quality.
  • Try relaxing techniques like deep breathing, mindfulness meditation and any others.
  • Limit stimulating activities before bedtime: Avoid stimulating activities before bedtime to improve sleep quality.
  • Monitor Progress: Keep track of your sleep patterns to identify areas for improvement.
  • Consult a doctor if needed: If these steps don't improve your sleep, consult a doctor for further guidance and therapy.
  • Drink warm fluids such as warm water with honey, broth, soup or herbal tea to soothe sore throat.
  • Gargle with warm salt water.
  • Suck on lozenges to increase the production of saliva and soothe your throat.
  • Use a humidifier to soothe sore throat as it adds moisture to the air and makes breathing easier.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Losakind-H Tablet

Do not take more than the prescribed dose of Losakind-H Tablet as it may cause overdose. The symptoms of overdose include sleepiness, papitations (pounding heartbeat) and dizziness. If you suspect you have taken overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

  • Losakind-H Tablet should not be given to the people allergic to Losakind-H Tablet .
  • It should be used with caution in patients who have diabetes. 
  • Losakind-H Tablet is not recommended in conditions like low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem).
  • Do not consume alcohol with Losakind-H Tablet as it may increase the risk of low blood pressure.
  • Avoid potassium supplements with Losakind-H Tablet as they may lead to high potassium levels in the blood.
  • Regular blood tests and blood pressure monitoring are recommended while taking Losakind-H Tablet .
  • Drink a lot of fluids, as Losakind-H Tablet can cause dehydration, so to avoid unpleasant side effects, increase the intake of fluids.
  • This medicine is not recommended for use in pregnant women, as it can cause fetal harm. Hence, inform your physician if you are pregnant or breastfeeding.

Drug-Drug Interactions

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HydrochlorothiazideCisapride
Critical
HydrochlorothiazideDofetilide
Critical

Drug-Drug Interactions

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HydrochlorothiazideCisapride
Critical
How does the drug interact with Losakind-H Tablet:
Taking Cisapride and Losakind-H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Losakind-H Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Losakind-H Tablet:
Taking Dofetilide and Losakind-H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Losakind-H Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideArsenic trioxide
Severe
How does the drug interact with Losakind-H Tablet:
Co-administration of Arsenic trioxide and Losakind-H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Arsenic trioxide and Losakind-H Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideZiprasidone
Severe
How does the drug interact with Losakind-H Tablet:
Taking Ziprasidone and Losakind-H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Ziprasidone and Losakind-H Tablet together is avoided as it can possibly result in an interaction, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideLithium
Severe
How does the drug interact with Losakind-H Tablet:
Coadministration of Lithium and Losakind-H Tablet can increase the effects of lithium.

How to manage the interaction:
Taking Lithium and Losakind-H Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like loose stools, vomiting, drowsiness, shaking of hands and legs, thirst, increased urination, lack of coordination, or muscle weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideDolasetron
Severe
How does the drug interact with Losakind-H Tablet:
Co-administration of Dolasetron and Losakind-H Tablet can affect the rhythm of your heart which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Dolasetron and Losakind-H Tablet together is avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like irregular heartbeat, chest tightness, blurred vision, nausea, and seizures, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazidePimozide
Severe
How does the drug interact with Losakind-H Tablet:
The combined use of Pimozide and Losakind-H Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Pimozide and Losakind-H Tablet together can possibly result in an interaction, but it can be taken if advised by your doctor. However, consult the doctor immediately if you experience any symptoms like dizziness, lightheadedness, fainting, fast heartbeats, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideTizanidine
Severe
How does the drug interact with Losakind-H Tablet:
The combined use of Tizanidine and Losakind-H Tablet can have additive effects in lowering your blood pressure.

How to manage the interaction:
Taking Tizanidine and Losakind-H Tablet together can possibly result in an interaction, but they can be taken if advised by your doctor. However, if you experience any symptoms like headache, dizziness, lightheadedness, fainting, and changes in pulse or heart rate, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydrochlorothiazideAmiodarone
Severe
How does the drug interact with Losakind-H Tablet:
Coadministration of Amiodarone together with Losakind-H Tablet may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Losakind-H Tablet interact, they can be used if prescribed by a doctor. If you have cardiac problems or electrolyte imbalances, you may be at greater risk. If you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, Weakness, tiredness, drowsiness, confusion, painful muscle cramping, dizziness, nausea, or vomiting, get medical attention. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideAminolevulinic acid
Severe
How does the drug interact with Losakind-H Tablet:
Coadministration of Aminolevulinic acid with Losakind-H Tablet can make your skin more sensitive to bright lights. This could increase the risk or severity of developing a sunburn.

How to manage the interaction:
Although there is a possible interaction between Aminolevulinic acid and Losakind-H Tablet, it can be taken if advised by your doctor. Avoid exposure of the eyes and skin to sunlight or bright indoor lights for 48 hours. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Keep your weight under control with a BMI of 19.5-24.9.
  • Do regular physical activity or exercise for at least 150 minutes per week, or about 30 minutes most days of the week. Doing this can help you to lower your raised blood pressure by about 5 mm of Hg.
  • Limit sodium chloride (table salt) intake in your daily diet to 2300 mg per day or less than 1500 mg is ideal for most adults.
  • If you are taking alcohol, then only one serving for women and two servings is advisable.
  • Quitting smoking is the best strategy to lower the risk of heart disease.
  • Avoid chronic stress as it can raise your blood pressure. Try to enjoy and spent time with your loved ones to cope with stress and practice mindfulness techniques.
  • Monitor your blood pressure daily and if there is too much fluctuation, then immediately contact your doctor.
  • Try to include heart-healthy omega-3 fatty acids containing food drinks in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil, and coconut oil to lower your elevated blood pressure.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Losakind-H Tablet Substitute

Substitutes safety advice
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Alcohol

Unsafe

You are recommended not to consume alcohol and Losakind-H Tablet to avoid unpleasant side effects like drowsiness, dizziness, and liver damage.

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Pregnancy

Unsafe

Losakind-H Tablet is not recommended during pregnancy as it may cause fetal damage and can affect the unborn baby (fetus).

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Breast Feeding

Consult your doctor

Losakind-H Tablet is known to pass breast milk, but its effect on the baby is unknown. So, before breastfeeding, let your doctor know about this.

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Driving

Unsafe

Losakind-H Tablet causes drowsiness and dizziness, so drive only if you are alert.

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Liver

Caution

Losakind-H Tablet to be taken with caution, especially if you have or have had a history of liver disease. Your doctor will adjust the dosage depending on your medical condition and your reaction to treatment.

bannner image

Kidney

Unsafe

Losakind-H Tablet is not recommended in patients with chronic kidney disease (severe renal impairment). Safety and effectiveness in patients with severe renal impairment have not been established.

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Children

Unsafe

Losakind-H Tablet is not recommended for use in children below 18 yaers of age as the safety and efficacy are not established.

FAQs

Losakind-H Tablet is used to treat hypertension (high blood pressure) and reduce the risk of stroke in patients with high blood pressure.

Losakind-H Tablet is a combination of Losartan (angiotensin II receptor antagonist) and Hydrochlorothiazide (thiazide diuretic or water pill). Losartan is an angiotensin receptor blocker that helps to relax and widen the blood vessels (arteries) for easy blood flow to the whole body. Hydrochlorothiazide is a diuretic that prevents excess salt absorption in the body, preventing fluid retention. Together it lowers blood pressure and prevents the risk of stroke, heart attack, and oedema (fluid overload).

No, you are advised to inform your doctor and monitor your blood pressure for at least two weeks before stopping the medicine. Depending upon your current blood pressure readings, there is a possibility your doctor may lower your medicine dosage and not recommend to discontinue it.

Losakind-H Tablet can be safely taken as long as your doctor has prescribed it to you. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor.

In case you have missed a dose of Losakind-H Tablet , you are advised to take it as soon as you remember. However, try not to miss a dose in the first place; if it's time for you to take your next dose, then do not take both the doses together. Take only one dose; taking a double dose of Losakind-H Tablet will lead to low blood pressure.

It is not recommended to take Losakind-H Tablet if you are pregnant as it can damage the unborn baby (may lead to fetal toxicity).

Yes, prolonged intake of Losakind-H Tablet can cause an increase in blood potassium level. So, patients taking Losakind-H Tablet should avoid taking supplements and food rich in potassium to avoid any unpleasant side-effect.

Yes, Losakind-H Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Losakind-H Tablet . In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.

You should not take Losakind-H Tablet if you have ever had liver disease, kidney failure, glaucoma, high or low levels of magnesium or potassium in your blood, have allergies or asthma, lupus (an autoimmune disease), diabetes, anuria (reduction or absence of urine) and pregnant women in their second or third trimesters. Besides this, avoid using Losakind-H Tablet (in case of diabetes) with aliskiren (a blood pressure medicine) as it can lead to a life-threatening condition.

Country of origin

India

Manufacturer/Marketer address

208, Okhla Industrial Estate, Phase III, New Delhi - 110020
Other Info - LOS0015

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Aug 8, 2025 | 2:07 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.drugs.com/uk/pdf/leaflet/896556.pdf
  2. https://www.drugs.com/hyzaar.html
  3. https://www.nhs.uk/medicines/losartan/
  4. https://www.healthline.com/health/hydrochlorothiazide-losartan-oral-tablet#side-effects

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