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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lorthin-N Injection 10 ml is used to treat liver diseases, including hepatitis, fatty liver, jaundice, liver cirrhosis, and hepatic encephalopathy. It contains L-ornithine-L-aspartate, which facilitates the removal of ammonia by increasing glutamine and urea synthesis in the liver and glutamine synthesis in brain and muscle tissues. This medicine may cause side effects such as nausea and vomiting. Inform your doctor if you are pregnant, breastfeeding, taking any other medicines or have pre-existing medical conditions.

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Manufacturer/Marketer :

Oscar Remedies Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Lorthin-N Injection 10 ml

Lorthin-N Injection 10 ml is used to treat liver diseases such as hepatitis, fatty liver, jaundice, liver cirrhosis, and hepatic encephalopathy. It is indicated to treat different levels of mental and movement function loss (evident and latent hepatic encephalopathy) caused by liver failure.

Lorthin-N Injection 10 ml contains L-ornithine-L-aspartate that facilitates the removal of ammonia by increasing glutamine and urea synthesis in the liver and synthesis of glutamine in brain and muscle tissues.

Sometimes, Lorthin-N Injection 10 ml may cause side effects such as nausea and vomiting. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.

Inform your doctor if you are allergic to any of the components in Lorthin-N Injection 10 ml. Consult your doctor if you are pregnant or breastfeeding. Let your doctor know about your medical history and the medicines you take to rule out any side effects/interactions.

Uses of Lorthin-N Injection 10 ml

Lorthin-N Injection 10 ml is used in the treatment of liver diseases. The detailed uses of Lorthin-N Injection 10 ml are as follows:

  • Treats hepatic encephalopathy: Lorthin-N Injection 10 ml helps reduce elevated ammonia levels in the blood, improving brain function and reducing symptoms like confusion and altered consciousness caused by liver dysfunction.
  • Supports liver detoxification: Lorthin-N Injection 10 ml facilitates the conversion of ammonia into urea through the urea cycle, aiding in the detoxification process and protecting liver cells from damage.
  • Manages chronic liver disease symptoms: Lorthin-N Injection 10 ml improves metabolic function and reduces fatigue, nausea, and other symptoms associated with cirrhosis and hepatitis.
  • Corrects hyperammonemia: Lorthin-N Injection 10 ml is used to lower toxic ammonia levels in patients with impaired liver function, helping prevent complications such as coma or neurological decline.

Directions for Use

  • The timing and frequency of Lorthin-N Injection 10 ml will be determined by your doctor, based on your medical condition and response to treatment.
  • Lorthin-N Injection 10 ml will be administered by the doctor or healthcare professional.
  • Do not self-administer.

Medicinal Benefits

  • Lorthin-N Injection 10 ml enhances liver detoxification by converting toxic ammonia into non-toxic urea, aiding its elimination through urine.
  • It effectively lowers elevated blood ammonia, a common issue in liver diseases and hepatic encephalopathy.
  • Lorthin-N Injection 10 ml also treats both latent and overt hepatic encephalopathy by improving mental alertness, coordination, and psychometric performance.
  • This medicine alleviates symptoms like confusion, drowsiness, and motor dysfunction associated with liver-related brain impairment.
  • It stimulates glutamine production in the brain, liver, and muscles, which helps in neutralising and removing ammonia.
  • Lorthin-N Injection 10 ml is beneficial in conditions such as fatty liver, hepatitis, jaundice, and liver cirrhosis.
  • By reducing mental fog and improving energy levels, it enhances day-to-day functioning in liver disease patients.

How Lorthin-N Injection 10 ml Works

Lorthin-N Injection 10 ml contains L-ornithine-L-aspartate that facilitates the removal of ammonia by increasing glutamine and urea synthesis in the liver and synthesis of glutamine in brain and muscle tissues.

Storage

• Store in a cool and dry place away from sunlight.• Keep Lorthin-N Injection 10 ml out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Lorthin-N Injection 10 ml

Since Lorthin-N Injection 10 ml is given in a controlled medical setting by a healthcare professional, an overdose is not likely to occur. If you think there has been an overdose or experiencing any adverse events, get medical care right away. In a medical setting, an overdose would be treated quickly.

Drug Warnings

  • Do not take Lorthin-N Injection 10 ml if you are allergic to any of its components or have renal failure.
  • Consult your doctor if you are pregnant or breastfeeding.
  • Limited information is available regarding the usage of Lorthin-N Injection 10 ml in children; please consult your doctor if you have any concerns.
  • Let your doctor know if you are taking prescription/non-prescription medicines, supplements or herbal products.

Diet & Lifestyle Advise

  • Avoid alcohol consumption.
  • Maintain a healthy weight by exercising regularly.
  • Drink plenty of water.
  • Adopt a liver-friendly diet such as fibre-rich food.
  • Cut down on fats, sugar, and salt.
  • Quit smoking.
  • Avoid stress by practising yoga or meditation. 
  • Exercise regularly, as it helps in reducing the accumulation of fat.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS
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Alcohol

Consult your doctor

It is not known if alcohol affects Lorthin-N Injection 10 ml. Please consult your doctor.

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Pregnancy

Caution

There are no controlled studies on the use of Lorthin-N Injection 10 ml during pregnancy. Consult your doctor if you are pregnant or have any concerns; your doctor will prescribe this medicine during pregnancy only if the benefits outweigh the risks.

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Breast Feeding

Caution

The presence of this medicine in human milk is unknown. When deciding whether to stop treatment with either drug, your doctor may consider the advantages of breastfeeding for the infant and Lorthin-N Injection 10 ml treatment for the breastfeeding mother.

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Driving

Safe if prescribed

Lorthin-N Injection 10 ml is unlikely to interfere with your ability to drive. However, drive or operate machinery only if you are alert.

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Liver

Caution

Your doctor will adjust the infusion rate of Lorthin-N Injection 10 ml if your liver function is seriously compromised.

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Kidney

Caution

Please consult your doctor if you have any concerns regarding the use of Lorthin-N Injection 10 ml in patients with kidney impairment. Lorthin-N Injection 10 ml should not be used in case of severe renal impairment.

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Children

Consult your doctor

Limited information is available regarding the usage of Lorthin-N Injection 10 ml in children. Please consult your doctor.

Have a query?

FAQs

Lorthin-N Injection 10 ml is used to treat liver diseases, including hepatitis, fatty liver, jaundice, liver cirrhosis, and hepatic encephalopathy.

Lorthin-N Injection 10 ml removes ammonia by increasing glutamine and urea synthesis in the liver and synthesis of glutamine in brain and muscle tissues.

Nausea could be a side effect of Lorthin-N Injection 10 ml. It is not a common side effect in everyone who takes this medication. However, if the condition persists or worsens, consult a doctor.

Lorthin-N Injection 10 ml converts toxic, harmful ammonia into non-toxic urea, which is eliminated via the urine. It serves as a stimulus for hepatic glutamine synthesis that could be defective in acute and chronic liver disease.

Lorthin-N Injection 10 ml may be indicated to treat hepatic encephalopathy. It helps improve psychometric function in patients with hepatic encephalopathy. Hepatic encephalopathy is a liver disease in which the liver does not remove toxins from the body, leading to loss of brain function.

Lorthin-N Injection 10 ml may cause side effects such as nausea or vomiting in some people. However, if these side effects persist or worsen, please inform your doctor.

No, it is not recommended to take alcohol when taking Lorthin-N Injection 10 ml. Although, the interaction of alcohol with Lorthin-N Injection 10 ml is unknown, still alcohol should be avoided in liver failure cases as it may worsen the complication of liver disease.

Lorthin-N Injection 10 ml will be injected by a doctor or nurse. Do not self-administer.

Country of origin

India

Manufacturer/Marketer address

Oscar House, Tirath Nagar, Badi Majra, Yamunanagar 135001, Haryana (India)
Other Info - LOR1006

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