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  3. Lopsol 2mg Tablet

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Lopsol 2mg Tablet, Pack of 1 Tablet
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lopsol 2mg Tablet is used to treat diarrhoea. It is also indicated in the treatment of diarrhoea associated with inflammatory bowel disease and in reducing the volume of discharge resulting from an ileostomy (surgical opening in the abdominal wall). It contains Loperamide, which works by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Thereby, it helps treat diarrhoea. It may cause common side effects such as headache, nausea, and constipation. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Composition :

LOPERAMIDE-2MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lopsol 2mg Tablet

Lopsol 2mg Tablet is an anti-diarrhoeal medicine used to treat diarrhoea. It is also indicated in the treatment of diarrhoea associated with inflammatory bowel disease and in reducing the volume of discharge from ileostomies. Diarrhoea is a condition characterised by frequent bowel movements, resulting in loose, watery stools.

Lopsol 2mg Tablet contains Loperamide, which works by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Thereby, Lopsol 2mg Tablet helps treat diarrhoea.

The most common side effects of Lopsol 2mg Tablet are headache, nausea, and constipation. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, reach out to your doctor.

Do not take Lopsol 2mg Tablet if you are allergic to any of its components. Consult the doctor if you are pregnant or breastfeeding. Lopsol 2mg Tablet may cause dizziness; therefore, do not drive unless you are alert. Keep the doctor informed about your health conditions and medications to help rule out any potential side effects or interactions.

Uses of Lopsol 2mg Tablet

Lopsol 2mg Tablet is used in the treatment of diarrhoea. The detailed uses of Lopsol 2mg Tablet are as follows:

  • Treatment of Diarrhoea: Lopsol 2mg Tablet is effectively used to manage diarrhoea, including both acute and chronic cases.
  • Reduction of Intestinal Motility: Lopsol 2mg Tablet reduces intestinal movement, helping to alleviate gastrointestinal discomfort and related symptoms.
  • Management of Irritable Bowel Syndrome (IBS): Lopsol 2mg Tablet aids in controlling IBS symptoms, such as abdominal pain, bloating, and altered bowel habits.
  • Support During Travel: Lopsol 2mg Tablet is often taken as a preventive measure against travel-related diarrhoea, commonly referred to as traveller's diarrhoea.

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Directions for Use

  • Lopsol 2mg Tablet can be taken with or without food.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Lopsol 2mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

Medicinal Benefits

Lopsol 2mg Tablet belongs to the class of anti-diarrhoeal medication used to treat diarrhoea. It is also indicated in the treatment of diarrhoea associated with inflammatory bowel disease and for reducing the volume of discharge from ileostomies. Lopsol 2mg Tablet contains Loperamide, which works by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Thereby, Lopsol 2mg Tablet helps treat diarrhoea.

How Lopsol 2mg Tablet Works

Lopsol 2mg Tablet contains Loperamide, which works by slowing down an overactive bowel. This allows water and salts that are usually lost in diarrhoea to be absorbed by the body. Thereby, Lopsol 2mg Tablet helps treat diarrhoea.

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Lopsol 2mg Tablet
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

What if I have taken an overdose of Lopsol 2mg Tablet

Do not take more than the prescribed dose of Lopsol 2mg Tablet as it may cause an overdose. The symptoms of overdose include irregular heartbeat, increased heart rate, uncoordinated movements, muscle stiffness, drowsiness, weak breathing or difficulty urinating. If you suspect you have taken an overdose or notice signs of overdose, please consult a doctor immediately.

Drug Warnings

Do not take Lopsol 2mg Tablet if you are allergic to any of its components, if you have severe diarrhoea after taking antibiotics, ulcerative colitis, constipation, or acute dysentery (characterised by blood in the stools). Inform the doctor if you have AIDS and your stomach becomes swollen, liver or kidney disease, diarrhoea for more than 48 hours, severe diarrhoea, a history of drug abuse, slow or irregular heartbeat, low level of potassium in your blood, or prolonged QT interval (a rare heart problem). Seek immediate medical attention if you experience any of the following symptoms while taking loperamide: fast, irregular, or pounding heartbeat; dizziness; lightheadedness; unresponsiveness; or fainting. Avoid exceeding the recommended dosage, as it may lead to serious heart problems.

Drug-Drug Interactions

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LoperamidePapaverine
Severe
LoperamideRitonavir
Severe

Drug-Drug Interactions

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LoperamidePapaverine
Severe
How does the drug interact with Lopsol 2mg Tablet:
Combining Lopsol 2mg Tablet with Papaverine can raise the chance of an abnormal heart rhythm.

How to manage the interaction:
Although taking Lopsol 2mg Tablet and Papaverine together can cause an interaction, it can be taken if your doctor has suggested it. however, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations contact a doctor right away. Do not stop using any medications without consulting a doctor.
LoperamideRitonavir
Severe
How does the drug interact with Lopsol 2mg Tablet:
Taking Lopsol 2mg Tablet with ritonavir may significantly increase the blood levels of Lopsol 2mg Tablet.

How to manage the interaction:
Although taking Lopsol 2mg Tablet with ritonavir together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience abrupt dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeats while taking these medications contact a doctor immediately. Do not discontinue any medication without consulting a doctor.
LoperamideDronedarone
Severe
How does the drug interact with Lopsol 2mg Tablet:
When taken in combination dronedarone may significantly raise the Lopsol 2mg Tablet levels in the blood. This can lead to severe complications, such as abnormal heartbeat.

How to manage the interaction:
Although taking Lopsol 2mg Tablet with dronedarone together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeats while taking these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
LoperamideFosamprenavir
Severe
How does the drug interact with Lopsol 2mg Tablet:
Co-administration of Lopsol 2mg Tablet with amprenavir may raise blood levels of Lopsol 2mg Tablet, you run the risk of developing major problems including abnormal heart rhythm. Other cardiac conditions, and electrolyte imbalances, may also make you more vulnerable.

How to manage the interaction:
There may be a possibility of interaction between Lopsol 2mg Tablet and Fosamprenavir, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not discontinue any medications without consulting a doctor.
LoperamideBoceprevir
Severe
How does the drug interact with Lopsol 2mg Tablet:
Co-administration of Lopsol 2mg Tablet with boceprevir may raise blood levels of Lopsol 2mg Tablet, you run the risk of developing major problems including abnormal heart rhythm. Other cardiac conditions, and electrolyte imbalances, may also make you more vulnerable.

How to manage the interaction:
There may be a possibility of interaction between Lopsol 2mg Tablet and Boceprevir, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor. Do not stop using any medications without consulting a doctor.
LoperamideVoriconazole
Severe
How does the drug interact with Lopsol 2mg Tablet:
When Lopsol 2mg Tablet is taken in combination voriconazole may significantly raise the Lopsol 2mg Tablet levels in the blood, this can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Voriconazole and Lopsol 2mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience sudden dizziness, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not discontinue any medication without consulting a doctor.
LoperamideGemfibrozil
Severe
How does the drug interact with Lopsol 2mg Tablet:
When taken in combination Gemfibrozil may significantly raise the Lopsol 2mg Tablet levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Lopsol 2mg Tablet with Gemfibrozil together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
LoperamideItraconazole
Severe
How does the drug interact with Lopsol 2mg Tablet:
Coadministration of itraconazole with Lopsol 2mg Tablet may significantly increase the risk of abnormal heart rhythm.

How to manage the interaction:
Lopsol 2mg Tablet and itraconazole have the potential to interact, however they can still be used if a doctor prescribes them. If you suffer any of the following symptoms, seek medical attention : dizziness, lightheadedness, fainting, shortness of breath, or racing heartbeats. Never discontinue taking a drug without consulting a doctor.
LoperamideLapatinib
Severe
How does the drug interact with Lopsol 2mg Tablet:
When taken in combination lapatinib may significantly raise the Lopsol 2mg Tablet levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Lopsol 2mg Tablet with lapatinib together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
LoperamideSpironolactone
Severe
How does the drug interact with Lopsol 2mg Tablet:
When taken in combination spironolactone may significantly raise the Lopsol 2mg Tablet levels in the blood.

How to manage the interaction:
Although taking Lopsol 2mg Tablet with spironolactone together can result in an interaction, they can be taken if your doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop taking any medication without doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Drink plenty of fluids to stay hydrated.
  • Include bland foods such as bananas, rice, apples, cream of wheat, soda crackers, farina, applesauce, and toast to avoid aggravating the digestive system.
  • Avoid eating foods such as milk, dairy products, spicy foods, processed foods, pork, veal, sardines, raw vegetables, rhubarb, onions, corn, citrus fruits, alcohol, pineapples, cherries, seeded berries, grapes, caffeinated and carbonated drinks.
  • Eat fibre-rich food such as whole grains, lentils, beans, broccoli, and peas.
  • Wash your hands properly after using the toilet to prevent infections.
  • Clean the toilets regularly with a disinfectant.
  • Wash your hands thoroughly before eating, while preparing or serving.

Habit Forming

No

Therapeutic Class

ANTIDIARRHEALS

All Substitutes & Brand Comparisons

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Alcohol

Unsafe

Avoid/limit alcohol consumption as it may increase the side effects of this medicine, such as dizziness and drowsiness.

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Pregnancy

Caution

Loperamide belongs to pregnancy category C. It should be used during pregnancy only if the benefits outweigh the risks. Please consult the doctor if you are pregnant.

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Breast Feeding

Unsafe

Small amounts of Loperamide may appear in human breast milk. Therefore, it is not recommended during breastfeeding.

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Driving

Caution

Lopsol 2mg Tablet may cause dizziness, tiredness or sleepiness. Avoid driving or operating machinery if you experience these symptoms.

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Liver

Consult your doctor

No data is available in patients with liver impairment. Please consult the doctor if you have liver problems or any concerns regarding this.

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Kidney

Consult your doctor

No data is available in patients with renal impairment. Please consult the doctor if you have kidney problems or any concerns regarding this.

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Children

Caution

Lopsol 2mg Tablet is contraindicated in children below 2 years due to the risk of heart and breathing problems. Please consult the doctor if you have any concerns regarding the usage of Lopsol 2mg Tablet in children.

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Heart

Consult your doctor

Patients with cardiac conditions should exercise caution when taking Lopsol 2mg Tablet.

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Geriatrics

Caution

Lopsol 2mg Tablet should be used under caution in geriatric patients. Please consult your physician.

FAQs

Lopsol 2mg Tablet is used to treat diarrhoea. It is also indicated in the treatment of diarrhoea associated with inflammatory bowel disease and in reducing the volume of discharge from ileostomies.

Lopsol 2mg Tablet works by slowing down the movement of the bowel to decrease the number of bowel movements. It also helps lower the flow of fluids and electrolytes into the bowel.

Yes, diarrhoea may cause dehydration due to loss of fluid in stools. So, drink plenty of fluids/water to replace lost fluids due to diarrhoea. Talk to your doctor about rehydration therapy to replace lost salts.

Do not exceed the recommended dosage, as it may cause serious or life-threatening changes in your heart rhythm. Avoid taking a larger dose, taking it for a longer period of time, or taking it more often than prescribed by your doctor.

No, Lopsol 2mg Tablet is not an antibiotic. It contains loperamide, which is an anti-diarrheal medication. Loperamide works by slowing down an overactive bowel and allowing the body to absorb water and salts usually lost in diarrhoea.

Country of origin

India
Other Info - LO78183

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Author Details

Santoshini Reddy GDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Dec 3, 2025 | 7:34 AM IST

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Reference

  1. https://www.ditenate.al/en/products/pharmacy/digestive/diarrhea/loperamide-2-mg-20-tablets
  2. https://www.medicines.org.uk/emc/files/pil.12451.pdf
  3. https://medlineplus.gov/druginfo/meds/a682280.html
  4. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/017694s052lbl.pdf
  5. https://www.drugs.com/loperamide.html
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