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compositionComposition:GEMFIBROZIL-300MG
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Prescription Medicine
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Lopid Capsule is used to treat raised or increased levels of cholesterol or fat/oils. It contains Gemfibrozil, which increases the natural substance that breaks down fats in the bloodstream, thereby increasing its utilization and removal. As a result, it decreases harmful cholesterol like LDL (bad cholesterol) and triglycerides (TG) and increases levels of HDL (good cholesterol). It may cause side effects such as vomiting, abdominal pain, nausea, flatulence, and diarrhoea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

GEMFIBROZIL-300MG

Manufacturer/Marketer :

Pfizer Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lopid Capsule

Lopid Capsule is an oral prescription medication used to lower very high levels of triglycerides (fats) in the blood. By reducing these fats, it helps lower the risk of developing pancreatitis (inflammation of the pancreas) and heart disease in individuals who have not responded to diet and exercise alone. It is primarily prescribed for adults who need assistance managing their cholesterol and lipid profiles.

To get the best results, you must take Lopid Capsule consistently every day as prescribed by your doctor, usually twice a day. It works best when you take it 30 minutes before your morning and evening meals. Combining this medication with a low-fat diet, regular exercise, and weight loss can significantly improve your overall results.

While taking Lopid Capsule , some people may experience mild stomach upset, nausea, or changes in taste. However, if you experience muscle pain, tenderness, or weakness, you should contact your doctor immediately, as this can be a sign of a serious muscle condition. Always consult your doctor if you experience any persistent or severe side effects.

Before starting this medication, tell your doctor if you have a history of kidney disease, liver damage, or gallbladder problems. Do not take this medicine if you have severe kidney disease, liver damage, or gallbladder disease, as it can worsen these conditions.

This medication can interact with other drugs, especially certain cholesterol-lowering medicines and blood thinners, which can increase the risk of side effects. It is also important to talk to your doctor if you are pregnant, breastfeeding, or an older adult, as your dose or monitoring might need adjusting. Avoid drinking alcohol, as it can raise your triglyceride levels and place extra strain on your liver.

Uses of Lopid Capsule

Lopid Capsule is used to lower very high levels of triglycerides (fats). The detailed uses of Lopid Capsule are as follows:

  • Very high triglyceride levels (Hyperlipidemia): Lopid Capsule helps lower extremely high blood fat levels to prevent complications like pancreatitis.
  • Coronary heart disease risk reduction: In certain patients with high cholesterol and low 'good' (HDL) cholesterol, it helps lower the risk of heart attacks and other heart complications when other treatments have not worked.

Key Benefits

Although you may not feel any different physically while taking Lopid Capsule , its benefits are vital for your long-term health and well-being.

  • Reduces the risk of severe abdominal pain: By keeping triglyceride levels under control, this medicine helps prevent acute pancreatitis, a sudden and painful inflammation of the pancreas.
  • Protects your heart and blood vessels: By balancing your cholesterol and fat levels, it helps prevent plaque buildup in your arteries, lowering your risk of heart attacks.
  • Supports your long-term health plan: It works alongside your diet and exercise routine to help you achieve your target lipid goals, giving you peace of mind about your cardiovascular health.
Side effects of Lopid Capsule
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the steps to manage Gastrointestinal Air and Swelling (GAS) caused by medication:
  • Tell your doctor about your GAS symptoms. They may change your medication regimen or prescribe additional drugs to help you manage them.
  • To manage GAS symptoms, eat a balanced diet of fibre, vegetables, and fruits.
  • Drink enough water throughout the day to avoid constipation and treat GAS symptoms.
  • Regular exercise like yoga and walking may help stimulate digestion and alleviate GAS symptoms.
  • Take probiotics only if your doctor advises, as they may help alleviate GAS symptoms by promoting gut health.
  • Take medication for GAS symptoms only if your doctor advises, as certain medications can interact with your existing prescriptions or worsen symptoms.
  • If symptoms persist, worsen, or are accompanied by severe abdominal pain, vomiting, or bleeding, seek immediate medical attention.

Directions for Use

  • Take the medicine 30 minutes before the morning and evening meals or as advised by your doctor.
  • Recommended to take twice a day or as advised by your doctor.
  • Swallow the medicine as a whole with glass of water.
  • Do not crush, break, or chew it.

How Lopid Capsule Works

Lopid Capsule contains gemfibrozil, which belongs to a group of medications known as fibrates. It works by targeting the way your liver handles fats. Specifically, it speeds up the breakdown and removal of triglycerides from your blood, which lowers your total fat levels. Additionally, this medication reduces the amount of 'bad' cholesterol (VLDL) your liver produces while helping to boost your 'good' cholesterol (HDL). By shifting the balance of fats in your bloodstream, it helps keep your blood vessels clear and healthy.
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Alcohol

Unsafe

Alcohol may interact with Lopid Capsule . Therefore, avoid the use of alcohol while taking this Lopid Capsule .

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Pregnancy

Unsafe

It is not known whether Lopid Capsule will harm an unborn baby. Inform your doctor if you are pregnant or plan to become pregnant while using this Lopid Capsule .

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Breast Feeding

Unsafe

It is unknown whether Lopid Capsule passes into breast milk or if it could harm a nursing baby. It would be best if you did not breast-feed while taking Lopid Capsule .

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Driving

Caution

Although unlikely, you may feel dizzy or experience visual disturbances whilst taking this Lopid Capsule .

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Liver

Caution

Lopid Capsule to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Lopid Capsule to be taken with caution, especially if you have a history of kidney disease or is currently on the dialysis stage. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Lopid Capsule is not recommended for children.

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Heart

Caution

Lopid Capsule can be used in heart patients if prescribed by the physician. Please consult your physician if you have any concerns.

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Geriatrics

Caution

Lopid Capsule should be given with caution in elderly patients due to an increased risk of side effects. Seek medical advice before using Lopid Capsule .

What if I have taken an overdose of Lopid Capsule

If you take too much of this medication, seek immediate emergency medical attention right away. Symptoms of an overdose may include severe stomach cramping, muscle pain, or nausea.

Diet & Lifestyle Advise

  • Limit saturated fats and sugars: Avoid foods high in saturated fats, trans fats, and refined sugars, as these directly raise your triglyceride levels. Focus on lean proteins, whole grains, and fresh vegetables.
  • Avoid alcohol: Drinking alcohol can significantly raise your triglyceride levels and increase the risk of liver irritation while taking Lopid Capsule .
  • Incorporate healthy fats: Swap out butter and lard for healthier fats containing omega-3 fatty acids, such as olive oil, flaxseeds, and fish like salmon.
  • Exercise regularly: Aim for at least 30 minutes of moderate aerobic exercise, like brisk walking, most days of the week to help boost your 'good' cholesterol.

Health Queries

Can acute pancreatitis and diabetes be permanently cured? My medications include Glycomet 500 mg, Lopid 300, Atorva 40, Telma 40, and Cobadex Forte.

Y. Lakshmi Thulasi

Y. Lakshmi Thulasi

Pharm-D (Post baccalaureate)

With the right care, acute pancreatitis typically goes away entirely, while diabetes requires lifelong management and cannot be cured. Maintaining control over your blood sugar and cholesterol lowers the chance that pancreatitis will recur, so keep taking your medications and getting regular checkups.
health query

Have a query?

How Soon It Starts Working

The time required for Lopid Capsule to start to work: Lopid Capsule ideally shows its action within 1 to 2 hours after administration. The time for which the effects of Lopid Capsule last: The effect of Lopid Capsule lasts for 4 to 6 hours.

What if you forget to take Lopid Capsule

If you miss a dose of Lopid Capsule , take it as soon as you remember, provided it is still roughly 30 minutes before your next meal. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

•Store Lopid Capsule at controlled room temperature, ideally between 68°F and 77°F (20°C to 25°C). •Keep the medication in its original container, tightly closed, to protect it from moisture and direct light.

Drug Warnings

  • Watch for muscle pain: Check your body regularly for any unexplained muscle aches, tenderness, or weakness, especially if you also have a fever. This is a critical safety check because of the risk of serious muscle breakdown.
  • Keep up with blood tests: Attend all scheduled appointments for blood work. Your doctor will need to monitor your liver function, kidney function, and blood count regularly while you are on this medication.
  • Report sudden stomach pain: Be alert to any sudden, severe pain in your upper abdomen, as Lopid Capsule can increase the risk of developing gallstones.
  • Check your medication appearance: Always inspect your tablets or capsules before taking them to ensure they look consistent in colour and shape, and have not been damaged by moisture.

Drug-Drug Interactions

verifiedApollotooltip
  • Statins (like simvastatin or atorvastatin): Combining Lopid Capsule with statins significantly increases the risk of severe muscle damage and kidney problems.
  • Repaglinide: Taking these medications together can cause your blood sugar to drop to dangerously low levels.
  • Blood thinners (like warfarin): Lopid Capsule can increase the effects of blood thinners, which raises your risk of bleeding. Your doctor may need to adjust your blood thinner dose.
  • Colchicine: Using this combination can increase the risk of muscle pain and weakness.
GemfibrozilSelexipag
Critical
GemfibrozilRepaglinide
Critical

Drug-Drug Interactions

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GemfibrozilSelexipag
Critical
How does the drug interact with Lopid Capsule:
When Selexipag is taken with Lopid Capsule, the amount of Selexipag in the blood can go up. This can increase the risk or severity of side effects like anemia, muscle and joint pain, or electrolyte imbalance.

How to manage the interaction:
Taking Selexipag with Lopid Capsule can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle and joint pain, diarrhea, sudden dizziness, lightheadedness, fainting, shortness of breath, nausea, vomiting, flushing, and decreased appetite, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GemfibrozilRepaglinide
Critical
How does the drug interact with Lopid Capsule:
When Repaglinide is taken with Lopid Capsule, the level of Repaglinide in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Taking Repaglinide with Lopid Capsule can possibly result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
GemfibrozilLoperamide
Severe
How does the drug interact with Lopid Capsule:
When taken in combination Lopid Capsule may significantly raise the Loperamide levels in the blood. This can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
Although taking Loperamide with Lopid Capsule together can result in an interaction, they can be taken if a doctor has prescribed it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
GemfibrozilCerivastatin
Severe
How does the drug interact with Lopid Capsule:
C-administration of Lopid Capsule with Cerivastatin can develop or increase the risk of liver damage or rhabdomyolysis (the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Lopid Capsule with Cerivastatin together can possibly result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and contact your doctor right away if you notice any of these signs - liver problems, muscle damage, kidney problems, complications, pain, weakness, fever, dark urine, chills, joint pain, swelling, bruising, rash, itching, loss of appetite, tiredness, feeling sick, or bleeding. Do not discontinue any medications without consulting a doctor.
GemfibrozilAtorvastatin
Severe
How does the drug interact with Lopid Capsule:
When Lopid Capsule is taken with Atorvastatin, the chance of side effects such as liver damage and rhabdomyolysis, (an uncommon illness involving the breakdown of skeletal muscle tissue) increases.

How to manage the interaction:
Co-administration of Atorvastatin along with Lopid Capsule together can result in an interaction, it can be taken if a doctor has advised it. However, if you experience muscle pain, tenderness, or weakness especially accompanied by fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, light colored stools, and/or yellowing of the skin or eyes, you should consult the doctor. Do not stop using any medications without talking to a doctor.
GemfibrozilEluxadoline
Severe
How does the drug interact with Lopid Capsule:
When Eluxadoline is taken with Lopid Capsule, the amount of Eluxadoline in the blood can go up. This can increase the risk or severity of side effects.

How to manage the interaction:
Although taking Lopid Capsule and Eluxadoline together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms - feeling sleepy, feeling sick, throwing up, having trouble going to the bathroom, having a stomachache, or feeling very tired, it's important to call a doctor right away. Do not discontinue any medications without consulting a doctor.
GemfibrozilIrinotecan
Severe
How does the drug interact with Lopid Capsule:
Co-administration of Lopid Capsule with Irinotecan can increase the risk or severity of side effects like dehydration, lung or breathing problems, or bleeding problems.

How to manage the interaction:
Although taking Lopid Capsule and Irinotecan together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms like diarrhea, feeling weak, blood clots, lung problems, feeling sick, throwing up, stomach pain, mouth sores, shortness of breath, looking pale, feeling tired, dizziness, fatigue, fever or chills, a sore throat, muscle pain, bleeding, bruises, losing weight, pain or burning urination consult a doctor right away. Do not discontinue any medications without consulting a doctor.
GemfibrozilDicoumarol
Severe
How does the drug interact with Lopid Capsule:
Co-administration of Lopid Capsule and Dicoumarol can increase the effects of Dicumarol and cause bleeding.

How to manage the interaction:
Although there is a possible interaction between Lopid Capsule and Dicoumarol, you can take these medicines together if prescribed by a doctor. If you notice any of these symptoms - bruises, vomiting, bleeding, headache, dizziness, or weakness - make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
GemfibrozilPitavastatin
Severe
How does the drug interact with Lopid Capsule:
When Lopid Capsule is used with Pitavastatin, the chance of side effects such as liver damage and rhabdomyolysis(an uncommon but dangerous illness characterized by the breakdown of skeletal muscle tissue) increases.

How to manage the interaction:
Although there is a possible interaction between Pitavastatin and Lopid Capsule, you can take these medicines together if advised by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, tiredness, nausea, vomiting, abdominal pain, dark urine, light stools, yellowing of the skin or eyes, muscle pain, tenderness, and/or weakness, consult a doctor immediately. Do not discontinue using any medications without consulting a doctor.
GemfibrozilPravastatin
Severe
How does the drug interact with Lopid Capsule:
Taking Lopid Capsule with Pravastatin can increase the risk or severity of muscle damage or liver damage.

How to manage the interaction:
Although taking Pravastatin and Lopid Capsule together can evidently cause an interaction, it can be taken if a doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Drinking alcohol can raise your triglyceride levels, reducing the effectiveness of this medication, and may increase the strain on your liver.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[CARDIOVASCULAR AGENTS]

FAQs

Lopid Capsule is used to treat raised or increased levels of cholesterol or fat/oils.
Yes, you may use Lopid Capsule with niacin if recommended by your doctor because Lopid Capsule along with niacin can be used in patients with very high fat.
Follow the diet suggested by your doctor. Lopid Capsule will not help lower your cholesterol if you do not follow a cholesterol-lowering diet plan. Avoid drinking alcohol. It may disturb your treatment.
Usually, it is not safe to take Lopid Capsule with fusidic acid as it may lead to muscle weakness, tenderness or pain. Please consult your doctor before taking Lopid Capsule along with fusidic acid.
You should not take Lopid Capsule if you have gallbladder disease, severe liver or kidney disease. If you are also taking repaglinide or simvastatin, then you should not take Lopid Capsule .
Lopid Capsule is used with caution in patients taking warfarin, adjustments in warfarin may be required, consult your doctor before taking Lopid Capsule along with warfarin.
Lopid Capsule is a fibrate. It belongs to the group of medications called fibric acid derivatives. It is used in the treatment of high cholesterol levels.
Yes, Lopid Capsule is generally considered safe when used as directed by your doctor. However, like all medications, it can cause side effects and interact with other drugs. Common side effects are usually mild and temporary, but rare cases of more serious side effects can occur. To ensure safe use, it's essential to follow your doctor's instructions and dosage, inform your doctor about all medications, supplements, and medical conditions, and monitor your liver function and blood counts regularly. By being mindful of these factors and reporting any side effects or concerns to your doctor, you can minimize risks and enjoy the benefits of Lopid Capsule .
Lopid Capsule and fenofibrate are two different medications for treating high cholesterol and triglycerides. They belong to the same class of drugs but have distinct differences. Fenofibrate is often used first to treat high triglycerides, while gemfibrozil is reserved for patients who can't take other medications. They are not interchangeable; your doctor will determine which is best for you.
Weight loss is not a direct side effect of Lopid Capsule . However, because treatment is usually combined with a healthy diet and regular exercise, some people may lose weight as a result of these lifestyle changes. Lopid Capsule is not commonly associated with weight gain, constipation, hair loss, or erectile dysfunction, but it can cause diarrhoea in some people. If you experience sudden weight changes or any persistent or unusual symptoms, consult your doctor.
Taking Lopid Capsule with a statin is generally not recommended because it greatly increases the risk of a serious muscle condition called rhabdomyolysis. If your doctor prescribes both, they will monitor you very closely. Talk to your doctor about alternative options if you are concerned.
Taking Lopid Capsule 30 minutes before your morning and evening meals ensures that the medication is absorbed properly and works efficiently to lower your blood fats. Taking it with or after food may reduce how well your body absorbs it. Talk to your doctor or pharmacist if you have trouble with this timing.
It is highly recommended to avoid or strictly limit alcohol while taking Lopid Capsule . Alcohol can raise your triglyceride levels, directly working against the medication, and can also increase the risk of liver irritation. Talk to your doctor about safe limits for you.
If you develop unexplained muscle pain, tenderness, or weakness, especially if accompanied by a fever or dark-coloured urine, contact your healthcare provider immediately. This could be a sign of muscle breakdown, which requires prompt medical attention. Talk to your doctor right away if this occurs.
You should only take Lopid Capsule during pregnancy or while breastfeeding if your doctor decides that the benefits outweigh the potential risks to the baby. There is limited research on its safety in these situations, so it is crucial to discuss alternatives. Talk to your doctor if you are planning a pregnancy or are currently breastfeeding.
This medication does not cure high cholesterol or high triglycerides; it helps manage and control them. If you stop taking the medication, your blood fat levels are likely to rise again. To maintain the benefits, you must continue taking it as prescribed. Talk to your doctor before making any changes to your therapy.

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Country of origin

India

Manufacturer/Marketer address

The Capital, 1802, 18th Floor , Plot No. C-70, ‘G’ Block , Bandra Kurla Complex, Bandra East , Mumbai – 400051
Other Info - LOP0007
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