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compositionComposition:LORAZEPAM-2MG
prescription
Prescription Medicine
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Lopez Injection 2 ml belongs to the class of benzodiazepines. It is used in the treatment of anxiety disorder and epilepsy/fits. This medication contains lorazepam which relieves anxiety and reduces seizures by raising the gamma-aminobutyric acid (GABA), a calming chemical mediator. It also helps relax the tense muscles. Common side effects include pain, itching, swelling or redness around the injection site, drowsiness, sedation, and tiredness.

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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
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More about the Product

Composition :

LORAZEPAM-2MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lopez Injection 2 ml

Lopez Injection 2 ml is a prescription medicine injected into the body to treat serious, continuous seizures, relieve severe acute anxiety, or produce sedation before medical procedures. It belongs to a group of medicines known as benzodiazepines, which act on the brain to produce a calming effect. Because it works rapidly, it is typically used in emergency situations or hospital settings.

Since this medicine is injected by a healthcare professional, the frequency and consistency of your treatment will be decided based on your medical condition. It is not a daily, long-term medication that you take at home. To support your recovery after receiving this medicine, it is helpful to make simple lifestyle adjustments, such as getting plenty of rest, staying hydrated, and avoiding environments with excessive noise or bright lights.

While this medicine is highly effective, it can cause common side effects such as drowsiness, dizziness, and muscle weakness. You must consult your doctor immediately if you experience serious side effects, such as unusually slow or shallow breathing, extreme sleepiness, or signs of an allergic reaction.

Before receiving this medicine, tell your doctor if you have certain health conditions. Do not take this if you have severe breathing problems, sleep apnea, a muscle weakness disorder called myasthenia gravis, or narrow-angle glaucoma. It is also not suitable for individuals with severe liver damage.

This medicine can interact dangerously with alcohol, sleeping pills, and strong pain relievers, causing extreme drowsiness or slow breathing. If you are pregnant, breastfeeding, or planning a pregnancy, talk to your doctor, as this medicine may affect your baby. Elderly individuals may be more sensitive to the effects of this medication and may require lower doses and close monitoring.

Uses of Lopez Injection 2 ml

Your doctor may prescribe Lopez Injection 2 ml to help manage the following conditions:

  • Status epilepticus (severe, continuous seizures): Lopez Injection 2 ml helps stop prolonged, life-threatening seizures quickly by calming overactive electrical activity in the brain.
  • Preanesthetic sedation: It is injected before surgery or medical procedures to relieve intense anxiety, induce sleepiness, and help you forget the stress of the procedure.
  • Acute agitation or severe anxiety: It is used in emergency situations to rapidly calm patients experiencing extreme panic, agitation, or severe anxiety.

Key Benefits

When used as directed as part of your treatment plan, this medicine may provide the following benefits:

  • Rapid relief in emergencies: Because this medicine is injected directly into a vein or muscle, it starts working within minutes. This rapid onset is crucial for stopping continuous seizures quickly, which helps prevent potential brain injury.
  • Smoother medical procedures: By inducing deep relaxation and mild forgetfulness, it helps patients undergo surgical or diagnostic procedures with significantly less anxiety and physical discomfort.
  • Effective physical and mental calming: It quickly reduces the physical symptoms of severe panic or agitation, such as a racing heart and muscle tension, allowing the patient to rest and recover safely.
Side effects of Lopez Injection 2 ml
  • Burning sensation is an abnormal side effect that needs medical attention. To relieve the burning feeling, your doctor may prescribe painkillers or antidepressants.
  • Focused exercises can improve strength and reduce burning by soothing muscles.
  • Change in lifestyle and improving nutrition can reduce the causes of burning sensation and provide relief.
  • Your doctor may suggest nerve block injections as it is related to sensation in the skin.
  • Burning feeling in a specific area would need mild electrical currents to reduce pain that targets the nerve affected. This practice must be done only if your doctor mentions it.
  • Get enough sleep. Maintain a regular sleep cycle.
  • Eat a healthy diet and exercise regularly.
  • Manage stress with yoga or meditation.
  • Limit alcohol and caffeine.
  • Avoid driving or operating machinery unless you are alert.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.

Directions for Use

  • Follow your doctor's instructions on the dosage and timing of Lopez Injection 2 ml to ensure its safe and effective use.
  • Lopez Injection 2 ml will be administered by a healthcare professional in a hospital.
  • Do not self-administer this medication.

How Lopez Injection 2 ml Works

Lopez Injection 2 ml contains lorazepam, which works by enhancing the action of a natural chemical messenger in the brain called gamma-aminobutyric acid (GABA). GABA is an inhibitory neurotransmitter, which means its main job is to slow down or calm nerve activity in the central nervous system. When the medicine binds to specific receptors in the brain, it boosts GABA's calming effects. This action reduces excessive brain activity, which effectively stops seizures, relieves severe anxiety, relaxes muscles, and causes sleepiness.
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Alcohol

Unsafe

Avoid taking Lopez Injection 2 ml with alcohol as it can increase the side effects of this medicine like dizziness, drowsiness and difficulty in concentrating.

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Pregnancy

Unsafe

Lopez Injection 2 ml is considered unsafe for pregnant women. Lopez Injection 2 ml may cause harmful effects on the baby (foetus), so your doctor will weigh the benefits and potential risks before prescribing it.

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Breast Feeding

Unsafe

Lopez Injection 2 ml passes into the breast milk and may harm the baby. Avoid breastfeeding while taking Lopez Injection 2 ml.

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Driving

Unsafe

Lopez Injection 2 ml may cause sleepiness, dizziness, and drowsiness. So, it is not recommended to drive or operate machinery after taking Lopez Injection 2 ml.

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Liver

Caution

Lopez Injection 2 ml to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Lopez Injection 2 ml to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

The safety and effectiveness of Lopez Injection 2 ml in children have not been established.

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Heart

Caution

Lopez Injection 2 ml should be used with caution in patients with heart conditions, as it may increase the risk of side effects. Please inform your doctor if you have any heart problems before receiving Lopez Injection 2 ml.

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Geriatrics

Caution

Lopez Injection 2 ml should be administered with caution in elderly patients due to an increased risk of side effects. Please inform your doctor before use, as the dose may need to be adjusted if required.

What if I have taken an overdose of Lopez Injection 2 ml

Since this medicine is injected by medical professionals, an overdose is rare. However, if you suspect an overdose, seek emergency medical attention immediately. Symptoms of an overdose include extreme drowsiness, severe confusion, slurred speech, slow reflexes, shallow breathing, and loss of consciousness.

Diet & Lifestyle Advise

  • Avoid Alcohol: Avoid drinking alcohol completely after receiving this medicine, as the combination can lead to dangerous breathing difficulties, severe sleepiness, or coma.
  • Limit Stimulants: Avoid drinks containing caffeine (such as coffee, tea, and energy drinks) and nicotine, as these stimulants can counteract the calming effects of the medication.
  • Avoid Falls After Injection: Ensure you have a safe environment to rest after your injection. Avoid walking unassisted, climbing stairs, or lifting heavy objects until the sedative effects have completely worn off.
  • Create a Calm Recovery Space: Keep your recovery environment quiet and dimly lit to help ease severe anxiety or recover from a seizure episode.
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How Soon It Starts Working

The time required for Lopez Injection 2 ml to start to work: Lopez Injection 2 ml ideally shows its action within a few minutes of administration. The time for which the effects of Lopez Injection 2 ml last: Lopez Injection 2 ml effect lasts for 6 to 8 hours.

What if you forget to take Lopez Injection 2 ml

Because this medicine is typically injected by a healthcare professional in a hospital as needed, it is highly unlikely that you will miss a dose. If you are on a specific injection schedule and miss an appointment, contact your healthcare provider immediately for guidance.

Storage

•Some brands may also be stored at room temperature (up to 25°C/77°F) for a limited period, typically up to 2 weeks, before use.
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Keep Refrigerated. Do not freeze.Prepaid payment required.

Drug Warnings

  • Inspect the Vial Before Use: Always inspect the vial before injection; the liquid should be clear and colourless. Do not use if the liquid is cloudy, discoloured, or contains visible particles.
  • Avoid Driving: Do not drive, operate machinery, or perform any dangerous tasks for at least 24 to 48 hours after receiving this injection, as your coordination and judgment will be temporarily impaired.
  • Report Breathing Conditions: Ensure your medical team is fully aware of your respiratory history, especially if you have asthma, chronic obstructive pulmonary disease (COPD), or sleep apnea, before you receive this injection.
  • Do Not Stop Abruptly: If you have received this medicine frequently over a long period, do not stop treatment suddenly, as this can trigger severe withdrawal symptoms. Your doctor will help you by gradually decreasing the dose.
  • Use Sterile Needles and Syringes: Make sure the healthcare provider uses a sterile, single-use needle and syringe for the injection to prevent serious infections.

Drug-Drug Interactions

verifiedApollotooltip
  • Opioid pain medicines (like codeine, tramadol, or morphine): Combining these with Lopez Injection 2 ml can cause severe drowsiness, life-threatening breathing problems, coma, or death.
  • Other central nervous system depressants (like sleeping pills, muscle relaxants, and antihistamines): These can greatly increase drowsiness and slow down your body's reactions.
LorazepamCaptopril
Severe
LorazepamPethidine
Severe

Drug-Drug Interactions

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LorazepamCaptopril
Severe
How does the drug interact with Lopez Injection 2 ml:
Coadministration of Lopez Injection 2 ml with Captopril may show additive effects and result in low blood pressure.

How to manage the interaction:
Although taking Lopez Injection 2 ml with Captopril together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice headache, dizziness, lightheadedness, fainting, or irregular pulse or heart rate, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LorazepamPethidine
Severe
How does the drug interact with Lopez Injection 2 ml:
Using Lopez Injection 2 ml together with Pethidine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death).

How to manage the interaction:
Although there is a possible interaction between Pethidine and Lopez Injection 2 ml, you can take these medicines together if prescribed by your doctor. Your doctor can recommend other options that won't cause any problems when taken together. Do not discontinue any medications without consulting a doctor.
LorazepamKetamine
Severe
How does the drug interact with Lopez Injection 2 ml:
Using Lopez Injection 2 ml together with Ketamine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death).

How to manage the interaction:
There may be a possibility of interaction between Ketamine and Lopez Injection 2 ml, but it can be taken if prescribed by a doctor. If you feel dizzy, sleepy, confused, have trouble focusing, feel too relaxed, or have trouble breathing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
LorazepamBumetanide
Severe
How does the drug interact with Lopez Injection 2 ml:
Coadministration of Lopez Injection 2 ml with Bumetanide shows additive effects and results in low blood pressure.

How to manage the interaction:
Although taking Lopez Injection 2 ml with Bumetanide together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice headache, dizziness, lightheadedness, fainting, or irregular pulse or heart rate, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LorazepamFlumazenil
Severe
How does the drug interact with Lopez Injection 2 ml:
Co-administration of flumazenil with Lopez Injection 2 ml can increase the risk of seizures(fits).

How to manage the interaction:
Although there is a possible interaction between Flumazenil and Lopez Injection 2 ml, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without a doctor's advice.
LorazepamClozapine
Severe
How does the drug interact with Lopez Injection 2 ml:
Co-administration of Lopez Injection 2 ml with Clozapine may show additive effects and increase the risk or severity of side effects.

How to manage the interaction:
Although taking Lopez Injection 2 ml with Clozapine together can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any extreme drowsiness, confusion, shallow breathing, low blood pressure, weak pulse, and incoordination, you should contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LorazepamTramadol
Severe
How does the drug interact with Lopez Injection 2 ml:
Coadministration of Lopez Injection 2 ml with Tramadol can increase the risk and severity of side effects like dizziness, decreased breathing rate, and irregular heart rates.

How to manage the interaction:
Taking Lopez Injection 2 ml with Tramadol together is generally avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you notice any symptoms of dizziness, lightheadedness, severe headache, weakness, difficulty concentrating, or impairment in judgment, and motor coordination you should contact a doctor immediately. Avoid driving or using hazardous machines. Do not stop using any medications without talking to a doctor.
LorazepamEsketamine
Severe
How does the drug interact with Lopez Injection 2 ml:
Using Esketamine together with Lopez Injection 2 ml may increase side effects such as drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, reaction speed, and motor coordination.

How to manage the interaction:
Although taking Lopez Injection 2 ml and Esketamine together can cause an interaction, it can be taken if your doctor has suggested it. If you're having trouble with feeling sleepy, confused or finding it hard to focus, it's important to let a doctor know right away. They may have other options for you that won't cause these problems. Do not discontinue any medications without consulting a doctor.
LorazepamDezocine
Severe
How does the drug interact with Lopez Injection 2 ml:
Using Lopez Injection 2 ml together with Dezocine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness, possibly leading to coma or death).

How to manage the interaction:
Although there is a possible interaction between Lopez Injection 2 ml and Dezocine, you can take these medicines together if prescribed by your doctor. It's important to keep an eye on your health and talk to your doctor about any concerns. If you notice any symptoms like trouble breathing, pain, feeling dizzy or tired, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
LorazepamMorphine
Severe
How does the drug interact with Lopez Injection 2 ml:
Using Lopez Injection 2 ml together with Morphine can increase the risk of central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Co-administration of Morphine with Lopez Injection 2 ml can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience any symptoms like trouble breathing, feeling tired, or having a cough, dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination, make sure to contact a doctor immediately. Do not stop using any medications without consulting a doctor.

Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Avoid alcohol entirely, as it severely increases the risk of dangerous sedation and respiratory depression.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

Yes

Therapeutic Class

[SEDATIVE-HYPNOTIC DRUGS]

FAQs

Lopez Injection 2 ml belongs to a group of medications called benzodiazepines primarily used to treat epilepsy (status epilepticus) and anxiety disorder. It may be prescribed as short-term therapy for sleeping difficulties due to anxiety. It may also be used as a sedative prior to surgery.
Lopez Injection 2 ml works by increasing levels of the chemical mediator which calms brain cells (neurons), known as gamma-aminobutyric acid (GABA), this helps relieve anxiety, stops seizures attacks (fits) and relaxes the tense muscles.
Caffeine is a stimulant that may reduce the calming effects of Lopez Injection 2 ml. So, it is advisable to avoid the intake of caffeinated beverages like coffee, tea and cola or chocolate that contain caffeine.
Elderly patients are more likely to have confusion, sleepiness or age-related health issues, which may require caution and an adjustment in the dose. So, it is better to consult a doctor if you have any concerns.
There is no clinical evidence that Lopez Injection 2 ml affects fertility in either men or women. But, if you are trying to get pregnant or having problems getting pregnant while on Lopez Injection 2 ml, consult a doctor.
Lopez Injection 2 ml is a habit-forming drug. It is not likely to be addictive if you take it for 2-4 weeks. Lopez Injection 2 ml may be habit-forming if you previously had problems with drugs or alcohol. Therefore, notify your doctor if you had problems with recreational drugs or alcohol.
Do not stop taking Lopez Injection 2 ml until instructed by your doctor. Stopping Lopez Injection 2 ml suddenly may cause side effects like confusion, depression, nervousness, sweating and diarrhoea.
No. This medicine causes significant drowsiness and slows your reflexes. You must not drive, ride a bicycle, or operate machinery for at least 24 to 48 hours after your injection. Talk to your doctor to find out when it is safe to drive again.
Dizziness is a common side effect. You should lie down immediately in a safe, comfortable place to prevent falls. Do not attempt to stand or walk without help. Talk to your doctor or nurse if the dizziness does not improve.
Yes, this medicine has a temporary effect that can cause you to forget events that happen immediately after you receive the injection. This is often helpful for reducing the stress of surgical procedures. Talk to your doctor if you have questions about this effect.
The active effects of the injection usually wear off within a few hours, but traces of the medicine can remain in your system for several days. The exact time depends on your age, liver function, and overall health. Talk to your doctor or pharmacist for more specific information.

Disclaimer

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Reference

  1. National Center for Biotechnology Information (NCBI). Nbk532890 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here
  2. Drugs.com Clinical Review Team. Lorazepam Drug Interactions Reference. Auckland, NZ: Drugs.com; 2026. [Accessed on 02 Jun. 2026]Check here
  3. National Health Service (NHS). Lorazepam - NHS Medicines Reference Guide. London, UK: NHS; 2025. [Accessed on 02 Jun. 2026]Check here
  4. U.S. Food and Drug Administration (FDA). 017794S044Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  5. Lorazepam [Prescribing Information]. 2025. [Accessed on 18 Jun. 2025]Check here
  6. DailyMed - ATIVAN- lorazepam tablet [Internet]. Nih.gov. [Accessed on 2025 Nov 21]Check here
  7. Lorazepam: Worsening of delirium: 3 case reports. React Wkly [Internet]. 2017 [Accessed on 2025 Nov 21]Check here

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - LOP0015

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