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compositionComposition:LABETALOL-5MG/ML
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Lobet 20 mg Injection 4 ml is used in the treatment of increased blood pressure (hypertension). This medicine blocks the receptors in the cardiovascular system and thus helps decrease the blood pressure in the blood vessels. It is also used in the treatment of hypertension in pregnancy and during anaesthesia.

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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LABETALOL-5MG/ML

Manufacturer/Marketer :

Samarth Life Sciences Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Lobet 20 mg Injection 4 ml

Lobet 20 mg Injection 4 ml is a fast-acting injection used to treat dangerously severe high blood pressure. Its primary medical purpose is to rapidly lower blood pressure during cardiovascular emergencies, such as a hypertensive crisis. This critical treatment helps protect vital organs like your brain, heart, and kidneys from sudden damage.

Because this medicine is given as an injection into a vein, it is injected by healthcare professionals in a hospital or clinic setting rather than on a regular daily schedule at home. Since it is injected directly, food intake does not affect how it works. To support long-term results and maintain healthy blood pressure, your doctor may recommend adopting a low-sodium diet and managing stress.

Some people may experience mild side effects, such as dizziness, nausea, or a tingling sensation on the scalp. However, you must tell your medical team immediately if you face serious side effects, such as an extremely slow heart rate, chest pain, or sudden trouble breathing.

Before receiving this medicine, talk to your doctor if you have a history of heart failure, liver problems, or diabetes. Do not take this if you suffer from asthma, severe lung disease, or certain types of slow heart rate conditions.

This injection can interact with other blood pressure medicines, alcohol, and certain heart drugs, which can cause your blood pressure to drop too low. If you are pregnant, breastfeeding, or an older adult, it is highly recommended to consult your doctor or pharmacist to discuss the safety of this treatment.

Uses of Lobet 20 mg Injection 4 ml

Lobet 20 mg Injection 4 ml helps rapidly lower severely high blood pressure in emergency situations and during certain medical procedures. It may be used for: 

  • Severe high blood pressure: Lobet 20 mg Injection 4 ml helps rapidly lower dangerously high blood pressure in emergency situations to prevent immediate organ damage or stroke.
  • High blood pressure during pregnancy: It is used to safely control very high blood pressure in pregnant women experiencing pre-eclampsia.
  • Blood pressure control during surgery: It helps maintain stable blood pressure levels during and immediately after surgical procedures.

Key Benefits

Lobet 20 mg Injection 4 ml helps rapidly lower dangerously high blood pressure, protect vital organs, and support stable blood circulation. Key benefits include:

  • Rapid blood pressure control: Begins working within minutes to quickly lower severely high blood pressure in emergency situations.
  • Protects vital organs: Helps reduce the risk of complications such as stroke, heart attack, and damage to the brain, heart, and kidneys caused by uncontrolled high blood pressure.
  • Supports stable heart function: Relaxes blood vessels, allowing blood to flow more easily while helping maintain efficient heart function.
  • Provides controlled blood pressure reduction: Lowers blood pressure in a controlled manner, reducing the risk of sudden drops that may affect blood flow to vital organs.
Side effects of Lobet 20mg / 4ml Inj
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.

Directions for Use

  • Lobet 20 mg Injection 4 ml is administered by healthcare professionals through an intravenous (IV) infusion or injection.
  • The dosage and frequency are determined by your doctor, based on your blood pressure levels and overall condition.
  • Do not attempt to self-administer this injection, as improper use can lead to serious side effects like low blood pressure or heart issues.

How Lobet 20 mg Injection 4 ml Works

Lobet 20 mg Injection 4 ml contains labetalol, which works by blocking both alpha- and beta-adrenergic receptors, helping to lower blood pressure by relaxing blood vessels and reducing the workload on the heart. Labetalol blocks beta receptors, slowing the heart rate and reducing the force of each heartbeat. It also blocks alpha receptors, causing blood vessels to relax and widen. Together, these actions improve blood flow and rapidly lower blood pressure while helping maintain adequate blood supply to vital organs.
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Alcohol

Caution

It is unknown if alcohol affects the results of Lobet 20 mg Injection 4 ml. Please consult your doctor.

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Pregnancy

Caution

Lobet 20 mg Injection 4 ml belongs to pregnancy category C. Your doctor may prescribe Lobet 20 mg Injection 4 ml in case of high blood pressure during pregnancy when rapid control of blood pressure is necessary.

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Breast Feeding

Caution

Small amounts of Lobet 20 mg Injection 4 ml may pass into breastmilk. Please inform your doctor if you are breastfeeding. Your doctor will weigh the benefits and risks before prescribing this medicine.

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Driving

Caution

Lobet 20 mg Injection 4 ml may cause dizziness. Hence, do not drive vehicles or operate machines if you fell dizzy after taking Lobet 20 mg Injection 4 ml.

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Liver

Caution

Please inform your doctor if you have liver problems before receiving Lobet 20 mg Injection 4 ml. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Kidney

Caution

Please inform your doctor if you have kidney problems before receiving Lobet 20 mg Injection 4 ml. Your doctor may adjust the dose or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Lobet 20 mg Injection 4 ml is not recommended for children and adolescents below 18 years.

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Heart

Consult your doctor

Please consult your doctor before using Lobet 20 mg Injection 4 ml if you have pre-existing heart problems. Your doctor will prescribe Lobet 20 mg Injection 4 ml if the benefits outweigh the risks.

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Geriatrics

Consult your doctor

Please consult a doctor before administering Lobet 20 mg Injection 4 ml to geriatric patients. Your doctor will prescribe Lobet 20 mg Injection 4 ml if the benefits outweigh the risks.

What if I have taken an overdose of Lobet 20 mg Injection 4 ml

Since this medication is administered under strict medical supervision, an overdose is rare. However, if you suspect an overdose or experience severe dizziness, fainting, or an extremely slow heart rate, seek immediate medical attention. Hospital staff will treat these symptoms right away.

Diet & Lifestyle Advise

  • Limit sodium intake: Eat a low-salt diet to help maintain healthy blood pressure levels after your emergency treatment.
  • Avoid alcohol: Do not drink alcohol, as it can interact with this medicine to cause a sudden, dangerous drop in blood pressure.
  • Change positions slowly: Sit up or stand up very gradually from a lying position to prevent dizziness and falls.
  • Follow a heart-healthy diet: Incorporate plenty of fruits, vegetables, whole grains, and lean proteins into your meals to support long-term heart health.
health query

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How Soon It Starts Working

The time required for Lobet 20 mg Injection 4 ml to start to work: Lobet 20 mg Injection 4 ml ideally shows its action within 2 to 5 minutes after administration. The time for which the effects of Lobet 20 mg Injection 4 ml last: The effect of Lobet 20 mg Injection 4 ml lasts for 4 hours.

What if you forget to take Lobet 20 mg Injection 4 ml

Because this medicine is injected by a healthcare professional in a hospital or clinic, it is highly unlikely that you will miss a dose. If you have concerns about your treatment schedule, talk to your doctor or pharmacist.

Storage

•Store Lobet 20 mg Injection 4 ml at controlled room temperature (20°C to 25°C) in its original carton to protect it from light. •Do not freeze the injection.

Drug Warnings

  • Inspect the solution: Ensure the injection is clear, colourless to pale yellow, and free from visible particles before administration. Do not use it if it appears cloudy or discoloured.
  • Remain lying down: Do not stand up or walk for at least 3 hours after receiving the injection unless your healthcare provider advises otherwise, as it may cause dizziness or fainting.
  • Share your medical history: Tell your healthcare team if you have asthma, chronic bronchitis, emphysema, or other breathing problems before receiving this medicine.
  • Monitor vital signs: Your blood pressure and heart rate should be closely monitored during and after treatment.
  • Report unusual symptoms: Tell your doctor immediately if you experience cold hands or feet, unusual tiredness or weakness, difficulty breathing, or worsening dizziness.

Drug-Drug Interactions

verifiedApollotooltip
  • Other blood pressure lowering drugs: May cause an excessive, sudden drop in blood pressure when combined.
  • Calcium channel blockers (such as diltiazem or verapamil): May lead to a dangerously slow heart rate or heart block.
  • Diabetes medications: May hide the symptoms of low blood sugar, such as an increased heart rate.
LabetalolLomitapide
Severe
LabetalolClonidine
Severe

Drug-Drug Interactions

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LabetalolLomitapide
Severe
How does the drug interact with Lobet 20mg / 4ml Inj:
Taking Lobet 20mg / 4ml Inj with Lomitapide can increase the risk of liver damage.

How to manage the interaction:
Co-administration of Lobet 20mg / 4ml Inj with Lomitapide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience symptoms such as fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, exhaustion, nausea, vomiting, dark urine, light stools, and skin or eye yellowing, decreased hunger, consult the doctor. Do not stop using any medications without talking to the doctor.
LabetalolClonidine
Severe
How does the drug interact with Lobet 20mg / 4ml Inj:
Co-administration of Clonidine and Lobet 20mg / 4ml Inj may increase the risk of side effects like lower blood pressure and slower heart rate.

How to manage the interaction:
Although there is a possible interaction between Clonidine and Lobet 20mg / 4ml Inj, you can take these medicines together if prescribed by a doctor. However, if you experience headaches, slow heartbeat, dizziness, contact a doctor. Do not discontinue the medication without consulting a doctor.
LabetalolMethyldopa
Severe
How does the drug interact with Lobet 20mg / 4ml Inj:
Co-administration of Methyldopa with Lobet 20mg / 4ml Inj, the effectiveness of Methyldopa might be reduced.

How to manage the interaction:
Although taking Lobet 20mg / 4ml Inj and Methyldopa together can result in an interaction, it can be taken if a doctor has prescribed it. Do not discontinue any medications without a doctor's advice.
LabetalolFormoterol
Severe
How does the drug interact with Lobet 20mg / 4ml Inj:
Co-administration of Lobet 20mg / 4ml Inj and formoterol together could decrease the effects of both medications.

How to manage the interaction:
Although taking Lobet 20mg / 4ml Inj and Formoterol together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
LabetalolLevosalbutamol
Severe
How does the drug interact with Lobet 20mg / 4ml Inj:
When Levosalbutamol is used in combination with Lobet 20mg / 4ml Inj, the therapeutic effectiveness of Levosalbutamol can be decreased which may lead to low treatment outcomes.

How to manage the interaction:
Taking Levosalbutamol with Lobet 20mg / 4ml Inj may lead to an interaction, but can be taken if prescribed by the doctor. However, if you experience any unusual symptoms, consult the doctor. Do not discontinue any medications without consulting a doctor.
LabetalolFingolimod
Severe
How does the drug interact with Lobet 20mg / 4ml Inj:
Taking Lobet 20mg / 4ml Inj with Fingolimod can increase the chance of a serious abnormal heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between Lobet 20mg / 4ml Inj and Fingolimod, but it can be taken if prescribed by a doctor. However, if you experience sudden dizziness, breathing difficulty, chest pain or rapid heartbeat, consult the doctor immediately. Do not stop any medications without a doctor's advice.
LabetalolPirbuterol
Severe
How does the drug interact with Lobet 20mg / 4ml Inj:
Taking Lobet 20mg / 4ml Inj with Pirbuterol may reduce the action of both the medications. Lobet 20mg / 4ml Inj can sometimes cause narrowing of the airways, which may worsen your breathing problems or trigger severe asthmatic attacks.

How to manage the interaction:
Although there is a possible interaction between Pirbuterol and Lobet 20mg / 4ml Inj, you can take these medicines together if prescribed by your doctor. However, If you notice any symptoms like asthma, breathing problems, consult the doctor right away. Do not stop using any medications without talking to a doctor.
LabetalolAminophylline
Severe
How does the drug interact with Lobet 20mg / 4ml Inj:
Combination of Aminophylline with Lobet 20mg / 4ml Inj can make Lobet 20mg / 4ml Inj less effective and increase the side effects of aminophylline which can be serious.

How to manage the interaction:
Although taking Lobet 20mg / 4ml Inj and Aminophylline together can result in an interaction, it can be taken only if a doctor has advised it. However, if you experience irregular heartbeats, or difficulty in breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
LabetalolAtazanavir
Severe
How does the drug interact with Lobet 20mg / 4ml Inj:
Taking Atazanavir and Lobet 20mg / 4ml Inj can raise the risk of a possibly serious heart rhythm irregularity.

How to manage the interaction:
Although taking Lobet 20mg / 4ml Inj and Atazanavir together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden lightheadedness, an irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.
LabetalolSaquinavir
Severe
How does the drug interact with Lobet 20mg / 4ml Inj:
Co-administration of Lobet 20mg / 4ml Inj along with Saquinavir can increase the risk of irregular heart rhythms.

How to manage the interaction:
Although taking Lobet 20mg / 4ml Inj and Saquinavir together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience sudden lightheadedness, dizziness, fainting, a slow pulse, or an irregular heartbeat, consult a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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Alcohol: May increase the risk of extreme dizziness, fainting, or a sudden blood pressure drop.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Lobet 20 mg Injection 4 ml is an anti-hypertensive medicine used in the treatment of severe hypertension. It is also used to control high blood pressure in pregnancy and during anaesthesia.
Lobet 20 mg Injection 4 ml works by blocking the receptors in the cardiovascular system, this helps in decreasing the blood pressure in the blood vessels. Thereby, helping in lowering the blood pressure to normal.
Lobet 20 mg Injection 4 ml may cause erectile dysfunction (impotence). Please consult your doctor if you have any concerns regarding these.
Lobet 20 mg Injection 4 ml might mask the effects of sudden blood loss and might affect pupils during cataract surgery, so inform the surgeon ahead of time that you are on treatment with Lobet 20 mg Injection 4 ml if you are due to have surgery.
No, this injection is designed to be given only by a trained healthcare professional in a hospital or clinic setting where your blood pressure and heart rate can be monitored closely. Talk to your doctor for more information.
Lobet 20 mg Injection 4 ml can cause postural hypotension, a sudden drop in blood pressure when standing, leading to dizziness or fainting. You should lie flat for at least 3 hours after receiving the injection and stand up slowly when advised. Inform your healthcare provider if you continue to feel dizzy or lightheaded.
No, this medicine can cause your airways to narrow, which can make breathing very difficult if you have asthma or severe lung disease. Always tell your healthcare provider about your complete medical history. Talk to your doctor for alternative options.
Lobet 20 mg Injection 4 ml is commonly used to treat severe high blood pressure during pregnancy when blood pressure needs to be lowered rapidly. It should only be given under the supervision of a specialist who will carefully monitor both the mother and baby. Your doctor will weigh the benefits and risks before treatment.
Because this medicine is given in a hospital, healthcare professionals will monitor your heart rate constantly. If it drops too low, they will adjust the treatment immediately. Talk to your doctor if you feel unusually tired or dizzy.
You should avoid alcohol after receiving this injection, as alcohol can interact with the medicine to cause severe dizziness, lightheadedness, or a sudden drop in blood pressure. Talk to your doctor or pharmacist.
This injection is used to rapidly control dangerously high blood pressure in emergency situations, but it does not cure high blood pressure. You will likely need long-term oral medications and lifestyle changes to keep your blood pressure stable. Talk to your doctor.

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Country of origin

India

Manufacturer/Marketer address

Samarth House, 168, Bangur Nagar, Off Link Road, Near Ayappa Temple & Kallol Kali Temple, Goregaon (W), Mumbai - 400 090.
Other Info - LOB0015
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