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compositionComposition:HYDROCHLOROTHIAZIDE-12.5MG+LISINOPRIL-5MG
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Prescription Medicine
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Lispro H 5mg/12.5mg Tablet is used to treat high blood pressure. It contains Lisinopril and Hydrochlorothiazide which work by relaxing and widening the narrowed blood vessels and removing extra water/fluid and certain electrolyte overload from the body. In some cases, this medicine may cause side effects such as nausea, taste change, stomach pain, diarrhoea, dizziness, decreased blood pressure, and cough. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Written By Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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More about the Product

Composition :

HYDROCHLOROTHIAZIDE-12.5MG+LISINOPRIL-5MG

Manufacturer/Marketer :

Johnlee Pharmaceuticals Pvt Ltd

Consume Type :

Oral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Lispro H 5mg/12.5mg Tablet

Lispro H 5mg/12.5mg Tablet is a prescription medication used to treat high blood pressure (hypertension). By lowering elevated blood pressure, it helps reduce the risk of serious cardiovascular events such as strokes and heart attacks. This combination treatment is typically prescribed when a single medication is not enough to control your blood pressure.

For the best results, you must take Lispro H 5mg/12.5mg Tablet consistently at the same time every day, either with or without food. Maintaining a regular routine helps keep a steady level of the medication in your body. Along with taking your medicine daily, adopting a low-sodium diet and engaging in regular, moderate exercise will significantly support your blood pressure goals.

While taking Lispro H 5mg/12.5mg Tablet, some people may experience mild side effects like dizziness, lightheadedness, or a dry cough. However, if you notice signs of a serious allergic reaction, such as swelling of your face, lips, tongue, or throat, you must seek emergency medical care immediately. Always consult your doctor if any side effect becomes persistent or bothersome.

Do not take this if you are pregnant, as it can cause serious harm or death to an unborn baby. You should also avoid this medication if you have a history of severe allergic swelling (angioedema) or are unable to urinate. Before starting Lispro H 5mg/12.5mg Tablet, talk to your doctor if you have kidney disease, liver damage, diabetes, or gout.

This medicine can interact with other treatments, such as certain pain relievers, potassium supplements, or alcohol, which may increase the risk of kidney strain or dangerously low blood pressure. Pregnant, breastfeeding, or elderly individuals should consult their healthcare provider to discuss the specific risks and benefits. Talk to your doctor for personalised guidance.

Uses of Lispro H 5mg/12.5mg Tablet

Lispro H 5mg/12.5mg Tablet may be prescribed by your doctor for: 

  • High blood pressure (hypertension): Lispro H 5mg/12.5mg Tablet helps lower elevated blood pressure, making it easier for your heart to pump blood throughout your body.

Key Benefits

Lispro H 5mg/12.5mg Tablet offers effective, dual-action control for individuals struggling to manage their hypertension. By targeting high blood pressure through two distinct mechanisms, it provides reliable protection for your heart, brain, and kidneys.

  • Reduces cardiovascular risk: Lowering high blood pressure directly decreases your chances of suffering a stroke or heart attack.
  • Simplified daily routine: Combining two blood pressure-lowering therapies into one daily tablet reduces the number of pills you need to take.
  • Long-term organ protection: Sustained blood pressure control helps prevent strain on delicate blood vessels in your kidneys and eyes.
Side effects of Lispro H 5mg/12.5mg Tablet
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Change positions or take a break from activity to relieve symptoms.
  • Avoid postures that put a lot of pressure on just one area of the body.
  • If you have vitamin deficiency, take supplements or change your diet.
  • Exercise regularly like cycling, walking or swimming.
  • Avoid sitting with your legs crossed.
  • Clench and unclench your fists and wiggle your toes.
  • Massage the affected area.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Here are the steps to manage the medication-triggered Upper respiratory tract infection:
  • Inform your doctor about the symptoms you're experiencing due to medication.
  • Your doctor may adjust your treatment plan, which could include changing your medication, adding new medications, or offering advice on managing your symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids to help loosen and clear mucus from your nose, throat, and airways.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your symptoms don't subside or worsen, consult your doctor for further guidance.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.

Directions for Use

  • Lispro H 5mg/12.5mg Tablet can be taken with or without food as advised by your doctor.
  • Lispro H 5mg/12.5mg Tablet is usually taken once a day, or as prescribed by your doctor.
  • Swallow Lispro H 5mg/12.5mg Tablet as a whole with a glass of water.
  • Do not crush, break, or chew it.

How Lispro H 5mg/12.5mg Tablet Works

Lispro H 5mg/12.5mg Tablet contains two active components, lisinopril and hydrochlorothiazide, which work together to lower your blood pressure more effectively than either component could alone. The first component, lisinopril, is an ACE inhibitor. It works by blocking a natural substance in the body that causes blood vessels to tighten and narrow. By preventing this action, the medicine relaxes and widens your blood vessels, allowing blood to flow more smoothly and with less resistance. The second component, hydrochlorothiazide, is a thiazide diuretic, commonly known as a water pill. It prompts your kidneys to remove excess water and salt from your body through your urine. This reduces the overall volume of fluid circulating in your bloodstream, which decreases the pressure on your arterial walls. Together, these two mechanisms provide comprehensive blood pressure control.
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Alcohol

Unsafe

It is advised to avoid consuming alcohol with Lispro H 5mg/12.5mg Tablet as it could lead to increased drowsiness or dizziness.

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Pregnancy

Unsafe

The use of Lispro H 5mg/12.5mg Tablet or any ACE inhibitors (lisinopril) is usually contraindicated during the second and third trimester of pregnancy. It may cause harm to the developing fetus. Hence, you should always consult your doctor before using Lispro H 5mg/12.5mg Tablet.

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Breast Feeding

Unsafe

Use of Lispro H 5mg/12.5mg Tablet is not recommended during breastfeeding.

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Driving

Unsafe

Drive with caution, Lispro H 5mg/12.5mg Tablet may cause blurry vision, and dizziness or weariness may occur.

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Liver

Caution

Lispro H 5mg/12.5mg Tablet to be taken with caution, especially in case of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Lispro H 5mg/12.5mg Tablet to be taken with caution, especially in case of severe kidney disease. The dose may have to be adjusted by your doctor.

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Children

Caution

Lispro H 5mg/12.5mg Tablet is not recommended for children aged below 6 years. Also, Lispro H 5mg/12.5mg Tablet is not recommended for children with severe kidney impairment.

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Heart

Safe if prescribed

Lispro H 5mg/12.5mg Tablet is safe for use in heart patients if recommended by the physician.

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Geriatrics

Caution

Lispro H 5mg/12.5mg Tablet should be used under caution in geriatric patients. Please consult your physician.

What if I have taken an overdose of Lispro H 5mg/12.5mg Tablet

In case of an accidental overdose, seek emergency medical attention or contact a poison control centre immediately. Symptoms of an overdose may include severe dizziness, fainting, or a rapid or unusually slow heart rate.

Diet & Lifestyle Advise

  • Limit sodium intake: Restricting the amount of salt in your diet directly supports the action of this medication and helps lower blood pressure.
  • Stay consistently hydrated: Because this medication contains a mild diuretic, drink adequate water daily, but consult your doctor about the right fluid intake for your specific health profile.
  • Avoid potassium-rich salt substitutes: Do not use salt substitutes containing potassium without consulting your doctor, as this medication can cause your body to retain potassium.
  • Rise slowly: To prevent dizziness or fainting, take your time when moving from a sitting or lying position to a standing position.
     
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How Soon It Starts Working

The time required for Lispro H 5mg/12.5mg Tablet to start to work: Lispro H 5mg/12.5mg Tablet starts to show its action within 1 hour of administration. The time for which the effects of Lispro H 5mg/12.5mg Tablet last: Lispro H 5mg/12.5mg Tablet effect lasts for 24 hours.

What if you forget to take Lispro H 5mg/12.5mg Tablet

If you miss a dose of Lispro H 5mg/12.5mg Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one. Talk to your doctor if you frequently miss doses.

Storage

•Store Lispro H 5mg/12.5mg Tablet tablets at room temperature, ideally between 20°C and 25°C (68°F to 77°F). •Keep the medication in its original container, tightly closed, to protect it from moisture and direct light. Do not store this medicine in damp areas.

Drug Warnings

  • Monitor Your Blood Pressure: Check your blood pressure regularly at home and keep a record to share with your healthcare provider during follow-up visits.
  • Attend Regular Check-Ups: Keep all scheduled appointments so your doctor can monitor your kidney function and electrolyte levels through routine blood tests.
  • Avoid Alcohol: Alcohol may increase dizziness, lightheadedness, and the risk of excessively low blood pressure while taking this medicine.
  • Avoid Use During Pregnancy: Stop taking Lispro H 5mg/12.5mg Tablet and contact your doctor immediately if you become pregnant or suspect that you may be pregnant, as lisinopril can harm the unborn baby.
  • Protect Your Skin from Sunlight: Hydrochlorothiazide may increase sensitivity to sunlight. Use sunscreen, wear protective clothing, and limit prolonged sun exposure while outdoors.

Drug-Drug Interactions

verifiedApollotooltip

The following medicines may interact with Lispro H 5mg/12.5mg Tablet and require caution, closer monitoring, or advice from your doctor:

  • Potassium supplements or potassium-sparing water pills: Combining these with Lispro H 5mg/12.5mg Tablet can lead to dangerously high levels of potassium in your blood.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen: Regular use of these pain relievers can reduce the blood pressure-lowering effect of Lispro H 5mg/12.5mg Tablet and increase the risk of kidney strain.
  • Lithium: This medication can decrease the clearance of lithium from your body, significantly increasing the risk of lithium toxicity.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

Certain foods and drinks may affect blood pressure, potassium levels, or the tolerability of Lispro H 5mg/12.5mg Tablet. Important interactions include:

  • Alcohol: Drinking alcohol can increase the blood pressure-lowering effect of Lispro H 5mg/12.5mg Tablet, leading to severe dizziness or fainting.
  • Salt substitutes: Many salt substitutes contain potassium instead of sodium, which can elevate your blood potassium levels to unsafe levels.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTI- HYPERTENSIVES]

FAQs

Lispro H 5mg/12.5mg Tablet is used to treat high blood pressure. Thus, it reduces the chances of heart attack or stroke.
Lispro H 5mg/12.5mg Tablet contains Lisinopril and hydrochlorothiazide. Lisinopril belongs to the group of medicines called Angiotensin Converting Enzyme (ACE) Inhibitors that work by lowering the body’s production of substances that could increase blood pressure. Hydrochlorothiazide (diuretic) works by increasing the amount of urine passed out from the kidneys. Thus, collectively, both help lower high blood pressure, reducing the chances of heart attack or stroke.
Usually, Lispro H 5mg/12.5mg Tablet is prescribed for a long term treatment ranging from weeks to months or for life long also for treating lowering raised blood pressure, swelling due to fluid overload (oedema) and heart-related conditions. However, taking it on your own for years without a doctor's consent can be fatal. Hence, only take it as long as your doctor has prescribed it to you.
Yes, Lispro H 5mg/12.5mg Tablet can cause dizziness. It is advised to avoid driving or operate any heavy machinery while taking Lispro H 5mg/12.5mg Tablet. In case you feel dizzy or lightheaded, it is advised to rest for some time until you feel better.
No. Do not stop taking Lispro H 5mg/12.5mg Tablet just because your blood pressure is normal. The medicine controls your blood pressure but does not cure hypertension. Stopping it without your doctor's advice may cause your blood pressure to rise again and increase the risk of serious complications such as heart attack or stroke. Always consult your doctor before stopping or changing your treatment.
If you forget to take Lispro H 5mg/12.5mg Tablet at any time, take it as soon as you remember, then continue to take it at the usual times. Do not take a double dose to make up for a forgotten dose.
No, it is a prescribed drug given by a physician for preventing specific medical conditions. Taking it on your own can cause unwanted side-effects.
The common side effects of Lispro H 5mg/12.5mg Tablet are nausea, taste change, stomach pain, diarrhoea, dizziness, decreased blood pressure, cough, increased blood lipid level, and electrolyte imbalance. Most of these resolve over time and do not require medical attention. Please consult your doctor if any of these side effects persist or worsen.
Lispro H 5mg/12.5mg Tablet is a combination medication used to treat hypertension (high blood pressure). It works by relaxing blood vessels, improving blood flow, and thinning the blood by removing excess fluids through urination. Doing so reduces the workload on the heart, enabling it to pump blood more efficiently and with less pressure.
The optimal time to take Lispro H 5mg/12.5mg Tablet is typically in the morning, as it helps to maintain blood pressure control throughout the day. However, it is essential to follow your doctor's specific instructions regarding the best time to take your medication.
When taking Lispro H 5mg/12.5mg Tablet, exercising caution and monitoring your health is crucial. Inform your doctor about any pre-existing kidney or liver disease, diabetes, or heart conditions to ensure safe treatment. Regularly check your blood pressure and kidney function, and be aware of signs of low blood pressure, such as dizziness or fainting. Additionally, report any unusual symptoms, like swelling or difficulty breathing, and limit your intake of salt, potassium-rich foods, and certain medications. By being proactive and following these guidelines, you can minimize potential risks and maximize the benefits of your treatment.
Avoid consumption of alcohol while taking Lispro H 5mg/12.5mg Tablet. Alcohol can increase the risk of side effects such as dizziness, low blood pressure, and heartburn. Additionally, combining alcohol with this medication may reduce its effectiveness in controlling your blood pressure.
Taking more than the required dose of Lispro H 5mg/12.5mg Tablet leads to an overdose. Symptoms of overdose include low blood pressure, fast or slow heartbeat, palpitations, shock, rapid breathing, cough, nausea, vomiting, dizziness, feeling sleepy and confused or anxious, excessive urination, or not being able to urinate. If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention, even if there are no symptoms.
Take Lispro H 5mg/12.5mg Tablet as your doctor prescribes; your doctor will evaluate your health condition and suggest whether you can take Lispro H 5mg/12.5mg Tablet every day. Therefore, follow your doctor's instructions regarding the dosage and frequency.
Lispro H 5mg/12.5mg Tablet may alter the blood sugar levels in your body. Therefore, it is necessary to inform your doctor if you have diabetes before taking Lispro H 5mg/12.5mg Tablet. Your doctor will closely monitor your blood sugar levels to avoid the risk of side effects.
This is a common side effect of the ACE inhibitor component of the medication, which can cause a buildup of a natural chemical called bradykinin in the airways. If the cough becomes persistent or bothersome, talk to your doctor, who may suggest an alternative medication.
You should avoid alcohol, potassium supplements, and salt substitutes containing potassium. Additionally, limit your exposure to direct sunlight and avoid taking over-the-counter NSAID pain relievers without consulting your doctor.
You should avoid taking ibuprofen or other NSAIDs regularly without consulting your doctor. These pain relievers can reduce the effectiveness of Lispro H 5mg/12.5mg Tablet and significantly increase the risk of kidney strain. Talk to your doctor about safer pain-relief alternatives.
Dizziness is common, especially when first starting the medication or when standing up. To manage this, rise slowly from sitting or lying down. If the dizziness is severe, causes fainting, or does not improve over time, talk to your doctor immediately.

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Manufacturer/Marketer address

Opp. Naveen Anaj Mandi, Sarverkhera Kashipur, Udham Singh Nagar Uttarakhand
Other Info - LI85250
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