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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lipicure-CV 40 Capsule is used to prevent heart attack and stroke in the future. It lowers the raised level of cholesterol and fats (triglycerides) in our bodies. It contains Atorvastatin and Clopidogrel, which lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Also, it prevents a clot in the blood vessels. In some cases, it may cause side effects such as headaches, ankle swelling (oedema), slow heart rate, and nausea. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.

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Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lipicure-CV 40 Capsule

Lipicure-CV 40 Capsule is used in the prevention of heart attack, myocardial infarction (blockage of the blood to muscles of the heart), angina (chest pain), and stroke. A heart attack occurs when your coronary arteries (blood vessels supplying blood and oxygen to the heart) become blocked due to the buildup of fats (plaque), including cholesterol.

Lipicure-CV 40 Capsule is a combination of Atorvastatin and Clopidogrel. Atorvastatin blocks the ability of the body to produce bad cholesterol and improves the ability of the body to make good cholesterol. Clopidogrel works by decreasing the production of clots, which is harmful to the body.

Not everyone who is taking Lipicure-CV 40 Capsule will get these side effects. You may sometimes experience headaches, ankle swelling (oedema), slow heart rate, dizziness, and nausea. Most of these side effects of Lipicure-CV 40 Capsule do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your physician if you are allergic to Lipicure-CV 40 Capsule . Before starting the dose of Lipicure-CV 40 Capsule , let your doctor know if you are sensitive to atorvastatin or clopidogrel or have any active liver disease (liver enzyme abnormalities), active bleeding issues (like peptic ulcer, brain haemorrhage), or muscle problems (myopathy or rhabdomyolysis), or if you are pregnant/breastfeeding. 

Uses of Lipicure-CV 40 Capsule

Lipicure-CV 40 Capsule is used in the treatment of hyperlipidemia (increased cholesterol) and the prevention of cardiovascular events. The detailed uses of Lipicure-CV 40 Capsule are as follows:

  • Treatment of Hyperlipidemia: Lipicure-CV 40 Capsule is used to treat hyperlipidemia by lowering cholesterol levels, particularly LDL (bad) cholesterol.
  • Prevention of Heart Attacks: Lipicure-CV 40 Capsule helps to prevent heart attacks by inhibiting platelet aggregation, reducing the risk of blood clots.
  • Stroke Prevention: Lipicure-CV 40 Capsule helps prevent strokes by reducing platelet aggregation, thereby decreasing the risk of clot formation in blood vessels.

Directions for Use

• Lipicure-CV 40 Capsule can be taken with or without food as advised by your doctor. • Follow your doctor's instructions on the dosage and timing of this medication to ensure safety. • Swallow Lipicure-CV 40 Capsule as a whole with a glass of water. • Do not chew, crush or break it.

Medicinal Benefits

  • Atorvastatin is a lipid-lowering medication that blocks the enzyme required to make cholesterol in the body.
  • Lipicure-CV 40 Capsule helps lower the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL).
  • Clopidogrel is a blood thinner (anticoagulant) that collectively prevents clot formation in the blood vessels.
  • It reduces the risk of heart attack, stroke and heart-related chest pain (angina).

How Lipicure-CV 40 Capsule Works

Lipicure-CV 40 Capsule is composed of two medicines, namely: Atorvastatin and Clopidogrel. Atorvastatin is a lipid-lowering medication which blocks the enzyme required to make cholesterol in the body. As a result, it lowers the bad cholesterol (low-density lipoproteins or LDL) and triglycerides (TG) and increases the levels of good cholesterol (high-density lipoproteins or HDL). Clopidogrel is a blood thinner (anticoagulant) that collectively prevents a clot in the blood vessels. Together Lipicure-CV 40 Capsule reduces the increased levels of bad cholesterol (low-density lipoprotein and triglycerides) and prevents blood clots, thereby reducing the risk of heart attack, stroke and heart-related chest pain (angina).

Storage

• Store in a cool and dry place away from sunlight. • Keep out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Lipicure-CV 40 Capsule

Do not take more than the prescribed dose of Lipicure-CV 40 Capsule as it may cause vomiting, breathing difficulty, gastrointestinal haemorrhage, and extreme physical weakness. If you suspect you have taken an overdose, please consult a doctor immediately.

Drug Warnings

  • Tell your doctor if you are sensitive to Atorvastatin or clopidogrel, have any active liver disease, active bleeding issues (like peptic ulcer, brain haemorrhage), are pregnant or planning to become pregnant or are breastfeeding.
  • The patient should inform the doctor that they are taking Lipicure-CV 40 Capsule before any surgery is scheduled or any new medicine is taken.
  • Atorvastatin present in Lipicure-CV 40 Capsule is a pregnancy category X drug, so it is contraindicated in pregnant women. It may cause harm to the foetus if administered to pregnant women.
  • The risk of muscle disease might increase if Lipicure-CV 40 Capsule is taken with an antibiotic (clarithromycin), anti-HIV drugs (ritonavir, lopinavir, darunavir, atazanavir, indinavir) and antifungal (itraconazole).
  • Coadministration with anticoagulants like warfarin may cause gastric bleeding and other bleeding problems. So, if you are using any blood-thinning agents, let your doctor know.
  • Lipicure-CV 40 Capsule contains atorvastatin, which can cause muscle problems like myopathy and rhabdomyolysis.
  • Patients with active liver disease should use the Lipicure-CV 40 Capsule with caution.
  • The safety and effectiveness of Lipicure-CV 40 Capsule have not been established, so its use should be avoided in paediatric patients or children younger than ten years of age.
  • Discontinuation of Lipicure-CV 40 Capsule may lead to cardiovascular events like heart attack, stroke and angina (heart-related chest pain). Hence, you should consult a doctor before stopping the dose of Lipicure-CV 40 Capsule .

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Lipicure-CV 40 Capsule:
When Selexipag and Lipicure-CV 40 Capsule are taken together, the body's ability to break down Selexipag may be reduced.

How to manage the interaction:
Taking Lipicure-CV 40 Capsule with Selexipag is not recommended, please consult your doctor before taking it. They can be taken if prescribed by your doctor.
How does the drug interact with Lipicure-CV 40 Capsule:
Taking Lipicure-CV 40 Capsule together with mifepristone increases the risk of vaginal bleeding in women.

How to manage the interaction:
Although taking Lipicure-CV 40 Capsule with mifepristone is not recommended, that would certainly result in interaction, it can be taken if a doctor prescribes it. If you experience prolonged and heavy bleeding, consult a doctor immediately. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Lipicure-CV 40 Capsule:
Taking Lipicure-CV 40 Capsule with Posaconazole can increase the blood levels of Lipicure-CV 40 Capsule. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Lipicure-CV 40 Capsule, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lipicure-CV 40 Capsule:
Taking Lipicure-CV 40 Capsule with acalabrutinib may increase the risk of bleeding.

How to manage the interaction:
There could be a possible interaction between Lipicure-CV 40 Capsule and Acalabrutinib, but they can be taken together if your doctor has prescribed them. However, consult your doctor immediately if you experience any unusual bleeding or have other signs of bleeding, like feeling dizzy or lightheaded, red or black, sticky stools, or severe headaches. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Lipicure-CV 40 Capsule:
Lipicure-CV 40 Capsule increases the blood levels of Repaglinide, which results in increased effectiveness of Repaglinide. When these medicines are taken together, you may experience low blood sugar (hypoglycemia).

How to manage the interaction:
Although taking Lipicure-CV 40 Capsule with Repaglinide may result in interaction, it can be taken if prescribed by a doctor. However, if you experience any signs of hypoglycemia (low blood sugar), consult your doctor immediately. Common symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, weakness, tremor, nausea, hunger, sweating, and palpitation. It is advised to monitor your blood sugar levels if you experience the above symptoms. Do not discontinue any medication without consulting a doctor.
How does the drug interact with Lipicure-CV 40 Capsule:
Taking cabozantinib together with Lipicure-CV 40 Capsule may increase the risk of bleeding.

How to manage the interaction:
Taking Lipicure-CV 40 Capsule with Cabozantinib together can result in an interaction, but it can be taken if your doctor has advised it. Contact your doctor immediately if you notice symptoms like bleeding, bruising, dizziness, or black stools. Do not stop using any medications without a doctor's advice.
How does the drug interact with Lipicure-CV 40 Capsule:
When taken together omeprazole can lower the levels of Lipicure-CV 40 Capsule in the blood, which can result in a decreased effectiveness of Lipicure-CV 40 Capsule.

How to manage the interaction:
Taking omeprazole and Lipicure-CV 40 Capsule together has an interaction, but you can take these medications together if a doctor has advised it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Lipicure-CV 40 Capsule:
Taking regorafenib together with Lipicure-CV 40 Capsule may increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Lipicure-CV 40 Capsule and Enoxaparin, but it can be taken if prescribed by a doctor. However, If you experience any unusual bleeding or have other signs of bleeding like feeling dizzy or lightheaded, red or black, sticky stools, or severe headache, consult your doctor immediately. Do not discontinue any medication without consulting your doctor.
How does the drug interact with Lipicure-CV 40 Capsule:
Taking loperamide with Lipicure-CV 40 Capsule may significantly increase the blood levels of loperamide. This can lead to serious and complications such as irregular heart rhythm.

How to manage the interaction:
Although talking Lipicure-CV 40 Capsule with loperamide may result in an interaction, it can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, or shortness of breath. Do not discontinue any medications without consulting a doctor.
ClopidogrelProtamine
Severe
How does the drug interact with Lipicure-CV 40 Capsule:
Taking Protamine with Lipicure-CV 40 Capsule can increase the risk of bleeding.

How to manage the interaction:
Taking Protamine with Lipicure-CV 40 Capsule together can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A low-cholesterol diet along with a regular exercise regimen is found to complement treatment with Lipicure-CV 40 Capsule effectively.
  • Stick to a freshly prepared home-cooked meal and avoid processed, packaged foods that contain hidden sugar and extra calories.
  • Try to replace most of your saturated fats with unsaturated fats to reduce total cholesterol and LDL cholesterol (bad cholesterol) quickly.
  • Foods like avocados, olive oil, fatty fish and nuts contain many heart-healthy unsaturated fats, so eating them regularly is beneficial.
  • Include a diet enriched in fats like fish oils, polyunsaturated oils, and omega-3 fatty acids, which are good for heart health.
  • Quit smoking and avoid excessive intake of alcohol.

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS
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Alcohol

Unsafe

Lipicure-CV 40 Capsule should not be taken with alcohol as it may worsen your liver condition with increased secretion of liver enzymes like transaminase. Keep your doctor informed if you drink alcohol.

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Pregnancy

Unsafe

Lipicure-CV 40 Capsule contains atorvastatin, which is a pregnancy category X medicine. It may cause harm to both the pregnant mother and the fetus. Hence, it is not recommended for pregnant women and those who are planning a pregnancy. Your doctor might prescribe it only in an extreme case.

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Breast Feeding

Consult your doctor

Take Lipicure-CV 40 Capsule only when prescribed, as it is known to pass on in a limited quantity via breast milk to the child.

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Driving

Unsafe

Drive with caution, Lipicure-CV 40 Capsule usually causes blurry vision and may affect driving ability.

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Liver

Caution

Lipicure-CV 40 Capsule to be taken with caution, especially if you have a history of liver disease. The dose may have to be adjusted by your doctor.

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Kidney

Caution

Lipicure-CV 40 Capsule to be taken with caution, especially if you have a history of kidney disease. The dose may have to be adjusted by your doctor.

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Children

Unsafe

Lipicure-CV 40 Capsule is not recommended for children below the age of 10 years. The safety and effectiveness of Lipicure-CV 40 Capsule have not been established in children due to limited testing of Lipicure-CV 40 Capsule on children by competent authorities worldwide.

Have a query?

FAQs

Lipicure-CV 40 Capsule is used to treat Hyperlipidemia (Increased cholesterol), heart attack prevention, and stroke prevention.

Yes, Lipicure-CV 40 Capsule contains clopidogrel which prevents blood clotting. It works by preventing platelets (a type of blood cell) from sticking together and forming clots which in turn prevents the risk of heart attack and stroke.

Yes, taking Lipicure-CV 40 Capsule can increase the risk of bleeding as it contains aspirin and clopidogrel, which belong to a class of blood-thinning agents. So, please be very cautious while shaving, cutting fingernails or toenails, or using sharp objects to avoid any bleeding. Let your doctor know before undergoing any surgical procedure that you are taking Lipicure-CV 40 Capsule .

No. Lipicure-CV 40 Capsule contains Atorvastatin, which is a pregnancy category X medicine and can cause harm to both the pregnant mother and the unborn baby. Even if you are planning for pregnancy, tell your doctor that you are using Lipicure-CV 40 Capsule .

Yes, prolonged use of Lipicure-CV 40 Capsule may cause muscle diseases like myopathy and rhabdomyolysis. So if you feel any musculoskeletal pain after taking Lipicure-CV 40 Capsule consult your doctor about this issue.

Do not drink grapefruit juice while taking Lipicure-CV 40 Capsule . Grapefruit juice may increase the blood-thinning effect of your medicine.

Drinking alcohol with Lipicure-CV 40 Capsule may damage your liver and increase liver enzymes like transaminase. So, Lipicure-CV 40 Capsule should be used with caution by those who consume alcohol and/or have a past history of liver disease.

If you accidentally take an overdose of Lipicure-CV 40 Capsule you may have liver problems (increased secretion of liver enzymes) and bleeding complications. If problems persist you should immediately go to the nearby clinic or hospital.

You should have a total lipid profile (TG, HDL, LDL, VLDL, TC) and Blood coagulation tests like Complete blood count (CBC), Factor V assay, Fibrinogen Test, Prothrombin time (PT or PT-INR), Platelet count, Thrombin time and Bleeding time to analyze your blood clot timing and cholesterol level.

Lipicure-CV 40 Capsule may cause acidity in some cases. Stick to simple meals and avoid spicy food. Do not lie down immediately after eating, as it might cause acidity.

Include fruits, vegetables, and whole grains in your diet. Avoid smoking and drinking, and try to work out every day.

Do not discontinue Lipicure-CV 40 Capsule without consulting your doctor. Stopping using Lipicure-CV 40 Capsule may worsen your condition and increase your risk of a future heart attack. To treat your condition effectively, keep taking Lipicure-CV 40 Capsule for the prescribed duration.

Yes, Lipicure-CV 40 Capsule is good for cholesterol. It lowers bad cholesterol and increases the levels of good cholesterol.

As Lipicure-CV 40 Capsule may increase the risk of bleeding, the doctor may ask you to stop taking Lipicure-CV 40 Capsule before surgery or a dental procedure. Inform the doctor that you are taking Lipicure-CV 40 Capsule if you are due to undergo any surgery.

A low cholesterol diet along with a regular exercise regime is found to complement treatment with Lipicure-CV 40 Capsule effectively. Avoid fast foods, fried and processed foods.

Paracetamol may be safe while taking Lipicure-CV 40 Capsule as other painkillers may increase the risk of bleeding. However, consult the doctor before taking any painkillers with Lipicure-CV 40 Capsule .

Consult the doctor before taking other medicines like antibiotics, anti-HIV drugs, antifungal medication, blood thinners, anti-arthritis drugs, heart-related medicines and immune system-affecting drugs with Lipicure-CV 40 Capsule .

Store Lipicure-CV 40 Capsule at room temperature, in a dry place. Keep out of sight and reach of children.

Side effects of Lipicure-CV 40 Capsule include headaches, ankle swelling (oedema), slow heart rate, and nausea. If the side effects are persistent, reach out to your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - LIP0380

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