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compositionComposition:LEVOBUPIVACAINE-5MG
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Prescription Medicine
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Levo-Bupifix 0.5% Injection 20 ml is used to reduce pain and discomfort during medical procedures. Levo-Bupifix 0.5% Injection 20 ml contains Levobupivacaine as an active ingredient, which belongs to the group of medicines called 'amide-type anaesthetics'. It works by acting on the nervous system and nerves to block the transmission of pain signals in the pain area, which results in the loss of pain. Occasionally Levo-Bupifix 0.5% Injection 20 ml may cause side effects such as weakness, tingling, restlessness, drowsiness, headache, blurred vision, difficulty speaking, irregular heartbeat, chills or shivering, back pain, nausea and vomiting.

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Written By Dr. Lakshmithulasi Yarragunta , PharmD (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

LEVOBUPIVACAINE-5MG

Manufacturer/Marketer :

VARENYAM HEALTHCARE PVT LTD

Consume Type :

Parenteral

Expires on or after :

Dec-28

Return Policy :

Not Returnable

About Levo-Bupifix 0.5% Injection 20 ml

Levo-Bupifix 0.5% Injection 20 ml is a sterile injection used to block pain and provide targeted numbing during surgical procedures, childbirth, and diagnostic tests. It works by temporarily blocking the pathways that send pain signals from specific parts of your body to your brain. This medicine is primarily used in clinical settings to ensure your comfort during medical procedures.

Because Levo-Bupifix 0.5% Injection 20 ml is a specialised injection, it is given as a single dose or as a continuous infusion by a healthcare professional, so you do not need to worry about managing a regular daily schedule. Since this medicine is managed entirely by your medical team in a hospital or clinic, you will not have to take it at home. Resting quietly after your procedure and staying hydrated are simple lifestyle steps that can help support your body's recovery.

While this medicine is highly effective for pain management, you may experience common side effects such as low blood pressure, nausea, or mild headaches. These effects are usually temporary and wear off as the medicine leaves your system, but you must tell your medical team immediately if you notice severe dizziness, blurred vision, or a slow heartbeat.

Before receiving Levo-Bupifix 0.5% Injection 20 ml, it is important to share your complete medical history with your healthcare provider. Do not receive this medicine if you have had a severe allergic reaction to similar numbing medications in the past. You should also discuss alternative options if you have severe heart problems or a major blood infection.

This injection can interact with certain other medicines, such as drugs used to treat irregular heartbeats, which can increase the risk of strain on your heart. If you are pregnant, breastfeeding, or an older adult, discuss your health status with your doctor to ensure this is the safest option for your pain relief.

Uses of Levo-Bupifix 0.5% Injection 20 ml

Levo-Bupifix 0.5% Injection 20 ml is used to provide local or regional anaesthesia for surgical procedures, childbirth, and pain management. It may be prescribed for the following purposes:

  • Surgical pain relief (Anaesthesia): Levo-Bupifix 0.5% Injection 20 ml is injected before surgeries, such as caesarean sections or major abdominal operations, to completely numb the area and prevent pain.
  • Labour and childbirth pain management: It is given as an epidural infusion to help mothers manage pain during labour while remaining awake and alert.
  • Post-operative pain control: It can be used after a surgical procedure to provide continuous, targeted relief, reducing the need for strong oral pain medicines.
  • Nerve block for diagnostic procedures: It is injected near specific nerves to block pain during minor diagnostic tests or localised procedures.

Key Benefits

Levo-Bupifix 0.5% Injection 20 ml offers several advantages that improve pain control during and after medical procedures, including:

  • Targeted pain relief: Levo-Bupifix 0.5% Injection 20 ml provides highly localised numbing. Only the specific area undergoing surgery or treatment is affected, leaving the rest of your body feeling normal and keeping you comfortable throughout the procedure.
  • Reduced need for strong painkillers: By managing pain directly at the source, this medicine often reduces the need for strong oral pain medicines (such as opioids) after surgery, helping minimise side effects like excessive drowsiness, nausea, and dependence.
  • Supports a more comfortable recovery: Effective pain control allows you to rest more comfortably immediately after surgery, which supports the healing process and helps you begin moving sooner under medical supervision.

Directions for Use

  • Levo-Bupifix 0.5% Injection 20 ml is administered the doctor or healthcare professional.
  • Do not self-administer it.

How Levo-Bupifix 0.5% Injection 20 ml Works

Levo-Bupifix 0.5% Injection 20 ml contains levobupivacaine, a local anaesthetic that helps prevent pain during and after surgical procedures or other medical interventions. Levo-Bupifix 0.5% Injection 20 ml works by blocking the movement of sodium into nerve cells. Nerves need sodium to generate and transmit electrical signals, including pain signals. By preventing these signals from being sent, Levo-Bupifix 0.5% Injection 20 ml temporarily stops the sensation of pain from reaching the brain. When injected near specific nerves or into the area requiring pain relief, Levo-Bupifix 0.5% Injection 20 ml produces a targeted loss of sensation while the medicine is active. As the medicine gradually wears off, normal nerve function, sensation, and movement return. Together, these actions provide effective pain relief during and after medical procedures, helping improve patient comfort while allowing normal nerve function to recover over time.
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Alcohol

Unsafe

Avoid alcohol consumption as it may cause increased drowsiness.

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Pregnancy

Caution

Levo-Bupifix 0.5% Injection 20 ml may be unsafe to use during pregnancy as it may show harmful effects on the foetus. Please consult your doctor before receiving Levo-Bupifix 0.5% Injection 20 ml if you are pregnant or planning to conceive.

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Breast Feeding

Safe if prescribed

Levo-Bupifix 0.5% Injection 20 ml passes into breastmilk. Hence, if you are breastfeeding, inform your doctor before receiving Levo-Bupifix 0.5% Injection 20 ml. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Driving

Caution

Levo-Bupifix 0.5% Injection 20 ml will be administered before surgical procedures.

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Liver

Caution

Patients with hepatic disease should use Amide local anaesthetics, like levobupivacaine, with caution, as the liver metabolizes these drugs. Individuals who suffer from severe liver disease are more susceptible to toxic plasma concentrations due to their impaired ability to metabolize local anaesthetics safely.

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Kidney

Consult your doctor

Limited information is available on the use of Levo-Bupifix 0.5% Injection 20 ml in patients with kidney problems. Hence, If you have a pre-existing or a history of kidney disease, inform your doctor before receiving Levo-Bupifix 0.5% Injection 20 ml.

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Children

Consult your doctor

Levo-Bupifix 0.5% Injection 20 ml is recommended for infiltration analgesia (ilioinguinal/iliohypogastric blocks) in children older than six months. Consult your doctor for more information.

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Heart

Caution

Levo-Bupifix 0.5% Injection 20 ml should be used with caution in patients with heart problems, as it may cause bradycardia, hypotension, or even cardiac arrest in rare cases. Always consult your doctor to assess risks and determine if it's safe for your condition.

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Geriatrics

Caution

Levo-Bupifix 0.5% Injection 20 ml can be used in geriatric patients, but age-related changes in heart, liver, or kidney function may increase sensitivity to its effects. Doctors usually adjust the dose and monitor closely to minimize risks like low blood pressure or prolonged numbness.

What if I have taken an overdose of Levo-Bupifix 0.5% Injection 20 ml

Since this medicine is injected by trained medical staff, an overdose is extremely rare. However, if you are receiving a continuous infusion at home and experience sudden dizziness, a metallic taste, or breathing difficulties, stop the infusion if possible and seek immediate emergency medical attention.

Diet & Lifestyle Advise

  • Hydration: Drink plenty of fluids after your procedure (if permitted by your doctor) to help support your blood pressure and flush the medicine from your system.
  • Protect the Numbed Area: Because you will not be able to feel pain or temperature in the numbed part of your body for several hours, avoid touching hot objects, applying heating pads, or putting weight on the area to prevent accidental injury.
  • Rest and Gradual Movement: Rest quietly until the numbing effect has completely worn off. When you start moving again, do so slowly and always with assistance to prevent falls, as your legs or muscles may still feel weak.
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How Soon It Starts Working

The time required for Levo-Bupifix 0.5% Injection 20 ml to start to work: Levo-Bupifix 0.5% Injection 20 ml ideally shows its action within 15 minutes after administration. The time for which the effects of Levo-Bupifix 0.5% Injection 20 ml last: The effect of Levo-Bupifix 0.5% Injection 20 ml lasts for 16 hours.

What if you forget to take Levo-Bupifix 0.5% Injection 20 ml

Because this medicine is given only by healthcare providers in a clinical setting for specific procedures, missing a dose is not a typical concern. The medical team will manage your pain relief schedule during your stay.

Storage

• It must be kept at a controlled room temperature, between 20°C to 25°C (68°F to 77°F).

Drug Warnings

  • Inspect the solution: Ensure the healthcare team checks the injection vial before use. The solution should be clear, colourless, and free from visible particles.
  • Avoid driving: Do not drive, operate heavy machinery, or perform activities requiring full alertness until your doctor confirms the effects of the medicine have completely worn off.
  • Report unusual symptoms immediately: Tell your doctor or nurse straight away if you experience tingling around your mouth, a metallic taste, ringing in your ears, or any sudden changes during or shortly after the injection.
  • Care for an epidural or nerve block catheter: If a catheter has been left in place, keep the insertion site clean and dry, and avoid pulling, bending, or putting pressure on the tubing.

Drug-Drug Interactions

verifiedApollotooltip

These medicines may interact with Levo-Bupifix 0.5% Injection 20 ml and increase the risk of side effects or affect how it works: 

  • Other local anaesthetics: Using other numbing medicines at the same time can increase the risk of serious side effects on your heart and nervous system.
  • Heart rhythm medications (Antiarrhythmics): Combining Levo-Bupifix 0.5% Injection 20 ml with medicines that treat irregular heartbeats can cause a serious strain on your heart function.
No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip

No clinically significant food interactions are known with Levo-Bupifix 0.5% Injection 20 ml when used as directed.

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[LOCAL ANESTHETICS]

FAQs

Levo-Bupifix 0.5% Injection 20 ml is used for Surgical Anaesthesia and Pain Management.
Levo-Bupifix 0.5% Injection 20 ml temporarily blocks the pain signals from the nerves of the painful area to the brain, causing numbness at the affected site and relieving pain.
Levo-Bupifix 0.5% Injection 20 ml may affect your blood pressure. It is advised to inform your doctor before using Levo-Bupifix 0.5% Injection 20 ml if you have high blood pressure during pregnancy or low blood pressure.
In addition to Levo-Bupifix 0.5% Injection 20 ml, your doctor may prescribe certain other medications to help with pain management. This may help you get quick results and make you less prone to the side effects of other pain-relieving medicines.
No, you should not take Levo-Bupifix 0.5% Injection 20 ml on your own; it should be used only if prescribed by the doctor. Levo-Bupifix 0.5% Injection 20 ml is a local anaesthetic that requires administration by a qualified healthcare professional. Do not self-administer Levo-Bupifix 0.5% Injection 20 ml.
Levo-Bupifix 0.5% Injection 20 ml contains levobupivacaine as an active ingredient, which belongs to the group of medicines called amide-type anaesthetics.
No, it is not an opioid or narcotic. Levo-Bupifix 0.5% Injection 20 ml is a local anaesthetic.
In some cases, your doctor may prescribe other medicines in addition to Levo-Bupifix 0.5% Injection 20 ml for pain relief. However, consult your doctor before taking other medicines in addition to Levo-Bupifix 0.5% Injection 20 ml.
Ropivacaine might be safer than Levo-Bupifix 0.5% Injection 20 ml as it is less toxic to the heart compared to levobupivacaine. However, the doctor will prescribe which drug is safe for you based on your condition.
Seizures, airway problems, cardiac arrhythmias, and hypotension are the symptoms of local anaesthesia toxicity. If you experience any of these symptoms, consult your doctor immediately.
The common side effects of Levo-Bupifix 0.5% Injection 20 ml include weakness, tingling, restlessness, drowsiness, headache, blurred vision, difficulty speaking, irregular heartbeat, chills or shivering, back pain, nausea and vomiting. These side effects may not be similar to everyone and vary individually. If any of these side effects bother you, inform your doctor.
Yes, it is commonly used as an epidural to manage labour pain and is generally considered safe for both the mother and the baby when given by an experienced anaesthesiologist. Talk to your doctor or pharmacist if you have concerns.
No, you should not drive or operate machinery immediately after receiving Levo-Bupifix 0.5% Injection 20 ml. The medicine can affect your reflexes, muscle strength, and balance even after the numbing feeling starts to fade. Talk to your doctor about when it is safe to drive.
Tell your healthcare provider immediately. A metallic taste, ringing in your ears, or numbness around your lips can be early signs that the medicine is entering your bloodstream too quickly.
Not necessarily. Levo-Bupifix 0.5% Injection 20 ml is a local or regional anaesthetic, meaning it only numbs a specific part of your body. You may remain fully awake and alert during the procedure, or your doctor may combine it with a sedative to help you relax.
Levo-Bupifix 0.5% Injection 20 ml is designed to provide long-lasting pain relief with a lower risk of affecting your heart or motor function compared to some older numbing medicines. Your doctor will select the best option based on your health profile.
You must inform your doctor about all of your medical conditions, especially any liver damage, heart disease, or allergies to numbing medicines, as well as any prescription or over-the-counter drugs you are taking. Talk to your doctor or pharmacist if you are pregnant or breastfeeding.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Country of origin

India

Manufacturer/Marketer address

Ff/Sf, Sun Welkin Tower-H,Harni-Halol Road'Vadodara, 390022, Gujarat, India.
Other Info - LEV1398
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