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  3. LETHYROX 88MCG TABLET

LETHYROX 88MCG TABLET, Pack of 1 Tablet
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

LETHYROX 88MCG TABLET is used to treat hypothyroidism (underactive thyroid). It contains Levothyroxine which works by restoring the levels of thyroid hormone. In some cases, this medicine may cause side effects such as vomiting, headache, diarrhoea, restlessness, weight loss, or excitability. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Composition :

LEVOTHYROXINE-88MCG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About LETHYROX 88MCG TABLET

LETHYROX 88MCG TABLET belongs to a class of drugs called synthetic thyroid hormones used to treat hypothyroidism (underactive thyroid gland). Hypothyroidism is a chronic condition in which the thyroid gland (located below the throat in the neck) cannot produce enough thyroid hormone.

LETHYROX 88MCG TABLET contains Levothyroxine that replaces thyroxine (a thyroid hormone) naturally produced by the thyroid gland. Thus, it restores the levels of thyroid hormones.

Take LETHYROX 88MCG TABLET as prescribed by your doctor. You are advised to take LETHYROX 88MCG TABLET for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience vomiting, headache, diarrhea, restlessness, weight loss, irregular or fast heartbeat, restlessness, muscle weakness, or excitability. Most of these side effects of LETHYROX 88MCG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to LETHYROX 88MCG TABLET or any other anti-thyroid medicines, please tell your doctor. Usually, the liquid form is recommended for young children. If you are pregnant or breastfeeding, please consult a doctor. If you are about to undergo any surgery, inform your doctor that you are taking LETHYROX 88MCG TABLET. If you have symptoms of a heart attack such as sweating, chest pain or heavy feeling, nausea, general ill feeling, or pain spreading to the shoulder or jaw, do not take LETHYROX 88MCG TABLET and consult a doctor.

Uses of LETHYROX 88MCG TABLET

LETHYROX 88MCG TABLET is used in the treatment of Hypothyroidism (underactive thyroid).

Directions for Use

• It should be taken on an empty stomach, 30 minutes to 1 hour before breakfast, as advised by the doctor.• Follow your doctor's instructions on the dosage and timing of this medication to ensure safety.• Swallow LETHYROX 88MCG TABLET as a whole with a glass of water.• Do not chew, crush or break it.

Medicinal Benefits

LETHYROX 88MCG TABLET contains Levothyroxine, a synthetic thyroid hormone that works by replacing thyroxine (a thyroid hormone) naturally produced by the thyroid gland. Thus, it restores the levels of thyroid hormones.

How LETHYROX 88MCG TABLET Works

LETHYROX 88MCG TABLET contains ‘Sodium acid phosphate’, which binds with the calcium; this helps the calcium levels go back to normal. It also helps in increasing the levels of potassium in the blood. Thereby, LETHYROX 88MCG TABLET helps in treating high calcium and low potassium levels.

Storage

• Store in a cool and dry place away from sunlight.• Keep LETHYROX 88MCG TABLET out of reach and sight of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of LETHYROX 88MCG TABLET

Take LETHYROX 88MCG TABLET only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include fever, angina (chest pain), irregular heartbeat, headache, muscle cramps, flushing, restlessness, diarrhoea, shaking (tremors), sweating, insomnia (difficulty sleeping), and hyperpyrexia (very high temperature). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to LETHYROX 88MCG TABLET or any other anti-thyroid medicines, please tell your doctor. Usually, the liquid form is recommended for young children. If you are pregnant or breastfeeding, please consult a doctor. If you are about to undergo any surgery, inform your doctor that you are taking LETHYROX 88MCG TABLET. LETHYROX 88MCG TABLET is not recommended to treat obesity or weight problems. If you have symptoms of a heart attack such as sweating, chest pain or heavy feeling, nausea, general ill feeling, pain spreading to the shoulder or jaw, do not take LETHYROX 88MCG TABLET and consult a doctor. If you have recently received radiation therapy with iodine such as I-131, inform your doctor before taking LETHYROX 88MCG TABLET.

Drug-Drug Interactions

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Levothyroxine sodiumTirzepatide
Moderate

Drug-Drug Interactions

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Levothyroxine sodiumTirzepatide
Moderate
How does the drug interact with Lethyrox 88mcg Tablet:
Lethyrox 88mcg Tablet may interfere with blood glucose control and decrease the effectiveness of diabetic treatments.

How to manage the interaction:
Inform doctor about all other medications administering, including vitamins and herbs, is crucial. Consult doctor before stopping any medications.

Drug-Food Interactions

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LEVOTHYROXINE-88MCGCalcium rich foods
Moderate

Drug-Food Interactions

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LEVOTHYROXINE-88MCGCalcium rich foods
Moderate
Common Foods to Avoid:
Tofu Set With Calcium, Ragi, Seasame Seeds, Kale, Milk, Almonds, Bok Choy, Calcium-Fortified Soy Milk, Cheese, Yogurt

How to manage the interaction:
Consumption of calcium supplements/calcium-rich foods, along with Lethyrox 88mcg Tablet may create an insoluble compound that affects the absorption of Lethyrox 88mcg Tablet. Avoid consumption of calcium supplements/calcium-rich foods during treatment with Lethyrox 88mcg Tablet.

Diet & Lifestyle Advise

  • Iodine, zinc, and selenium are beneficial for people with hypothyroidism. However, it’s best to avoid iodine and selenium supplements unless your doctor advises you to take them.
  • Hypothyroidism usually involves a loss of calcium (hypocalcemia) and Vitamin D in the body. In such a case, people with hypothyroidism should opt for calcium-enriched foods.
  • Eat more protein as it may help boost your metabolism as people with hypothyroidism usually have a slower metabolism.
  • Do regular yoga and aerobics exercises to boost the metabolism.
  • Eat more vegetables, fruits, and lean meats. These foods are low in calories and may help prevent weight gain.
  • Avoid taking Goitrogens (agents that interfere with the thyroid gland's normal function), which generally includes soy foods (tofu), cabbage, broccoli, kale, cauliflower, spinach, sweet potatoes, cassava, peaches, strawberries, millet, pine nuts, peanuts, etc.

Habit Forming

No

Therapeutic Class

THYROID AND ANTITHYROID AGENTS

LETHYROX 88MCG TABLET Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Consult your doctor

The interaction of LETHYROX 88MCG TABLET with alcohol is unknown. Please consult a doctor before consuming alcohol while using LETHYROX 88MCG TABLET.

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Pregnancy

Consult your doctor

Please consult a doctor if you are pregnant. LETHYROX 88MCG TABLET is given to pregnant women if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Consult your doctor

Please consult a doctor if you are breastfeeding. Your doctor may adjust the dose appropriately if you are breastfeeding.

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Driving

Safe if prescribed

LETHYROX 88MCG TABLET usually does not affect your ability to drive or operate machinery.

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Liver

Consult your doctor

If you have any concerns regarding the use of LETHYROX 88MCG TABLET in patients with Liver problems, please consult a doctor.

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Kidney

Consult your doctor

If you have any concerns regarding using LETHYROX 88MCG TABLET in patients with kidney problems, please consult a doctor.

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Children

Caution

Your doctor may adjust the dose according to your child's age, weight and other pre-existing conditions. LETHYROX 88MCG TABLET should be used for children as advised by the doctor.

Have a query?

FAQs

LETHYROX 88MCG TABLET is used to treat hypothyroidism (underactive thyroid gland).

LETHYROX 88MCG TABLET contains Levothyroxine that works by replacing thyroxine (a thyroid hormone) naturally produced by the thyroid gland. Thus, it restores the levels of thyroid hormones.

LETHYROX 88MCG TABLET should be used with caution in diabetic patients as it may increase blood sugar levels. Therefore, inform your doctor if you have diabetes so that the dose may be adjusted appropriately.

Hair loss may occur during the first few months of treatment in children. This effect is usually temporary, and hair regrows. If this effect persists or worsens, tell your doctor for further treatment.

You are not recommended to take LETHYROX 88MCG TABLET with phenytoin (anticonvulsant) as it may reduce the effectiveness of LETHYROX 88MCG TABLET. However, please consult a doctor before taking LETHYROX 88MCG TABLET with other medicines.

LETHYROX 88MCG TABLET may cause thyroid crisis (severe reaction to high thyroid hormone levels) in some patients. However, if you experience a fast heart rate, confusion, fits, low blood pressure, jaundice, very high fever, or irregular heartbeat, please consult a doctor immediately.

No, LETHYROX 88MCG TABLET should not be used for the treatment of obesity or for weight loss. It is used to treat hypothyroidism. However, taking LETHYROX 88MCG TABLET can lead to weight loss, mainly due to losing water weight. As your thyroid hormone levels become balanced, you may expect to lose up to 10% of your body weight. This weight loss is often most noticeable when you first start the medication.

Take LETHYROX 88MCG TABLET once daily in the morning, at least 30 minutes before breakfast, or caffeinated drinks like tea or coffee. This helps your body absorb the medication properly, ensuring it works effectively. Food and caffeine can interfere with absorption, so it's best to take it on an empty stomach.

Do not stop taking LETHYROX 88MCG TABLET without talking to your doctor. Stopping it suddenly can cause recurring symptoms like fatigue, dry skin, thinning hair, and weight gain. As hypothyroidism is a chronic condition, you may need to take LETHYROX 88MCG TABLET for life. Talk to the doctor if you have any difficulties while taking LETHYROX 88MCG TABLET.

Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include fever, angina (chest pain), irregular heartbeat, headache, muscle cramps, flushing, restlessness, diarrhoea, shaking (tremors), sweating, insomnia (difficulty sleeping), and hyperpyrexia (very high temperature). If you take too much levothyroxine or experience any of these symptoms contact your doctor immediately.

You are recommended to take LETHYROX 88MCG TABLET for as long as it has been prescribed by the doctor. As hypothyroidism is a chronic condition, you may need to take LETHYROX 88MCG TABLET for life. Consult the doctor if you have any concerns regarding the duration of treatment.

Swallow it as a whole with a glass of water. Do not crush, chew, or break it.

If you are diabetic, you should be aware that LETHYROX 88MCG TABLET might raise blood sugar levels. Therefore, dose adjustment of anti-diabetic medicines may be needed. Keep your doctor informed if you are diabetic to ensure your diabetes and thyroid conditions are well-managed.

Thyroxine is a vital hormone that helps your body work properly. It regulates how your body uses energy, affects your heart rate, and helps your brain, muscles, and bones work correctly.

LETHYROX 88MCG TABLET does not affect contraception. However, combined pills which contain oestrogen may lower the amount of levothyroxine in the body. Therefore, talk to the doctor if you are taking a combined pill during treatment with LETHYROX 88MCG TABLET. Also, contraceptives may not be effective if you have vomiting or diarrhoea for over 24 hours while taking LETHYROX 88MCG TABLET.

The common side effects of LETHYROX 88MCG TABLET may include vomiting, headache, diarrhoea, restlessness, weight loss, irregular or fast heartbeat, restlessness, muscle weakness, or excitability. Most of these side effects of LETHYROX 88MCG TABLET do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
Other Info - LET0025

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:28 PM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.435.pdf
  2. https://www.medicines.org.uk/emc/files/pil.4305.pdf
  3. https://www.drugs.com/levothyroxine.html
  4. https://www.medsafe.govt.nz/consumers/cmi/l/levothyroxine.pdf
  5. https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/021342s023lbl.pdf

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