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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Leforin PP Tablet is used to treat the allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat. It works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Also, it inhibits the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever. Some people may experience drowsiness, headache, tiredness, stomach upset, restlessness, and dry mouth. Before taking this medicine, you should tell your doctor if you are allergic to any of its components or if you are pregnant/breastfeeding, and about all the medications you are taking and pre-existing medical conditions.
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About Leforin PP Tablet

Leforin PP Tablet is a cough and cold medication used to treat allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by viruses known as 'rhinovirus'. This virus attacks the body through the mouth, nose, or eyes and spreads easily through droplets in the air when a person who is sick sneezes, coughs, or talks.

Leforin PP Tablet is composed of three medicines, namely Levocetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Take Leforin PP Tablet with or without food as prescribed by your doctor. Do not crush, chew, or break it. If Leforin PP Tablet is in syrup form, measure it with a measuring cup. Your doctor will recommend how often you take Leforin PP Tablet based on your medical condition. Some people may experience drowsiness, headache, tiredness, stomach upset, restlessness, and dry mouth. Most of these side effects of Leforin PP Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Leforin PP Tablet or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Leforin PP Tablet. It should be used with caution in children only if prescribed by a doctor. If you have high blood pressure, kidney or liver problems, coronary artery disease (heart problems), or are receiving any monoamine oxidase inhibitor (MAO) therapy to treat depression like Isocarboxazid, Phenelzine, Selegiline, Tranylcypromine etc., inform your doctor before taking Leforin PP Tablet. Do not drink alcohol with Leforin PP Tablet as it may potentiate the dizziness property of Cetrizine. Hence, it is advisable not to drive or operate heavy machinery or do hazardous work, which requires mental alertness. Taking more than 4 gm per day of paracetamol can damage your liver severely, so if you have liver problems, please contact your doctor.

Uses of Leforin PP Tablet

Treatment of Allergies, Common cold.

Directions for Use

• Leforin PP Tablet can be taken with or without food, as advised by your doctor.• It is usually taken twice daily or as prescribed by your doctor.• Swallow Leforin PP Tablet as a whole with a glass of water.• Do not crush, chew, or break it.

Medicinal Benefits

Leforin PP Tablet is primarily used to treat common cold symptoms and reduce symptoms of allergies. It is composed of three medicines, namely Levocetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps shrink the blood vessels in the nostrils and the passage and reduces stuffy noses. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

How Leforin PP Tablet Works

Leforin PP Tablet is composed of three medicines, namely Levocetirizine (antihistamine/antiallergic), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.  It helps relieve allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nasal passage, thereby reducing a stuffy nose. Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

Storage

Keep Leforin PP Tablet out of the sight and reach of children.

What if I have taken an overdose of Leforin PP Tablet

Do not take more than the prescribed dose of Leforin PP Tablet as it may cause overdose. If you suspect you have taken overdose, please consult a doctor immediately.

Drug Warnings

Do not take Leforin PP Tablet if you are allergic to Leforin PP Tablet or any of its ingredients, are pregnant or breastfeeding before starting Leforin PP Tablet. If you have high blood pressure,  kidney or liver disease, coronary artery disease, please do not take Leforin PP Tablet as it is known to interact. Also, inform your doctor about all other medications you have been taking before starting Leforin PP Tablet. Do not stop taking Leforin PP Tablet even if you feel better without asking your doctor as your symptoms may come back and may even worsen your condition. Leforin PP Tablet may cause drowsiness and sleepiness, so it is advised not to drive a car or operate machinery. Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. Do not take Leforin PP Tablet if you have taken any MAO inhibitor (anti-depressant medication) in the past 14 days.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Leforin PP Tablet:
Co-administration of Leforin PP Tablet with Sevoflurane can increase the levels of Leforin PP Tablet and lead to side effects.

How to manage the interaction:
Taking Leforin PP Tablet with Sevoflurane is not recommended, it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Leforin PP Tablet:
Taking Furazolidone with Leforin PP Tablet can cause an increase in high blood pressure.

How to manage the interaction:
Taking Furazolidone with Leforin PP Tablet is not recommended, it can be taken if prescribed by the doctor. However, if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sweating, lightheadedness, fainting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, consult the doctor immediately. It is advised to use Leforin PP Tablet only after 14 days of stopping Furazolidone.
How does the drug interact with Leforin PP Tablet:
Taking Leforin PP Tablet with Propofol may lead to increased levels of Leforin PP Tablet leading to side effects like high blood pressure.

How to manage the interaction:
Taking Leforin PP Tablet with Propofol is not recommended, but it can be taken if prescribed by the doctor. Do not discontinue the medications without consulting a doctor.
How does the drug interact with Leforin PP Tablet:
Co-administration of Selegiline with Leforin PP Tablet together can raise blood pressure.

How to manage the interaction:
Taking Selegiline with Leforin PP Tablet is not recommended, it can be taken together if prescribed by a doctor. However, consult a doctor immediately if you experience any symptoms such as severe headache, blurred vision, confusion, fits, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting Do not discontinue any medications without consulting a doctor.
How does the drug interact with Leforin PP Tablet:
Taking Tranylcypromine with Leforin PP Tablet can increase the risk of high blood pressure.

How to manage the interaction:
Taking Tranylcypromine with Leforin PP Tablet is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and fainting Do not discontinue any medications without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Leforin PP Tablet:
Co-administration of Mipomersen with Leforin PP Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Leforin PP Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Leforin PP Tablet:
Co-administration of Teriflunomide with Leforin PP Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Leforin PP Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Leforin PP Tablet:
Co-administration of Lomitapide and Leforin PP Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Leforin PP Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolValdecoxib
Severe
How does the drug interact with Leforin PP Tablet:
Co-administration of Leforin PP Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Leforin PP Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
How does the drug interact with Leforin PP Tablet:
Co-administration of Leforin PP Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Leforin PP Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands with soap and water regularly to prevent the spread of germs.

  • Eat plenty of foods rich in good bacteria like yoghurt to improve overall health. 
  • Drink plenty of fluids to avoid dehydration.
  • Gargle with salt water for relief from sore throat.
  • Avoid alcohol consumption with Leforin PP Tablet as it may cause tiredness, drowsiness, or lack of concentration.

Habit Forming

No

Therapeutic Class

RESPIRATORY STIMULANTS
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Alcohol

Unsafe

Avoid consumption of alcohol with Leforin PP Tablet as it may increase drowsiness. Please consult a doctor before consuming alcohol with Leforin PP Tablet.

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Pregnancy

Caution

The safety of Leforin PP Tablet in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

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Breast Feeding

Caution

The safety of Leforin PP Tablet in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

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Driving

Caution

Leforin PP Tablet may cause drowsiness or tiredness in some people. Therefore, drive only if you are alert after taking Leforin PP Tablet.

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Liver

Caution

Take Leforin PP Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Leforin PP Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Leforin PP Tablet is not recommended for children below 12 years of age. However, please consult a doctor before giving Leforin PP Tablet to children.

Have a query?

FAQs

Leforin PP Tablet is a cough and cold medication primarily used to treat allergies and common cold symptoms like sneezing, runny/stuffy nose, watery eyes, and itchy nose/throat.

Leforin PP Tablet is composed of three medicines, namely Levocetirizine (antihistamine), Phenylephrine (decongestant), and Paracetamol (analgesic and antipyretic). Levocetirizine belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps provide relief from allergy symptoms such as sneezing, running nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps in shrinking the blood vessels in the nostrils and the passage and reducing stuffy nose. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.

No, you are not recommended to stop taking Leforin PP Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Leforin PP Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Leforin PP Tablet, please consult your doctor.

No, you should not take Leforin PP Tablet along with high blood pressure (hypertension) medication, leading to a further rise in blood pressure. Please inform your doctor if you have high blood pressure before starting Leforin PP Tablet.

Yes, Cetirizine present in Leforin PP Tablet may cause drowsiness. It is not necessary for everyone taking Leforin PP Tablet to experience this side effect. Therefore, avoid driving and drinking alcohol if you feel drowsy after taking Leforin PP Tablet.

No, you are not recommended to consume alcohol with Leforin PP Tablet as it may increase drowsiness, dizziness, and lack of concentration.

No, you are not recommended to take Leforin PP Tablet with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness, or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

Common side effects of Leforin PP Tablet may include headache, drowsiness, tiredness, stomach upset, restlessness, and dry mouth. In most cases, these side effects are mild and temporary, resolving on their own over time. However, if any of these side effects persist or worsen, it's essential to consult a doctor for further guidance.

Taking a higher than recommended dose of Leforin PP Tablet will not increase its effectiveness; instead, it may cause serious side effects. Therefore, always follow the dose prescribed by a doctor to treat your medical condition effectively.

To ensure safe use, inform your doctor if you have any allergies or are taking other medications. It's also crucial to avoid concurrent use with St. John's Wort and MAO inhibitors. Pregnant or breastfeeding women should consult their doctor before taking this medication. Additionally, avoid consuming alcohol and only drive if you're feeling alert to minimize potential risks.

The safety of Leforin PP Tablet in breastfeeding mothers is unknown. Therefore, consult a doctor if you are breastfeeding. The doctor may prescribe this medication only if the benefits outweigh the risks.

Leforin PP Tablet should be stored in a cool, dry place away from sunlight. Keep it out of sight and reach of children.

Country of origin

India

Manufacturer/Marketer address

Forgo Pharmaceuticals Private Limited, Plot No. 92, Industrial Area, Phase 1, Panchkula-134109, Haryana, India
Other Info - LE51892

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