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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Laretol Injection 1ml is used to treat hypocalcaemia (low calcium levels). It contains calcitriol. It increases the levels of vitamin D in your blood, which in turn raises calcium levels; thus, it helps treat patients with low levels of calcium who are on chronic renal dialysis. Common side effects of Laretol Injection 1ml may include Nausea, headache, constipation, or pain/discomfort at the injection site may occur.

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Composition :

CALCITRIOL-1MCG

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Laretol Injection 1ml

Laretol Injection 1ml is used to treat or prevent some complications such as low calcium levels (hypocalcemia). Hypocalcaemia is characterized by low levels of calcium in the blood. A lack or inadequacy of vitamin D can cause hypocalcemia.

Laretol Injection 1ml contains calcitriol. It increases the levels of vitamin D in your blood, which in turn raises calcium levels; thus, it helps to treat patients with low levels of calcium who are on chronic renal dialysis.

In some cases, Laretol Injection 1ml can cause side effects like nausea, headache, constipation, or pain/discomfort at the injection site. Most of these side effects of Laretol Injection 1ml do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Before taking the Laretol Injection 1ml, let your doctor know about all your medical conditions, sensitivities, and medications you are using. Inform your doctor if you have too much calcium or vitamin D in the blood before receiving the Laretol Injection 1ml. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Uses of Laretol Injection 1ml

Laretol Injection 1ml is used in the treatment of Hypocalcaemia (low calcium levels). The detailed uses of Laretol Injection 1ml are as follows:

  • Manage Hypocalcemia: Laretol Injection 1ml effectively treats low calcium levels in patients undergoing chronic renal dialysis, helping to regulate calcium balance and support overall bone health.
  • Reduce Elevated Parathyroid Hormone (PTH) Levels: Laretol Injection 1ml significantly lowers PTH levels, improving renal osteodystrophy.

Directions for Use

  • Laretol Injection 1ml should be administered only under the supervision of a healthcare professional.
  • Your healthcare provider will determine the appropriate dose and frequency based on your condition.
  • Self-administration is not recommended.

Medicinal Benefits

  • Laretol Injection 1ml contains calcitriol as an active ingredient.
  • It increases the levels of vitamin D in your blood, which raises calcium levels
  • Laretol Injection 1ml helps treat patients with low levels of calcium who are on chronic renal dialysis.
  • Calcitriol is usually used along with a certain diet, supplements, and sometimes other medications.
  • It can also help to build and keep strong bones.

How Laretol Injection 1ml Works

Laretol Injection 1ml contains calcitriol. It increases the levels of vitamin D in your blood, which in turn raises calcium levels thus, it helps to treat patients with low levels of calcium who are on chronic renal dialysis.

Storage

• Store in a cool and dry place away from sunlight.• Keep Laretol Injection 1ml out of reach and sight of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Laretol Injection 1ml

As Laretol Injection 1ml is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away.

Drug Warnings

  • Before taking the Laretol Injection 1ml, let your doctor know about all your medical conditions, sensitivities, and all medications you are using.
  • Avoid taking Laretol Injection 1ml if you are allergic to it.
  • Inform your doctor if you have malabsorption syndrome (difficulty absorbing nutrition from food) or if you are diagnosed with too much calcium or vitamin D in the blood before receiving the Laretol Injection 1ml.
  • Laretol Injection 1ml should not be used for pregnant and lactating mothers unless clearly necessary. So, inform your doctor if you are a pregnant woman or a nursing mother.
  • Laretol Injection 1ml is not recommended for children below 12 years.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Laretol Injection 1ml:
Co-administration of Cholecalciferol and Laretol Injection 1ml are forms of vitamin D, and taking too much vitamin D may lead to toxic effects.

How to manage the interaction:
Although there is a possible interaction between colecalciferol and Laretol Injection 1ml, you can take these medicines together if prescribed by your doctor. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, dry mouth, strange taste in your mouth, muscle or bone pain, thirst, losing weight, eye infection, sensitivity to light, runny nose or itching - contact a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Laretol Injection 1ml:
Co-administration of Laretol Injection 1ml with Carbamazepine may decrease the effects of Laretol Injection 1ml.

How to manage the interaction:
Although there is an interaction, Laretol Injection 1ml can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
How does the drug interact with Laretol Injection 1ml:
Co-administration of Doxercalciferol and Laretol Injection 1ml are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Doxercalciferol with Laretol Injection 1ml can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
CalcitriolMetolazone
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Metolazone with Laretol Injection 1ml can cause blood calcium levels to become too high.

How to manage the interaction:
Although there is an interaction, Laretol Injection 1ml can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
CalcitriolDigitoxin
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Laretol Injection 1ml with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.

How to manage the interaction:
Although there is an interaction, Laretol Injection 1ml can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
CalcitriolDihydrotachysterol
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Laretol Injection 1ml with Dihydrotachysterol can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Dihydrotachysterol with Laretol Injection 1ml can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Laretol Injection 1ml:
Co-administration of Orlistat with Laretol Injection 1ml may reduce the levels of Laretol Injection 1ml which can lead to low treatment outcomes.

How to manage the interaction:
Although there is an interaction, Laretol Injection 1ml can be taken with Orlistat when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
CalcitriolAmobarbital
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Amobarbital and Laretol Injection 1ml may decrease the effects of Laretol Injection 1ml.

How to manage the interaction:
Co-administration of Laretol Injection 1ml with Amobarbital can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms, it's important to contact a doctor right away. Do not stop using any medications without talking to a doctor.
CalcitriolBurosumab
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Laretol Injection 1ml and Burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.

How to manage the interaction:
There may be a possibility of interaction between Laretol Injection 1ml and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
CalcitriolCalcifediol
Severe
How does the drug interact with Laretol Injection 1ml:
Co-administration of Calcifediol and Laretol Injection 1ml are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to increased calcium levels in the blood and urine.

How to manage the interaction:
Taking Calcifediol with Laretol Injection 1ml can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, headache, fatigue, drowsiness, vertigo, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
  • Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables daily.
  • Snack on calcium-rich nuts like Brazil nuts or almonds.
  • Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
  • Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
  • Replace the meat with tofu or tempeh for extra calcium in your food.

Habit Forming

No

Therapeutic Class

MULTIMINERALS

Laretol Injection 1ml Substitute

Substitutes safety advice
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Alcohol

Caution

Drinking alcohol can affect calcium absorption; hence it is advised to limit the alcohol intake while using Laretol Injection 1ml.

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Pregnancy

Consult your doctor

There are no sufficient and well-controlled studies on pregnant women. Laretol Injection 1ml should be used during pregnancy only if the possible advantages outweigh the potential risks to the foetus. Inform your doctor if you are pregnant before receiving this injection.

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Breast Feeding

Consult your doctor

Laretol Injection 1ml should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. If Laretol Injection 1ml is used during breastfeeding, your doctor may monitor the serum calcium levels of both mother and the infant.

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Driving

Safe if prescribed

Laretol Injection 1ml does not impact your ability to drive or use machinery.

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Liver

Consult your doctor

Inform your doctor before receiving the Laretol Injection 1ml if you have a history of liver disease. Your doctor will weigh the benefits and potential risks before prescribing Laretol Injection 1ml.

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Kidney

Consult your doctor

Inform your doctor before receiving the Laretol Injection 1ml if you have a history of kidney disease. Your doctor may adjust your dose depending on your current kidney conditions.

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Children

Consult your doctor

It is unknown whether Laretol Injection 1ml is safe for children under 12 years old. Please consult your doctor for more information.

Have a query?

FAQs

Laretol Injection 1ml belongs to the class of a vitamin D analogue. Calcitriol is used to treat or prevent some complications associated with long-term kidney dialysis, such as low calcium levels (Hypocalcaemia).

Laretol Injection 1ml contains calcitriol, which works by increasing the amount of calcium in your body. It also helps regulate parathyroid hormone levels. Thus it treats patients with low levels of calcium who are on chronic renal dialysis.

Before taking the Laretol Injection 1ml, let your doctor know about all your medical conditions (especially if you have too much calcium or vitamin D in the blood), all medications you are using (especially Burosumab, Vitamin D) and sensitivities or allergic conditions to medicines or foods.

Parenteral therapy should only be used for patients unable to take oral medications or in an emergency clinical situation.

Country of origin

INDIA

Manufacturer/Marketer address

Behind Rajpath Club, Kensville Road, Opp. Infostretch Building, Off S.G. Highway, Ahmedabad- 380059, Gujarat- India
Other Info - LAR0042

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