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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

Lamictal 50 mg Tablet is used to treat epilepsy/seizures/fits. Additionally, it also treats bipolar disorder. It contains Lamotrigine, which reduces the electrical impulses and firing of the nerve impulses that cause fits. In some cases, this medicine may cause side effects such as headache, nausea, vomiting, dry mouth, dizziness, fatigue, abdominal pain, and infection. Inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.

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Whats That

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Composition :

LAMOTRIGINE-50MG

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Lamictal 50 mg Tablet

Lamictal 50 mg Tablet belongs to a group of anticonvulsants or anti-epileptics used to treat epilepsy/seizures/fits. Additionally, Lamictal 50 mg Tablet also treats bipolar disorder. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading to an unconscious state. Bipolar disorder is a severe brain disorder in which a person experiences extreme mood swings (variance in thinking) and frequent mood and behavioural changes.

Lamictal 50 mg Tablet contains Lamotrigine, which works by blocking sodium channels and reducing the release of glutamate, a brain chemical that can trigger seizures or mood changes. This calms excessive nerve activity, helping control seizures in epilepsy and reducing the risk of mood episodes in bipolar disorder.

You are advised to take Lamictal 50 mg Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as skin rash, headache, nausea, vomiting, dryness in the mouth, insomnia (difficulty in sleeping), sleepiness, dizziness, back pain, fatigue, abdominal pain, blurred vision, double vision, impaired coordination, nasal congestion (stuffy nose), and infection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, do not stop taking Lamictal 50 mg Tablet without consulting your doctor to avoid worsening of seizures. Do not take Lamictal 50 mg Tablet if you are pregnant or planning for pregnancy unless prescribed by the doctor, as it could lead to serious congenital disabilities. If you are of childbearing age, use effective contraception while taking Lamictal 50 mg Tablet . Consult your doctor before taking Lamictal 50 mg Tablet if you are breastfeeding. Contact your doctor if your child gets her first period whilst on treatment with Lamictal 50 mg Tablet . Do not drive or operate machinery as Lamictal 50 mg Tablet causes drowsiness and dizziness. Avoid consuming alcohol along with Lamictal 50 mg Tablet as it could lead to increased dizziness and sleepiness. Consult your doctor immediately if you experience suicidal tendencies.

Uses of Lamictal 50 mg Tablet

Lamictal 50 mg Tablet is used in the treatment of epilepsy (fits) and bipolar disorder. The detailed uses of Lamictal 50 mg Tablet are as follows:

  • Epilepsy/seizures: Lamictal 50 mg Tablet controls seizures by stabilizing abnormal electrical activity in the brain, reducing their frequency and severity.
  • Bipolar Disorder: Lamictal 50 mg Tablet helps prevent mood swings or depressive episodes, maintaining emotional balance in individuals with bipolar disorder.

Directions for Use

  • Take Lamictal 50 mg Tablet with food or as directed by your doctor.
  • Always follow your doctor’s advice regarding the prescribed dosage and duration of treatment.
  • Swallow Lamictal 50 mg Tablet whole with a glass of water.
  • Do not crush, chew, or break the tablet.

Medicinal Benefits

  • Lamictal 50 mg Tablet contains Lamotrigine, which helps control seizures by stabilizing abnormal electrical activity in the brain.
  • It reduces the release of glutamate, a chemical messenger that can trigger seizures, preventing excessive nerve overactivity.
  • It decreases the frequency and severity of seizures in conditions such as partial-onset seizures, primary generalized tonic-clonic seizures, and Lennox–Gastaut syndrome.
  • It helps delay the occurrence of mood episodes (depressive, manic, or mixed) in individuals with Bipolar I Disorder, maintaining long-term emotional balance.
  • It has a well-established safety profile in pediatric epilepsy and is not associated with physical or psychological dependence or abuse potential.

How Lamictal 50 mg Tablet Works

Lamictal 50 mg Tablet contains Lamotrigine, which works by blocking sodium channels and reducing the release of glutamate, a brain chemical that can trigger seizures or mood changes. This calms excessive nerve activity, helping control seizures in epilepsy and reducing the risk of mood episodes in bipolar disorder.

Storage

• Store in a cool and dry place away from sunlight.• Keep Lamictal 50 mg Tablet out of the sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.
Side effects of Lamictal 50 mg Tablet
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

What if I have taken an overdose of Lamictal 50 mg Tablet

Take Lamictal 50 mg Tablet only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include impaired coordination, involuntary eye movement, seizures, decreased level of consciousness, coma, and intraventricular conduction delay (abnormal heart conduction). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

  • Do not take Lamictal 50 mg Tablet if you are allergic to Lamotrigine or its ingredients. Seek immediate medical help if you develop sudden swelling of the face, lips, tongue, or throat, difficulty breathing, or severe skin reactions such as rash, blistering, peeling, or sores in the mouth or around the eyes. These reactions may be life-threatening, especially in children, at high starting doses, or when combined with valproic acid.
  • Inform your doctor about all your existing medical conditions, particularly liver, kidney, or pancreas problems, urea cycle disorders, inflammation of the brain and spinal cord lining, porphyria (a blood pigment disorder), or low platelet levels.
  • Tell your doctor about all medicines, supplements, or herbal products you are taking, as certain drugs may interact with Lamictal 50 mg Tablet and increase the risk of side effects.
  • Do not stop taking Lamictal 50 mg Tablet suddenly without your doctor’s advice, as abrupt withdrawal can cause serious, life-threatening seizures.
  • Consult your doctor before using Lamictal 50 mg Tablet if you are pregnant, planning to become pregnant, or breastfeeding. This medicine may harm the unborn baby and could affect the child’s cognitive abilities (reasoning, intelligence, problem-solving) later in life.
  • Use Lamictal 50 mg Tablet with caution in children, as they may have a higher risk of severe skin reactions and other side effects.
  • Avoid alcohol consumption while taking Lamictal 50 mg Tablet , as it can increase dizziness, drowsiness, and the risk of side effects.
  • Do not drive or operate heavy machinery until you know how Lamictal 50 mg Tablet affects you, as it may cause dizziness, drowsiness, or reduced alertness.

Drug-Drug Interactions

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LamotrigineDofetilide
Critical

Drug-Drug Interactions

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LamotrigineDofetilide
Critical
How does the drug interact with Lamictal 50 mg Tablet:
Taking Dofetilide with Lamictal 50 mg Tablet may significantly increase the blood levels of dofetilide. High blood levels of dofetilide can increase the risk of an irregular heart rhythm that may be serious

How to manage the interaction:
Taking Lamictal 50 mg Tablet with Dofetilide is not recommended, but can be taken together if prescribed by a doctor. However, consult a doctor if you experience sudden dizziness, lightheadedness, fainting and shortness of breath. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lamictal 50 mg Tablet:
Using Ketamine and Lamictal 50 mg Tablet together can increase the risk of side effects.

How to manage the interaction:
Although there is a possible interaction between Ketamine and Lamictal 50 mg Tablet, you can take these medicines together if prescribed by your doctor. If you feel dizzy, sleepy, confused, have trouble focusing, or have trouble breathing, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Lamictal 50 mg Tablet:
When buprenorphine is used with Lamictal 50 mg Tablet, it may possibly lead to significant adverse effects such as respiratory difficulties, unconsciousness.

How to manage the interaction:
Concomitant administration of buprenorphine alongside Lamictal 50 mg Tablet can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery until you're aware of how these medications effect you. Do not discontinue any medications without consulting a doctor.
LamotrigineEsketamine
Severe
How does the drug interact with Lamictal 50 mg Tablet:
Coadministration of Lamictal 50 mg Tablet with Esketamine can increase the risk of serious side effects.

How to manage the interaction:
There may be a possibility of interaction between Lamictal 50 mg Tablet and Esketamine, but it can be taken if prescribed by a doctor. Consult your doctor immediately if you feel drowsiness, trouble breathing, dizziness, loss of balance, or confusion, it is advised not to drive or use any hazardous machinery. Do not stop taking any medication without consulting your doctor.
LamotrigineSodium oxybate
Severe
How does the drug interact with Lamictal 50 mg Tablet:
Taking Lamictal 50 mg Tablet with sodium oxybate can increase the risk and severity of side effects.

How to manage the interaction:
Taking Lamictal 50 mg Tablet with Sodium oxybate together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Lamictal 50 mg Tablet:
Coadministration of Divalproex and Lamictal 50 mg Tablet can increase the risk and severity of side effects.

How to manage the interaction:
Although there is a possible interaction between Divalproex and Lamictal 50 mg Tablet, you can take these medicines together if prescribed by your doctor. However, contact your doctor if you experience restlessness, rash, or muscle weakness. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • A ketogenic diet (low in carbohydrates and high in fats) is recommended for children with epilepsy. This diet helps the body utilise fat instead of glucose for energy generation.
  • The Atkins diet (high fat and controlled carbohydrates) is recommended for adolescents and adults.
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Exercise, meditation, and yoga can help lower stress, decrease pain sensitivity, and improve coping skills.
  • Prepare your living area; small changes may reduce the risk of physical injury during a seizure.
  • Install an alarm or emergency device to get assistance during a seizure attack.

Habit Forming

No

Therapeutic Class

ANTICONVULSANT
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Alcohol

Unsafe

It is advised to avoid alcohol consumption while taking Lamictal 50 mg Tablet . Alcohol intake, along with Lamictal 50 mg Tablet , may cause increased dizziness and drowsiness. Please consult your doctor for more information.

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Pregnancy

Caution

Lamictal 50 mg Tablet is a pregnancy category C drug. Animal studies showed that Lamictal 50 mg Tablet affects the fetus in pregnancy, but there is limited data in humans. Using antipsychotic drugs during the third trimester of pregnancy can cause muscle problems in newborns. Please consult your doctor before taking Lamictal 50 mg Tablet if you are pregnant or planning to conceive.

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Breast Feeding

Caution

It is not known if Lamictal 50 mg Tablet is excreted into the breast milk. Please consult your doctor before taking Lamictal 50 mg Tablet if you are a breastfeeding mother.

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Driving

Unsafe

Lamictal 50 mg Tablet may make you feel dizzy or drowsy. Do not drive if you are not mentally alert or experience any symptoms that affect your ability to drive or operate machinery.

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Liver

Caution

Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.

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Kidney

Caution

Dose adjustment may be needed in patients with kidney impairment. Please consult your doctor if you have kidney impairment or any concerns regarding this.

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Children

Caution

Lamictal 50 mg Tablet can be given to children if prescribed by the doctor. The doctor will adjust the dose.

Have a query?

FAQs

Lamictal 50 mg Tablet is used in the treatment of Epilepsy (fits) and Bipolar disorder. It contains Lamotrigine, which reduces the electrical impulses and subsequent firing of the nerve impulses that cause fits. Lamictal 50 mg Tablet decreases the brain's excessive and abnormal nerve activity, thereby helping control seizures.

Do not discontinue Lamictal 50 mg Tablet without consulting your doctor. To treat your condition effectively, continue taking Lamictal 50 mg Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking Lamictal 50 mg Tablet . Your doctor will reduce the dose gradually to avoid worsening seizures.

Lamictal 50 mg Tablet may cause weight gain due to an increase in appetite. Maintain a healthy weight by following a healthy diet and exercising regularly.

Dry mouth could be a side-effect of Lamictal 50 mg Tablet . Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Lamictal 50 mg Tablet helps to treat manic episodes associated with bipolar disorder by increasing the amount of a chemical substance called GABA, this helps in blocking the nerve transmission across the brain and provides a calming effect.

Lamictal 50 mg Tablet contains Lamotrigine, which works by blocking sodium channels and reducing the release of glutamate, a brain chemical that can trigger seizures or mood changes. This calms excessive nerve activity, helping control seizures in epilepsy and reducing the risk of mood episodes in bipolar disorder.

The side effects of Lamictal 50 mg Tablet include sleepiness, dizziness, tremor, back pain, headache, nausea, vomiting, diarrhoea, blurred or double vision, tiredness, fever, dry mouth, sore throat, stuffy nose, stomach pain and infections, including seasonal flu. However, if these side effects persist or worsen, please consult your doctor.

Epilepsy also called as seizure disorder is a brain-related disorder affecting people of all ages characterized by repeated seizures that are brief episodes of involuntary movement that may involve a part of the body or full body. It is caused due to abnormal electrical activity in the brain and sometimes followed by loss of consciousness and control of bladder or bowel function.

Bipolar disorder also called as manic depression is a mental illness that causes unusual shifts in a person's mood, energy, concentration, and activity levels. It is marked by episodes of mood swings ranging from depressive lows to manic highs.

There have been cases where patients were hospitalized after experiencing severe rashes within 8 weeks of starting Lamictal 50 mg Tablet . Sometimes these rashes progress into severe skin infections and may risk the patient’s life. Therefore, if a patient develops rashes after starting Lamictal 50 mg Tablet , it is recommended that Lamictal 50 mg Tablet should be stopped and should not be restarted. The use of Lamictal 50 mg Tablet is stopped even if the rashes are mild and not serious. This is the reason your doctor changed the medicine.

Though it is different from person to person, it may take about 6-8 weeks for your symptoms to improve.

You may experience uncontrollable and quick eye movements, lack of coordination and clumsiness. High doses of Lamictal 50 mg Tablet may cause changes in heartbeat rhythm, balance problems, loss of consciousness, fits (convulsions) or coma. If you suspect you have taken more than the recommended dose of Lamictal 50 mg Tablet , seek medical help immediately, even if there are no signs of discomfort.

You are recommended to consult your doctor before taking Lamictal 50 mg Tablet with other antiepileptic medicines to avoid drug interactions.

Take Lamictal 50 mg Tablet as advised by the doctor. It can be taken with or without food. Swallow it as whole with a glass of water. Do not break, crush or chew it.

Yes, you can take Lamictal 50 mg Tablet if you have symptoms of depression. In fact, Lamictal 50 mg Tablet is used to prevent depression. However, do not self-medicate. Use Lamictal 50 mg Tablet only if prescribed by a doctor.

Country of origin

India

Manufacturer/Marketer address

24-25 Floor, One Horizon Center Golf Course Road, DLF Phase 5 Gurgaon 122002, India.
Other Info - LAM0119

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