Does Lagipeg Injection 5 ml cause glucose intolerance?

Lagipeg Injection 5 ml may cause glucose intolerance in some people. Consult the doctor if you have high/low blood glucose levels.

How is Lagipeg Injection 5 ml administered?

Lagipeg Injection 5 ml is given as an injection, usually through an intravenous (IV) or intramuscular (IM) route. The dosage and frequency depend on your condition and doctor’s recommendation.

Does Lagipeg Injection 5 ml cause stomach pain?

Lagipeg Injection 5 ml may cause stomach pain in some patients. You are advised to inform your doctor immediately if you experience stomach pain, as it may be a sign of pancreatitis, an inflammation of the pancreas.

Can I drive after receiving Lagipeg Injection 5 ml?

Do not drive or operate machinery while using this medication, as it may cause drowsiness, fatigue, or confusion, which can reduce your ability to concentrate and respond quickly.

What should I do if I have a history of liver complications?

If you have a history of liver complications, inform your doctor before receiving Lagipeg Injection 5 ml, as it can affect liver function. Individuals with a history of liver issues are at higher risk for liver damage. Your doctor will monitor liver function through regular tests and may adjust the dosage if necessary.

Can Lagipeg Injection 5 ml be given to children?

Yes, Lagipeg Injection 5 ml can be administered to children, particularly to treat Acute Lymphoblastic Leukaemia (ALL). However, the dosage and administration are adjusted based on the child's age and weight. Always follow your doctor's recommendations for pediatric use.

What should I avoid during my treatment with Lagipeg Injection 5 ml?

During your treatment with Lagipeg Injection 5 ml, avoid alcohol, infection risks, blood-thinning medications, and unapproved treatments. Check with your doctor before taking any new medications or supplements, and avoid high-fat foods if you experience digestive issues. Consult a doctor if you have any concerns or if any signs of infection occur.

Lagipeg Injection 5 ml

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Reviewed By Santoshini Reddy G , M Pharmacy

Lagipeg Injection 5 ml is used to treat Acute Lymphoblastic Leukaemia, mainly as a first-line treatment. It is also beneficial for patients who are allergic to asparaginase. It works by lowering plasma asparagine, a necessary component for leukaemia cells to survive. Common side effects include nausea, vomiting, diarrhoea, fever, tiredness, and dizziness. Let the doctor know if you are pregnant, breastfeeding, taking other medicines or have pre-existing medical conditions.

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About Lagipeg Injection 5 ml

Lagipeg Injection 5 ml is used in the treatment of Acute Lymphoblastic Leukaemia (ALL) and hypersensitivity to asparaginase. Acute lymphoblastic leukaemia is a type of cancer where the body makes too many abnormal white blood cells. These cells proliferate quickly and interfere with normal blood cell production, causing symptoms such as fatigue and easy bruising. It is more common in children but can also affect adults.

Lagipeg Injection 5 ml contains Pegylated L-asparaginase. It works by reducing asparagine, which is necessary for leukaemia cells to survive. L-asparaginase breaks down asparagine in the blood. Since leukaemia cells cannot produce it on their own, they rely on an external source. With the reduction of asparagine, the leukaemia cells are unable to proliferate and eventually die.

A healthcare professional will administer Lagipeg Injection 5 ml. In some cases, this medicine may cause side effects like nausea, vomiting, diarrhoea, fever, tiredness, and dizziness. The majority of these side effects may not require medical treatment and will subside with time. However, if the side effects persist or worsen, see a doctor.

Before starting treatment, be sure to inform your doctor about any other medications or herbal products you are currently taking. Lagipeg Injection 5 ml is contraindicated for patients with a history of severe allergic reactions, pancreatitis, blood clots, or serious bleeding caused by prior L-asparaginase treatment. Pregnant and breastfeeding women should consult their doctor before receiving Lagipeg Injection 5 ml. This medicine is given to children in doses as advised by the doctor, depending on the age. Lagipeg Injection 5 ml should be stored in cold places at 2°C to 8°C.

Uses of Lagipeg Injection 5 ml

First-line Treatment of Acute Lymphoblastic Leukaemia (ALL): Lagipeg Injection 5 ml is used as the first-line treatment for Acute Lymphoblastic Leukaemia. It works by breaking down the amino acid asparagine, which is required for leukaemia cell survival, thereby reducing proliferation and promoting recovery.<br/>Treatment of Acute Lymphoblastic Leukemia (ALL): Lagipeg Injection 5 ml is also used in the general management of Acute Lymphoblastic Leukemia.<br/>Patients with Hypersensitivity to Asparaginase: Lagipeg Injection 5 ml is used as an alternative in patients who have developed hypersensitivity reactions to other forms of asparaginase. Its PEGylated formulation reduces the risk of immune responses and allows for prolonged therapeutic activity.

Directions for Use

• Follow your doctor's instructions on the dosage and timing of this medication.• Lagipeg Injection 5 ml will be administered by a healthcare professional in a medical setting.• Do not self-administer.

Medicinal Benefits

Lagipeg Injection 5 ml is a pegylated form of L-asparaginase, an enzyme that breaks down L-asparagine. This enzyme specifically targets leukaemia cells in acute lymphoblastic leukaemia (ALL), which cannot produce enough L-asparagine on their own and depend on it from the blood for protein production. It works by breaking down the amino acid asparagine, which leukaemia cells need to proliferate. Its pegylated form reduces the risk of hypersensitivity reactions and provides a longer duration of action, allowing for less frequent dosing. This makes it more tolerable for patients, especially those who have experienced allergic reactions to other forms of asparaginase.

How Lagipeg Injection 5 ml Works

Lagipeg Injection 5 ml contains Pegylated L-asparaginase. It works by reducing asparagine, which is necessary for leukaemia cells to survive. L-asparaginase breaks down asparagine in the blood. Since leukaemia cells cannot produce it on their own, they rely on an external source. With the reduction of asparagine, the leukaemia cells are unable to proliferate and eventually die.

Storage

• Store in a cool and dry place away from sunlight.
• Keep Lagipeg Injection 5 ml out of the sight and reach of children.
• Cold chain - To be stored in cold places at 2ÂºC to 8ÂºC.

What if I have taken an overdose of Lagipeg Injection 5 ml

Lagipeg Injection 5 ml is administered in a controlled medical setting by a healthcare professional, and the likelihood of an overdose is much less. However, if you suspect an overdose or experience any unusual effects, seek medical attention immediately.

Drug Warnings

Inform your doctor if you have had severe allergic reactions to asparaginase, bleeding problems, or blood clots. Let your doctor know if you get a fever, have liver issues, or take medicines that could harm your liver. Lagipeg Injection 5 ml can cause liver damage, brain problems, or pancreas issues. If you experience stomach pain, let your doctor know. Lagipeg Injection 5 ml is contraindicated for patients with a history of severe allergic reactions, pancreatitis, blood clots, or serious bleeding caused by prior L-asparaginase treatment. If you are pregnant, planning for pregnancy, or are breastfeeding, please inform your doctor before receiving Lagipeg Injection 5 ml. Avoid driving after receiving Lagipeg Injection 5 ml if you experience drowsiness or dizziness.

Diet & Lifestyle Advise

Maintain a balanced diet that includes fruits and vegetables rich in nutrients and low-fat proteins, such as lean meats, fish, and poultry.
Reduce your intake of sugary foods in order to control your blood sugar levels.
Include leafy greens and cruciferous vegetables in your diet to improve liver health.
Avoid alcohol consumption.
Engage in moderate exercise to maintain strength and reduce fatigue.
Get adequate sleep and rest.
Practice proper hygiene and prevent contact with sick persons.
Try relaxation techniques such as meditation or deep breathing.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Alcohol

Caution

Avoid or limit alcohol consumption while on treatment with Lagipeg Injection 5 ml as it may worsen your condition.

Pregnancy

Caution

If you are pregnant or planning pregnancy, inform your doctor before receiving Lagipeg Injection 5 ml. Your doctor will prescribe this medicine only if clearly needed.

Breast Feeding

Caution

It is not known if Peg-L-Asparaginase passes into breast milk. Please consult the doctor if you are breastfeeding. Your doctor will advise you to discontinue breastfeeding or the medicine based on your condition.

Driving

Caution

Lagipeg Injection 5 ml may cause drowsiness or dizziness. If you experience any such side effects, avoid driving or operating machinery.

Liver

Caution

If you have pre-existing or a history of liver disease, inform your doctor before receiving Lagipeg Injection 5 ml. Your doctor may recommend regular tests to monitor liver function while receiving Lagipeg Injection 5 ml.

Kidney

Caution

If you have pre-existing or a history of kidney disease, inform your doctor before receiving Lagipeg Injection 5 ml. Your doctor may recommend regular tests to monitor kidney function while receiving Lagipeg Injection 5 ml.

Children

Safe if prescribed

The dosage for children is recommended based on their age, body weight, and the child's condition.

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Country of origin

India

Manufacturer/Marketer address

D' Block, 3Rd Floor, Gillander House, Netaji Subhas Road, Kolkata - 700001 (Wb)

Other Info - LAG0020

Keep Refrigerated. Do not freeze.

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FAQs

What is the use of Lagipeg Injection 5 ml?

How does Lagipeg Injection 5 ml work?

Does Lagipeg Injection 5 ml cause glucose intolerance?

How is Lagipeg Injection 5 ml administered?

Does Lagipeg Injection 5 ml cause stomach pain?

Can I drive after receiving Lagipeg Injection 5 ml?

Who should not receive Lagipeg Injection 5 ml?

What should I do if I have a history of liver complications?

Can Lagipeg Injection 5 ml be given to children?

What should I avoid during my treatment with Lagipeg Injection 5 ml?

What are the side effects of Lagipeg Injection 5 ml?

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