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  3. Kronuz 100 mg Capsule 5's

Kronuz 100 mg Capsule 5's, Pack of 5
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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Kronuz 100 mg Capsule 5's is used to treat fungal infections such as invasive aspergillosis and mucormycosis. It contains Isavuconazole which works by killing or inhibiting the growth of the fungus. In some cases, this medicine may cause side effects such as headache, decreased appetite, drowsiness, nausea, vomiting, stomach pain, diarrhoea or chest pain. Before taking this medicine, inform the doctor if you are pregnant or breastfeeding, taking any other medication, or have any pre-existing medical conditions.
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Composition :

ISAVUCONAZOLE-100MG

Manufacturer/Marketer :

AAA Pharma Trade Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Kronuz 100 mg Capsule 5's

Kronuz 100 mg Capsule 5's belongs to the class of medicines called antifungals used to treat fungal infections such as invasive aspergillosis and mucormycosis. Invasive aspergillosis is an infection caused by Aspergillus fungus. It occurs when the infection spreads from lungs to kidneys, brain, heart or skin. Mucormycosis is a rare but serious fungal infection of the skin or respiratory system that occurs in people with weakened immune systems.

Kronuz 100 mg Capsule 5's contains Isavuconazole (antifungal) that works by inhibiting the synthesis of fungal cell membranes, which are essential for their survival. Thereby, Kronuz 100 mg Capsule 5's kills or inhibits the growth of the fungus.

Take Kronuz 100 mg Capsule 5's as prescribed by your doctor. You are advised to take Kronuz 100 mg Capsule 5's for as long as your doctor has prescribed it for you based on your medical condition. Some people may experience headache, decreased appetite, drowsiness, nausea, vomiting, stomach pain, diarrhoea or chest pain. Most of these side effects of Kronuz 100 mg Capsule 5's do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to Kronuz 100 mg Capsule 5's or any other medicines, please tell your doctor. Kronuz 100 mg Capsule 5's is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Kronuz 100 mg Capsule 5's. Avoid breastfeeding while taking Kronuz 100 mg Capsule 5's. Drive only if you are alert after taking Kronuz 100 mg Capsule 5's as it may cause drowsiness, confusion or tiredness. Avoid alcohol consumption while taking Kronuz 100 mg Capsule 5's as it may increase the risk of liver damage.

Uses of Kronuz 100 mg Capsule 5's

Treatment of Invasive aspergillosis and Mucormycosis

Directions for Use

• Kronuz 100 mg Capsule 5's can be taken with or without food.• It is recommended to take Kronuz 100 mg Capsule 5's 3 times a day on the first two days, then once daily afterward, or as advised by your doctor.• Swallow Kronuz 100 mg Capsule 5's as a whole with a glass of water.• Do not crush, chew, or open it.

Medicinal Benefits

Kronuz 100 mg Capsule 5's contains Isavuconazole, a broad-spectrum antifungal that is effective against a wide variety of microorganisms. It inhibits the synthesis of fungal cell membranes that are essential for their survival. Thereby, Kronuz 100 mg Capsule 5's kills or stops the growth of the fungus.

How Kronuz 100 mg Capsule 5's Works

Kronuz 100 mg Capsule 5's contains Isavuconazole (antifungal) that works by inhibiting the synthesis of fungal cell membranes, which are essential for their survival. Thereby, Kronuz 100 mg Capsule 5's kills or inhibits the growth of the fungus.

Storage

Keep Kronuz 100 mg Capsule 5's out of the sight and reach of children.
Side effects of Kronuz 100 mg Capsule
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.

What if I have taken an overdose of Kronuz 100 mg Capsule 5's

Take Kronuz 100 mg Capsule 5's only as prescribed by the physician. Avoid exceeding the recommended dose as it could lead to an overdose. Symptoms of overdose may include dizziness, headache, paraesthesia (pins and needles sensation), sleepiness, dry mouth, diarrhoea, dysgeusia (altered taste), disturbance in attention, vomiting, hot flushes, restlessness, anxiety, oral hypoaesthesia (reduced sensitivity), palpitations, photophobia (fear of light), tachycardia (fast heart rate), and arthralgia (joint pain). If you experience these symptoms or suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

If you are allergic to Kronuz 100 mg Capsule 5's or any other medicines, please tell your doctor. Kronuz 100 mg Capsule 5's is not recommended for children below 18 years as the safety and effectiveness were not established. If you are pregnant, it is advised to consult a doctor before using Kronuz 100 mg Capsule 5's. Avoid breastfeeding while taking Kronuz 100 mg Capsule 5's. Drive only if you are alert after taking Kronuz 100 mg Capsule 5's as it may cause drowsiness, confusion or tiredness. Avoid alcohol consumption while taking Kronuz 100 mg Capsule 5's as it may increase the risk of liver damage. If you experience severe blistering of the eyes, mouth, skin or genitals, seek immediate medical help.

Drug-Drug Interactions

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IsavuconazoleRitonavir
Critical
IsavuconazoleItraconazole
Critical

Drug-Drug Interactions

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IsavuconazoleRitonavir
Critical
How does the drug interact with Kronuz 100 mg Capsule:
Taking Kronuz 100 mg Capsule with Ritonavir may significantly increase the blood levels of Kronuz 100 mg Capsule, which may increase the risk of side effects.

How to manage the interaction:
Taking Kronuz 100 mg Capsule with Ritonavir is not recommended as it can possibly result in an interaction, it can be taken if a doctor has advised it. If you notice any of these symptoms like nausea, vomiting, loose stools, light color stools or dark urine, consult a doctor. Do not discontinue any medications without consulting a doctor.
IsavuconazoleItraconazole
Critical
How does the drug interact with Kronuz 100 mg Capsule:
The blood levels and effects of Kronuz 100 mg Capsule may be significantly enhanced by taking Itraconazole along with it.

How to manage the interaction:
Co-administration of Kronuz 100 mg Capsule and Itraconazole can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazolePosaconazole
Critical
How does the drug interact with Kronuz 100 mg Capsule:
When Kronuz 100 mg Capsule is taken with Posaconazole, it can increase the levels of Kronuz 100 mg Capsule in the blood.

How to manage the interaction:
Although there is an interaction between Kronuz 100 mg Capsule and posaconazole, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
IsavuconazolePhenytoin
Critical
How does the drug interact with Kronuz 100 mg Capsule:
Co-administration of phenytoin and Kronuz 100 mg Capsule may significantly reduce the blood levels of Kronuz 100 mg Capsule, which may make Kronuz 100 mg Capsule less effective in treating your condition.

How to manage the interaction:
Taking Kronuz 100 mg Capsule with Phenytoin is not recommended as it can cause an interaction, consult a doctor before taking it. Do not discontinue any medication without consulting a doctor.
IsavuconazoleSaquinavir
Critical
How does the drug interact with Kronuz 100 mg Capsule:
When Kronuz 100 mg Capsule is taken with Saquinavir, it can increase the risk of liver damage.

How to manage the interaction:
Taking Kronuz 100 mg Capsule with Saquinavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, vomiting, diarrhea while on therapy with these drugs, consult the doctor.
IsavuconazoleFosamprenavir
Critical
How does the drug interact with Kronuz 100 mg Capsule:
When Fosamprenavir is taken with Kronuz 100 mg Capsule, it can increase the risk of side effects like liver damage.

How to manage the interaction:
Taking Kronuz 100 mg Capsule with Fosamprenavir is not recommended, it can be taken if prescribed by the doctor. However, if you experience nausea, vomiting, diarrhea while on therapy with these drugs, consult the doctor.
IsavuconazoleClarithromycin
Critical
How does the drug interact with Kronuz 100 mg Capsule:
When Kronuz 100 mg Capsule is taken with Clarithromycin, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Clarithromycin and Kronuz 100 mg Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazoleKetoconazole
Critical
How does the drug interact with Kronuz 100 mg Capsule:
Co-administration of Ketoconazole and Kronuz 100 mg Capsule can significantly increase the blood levels of Kronuz 100 mg Capsule, which may increase the risk of side effects.

How to manage the interaction:
Taking Kronuz 100 mg Capsule with Ketoconazole is not recommended as it can cause an interaction, it can be taken if prescribed by the doctor. However, if you experience symptoms like nausea, stomach pain, headache while on therapy with these drugs, consult the doctor. Do not discontinue any medication without consulting a doctor.
IsavuconazoleCeritinib
Critical
How does the drug interact with Kronuz 100 mg Capsule:
Taking ceritinib with Kronuz 100 mg Capsule may significantly increase the blood levels of Kronuz 100 mg Capsule.

How to manage the interaction:
Taking Kronuz 100 mg Capsule with Ceritinib is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loose stools, yellow discoloration of skin and eyes, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
IsavuconazolePhenobarbital
Critical
How does the drug interact with Kronuz 100 mg Capsule:
When Kronuz 100 mg Capsule is taken with Phenobarbital, may decrease the blood levels of Kronuz 100 mg Capsule, which may make Kronuz 100 mg Capsule less effective.

How to manage the interaction:
Taking Kronuz 100 mg Capsule with Phenobarbital is not recommended it can be taken if prescribed by the doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ISAVUCONAZOLE-100MGGrapefruit and Grapefruit Juice

Drug-Food Interactions

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ISAVUCONAZOLE-100MGGrapefruit and Grapefruit Juice
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Taking grapefruit and grapefruit juice during Kronuz 100 mg Capsule treatment may cause an interaction. Avoid grapefruit products during treatment with Kronuz 100 mg Capsule

Diet & Lifestyle Advise

  • Try to avoid areas with a lot of dust like excavation or construction sites. If you can’t avoid it, wear an N95 mask while going to such places.
  • Clean skin injuries with soap and water, especially if they have been exposed to dust or soil to decrease the chances of developing a skin infection.
  • Bandage all wounds until they heal to prevent fungal infections.
  • Wash your hands regularly and keep your hands clean to prevent the spread of germs.
  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt, long pants and a mask while doing outdoor activities such as yard work, gardening or vising wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Kronuz 100 mg Capsule 5's Substitute

Substitutes safety advice

Product Substitutes

bannner image

Alcohol

Unsafe

Avoid consumption of alcohol while taking Kronuz 100 mg Capsule 5's as it may increase the risk of liver damage.

bannner image

Pregnancy

Caution

Kronuz 100 mg Capsule 5's is given to a pregnant woman if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant or planning for pregnancy.

bannner image

Breast Feeding

Unsafe

Avoid breastfeeding while taking Kronuz 100 mg Capsule 5's. Please consult a doctor if you are breastfeeding.

bannner image

Driving

Caution

Drive only if you are alert after taking Kronuz 100 mg Capsule 5's as it may cause drowsiness, confusion or tiredness.

bannner image

Liver

Caution

Kronuz 100 mg Capsule 5's should be given with caution, especially if you have a history of Liver diseases/conditions.

bannner image

Kidney

Caution

Kronuz 100 mg Capsule 5's should be given with caution, especially if you have a history of Kidney diseases/conditions.

bannner image

Children

Unsafe

Kronuz 100 mg Capsule 5's is not recommended for children below 18 years as the safety and effectiveness were not established.

Have a query?

FAQs

Kronuz 100 mg Capsule 5's is used to treat fungal infections such as invasive aspergillosis and mucormycosis.

Kronuz 100 mg Capsule 5's contains Isavuconazole that works by inhibiting the synthesis of fungal cell membranes which are essential for their survival. Thereby, Kronuz 100 mg Capsule 5's kills or inhibits the growth of the fungus.

Mucormycosis is not contagious. Mucormycosis is a severe fungal infection of the skin or respiratory system that occurs in people with weakened immune system.

Kronuz 100 mg Capsule 5's may cause headache as a common side effect. However, if the condition persists or worsen, please consult a doctor.

You are not recommended to take Kronuz 100 mg Capsule 5's with ketoconazole as it may increase the levels of Kronuz 100 mg Capsule 5's in blood and increase the risk of side effects such as diarrhoea, vomiting, nausea or liver problems. However, please consult your doctor before taking Kronuz 100 mg Capsule 5's with other medicines.

You are not recommended to stop using Kronuz 100 mg Capsule 5's without consulting your doctor as it may worsen the condition or cause a recurring infection. Therefore, use Kronuz 100 mg Capsule 5's for as long as your doctor has prescribed it and if you experience any difficulty while taking Kronuz 100 mg Capsule 5's, please consult your doctor.

Kronuz 100 mg Capsule 5's belongs to the class of medicines called antifungals used to treat fungal infections such as invasive aspergillosis and mucormycosis.

Inform your doctor about your medical history, current medications, allergies, and if you're pregnant or breastfeeding before starting treatment with Kronuz 100 mg Capsule 5's.

Kronuz 100 mg Capsule 5's should not be used in people who are allergic to any of its components and children below 18 years as the safety and effectiveness were not established.

If you miss a dose of Kronuz 100 mg Capsule 5's, take it as soon as you remember. However, if it's close to the next dose, skip the missed dose and continue with your regular schedule.

Kronuz 100 mg Capsule 5's is safe when used as prescribed by your doctor. However, it may cause side effects like headache, decreased appetite, drowsiness, nausea, vomiting, stomach pain, and chest pain while using it.

The common side effects of Kronuz 100 mg Capsule 5's may include headache, decreased appetite, drowsiness, nausea, vomiting, stomach pain, diarrhoea or chest pain. Most of these side effects of Kronuz 100 mg Capsule 5's do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

Country of origin

India

Manufacturer/Marketer address

E-11, Moti Nagar , New Delhi-110015
Other Info - KRO0057

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 18, 2025 | 6:53 AM IST

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Reference

  1. https://www.medicines.org.uk/emc/files/pil.5071.pdf
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