apollo
logo
0
Select Delivery Location
prescriptionPrescription Medicine
Kolibitor 10ml Injection is used to treat bacterial infections. It contains Sulfamethoxazole (sulfonamide) and Trimethoprim (antifolate). These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thus, it inhibits the growth and multiplication of bacteria and stops the spread of infection. Common side effects of Kolibitor 10ml Injection may include abnormal heartbeats, headache, diarrhoea, skin rashes, nausea, thrush or candidiasis (a fungal infection that affects the mouth or vagina).
Read more
Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
OffersOffers & Discounts

Get Free delivery (₹99) with circle icon

Join Circle
coupon
Get Extra 18% Off with Coupons
coupon
coupon
coupon
Extra 10% Off with Bank Offers

More about the Product

Manufacturer/Marketer :

Fusion Health Care Pvt Ltd

Consume Type :

Parenteral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Kolibitor 10ml Injection

Kolibitor 10ml Injection belongs to the class of medicines called antibiotics. It is used to treat or prevent lung infections caused by bacteria called Pneumocystis jirovecii and Toxoplasma. Also, it is used to treat urinary bladder or urinary tract infections (water infections), ear infections such as otitis media, respiratory tract infections such as bronchitis, and nocardiosis, which can affect the skin, lungs and brain. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly. Kolibitor 10ml Injection does not work against infections, flu or cold symptoms caused by the virus.

Kolibitor 10ml Injection contains two antibiotics, Sulfamethoxazole (sulfonamide) and Trimethoprim (antifolate). These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thus, it inhibits the growth and multiplication of bacteria and stops the spread of infection.

Kolibitor 10ml Injection will be administered by a healthcare professional; do not self-administer. Sometimes, you may experience abnormal heartbeats, headache, diarrhoea, skin rashes, nausea, thrush or candidiasis (a fungal infection that affects the mouth or vagina) as side effects. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid receiving Kolibitor 10ml Injection if you are allergic to Sulfamethoxazole, trimethoprim, co-trimoxazole, or any other ingredients of Kolibitor 10ml Injection, or sulfonamide medicines or if you have thrombocytopenia (low blood platelets), porphyria (a rare blood problem), severe liver or kidney problems. $nmae is not recommended for infants aged six weeks. If you are pregnant or planning for pregnancy, inform your doctor before receiving Kolibitor 10ml Injection. You are recommended to avoid breastfeeding while on treatment with Kolibitor 10ml Injection. If you have reddish target-like spots or circular patches, often with central blisters on the trunk, please consult a doctor immediately, as these might be signs of Stevens-Johnson syndrome.

Uses of Kolibitor 10ml Injection

Kolibitor 10ml Injection is used in the treatment of Bacterial infections. The detailed uses of Kolibitor 10ml Injection are as follows:

  • Treat a wide range of bacterial infections: Kolibitor 10ml Injection is used to manage infections of the urinary tract, respiratory tract (such as bronchitis and pneumonia), gastrointestinal tract (like shigellosis and traveler’s diarrhea), and middle ear (otitis media) by inhibiting bacterial folic acid synthesis.
  • Prevent and treat Pneumocystis jirovecii pneumonia (PCP): Kolibitor 10ml Injection is commonly used in immunocompromised patients, such as those with HIV/AIDS, to prevent or treat this serious fungal-like lung infection.

Key Benefits

Kolibitor 10ml Injection is a combination of two antibiotics, Sulfamethoxazole and Trimethoprim. It is used to treat or prevent lung infections caused by a bacteria called Pneumocystis jirovecii and infections caused by a bacteria called Toxoplasma. Also, it is used to treat urinary bladder or urinary tract infections (water infections), respiratory tract infections such as bronchitis, ear infections such as otitis media, and nocardiosis which can affect the skin, lungs and brain. Additionally, Kolibitor 10ml Injection is used to treat brucellosis (a bacterial infection that spreads from animals to people) if other treatments are not effective and in combination with other agents in line with national treatment guidelines. These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thereby inhibiting the growth and multiplication of bacteria and stopping the spread of infection.

Directions for Use

  • Your doctor will determine the dosage and frequency depending on your condition.
  • Kolibitor 10ml Injection will be administered by a healthcare professional.
  • Do not self-administer.

How Kolibitor 10ml Injection Works

Kolibitor 10ml Injection contains two antibiotics, Sulfamethoxazole (sulfonamide) and Trimethoprim (antifolate). These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thus, it inhibits the growth and multiplication of bacteria and stops the spread of infection.
bannner image

Alcohol

Consult your doctor

The interaction of Kolibitor 10ml Injection with alcohol is unknown. If you have any concerns, please discuss them with your doctor.

bannner image

Pregnancy

Consult your doctor

Kolibitor 10ml Injection may harm the foetus. Therefore, if you are pregnant or planning pregnancy, inform your doctor before receiving Kolibitor 10ml Injection. Your doctor may prescribe this medicine if the benefits outweigh the risks.

bannner image

Breast Feeding

Caution

Avoid breastfeeding while on treatment with Kolibitor 10ml Injection due to its potential risk of bilirubin displacement and kernicterus (brain damage). If you are a breastfeeding mother, please inform your doctor before receiving Kolibitor 10ml Injection.

bannner image

Driving

Consult your doctor

Limited information is available on the effect of Kolibitor 10ml Injection on driving. Please discuss with your doctor before driving or operating machinery after receiving Kolibitor 10ml Injection.

bannner image

Liver

Consult your doctor

If you have a pre-existing or a history of liver disease, inform your doctor before receiving Kolibitor 10ml Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Kolibitor 10ml Injection is contraindicated in patients with severe liver disease.

bannner image

Kidney

Consult your doctor

If you have a pre-existing or a history of kidney diseases, inform your doctor before receiving Kolibitor 10ml Injection. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition. Kolibitor 10ml Injection is contraindicated in patients with severe kidney disease.

bannner image

Children

Caution

Kolibitor 10ml Injection is contraindicated in children less than two months of age (less than six weeks) due to the risk of bilirubin displacement and kernicterus (brain damage).

bannner image

Heart

Caution

Inform your doctor before receiving Kolibitor 10ml Injection if you have a pre-existing or a history of heart disease. Your doctor will prescribe only if the benefits outweigh the risks.

bannner image

Geriatrics

Caution

Kolibitor 10ml Injection should be used in the elderly only if advised by a doctor, as dose adjustment may be required.

What if I have taken an overdose of Kolibitor 10ml Injection

As Kolibitor 10ml Injection is a parenteral formulation administered by experienced medical staff, the chance of overdose may be less. However, if you think there has been an overdose or experiencing any adverse events, get medical care right away. Overdose of Kolibitor 10ml Injection may cause nausea/vomiting, dizziness, headache, mental depression, confusion, thrombocytopenia, uremia, and loss of appetite.

Diet & Lifestyle Advise

  • Take probiotics after completing the full course of Kolibitor 10ml Injection to restore some healthy bacteria in the intestines that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like cheese, yoghurt, kombucha, sauerkraut, and kimchi can restore the good bacteria of the intestine.
  • Include fibre-rich foods, as they can be easily digested by your gut bacteria, which helps stimulate their growth. Thus, fibre-rich foods may help restore healthy gut bacteria after a course of antibiotics. Whole grains such as brown rice and whole-grain bread should be included in your diet.
  • Make sure you drink plenty of water or other fluids daily while taking Kolibitor 10ml Injection.
  • Avoid alcohol consumption as it may increase adverse effects.

Have a query?

How Soon It Starts Working

The time required for Kolibitor 10ml Injection to start to work: The time required for Kolibitor 10ml Injection to show its action is not clinically established. The time for which the effects of Kolibitor 10ml Injection last: The duration of action for Kolibitor 10ml Injection is not clinically established.

What if you forget to take Kolibitor 10ml Injection

As this medicine will be administered by a healthcare professional, the chances of missing a dose are less. However, consult your doctor if you have any concerns.

Storage

• Store in a cool and dry place away from sunlight. • Keep Kolibitor 10ml Injection out of sight and reach of children. • Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

Drug Warnings

Avoid receiving Kolibitor 10ml Injection if you are allergic to Sulfamethoxazole, trimethoprim, co-trimoxazole, or any other ingredients of Kolibitor 10ml Injection, or sulfonamide medicines or if you have thrombocytopenia (low blood platelets), porphyria (a rare blood problem), severe liver or kidney problems. $nmae is not recommended for infants aged six weeks. If you are pregnant or planning for pregnancy, inform your doctor before receiving Kolibitor 10ml Injection. You are recommended to avoid breastfeeding while on treatment with Kolibitor 10ml Injection. If you have reddish target-like spots or circular patches, often with central blisters on the trunk, please consult a doctor immediately, as these might be signs of Stevens-Johnson syndrome. If you are elderly, malnourished or underweight, inform your doctor before receiving Kolibitor 10ml Injection.

Drug-Drug Interactions

verifiedApollotooltip

Drug-Drug Interactions: Inform your doctor if you are taking antiviral and antiparkinson agents (amantadine), immunosuppressants (ciclosporin, azathioprine), anticancer drugs (methotrexate), antiparasitics (pyrimethamine), diuretic (spironolactone), a blood thinner (warfarin), anticonvulsant (phenytoin), antidiabetics (glibenclamide, tolbutamide, glipizide, repaglinide), medicines used to treat heart problems (digoxin, procainamide), anti-HIV drugs (lamivudine, zidovudine), steroid (prednisolone), antibiotic (rifampicin), folinic acid and contraceptives. 

Drug-Food interactions: No interactions found.

Drug-Disease Interactions: Avoid receiving Kolibitor 10ml Injection if you have thrombocytopenia (low blood platelets), porphyria (a rare blood problem), or severe liver or kidney problems. If you have bronchial asthma or severe allergies, porphyria (rare blood disorder), anaemia (lack of blood), glucose-6-phosphate dehydrogenase deficiency, phenylketonuria (build-up of an amino acid called phenylalanine in the body), malnourished or underweight, haematological disorders (serious blood disorders), kidney disease, high levels of potassium and abnormally low levels of sodium in the blood, inform your doctor before receiving Kolibitor 10ml Injection.

Drug-Drug Interactions

Login/Sign Up

How does the drug interact with Kolibitor Injection 10 ml:
Using trimethoprim and sulfamethoxazole with BCG vaccine can reduce the effect of BCG vaccine

How to manage the interaction:
Taking Trimethoprim and sulfamethoxazole with BCG vaccine may lead to an interaction, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms consult a doctor. Do not stop using any medications without a doctor's advice.
How does the drug interact with Kolibitor Injection 10 ml:
Taking Losartan with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Losartan with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kolibitor Injection 10 ml:
Taking Bupivacaine with Trimethoprim and sulfamethoxazole can lead to increased risk of side effects.

How to manage the interaction:
Although taking Bupivacaine with sulfamethoxazole and trimethoprim may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience gray coloured skin, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, difficulty in breathing, increased heartrate, anxiety or confusion . Do not stop using any medications without talking to a doctor.
How does the drug interact with Kolibitor Injection 10 ml:
Taking Clozapine with Trimethoprim and sulfamethoxazole can lead to increased risk of infections.

How to manage the interaction:
Although taking Clozapine with trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience fever, chills, loose stools, muscle pains, shortness or breath, blood in cough fluid, body sores or difficulty while passing urine . Do not stop using any medications without talking to a doctor.
How does the drug interact with Kolibitor Injection 10 ml:
Taking Irbesartan with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Irbesartan with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kolibitor Injection 10 ml:
Taking phenytoin with Trimethoprim and sulfamethoxazole can increase the blood levels of Fosphenytoin.

How to manage the interaction:
Although taking phenytoin with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience symptoms like nausea, vomiting, unintentional eye movements, blurred eyesight, difficulty in speaking, loss of body balance, shaking of hands or legs, or confusion. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kolibitor Injection 10 ml:
Taking Tetracaine with Trimethoprim and sulfamethoxazole can lead to increased risk of side effects.

How to manage the interaction:
Although taking Tetracaine with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience gray coloured skin, nausea, headache, dizziness, lightheadedness, tiredness, shortness of breath, difficulty in breathing, increased heartrate, anxiety or confusion . Do not stop using any medications without talking to a doctor.
How does the drug interact with Kolibitor Injection 10 ml:
Taking Benazepril with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Benazepril with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kolibitor Injection 10 ml:
Taking Potassium chloride with Trimethoprim and sulfamethoxazole can lead to increased potassium salt in blood.

How to manage the interaction:
Although taking Potassium chloride with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in hands or feet, feeling of heaviness in the legs, or slow or rapid heartbeat. Do not stop using any medications without talking to a doctor.
How does the drug interact with Kolibitor Injection 10 ml:
Taking Methotrexate with Trimethoprim and sulfamethoxazole can lead to increased risk of infections.

How to manage the interaction:
Although taking Methotrexate with Trimethoprim and sulfamethoxazole may lead to an interaction, it can be taken if prescribed by a doctor. However, consult the doctor if you experience fever, chills, loose stools, muscle pains, shortness or breath, blood in cough fluid, body sores or difficulty while passing urine . Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

verifiedApollotooltip
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

Login/Sign Up

All Substitutes & Brand Comparisons

Habit Forming

No

Therapeutic Class

[ANTIBIOTIC COMBINATION]

FAQs

Kolibitor 10ml Injection is used to treat Bacterial infections.

Kolibitor 10ml Injection is a combination of two antibiotics, Trimethoprim and Sulfamethoxazole. These antibiotics work together to prevent bacteria from producing folic acid, which is necessary for DNA production. Thereby inhibiting the growth and multiplication of bacteria, it stops the spread of infection.

Kolibitor 10ml Injection may cause diarrhoea as a common side effect. Drink plenty of fluids and eat fibre-rich food if you experience diarrhoea. However, if the condition persists or worsens, or if you notice blood or mucus in your stools, inform your doctor immediately.

Kolibitor 10ml Injection is not used to treat viral infections. Kolibitor 10ml Injection is a combination of antibiotics that is used to treat only bacterial infections. If you have a viral infection, please consult a doctor so that appropriate medication may be prescribed.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Author Details

Doctor imageWe provide you with authentic, trustworthy and relevant information

Country of origin

India

Manufacturer/Marketer address

Fusion House, Plot No. 22, H.No 8-2-350/B, Road No. 3, Banjara Hills, Hyderabad, Telangana-500034
Other Info - KOL0115
whatsapp Floating Button
Buy Now
Add to Cart