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  3. Kezan Tablet 10's

Kezan Tablet 10's, Pack of 10
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Written By ,
Reviewed By Santoshini Reddy G , M Pharmacy

Kezan Tablet 10's is used to treat reflux esophagitis, gastric ulcers, and duodenal ulcers. It also helps prevent the recurrence of gastric or duodenal ulcers during the use of low-dose aspirin or NSAIDs. It works by reducing the amount of acid produced in the stomach. Common side effects may include diarrhoea, bloating, stomach pain, nausea, and indigestion. Before starting Kezan Tablet 10's, let the doctor know if you are pregnant, breastfeeding, taking other medicines or have pre-existing medical conditions.

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Composition :

VONOPRAZAN-20MG

Manufacturer/Marketer :

San Fegan Biotech Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Kezan Tablet 10's

Kezan Tablet 10's belongs to the group of medications known as potassium-competitive acid blockers (PCAB), primarily used to treat gastrointestinal disorders such as reflux esophagitis, gastric ulcers, and duodenal ulcers. It is also used to treat Helicobacter pylori infection in combination with clarithromycin and/or amoxicillin. Reflux esophagitis occurs when stomach acid irritates the esophagus, often due to GERD. Gastric ulcers are sores on the stomach lining, commonly caused by H. pylori or NSAIDs. Duodenal ulcers form in the small intestine, typically caused by H. pylori or excess stomach acid.

Kezan Tablet 10's contains Vonoprazan. It works by inhibiting the H+, K+-ATPase enzyme in the stomach's parietal cells, which reduces the amount of acid produced in the stomach. This enzyme is responsible for pumping acid into the stomach. Unlike other inhibitors, it doesn't require acid activation and can selectively target parietal cells, binding to the active pumps reversibly.

Take Kezan Tablet 10's for the duration prescribed by your doctor based on your medical condition. Some common side effects may include diarrhoea, bloating, stomach pain, nausea, and indigestion. These effects are usually temporary and do not require medical attention. However, if they continue or worsen, see your doctor for advice.

It is advisable not to take Kezan Tablet 10's if you are allergic to any of its ingredients. If you are pregnant or breastfeeding, make sure to consult your doctor before using Kezan Tablet 10's. Inform your doctor if you have or have had kidney or liver disorders, osteopenia (a condition causing bone mass loss), osteoporosis (a condition that weakens bones, making them brittle and prone to fractures), or low levels of calcium, magnesium, or potassium in your blood. The safety and effectiveness of Kezan Tablet 10's have not been established in children.

Uses of Kezan Tablet 10's

Kezan Tablet 10's is used in the treatment of reflux esophagitis, ulcers and Helicobacter pylori Infection, to prevent the recurrence of gastric or duodenal ulcers. The detailed uses of Kezan Tablet 10's are as follows:

  • Treatment of Esophagitis: Kezan Tablet 10's helps heal damage to the oesophagus caused by stomach acid and reduces symptoms like heartburn and acid reflux.
  • Helicobacter Pylori (H. Pylori) Infection: Kezan Tablet 10's is used in combination with antibiotics to eliminate H. pylori bacteria, which can cause stomach ulcers and helps prevent recurrence of ulcers and gastritis.
  • Healing Stomach Ulcers: Kezan Tablet 10's Reduces excess stomach acid, allowing ulcers to heal faster. Protects the stomach lining from further damage.
  • Prevention of Ulcer Recurrence: Kezan Tablet 10's helps prevent ulcers from coming back, especially in individuals prone to acid-related issues, and is often prescribed for long-term acid suppression therapy.

Directions for Use

  • Kezan Tablet 10's can be taken with or without food or as advised by your doctor.
  • Kezan Tablet 10's is usually taken twice a day, or as prescribed by your doctor.
  • Swallow Kezan Tablet 10's as a whole with a glass of water.
  • Do not break, crush or chew it.

Medicinal Benefits

Kezan Tablet 10's offers several advantages over traditional proton pump inhibitors (PPIs). It has a faster onset of action, providing quicker relief for acid-related discomfort. Compared to traditional PPIs, it doesn't require stomach acid for activation, making it effective in all gastric conditions. Its effects are not influenced by meals, allowing flexible timing. Kezan Tablet 10's provides stronger and more sustained suppression of gastric acid secretion, ensuring potent inhibition. Additionally, it remains stable in the stomach, delivering long-lasting effects.

How Kezan Tablet 10's Works

Kezan Tablet 10's contains Vonoprazan. It works by inhibiting the H+, K+-ATPase enzyme in the stomach's parietal cells, which reduces the amount of acid produced in the stomach. Thereby, Kezan Tablet 10's helps treat reflux esophagitis, gastric ulcers, duodenal ulcers, and Helicobacter pylori infection.

Storage

• Store in a cool and dry place away from sunlight.• Keep Kezan Tablet 10's out of the sight and reach of children.• Non cold chain - To be stored in cool places at 10ºC to 25ºC or below 30ºC.

What if I have taken an overdose of Kezan Tablet 10's

Take Kezan Tablet 10's only as advised by the physician. Do not exceed the prescribed dose, as it might cause an overdose. If you suspect you have taken an overdose, seek immediate medical attention.

Drug Warnings

Inform your doctor if you are allergic to any of the ingredients in Kezan Tablet 10's or any other medications. If you are pregnant or breastfeeding, consult your doctor for advice. Avoid alcohol consumption while taking Kezan Tablet 10's. Inform your doctor about any other medications or herbal supplements you are using before starting Kezan Tablet 10's. Let your doctor know if you have a history of gastric malignancy, acute tubulointerstitial nephritis, or Clostridioides difficile-associated diarrhea, osteopenia, severe skin reactions, vitamin B12 deficiency, or hypomagnesemia.

Diet & Lifestyle Advise

  • Eat foods that are rich in probiotics, such as yoghurt/curd, natto, and cheese.
  • Try to add fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas, and bananas to your daily diet, which helps aid digestion.
  • Eat smaller, more frequent meals rather than larger ones.
  • Avoid processed, deep-fried foods as they are hard to digest.
  • Avoid alcohol and smoking as they increase acid production.
  • Engage in light physical activity to aid digestion.

Habit Forming

No

Therapeutic Class

GASTROINTESTINAL AGENTS

Kezan Tablet 10's Substitute

Substitutes safety advice

Product Substitutes

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Alcohol

Caution

Avoid alcohol while taking Kezan Tablet 10's because alcohol can irritate the stomach lining, increase acid production, and worsen symptoms like heartburn or indigestion.

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Pregnancy

Caution

If you are pregnant or planning a pregnancy, inform the doctor before receiving Kezan Tablet 10's. Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Caution

It is not known if vonoprazan passes into breast milk. Consult your healthcare provider to assess risks and benefits.

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Driving

Caution

It is unknown if Kezan Tablet 10's affects your ability to drive. Consult your healthcare provider to assess risks and benefits.

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Liver

Caution

Inform your doctor if you have liver impairment. Your doctor will weigh the benefits and any potential risks before prescribing.

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Kidney

Caution

Inform your doctor if you have kidney impairment. Your doctor will weigh the benefits and any potential risks before prescribing.

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Children

Caution

The safety and effectiveness of Kezan Tablet 10's have not been established in children. If you have any concerns regarding the use of Kezan Tablet 10's for children, please consult a doctor.

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Heart

Please consult your doctor if you have any pre-existing heart problems before using Kezan Tablet 10's. Your doctor will prescribe Kezan Tablet 10's if the benefits outweigh the risk.

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Geriatrics

Consult your doctor

Limited information is available on the use of Kezan Tablet 10's in elderly patients. Please consult a doctor if you have any concerns about its use in elderly patients.

Have a query?

FAQs

Kezan Tablet 10's is used for the treatment of reflux esophagitis, gastric ulcer, and duodenal ulcer. It also helps prevent the recurrence of gastric or duodenal ulcers during the use of low-dose aspirin or NSAIDs. Besides this, Kezan Tablet 10's is used in the treatment of Helicobacter pylori infection, usually in combination with both amoxicillin and clarithromycin or with amoxicillin alone.

Kezan Tablet 10's contains Vonoprazan. It works by inhibiting the H+, K+-ATPase enzyme in the stomach's parietal cells, which reduces the amount of acid produced in the stomach. Thereby, Kezan Tablet 10's helps treat reflux esophagitis, gastric ulcers, duodenal ulcers, and Helicobacter pylori infection.

Yes, Kezan Tablet 10's can be taken with antibiotics such as amoxicillin and clarithromycin, especially for Helicobacter pylori treatment if prescribed by the doctor. Follow your doctor’s advice for proper usage and dosage.

Do not stop taking Kezan Tablet 10's without consulting your doctor, as it may reduce the medication’s effectiveness. To treat your condition effectively, continue taking Kezan Tablet 10's for as long as prescribed by your doctor. If you experience any difficulty taking Kezan Tablet 10's, do not hesitate to speak with your doctor.

Pregnant and breastfeeding women should consult their doctor before taking this medicine to ensure it is safe for both the mother and the baby. Talk to the doctor if you have any concerns.

Taking higher doses than prescribed is ineffective and may cause side effects. Therefore, it's essential to follow the dosage instructions provided by your doctor to ensure safe and effective use.

Avoid alcohol while taking Kezan Tablet 10's, as it can increase stomach acid and worsen symptoms like heartburn, acid reflux, and indigestion; it also may interfere with the medication’s effectiveness.

Avoid spicy, fatty, and acidic foods while taking Kezan Tablet 10's, as they can irritate the stomach, increase acid production, and make symptoms like heartburn and indigestion worse.

Common side effects include diarrhoea, bloating, stomach pain, nausea, and indigestion. Seek medical care if the symptoms persist or worsen.

Kezan Tablet 10's may cause serious side effects like kidney problems, C. difficile-associated diarrhoea, bone fractures, severe skin reactions, low vitamin B12 levels, low magnesium levels or fundic gland polyps (stomach growths). Consult the doctor if you experience symptoms of kidney problems (decreased urine or blood in urine), C. difficile-associated diarrhoea (watery stools, stomach pain, fever), bone fractures, severe skin reactions (skin rash, fever, chills, body aches, shortness of breath), low vitamin B12 (lightheadedness, tingling, numbness, muscle weakness, irregular heart beat, shortness of breath, tiredness, mood changes), or low magnesium (dizziness, irregular heartbeat, spasms of hands/feet, muscle weakness, seizures).

Country of origin

India

Manufacturer/Marketer address

67/1303, 2Nd Floor, South Point Hinton, Chittoor Road, Ernakulam, Kerala-682018
Other Info - KEZ0044

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Reference

  1. https://www.larenon.com/wp-content/uploads/2024/06/VONOGRESS-LBL.pdf
  2. https://www.accessdata.fda.gov/drugsatfda_docs/label/2023/215151s000lbl.pdf
  3. https://medlineplus.gov/druginfo/meds/a624006.html#:

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