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Ketriplin Cream 20 gm is a combination medicine indicated for the management of neuralgia (neuropathic pain). Neuropathic pain is a chronic progressive nerve disease which causes nerve pain due to damaged sensory nerves. Symptoms include spontaneous, untriggered pain, unpleasant feeling, shooting, burning or stabbing pain, difficulty resting or sleeping, and evoked pain (pain caused by events usually not painful).
Ketriplin Cream 20 gm is a combination of two drugs: Amitriptyline (tricyclic antidepressant) and Ketamine (anaesthesia). Amitriptyline works by increasing the serotonin and noradrenaline (natural substances) levels in the brain, thereby preventing the movement of pain signals in the brain. Ketamine is a general anaesthetic that blocks certain receptors (NMDA), thereby decreasing pain sensation. Thus, Ketriplin Cream 20 gm effectively alleviates neuropathic pain.
Depending on your medical condition, you are advised to use Ketriplin Cream 20 gm for as long as your doctor has prescribed it for you. In some cases, you may experience certain common side effects such as application site reactions such as skin dryness and itching. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Do not use Ketriplin Cream 20 gm if you are pregnant or breastfeeding unless prescribed by the doctor. To rule out any side effects/interactions, keep your doctor informed about your health condition and ongoing medications before using Ketriplin Cream 20 gm. Limited information is available regarding using Ketriplin Cream 20 gm in children, so do not use Ketriplin Cream 20 gm unless prescribed by the doctor.
Ketriplin Cream 20 gm is used in the treatment of Neuralgia (neuropathic pain). The detailed uses of Ketriplin Cream 20 gm are as follows:
Ketriplin Cream 20 gm is a combination of two drugs: amitriptyline (tricyclic antidepressant) and ketamine (anaesthesia). Amitriptyline works by increasing serotonin and noradrenaline (natural substances) levels in the brain, preventing the movement of pain signals. Ketamine is a general anaesthetic that reduces pain by blocking specific receptors (NMDA). Thus, Ketriplin Cream 20 gm effectively reduces neuropathic pain.
Caution
It is not known whether Ketriplin Cream 20 gm interacts with alcohol. However, as a precautionary measure, it is advisable to avoid consumption of alcohol.
Consult your doctor
Limited data is available on the effect of Ketriplin Cream 20 gm in pregnancy. Hence, please consult your doctor before using Ketriplin Cream 20 gm.
Consult your doctor
If you are breastfeeding, please consult your doctor before using Ketriplin Cream 20 gm.
Safe
Ketriplin Cream 20 gm does not affect your ability to drive.
Caution
Limited information is available about using Ketriplin Cream 20 gm in patients with liver disease. Inform your doctor before using Ketriplin Cream 20 gm if you have a history of liver disease. Your doctor will prescribe only if the benefits outweigh the risks.
Caution
Limited information was available about using Ketriplin Cream 20 gm in patients with kidney disease. Inform your doctor before using Ketriplin Cream 20 gm if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Consult your doctor
Limited information is available regarding using Ketriplin Cream 20 gm in children. Please consult your doctor for more information.
Consult your doctor
Please consult your doctor before taking Ketriplin Cream 20 gm if you have pre-existing heart problems.
Consult your doctor
Please consult your doctor before using Ketriplin Cream 20 gm in elderly people. Your doctor will prescribe Ketriplin Cream 20 gm if the benefits outweigh the risk.

Have a query?
Do not use Ketriplin Cream 20 gm on your own unless prescribed by the doctor. Ketriplin Cream 20 gm is not recommended to use if you are allergic to any component present in it. Ketriplin Cream 20 gm should not be used in pregnant or lactating women and the paediatric population unless prescribed by the doctor. Do not use any other medications along with Ketriplin Cream 20 gm unless instructed by the doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Drug-Drug Interactions: No interactions found/established.
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: No interactions found/established.
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Ketriplin Cream 20 gm is used to treat neuropathic pain.
Ketriplin Cream 20 gm is a combination of two drugs: amitriptyline (tricyclic antidepressant) and ketamine (anaesthesia). Amitriptyline works by increasing serotonin and noradrenaline (natural substances) levels in the brain, preventing the movement of pain signals. Ketamine is a general anaesthetic that reduces pain by blocking specific receptors (NMDA). Thus, Ketriplin Cream 20 gm effectively alleviates neuropathic pain.
Ketriplin Cream 20 gm is for topical (for skin) use only. Do not put a bandage or dressing on the affected area unless the doctor advises while treating with Ketriplin Cream 20 gm. Do not apply Ketriplin Cream 20 gm on mucous membranes, lesions, or large areas of skin. If the medicine gets into your eyes, nose or mouth, rinse thoroughly with cold water.
Store Ketriplin Cream 20 gm according to the instructions on the leaflet and away from direct sunlight. Do not freeze and dispose of unused medicine. Keep it out of reach from pets and children.
No, never take more than the prescribed dose of Ketriplin Cream 20 gm. It may lead to severe allergic reactions and symptoms like difficulty breathing, swelling of the face, neck, tongue or throat and rash. Consult your doctor if you do not observe any improvement in symptoms after a week.
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