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compositionComposition:KETOROLAC-10MG+TRAMADOL-25MG
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Prescription Medicine
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Ketotram Tablet is an analgesic medicine used to relieve moderate to severe pain and inflammation. This medicine works by blocking pain signals from being transmitted to the brain and from being perceived by the brain, thus relieves body swelling and subsequent pain. Common side effects include stomach ache, nausea, vomiting, gas, and dizziness.

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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
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More about the Product

Composition :

KETOROLAC-10MG+TRAMADOL-25MG

Manufacturer/Marketer :

Medley Pharmaceuticals Ltd

Consume Type :

Oral

Expires on or after :

Jan-27

Return Policy :

Not Returnable

About Ketotram Tablet

Ketotram Tablet is a prescription pain medication used for the short-term management of moderate to severe acute pain. It is commonly prescribed to help patients recover comfortably after surgical procedures or dental operations. This oral medication works by combining two distinct pain-relieving agents that target pain pathways in both the body and the brain.

For the best and safest results, you must take Ketotram Tablet exactly as prescribed by your doctor, usually for no more than 5 days. It is highly recommended to take this medicine with food or a glass of milk to protect your stomach from irritation. To support your recovery during treatment, ensure you get plenty of rest, stay well-hydrated, and avoid strenuous physical activities.

While taking Ketotram Tablet , you may experience common side effects such as mild dizziness, drowsiness, or an upset stomach. However, you must contact your doctor immediately if you experience serious side effects, such as severe stomach pain, black stools, difficulty breathing, or sudden skin rashes.

Before you start taking this medicine, talk to your doctor if you have a history of stomach ulcers, kidney problems, heart conditions, asthma, or a history of substance use. Do not take this if you have active stomach bleeding, severe kidney disease, or severe asthma, or if you have had an allergic reaction to aspirin or other pain relievers.

This medicine can interact dangerously with other substances; for example, taking it with blood thinners increases your risk of bleeding, while taking it with alcohol can cause dangerous sleepiness. If you are pregnant, breastfeeding, or are an elderly individual, consult your doctor before starting this medication as you may require special monitoring or alternative options.

Uses of Ketotram Tablet

Ketotram Tablet is used in the treatment of Pain. The detailed uses of Ketotram Tablet are as follows:

  • Moderate to severe acute pain: Ketotram Tablet helps by blocking pain signals in your central nervous system and reducing inflammation at the source, making severe short-term pain manageable.
  • Post-operative pain: This medication helps patients recover more comfortably immediately following surgical procedures when standard pain relievers are not strong enough.

Key Benefits

Ketotram Tablet provides rapid, dual-action pain relief by targeting pain through two different mechanisms. This helps reduce moderate to severe pain after surgery or acute injuries, allowing you to recover more comfortably and return to your daily activities sooner. Benefits may include:

  • Relieve moderate to severe pain effectively.
  • Improve comfort during recovery from surgery or injury.
  • Support better mobility and make rehabilitation exercises easier.
  • Reduce the need for higher doses of either medicine by combining two pain-relieving mechanisms.
Side effects of Ketotram Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Drink ample water throughout the day to thin mucus and keep nasal passages moist.
  • Utilize a humidifier, especially during dry seasons, to add moisture to the air.
  • Limit exposure to cigarette smoke, dust, strong odours, and other environmental pollutants.
  • Regularly use saline nasal spray to cleanse and moisturize nasal passages.
  • Practice good hand hygiene to prevent spreading germs and avoid touching your nose unnecessarily.
  • Elevate your head while sleeping to promote drainage from the sinuses.
  • Identify and avoid known allergens through allergy testing and implement measures to reduce exposure like air purifiers.
  • Inhale steam from a hot shower or bowl of water can help loosen mucus.
  • Practice relaxation techniques like yoga or meditation to manage stress which can exacerbate nasal discomfort.
  • Maintain a balanced diet rich in fruits and vegetables to support immune function.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
Here are the step-by-step strategies to manage the side effects of "indigestion" caused by medication usage:
  • Take medications with food (if recommended): It can help prevent stomach distress and indigestion.
  • Eat smaller, more frequent meals: Divide daily food intake into smaller, more frequent meals to ease digestion.
  • Avoid trigger foods: Identify and avoid foods that trigger indigestion, such as spicy, fatty, or acidic foods.
  • Stay upright after eating: Sit or stand upright for at least 1-2 hours after eating to prevent stomach acid from flowing into the oesophagus.
  • Avoid carbonated drinks: Avoid drinking carbonated beverages, such as soda or beer, which can worsen indigestion.
  • Manage stress: To alleviate indigestion, engage in stress-reducing activities like deep breathing exercises or meditation.
  • Consult a doctor if needed: If indigestion worsens or persists, consult a healthcare professional to adjust the medication regimen or explore alternative treatments.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.

Directions for Use

  • Ketotram Tablet can be taken with or without food, as advised by your doctor. However, avoid taking it with high-fat foods.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow the whole Ketotram Tablet with a glass of water.
  • Do not break, chew, or crush it.

How Ketotram Tablet Works

Ketotram Tablet combines two pain-relieving medicines namely Ketorolac and Tramadol. Ketorolac reduces pain and swelling by blocking the production of prostaglandins, the chemicals responsible for inflammation. Tramadol works on the brain and spinal cord to change how your body senses pain, helping to reduce the feeling of pain and improve comfort.
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Alcohol

Unsafe

You are advised not to take alcohol with Ketotram Tablet as it can make you dizzier. Please consult your doctor if you have any concerns.

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Pregnancy

Caution

Ketotram Tablet is not recommended for use during pregnancy unless absolutely indicated. Please consult your doctor if you have any concerns.

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Breast Feeding

Caution

Ketotram Tablet is not recommended for use during breastfeeding. Please consult your doctor if you have any concerns.

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Driving

Caution

Ketotram Tablet may cause dizziness and drowsiness, which may affect your ability to drive. Therefore, drive only if you are alert.

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Liver

Caution

Exercise caution before using Ketotram Tablet in case of established liver disease. Please consult your doctor to address any concerns.

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Kidney

Caution

Exercise caution before using Ketotram Tablet in case of kidney problems. Please consult your doctor to address any concerns.

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Children

Unsafe

Ketotram Tablet is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

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Heart

Caution

Ketotram Tablet should be taken with caution in patients with heart problems. Therefore, please talk to your doctor before using Ketotram Tablet .

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Geriatrics

Caution

Ketotram Tablet should be given with caution in elderly patients due to an increased risk of side effects. It is important to inform your doctor before using it.

What if I have taken an overdose of Ketotram Tablet

If you suspect an overdose, seek emergency medical attention immediately. Signs of an overdose can include severely slowed breathing, extreme sleepiness, cold and clammy skin, pinpoint pupils, or loss of consciousness.

Diet & Lifestyle Advise

  • Stay hydrated: Drink plenty of water throughout the day to help your kidneys process the medication safely and to reduce the risk of constipation.
  • Eat high-fiber foods: To manage mild constipation caused by tramadol, include foods like whole grains, fruits, and vegetables in your daily diet.
  • Avoid alcohol completely: Do not drink alcohol while taking this medicine, as the combination can lead to dangerous sedation, breathing difficulties, and liver strain.
  • Protect your stomach: Avoid taking Ketotram Tablet on an empty stomach; a small meal or snack can prevent stomach lining irritation.
  • Rest and avoid strain: Give your body time to heal by avoiding heavy lifting or vigorous exercise while you are taking this medication for acute pain.
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How Soon It Starts Working

The time required for Ketotram Tablet to start to work: Ketotram Tablet ideally shows its action within 1 hour after administration. The time for which the effects of Ketotram Tablet last: The effect of Ketotram Tablet lasts for 6 to 8 hours.

What if you forget to take Ketotram Tablet

If you are taking this medicine on a regular schedule and miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular schedule. Do not take a double dose to make up for a missed one.

Storage

• Store Ketotram Tablet tablets at room temperature, ideally between 15°C and 30°C (59°F to 86°F).

Drug Warnings

  • Do not take this medication for longer than 5 days, as extended use increases the risk of serious kidney damage and stomach ulcers.
  • Avoid driving, operating heavy machinery, or performing dangerous tasks until you know how Ketotram Tablet affects you, as it can cause significant drowsiness and dizziness.
  • Do not take other NSAIDs (such as ibuprofen, naproxen, or aspirin) or other prescription pain relievers while using Ketotram Tablet unless your doctor explicitly tells you to do so.
  • If you have a history of asthma, monitor your breathing closely, as this medication can trigger or worsen breathing difficulties in sensitive individuals.
  • Always inform all of your healthcare providers, including dentists and surgeons, that you are taking Ketotram Tablet before undergoing any medical procedures.

Drug-Drug Interactions

verifiedApollotooltip

  • Blood thinners (like warfarin or aspirin): Taking these with Ketotram Tablet can significantly increase your risk of serious stomach and intestinal bleeding.

  • Other NSAIDs (like ibuprofen): Increases the risk of severe stomach ulcers and kidney damage.

  • Antidepressants (like SSRIs or MAOIs): May interact with tramadol to cause a rare but serious condition called serotonin syndrome, or increase your risk of seizures.

  • Sedatives and anxiety medicines: Combining these with Ketotram Tablet can lead to extreme drowsiness, breathing failure, or coma.

No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

verifiedApollotooltip
  • Alcohol: Greatly increases the risk of severe drowsiness, dangerously slow breathing, and stomach bleeding.
  • Grapefruit juice: May interfere with how your body processes tramadol, potentially raising the amount of medicine in your blood and increasing side effects.
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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All Substitutes & Brand Comparisons

Habit Forming

Yes

Therapeutic Class

[ANALGESICS]

FAQs

Ketotram Tablet belongs to the group of painkillers and analgesics used short-term to relieve moderate to severe pain.
Ketotram Tablet works by reducing the levels of prostaglandins (inflammatory markers), blocking the impulses of pain, relieving the body of inflammation and reducing the sensation of pain.
Ketotram Tablet should be used with caution in those suffering from asthma. Consult your doctor before use if you have asthma.
While Ketotram Tablet is safe for treating pain, Ketotram Tablet is not meant for long-term use because it can damage the kidneys and/or cause internal bleeding if used for longer durations.
No, Ketotram Tablet is not indicated as a painkiller during labour and delivery as it may cause uterine bleeding.
Ketotram Tablet is not indicated to treat headaches due to migraines. It is best to get your headache checked by a professional. Please consult your doctor in case of any concerns.
Yes, Ketotram Tablet can be used for toothache and to relieve pain after a dental procedure if prescribed by the doctor. Always follow the doctor’s instructions while using Ketotram Tablet .
Consult the doctor before using Ketotram Tablet with seizure medication as it may affect serotonin levels and can increase the risk of a serious condition called serotonin syndrome.
The common side effects of Ketotram Tablet include stomach ache, nausea, vomiting, gas, and dizziness. In most cases, these side effects are mild and temporary and will go away on their own over time. However, if these symptoms persist or worsen, it's important to consult with your doctor for further guidance and support.
It is not recommended to drive while taking this medicine. Ketotram Tablet can cause significant drowsiness, dizziness, and slow reaction times. Wait until you have finished your course of medication and feel completely alert before driving. Talk to your doctor if you have questions.
You should consult your healthcare provider before combining these medications. While paracetamol works differently, taking multiple pain relievers can strain your liver and kidneys. Talk to your doctor or pharmacist to get a safe, personalized pain relief plan.
Mild nausea is a common side effect. Taking your tablet with a meal, a snack, or a glass of milk can help prevent this. If the nausea is severe, causes vomiting, or does not go away, talk to your doctor.
This medicine is generally not recommended for breastfeeding mothers because the active ingredients can pass into breast milk and cause drowsiness or breathing problems in the baby. Talk to your doctor to discuss safer pain relief alternatives.
Yes, because Ketotram Tablet contains tramadol, which is an opioid, there is a potential risk of dependence and addiction, especially if it is used for longer than prescribed or in larger doses. Take it exactly as directed by your physician to minimize this risk.
If your pain remains severe or gets worse after taking the medication as prescribed, do not increase your dose on your own. Talk to your doctor, as they may need to re-evaluate your condition or adjust your treatment plan.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.

Reference

  1. U.S. Food and Drug Administration (FDA). 019645S019Lbl [FDA Prescribing Information]. Silver Spring, MD: FDA; 2024. [Accessed on 02 Jun. 2026]Check here
  2. DailyMed Database. Fdadrugxsl.Cfm Clinical Monograph. Bethesda, MD: National Library of Medicine; 2025. [Accessed on 02 Jun. 2026]Check here
  3. Mayo Clinic Staff. Drg 20066882 Inhalation and Dosage Monograph. Rochester, MN: Mayo Foundation for Medical Education; 2025. [Accessed on 02 Jun. 2026]Check here
  4. WebMD Medical Reference Review Board. Details Drug and Treatment Monograph. Atlanta, GA: WebMD; 2026. [Accessed on 02 Jun. 2026]Check here
  5. Electronic Medicines Compendium (EMC). Pil.7123 Patient Information Leaflet (PIL). Cheshire, UK: Datapharm; 2025. [Accessed on 02 Jun. 2026]Check here
  6. 6 1 Update. [Accessed on 02 Jun. 2026]Check here
  7. National Center for Biotechnology Information (NCBI). Pmc2811866 Scientific Research Publication. Bethesda, MD: NLM; 2025. [Accessed on 02 Jun. 2026]Check here

Country of origin

INDIA

Manufacturer/Marketer address

Medley House, D2, M.I.D.C. Area, Andheri (East), Mumbai-400 093, INDIA
Other Info - KET0341

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